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List of works by Prajwal Gurung

A20 is a regulator of necroptosis

scientific article published in June 2015

ASK1/2 signaling promotes inflammation in a mouse model of neutrophilic dermatosis

scientific article published on 9 April 2018

Activation of the NLRP1b inflammasome independently of ASC-mediated caspase-1 autoproteolysis and speck formation

scientific article published on January 2014

Acute IL-4 Governs Pathogenic T Cell Responses during Leishmania major Infection

scientific article published on 18 September 2020

An NLRP3 inflammasome-triggered Th2-biased adaptive immune response promotes leishmaniasis

scientific article

An update on cell intrinsic negative regulators of the NLRP3 inflammasome.

scientific article published on 26 January 2018

Autoinflammatory Skin Disorders: The Inflammasomme in Focus

scientific article published on 03 June 2016

Cathepsin B modulates lysosomal biogenesis and host defense against Francisella novicida infection.

scientific article published on 22 August 2016

Chronic TLR Stimulation Controls NLRP3 Inflammasome Activation through IL-10 Mediated Regulation of NLRP3 Expression and Caspase-8 Activation

scientific article

Chronic ethanol induces inhibition of antigen-specific CD8+ but not CD4+ immunodominant T cell responses following Listeria monocytogenes inoculation

scientific article published on 26 September 2008

Concerted activation of the AIM2 and NLRP3 inflammasomes orchestrates host protection against Aspergillus infection

scientific article

Critical Role for the DNA Sensor AIM2 in Stem Cell Proliferation and Cancer

scientific article published on 18 June 2015

Critical role of caspase-8-mediated IL-1 signaling in promoting Th2 responses during asthma pathogenesis

scientific article published on 23 March 2016

Cutting Edge: Dysregulated CARD9 Signaling in Neutrophils Drives Inflammation in a Mouse Model of Neutrophilic Dermatoses

scholarly article by Sarang Tartey et al published 15 September 2018 in Journal of Immunology

Cutting edge: SHARPIN is required for optimal NLRP3 inflammasome activation

scientific article

Cutting edge: STING mediates protection against colorectal tumorigenesis by governing the magnitude of intestinal inflammation

scientific article

Dietary modulation of the microbiome affects autoinflammatory disease

scientific article

Distinct role of IL-1β in instigating disease in Sharpincpdm mice

scientific article

FADD and caspase-8 mediate priming and activation of the canonical and noncanonical Nlrp3 inflammasomes.

scientific article published on 22 January 2014

IL-10 engages macrophages to shift Th17 cytokine dependency and pathogenicity during T-cell-mediated colitis

scientific article

Immune responses against protozoan parasites: a focus on the emerging role of Nod-like receptors

scientific article published on 31 March 2016

Immune unresponsiveness to secondary heterologous bacterial infection after sepsis induction is TRAIL dependent

scientific article

Innate immune adaptor MyD88 deficiency prevents skin inflammation in SHARPIN-deficient mice

scientific article published on 23 July 2018

Innate immunity against Leishmania infections

scientific article

Leishmania major degrades murine CXCL1 - An immune evasion strategy

scientific article published on 01 July 2019

Microbiota and caspase-1/caspase-8 regulate IL-1β-mediated bone disease

scientific article published on 5 May 2016

Mitochondria: diversity in the regulation of the NLRP3 inflammasome

scientific article

NALP3 inflammasome upregulation and CASP1 cleavage of the glucocorticoid receptor cause glucocorticoid resistance in leukemia cells

scientific article published on 4 May 2015

NLRP3 inflammasome plays a redundant role with caspase 8 to promote IL-1β-mediated osteomyelitis

scientific article published on 6 April 2016

Neutro"feels" lethal toxin

scientific article published on 13 May 2020

Novel roles for caspase-8 in IL-1β and inflammasome regulation

scientific article

Protective roles for caspase-8 and cFLIP in adult homeostasis.

scientific article published on 03 October 2013

RIPK1 blocks early postnatal lethality mediated by caspase-8 and RIPK3

scientific article

Recent Advances in Lipopolysaccharide Recognition Systems

scientific article published on 07 January 2020

Reconciling protective and pathogenic roles of the NLRP3 inflammasome in leishmaniasis

scientific article published on 20 June 2020

Role of inflammasomes in host defense against Citrobacter rodentium infection

scientific article

Systemic immunological tolerance to ocular antigens is mediated by TRAIL-expressing CD8+ T cells.

scientific article

TAK1 restricts spontaneous NLRP3 activation and cell death to control myeloid proliferation.

scientific article

The NLRP12 Sensor Negatively Regulates Autoinflammatory Disease by Modulating Interleukin-4 Production in T Cells

scientific article

The magnitude of the T cell response to a clinically significant dose of influenza virus is regulated by TRAIL.

scientific article

The nonreceptor tyrosine kinase SYK drives caspase-8/NLRP3 inflammasome-mediated autoinflammatory osteomyelitis

scientific article published on 12 November 2019

Toll or interleukin-1 receptor (TIR) domain-containing adaptor inducing interferon-β (TRIF)-mediated caspase-11 protease production integrates Toll-like receptor 4 (TLR4) protein- and Nlrp3 inflammasome-mediated host defense against enteropathogens

scientific article

Tyrosine Kinase SYK Licenses MyD88 Adaptor Protein to Instigate IL-1α-Mediated Inflammatory Disease

scientific article