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List of works by Fernando Ortega

A modular modulation method for achieving increases in metabolite production.

scientific article published on 23 March 2015

Effects of cadmium and mercury on the upper part of skeletal muscle glycolysis in mice

scientific article (publication date: 2014)

Elasticity analysis and design for large metabolic responses produced by changes in enzyme activities.

scientific article

Hepatic transcriptomic and metabolomic responses in the Stickleback (Gasterosteus aculeatus) exposed to ethinyl-estradiol.

scientific article

Hepatic transcriptomic profiles of European flounder (Platichthys flesus) from field sites and computational approaches to predict site from stress gene responses following exposure to model toxicants

scientific article published on 19 August 2008

Identifying health impacts of exposure to copper using transcriptomics and metabolomics in a fish model

scientific article published in January 2010

In silico strategy to rationally engineer metabolite production: A case study for threonine in Escherichia coli

scientific article published in June 2009

Interplay between α-, β-, and γ-secretases determines biphasic amyloid-β protein level in the presence of a γ-secretase inhibitor.

scientific article

Kinetic properties required for sustained or paradoxical control of metabolic fluxes under large changes in enzyme activities

scientific article published on 22 October 2007

Mapping drug physico-chemical features to pathway activity reveals molecular networks linked to toxicity outcome

scientific article

Mathematical modelling of the urea cycle. A numerical investigation into substrate channelling

scientific article published on October 2003

Models and computational strategies linking physiological response to molecular networks from large-scale data

scientific article

Modular metabolic control analysis of large responses in branched systems--application to aspartate metabolism.

scientific article published on 13 June 2011

Modular metabolic control analysis of large responses.

scientific article published in January 2007

New insights into our understanding of the regulation and organization of cell factories

scientific article published on 01 May 2000

Optimal Metabolic Control Design

scientific article published on April 21, 1998

Product dependence and bifunctionality compromise the ultrasensitivity of signal transduction cascades

scientific article

Rational cell culture optimization enhances experimental reproducibility in cancer cells

article

Sensitivity analysis of metabolic cascades catalyzed by bifunctional enzymes

article

Systems toxicology: modelling biomarkers of glutathione homeostasis and paracetamol metabolism

scientific article published on 16 July 2015

Transcriptomic responses of European flounder (Platichthys flesus) to model toxicants.

scientific article published on 15 August 2008