List of works - Deborah H Fuller

Gene gun-based nucleic acid immunization: elicitation of humoral and cytotoxic T lymphocyte responses following epidermal delivery of nanogram quantities of DNA

scientific article published on 01 January 1995

Immunization of rhesus macaques with a DNA prime/modified vaccinia virus Ankara boost regimen induces broad simian immunodeficiency virus (SIV)-specific T-cell responses and reduces initial viral replication but does not prevent disease progression f

article

DNA Vaccines Expressing either the GP or NP Genes of Ebola Virus Protect Mice from Lethal Challenge

scientific article published on June 20, 1998

Use of DNAs expressing HIV-1 Env and noninfectious HIV-1 particles to raise antibody responses in mice.

scientific article published on May 1995

Vaccination with HIV-1 gp120 DNA induces immune responses that are boosted by a recombinant gp120 protein subunit

scientific article published on 01 June 1997

Examination of parameters affecting the elicitation of humoral immune responses by particle bombardment-mediated genetic immunization

scientific article published on 01 November 1993

Induction of mucosal protection against primary, heterologous simian immunodeficiency virus by a DNA vaccine

scientific article

Multispecific vaccine-induced mucosal cytotoxic T lymphocytes reduce acute-phase viral replication but fail in long-term control of simian immunodeficiency virus SIVmac239.

scientific article

A qualitative progression in HIV type 1 glycoprotein 120-specific cytotoxic cellular and humoral immune responses in mice receiving a DNA-based glycoprotein 120 vaccine

scientific article published on 01 November 1994

Plasmid vectors encoding cholera toxin or the heat-labile enterotoxin from Escherichia coli are strong adjuvants for DNA vaccines.

scientific article

Enhancement of immunodeficiency virus-specific immune responses in DNA-immunized rhesus macaques.

scientific article published in June 1997

Gene gun-based nucleic acid immunization alone or in combination with recombinant vaccinia vectors suppresses virus burden in rhesus macaques challenged with a heterologous SIV.

scientific article published in August 1997

GM-CSF increases mucosal and systemic immunogenicity of an H1N1 influenza DNA vaccine administered into the epidermis of non-human primates

scientific article (publication date: 8 June 2010)

Achieving Potent Autologous Neutralizing Antibody Responses against Tier 2 HIV-1 Viruses by Strategic Selection of Envelope Immunogens

scientific article published on 4 March 2016

Clinical safety and efficacy of a powdered Hepatitis B nucleic acid vaccine delivered to the epidermis by a commercial prototype device.

scientific article published in September 2005

Powder and particle-mediated approaches for delivery of DNA and protein vaccines into the epidermis

scientific article

Prospects for developing an effective particle-mediated DNA vaccine against influenza.

scientific article

Computational design of trimeric influenza-neutralizing proteins targeting the hemagglutinin receptor binding site.

scientific article

HIV-1 vaccine-induced immune responses which correlate with protection from SHIV infection: compiled preclinical efficacy data from trials with ten different HIV-1 vaccine candidates.

scientific article

Early cellular innate immune responses drive Zika viral persistence and tissue tropism in pigtail macaques

scientific article published in Nature Communications

A Computationally Designed Hemagglutinin Stem-Binding Protein Provides In Vivo Protection from Influenza Independent of a Host Immune Response

scientific article

Multigenic DNA vaccine induces protective cross-reactive T cell responses against heterologous influenza virus in nonhuman primates

scientific article published on 21 December 2017

Tolerability and immune responses in humans to a PowderJect DNA vaccine for hepatitis B

scientific article published on 01 January 2000

Evaluation of protection induced by a dengue virus serotype 2 envelope domain III protein scaffold/DNA vaccine in non-human primates.

scientific article

Effects of monotherapy with (R)-9-(2-phosphonylmethoxypropyl)adenine (PMPA) on the evolution of a primary Simian immunodeficiency virus (SIV) isolate.

scientific article published in August 2006

Kinetics of Myeloid-Derived Suppressor Cell Frequency and Function during Simian Immunodeficiency Virus Infection, Combination Antiretroviral Therapy, and Treatment Interruption.

scientific article published on 14 December 2016

'Omics investigations of HIV and SIV pathogenesis and innate immunity.

scientific article published on January 2013

Isolation, characterization, and functional analysis of ferret lymphatic endothelial cells.

scientific article

Laparoscopic Technique for Serial Collection of Para-Colonic, Left Colic, and Inferior Mesenteric Lymph Nodes in Macaques

scientific article

An alphavirus-derived replicon RNA vaccine induces SARS-CoV-2 neutralizing antibody and T cell responses in mice and nonhuman primates

scientific article published on 20 July 2020

Oral immunization with a live coxsackievirus/HIV recombinant induces gag p24-specific T cell responses

scientific article

Functional characterization of ferret CCL20 and CCR6 and identification of chemotactic inhibitors.

scientific article published on 27 January 2013

HIV vaccine trial exploits a dual and central role for innate immunity.

scientific article

Sustained AAV9-mediated expression of a non-self protein in the CNS of non-human primates after immunomodulation

scientific article

Complex Minigene Library Vaccination for Discovery of Pre-Erythrocytic Plasmodium T Cell Antigens

scientific article published on April 12, 2016

Mucosal T helper 17 and T regulatory cell homeostasis correlates with acute SIV viremia and responsiveness to antiretroviral therapy in macaques

scientific article published on 02 January 2019

Rapid progression is associated with lymphoid follicle dysfunction in SIV-infected infant rhesus macaques

scientific article published on 07 May 2021

De novo design of potent and resilient hACE2 decoys to neutralize SARS-CoV-2

scientific article published on 05 November 2020

Correction: Laparoscopic Technique for Serial Collection of Para-Colonic, Left Colic, and Inferior Mesenteric Lymph Nodes in Macaques

scientific article published on 2 January 2018

Engagement of monocytes, NK cells, and CD4+ Th1 cells by ALVAC-SIV vaccination results in a decreased risk of SIVmac251 vaginal acquisition

scientific article published on 12 March 2020

Immunotherapy as an adjunct to highly-active antiretroviral therapy

scientific article

Correction: Sustained AAV9-mediated expression of a non-self protein in the CNS of non-human primates after immunomodulation

scientific article published in PLoS ONE

List of works by Deborah H Fuller

Gene gun-based nucleic acid immunization: elicitation of humoral and cytotoxic T lymphocyte responses following epidermal delivery of nanogram quantities of DNA

Immunization of rhesus macaques with a DNA prime/modified vaccinia virus Ankara boost regimen induces broad simian immunodeficiency virus (SIV)-specific T-cell responses and reduces initial viral replication but does not prevent disease progression f

DNA Vaccines Expressing either the GP or NP Genes of Ebola Virus Protect Mice from Lethal Challenge

Use of DNAs expressing HIV-1 Env and noninfectious HIV-1 particles to raise antibody responses in mice.

Vaccination with HIV-1 gp120 DNA induces immune responses that are boosted by a recombinant gp120 protein subunit

Examination of parameters affecting the elicitation of humoral immune responses by particle bombardment-mediated genetic immunization

Induction of mucosal protection against primary, heterologous simian immunodeficiency virus by a DNA vaccine

Multispecific vaccine-induced mucosal cytotoxic T lymphocytes reduce acute-phase viral replication but fail in long-term control of simian immunodeficiency virus SIVmac239.

A qualitative progression in HIV type 1 glycoprotein 120-specific cytotoxic cellular and humoral immune responses in mice receiving a DNA-based glycoprotein 120 vaccine

Plasmid vectors encoding cholera toxin or the heat-labile enterotoxin from Escherichia coli are strong adjuvants for DNA vaccines.

Enhancement of immunodeficiency virus-specific immune responses in DNA-immunized rhesus macaques.

Gene gun-based nucleic acid immunization alone or in combination with recombinant vaccinia vectors suppresses virus burden in rhesus macaques challenged with a heterologous SIV.

GM-CSF increases mucosal and systemic immunogenicity of an H1N1 influenza DNA vaccine administered into the epidermis of non-human primates

Achieving Potent Autologous Neutralizing Antibody Responses against Tier 2 HIV-1 Viruses by Strategic Selection of Envelope Immunogens

Clinical safety and efficacy of a powdered Hepatitis B nucleic acid vaccine delivered to the epidermis by a commercial prototype device.

Powder and particle-mediated approaches for delivery of DNA and protein vaccines into the epidermis

Prospects for developing an effective particle-mediated DNA vaccine against influenza.

Computational design of trimeric influenza-neutralizing proteins targeting the hemagglutinin receptor binding site.

HIV-1 vaccine-induced immune responses which correlate with protection from SHIV infection: compiled preclinical efficacy data from trials with ten different HIV-1 vaccine candidates.

Early cellular innate immune responses drive Zika viral persistence and tissue tropism in pigtail macaques

A Computationally Designed Hemagglutinin Stem-Binding Protein Provides In Vivo Protection from Influenza Independent of a Host Immune Response

Multigenic DNA vaccine induces protective cross-reactive T cell responses against heterologous influenza virus in nonhuman primates

Tolerability and immune responses in humans to a PowderJect DNA vaccine for hepatitis B

Evaluation of protection induced by a dengue virus serotype 2 envelope domain III protein scaffold/DNA vaccine in non-human primates.

Effects of monotherapy with (R)-9-(2-phosphonylmethoxypropyl)adenine (PMPA) on the evolution of a primary Simian immunodeficiency virus (SIV) isolate.

Kinetics of Myeloid-Derived Suppressor Cell Frequency and Function during Simian Immunodeficiency Virus Infection, Combination Antiretroviral Therapy, and Treatment Interruption.

'Omics investigations of HIV and SIV pathogenesis and innate immunity.

Isolation, characterization, and functional analysis of ferret lymphatic endothelial cells.

Laparoscopic Technique for Serial Collection of Para-Colonic, Left Colic, and Inferior Mesenteric Lymph Nodes in Macaques

An alphavirus-derived replicon RNA vaccine induces SARS-CoV-2 neutralizing antibody and T cell responses in mice and nonhuman primates

Oral immunization with a live coxsackievirus/HIV recombinant induces gag p24-specific T cell responses

Functional characterization of ferret CCL20 and CCR6 and identification of chemotactic inhibitors.

HIV vaccine trial exploits a dual and central role for innate immunity.

Sustained AAV9-mediated expression of a non-self protein in the CNS of non-human primates after immunomodulation

Complex Minigene Library Vaccination for Discovery of Pre-Erythrocytic Plasmodium T Cell Antigens

Mucosal T helper 17 and T regulatory cell homeostasis correlates with acute SIV viremia and responsiveness to antiretroviral therapy in macaques

Rapid progression is associated with lymphoid follicle dysfunction in SIV-infected infant rhesus macaques

De novo design of potent and resilient hACE2 decoys to neutralize SARS-CoV-2

Correction: Laparoscopic Technique for Serial Collection of Para-Colonic, Left Colic, and Inferior Mesenteric Lymph Nodes in Macaques

Engagement of monocytes, NK cells, and CD4+ Th1 cells by ALVAC-SIV vaccination results in a decreased risk of SIVmac251 vaginal acquisition

Immunotherapy as an adjunct to highly-active antiretroviral therapy

Correction: Sustained AAV9-mediated expression of a non-self protein in the CNS of non-human primates after immunomodulation