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List of works by Joseph Leedale

A Combined In Vitro/In Silico Approach to Identifying Off-Target Receptor Toxicity

scientific article published on 29 June 2018

A dynamic, climate-driven model of Rift Valley fever

scientific article

Characterisation of a functional rat hepatocyte spheroid model

scientific article published on 20 December 2018

Environmental change and Rift Valley fever in eastern Africa: projecting beyond HEALTHY FUTURES.

scientific article

Impact of cell types and culture methods on the functionality of in vitro liver systems - A review of cell systems for hepatotoxicity assessment.

scientific article published in February 2018

Innovative organotypic in vitro models for safety assessment: aligning with regulatory requirements and understanding models of the heart, skin, and liver as paradigms.

scientific article published on 23 January 2018

Modeling the dynamics of hypoxia inducible factor-1α (HIF-1α) within single cells and 3D cell culture systems

scientific article

Modelling changes in glutathione homeostasis as a function of quinone redox metabolism

scientific article published on 19 April 2019

Modelling the impact of changes in the extracellular environment on the cytosolic free NAD+/NADH ratio during cell culture

scientific article published in PLoS ONE

Multiscale modelling of drug transport and metabolism in liver spheroids

scientific article published on 14 February 2020

Preparation of Primary Rat Hepatocyte Spheroids Utilizing the Liquid-Overlay Technique

scientific article published on 01 September 2019

Projecting malaria hazard from climate change in eastern Africa using large ensembles to estimate uncertainty

scientific article

Systems Toxicology Approach to Identifying Paracetamol Overdose.

scientific article

Tight control of hypoxia-inducible factor-α transient dynamics is essential for cell survival in hypoxia

scientific article published on 6 January 2014