List of works - Ivana Cacciatore

(R)-α-lipoyl-glycyl-L-prolyl-L-glutamyl dimethyl ester codrug as a multifunctional agent with potential neuroprotective activities

scientific article published on 13 September 2012

2,5-diketopiperazines as neuroprotective agents.

scientific article

A Potent (R)-alpha-bis-lipoyl Derivative Containing 8-Hydroxyquinoline Scaffold: Synthesis and Biological Evaluation of Its Neuroprotective Capabilities in SH-SY5Y Human Neuroblastoma Cells

scientific article published on 7 January 2013

A glutathione derivative with chelating and in vitro neuroprotective activities: synthesis, physicochemical properties, and biological evaluation

scientific article published on 17 September 2013

Advances in prodrug design for Parkinson's disease

scientific article published on 23 January 2018

CNS delivery of l-dopa by a new hybrid glutathione–methionine peptidomimetic prodrug

scientific article published on 17 November 2010

Carvacrol Prodrugs with Antimicrobial Activity Loaded on Clay Nanocomposites

scientific article published on 10 April 2020

Carvacrol codrugs: a new approach in the antimicrobial plan

scientific article published in 2015

Carvacrol prodrugs as novel antimicrobial agents

scientific article published on 10 June 2019

Carvacrol reduces adipogenic differentiation by modulating autophagy and ChREBP expression

scientific article published in PLoS ONE

Codrugs linking L-dopa and sulfur-containing antioxidants: new pharmacological tools against Parkinson's disease.

scientific article

Conformationally constrained histidines in the design of peptidomimetics: strategies for the χ-space control. ⬇️

scientific article published on 03 May 2011

Cyclo(His-Pro) exerts anti-inflammatory effects by modulating NF-κB and Nrf2 signalling

scientific article published on 14 December 2011

Cyclo(His-Pro) inhibits NLRP3 inflammasome cascade in ALS microglial cells

scientific article published on 13 November 2018

Cyclo(His-Pro) promotes cytoprotection by activating Nrf2-mediated up-regulation of antioxidant defence.

scientific article published on 29 March 2008

Development of glycine-α-methyl-proline-containing tripeptides with neuroprotective properties

scientific article published on 10 December 2015

Development of l-Dopa-containing diketopiperazines as blood-brain barrier shuttle

scientific article published in 2022

Discovery of small molecule vanin inhibitors: new tools to study metabolism and disease.

scientific article

Effect of MRJF4 on C6 Glioma Cells Proliferation and Migration

scientific article published on 23 August 2016

Efficacy of the Quorum Sensing Inhibitor FS10 Alone and in Combination with Tigecycline in an Animal Model of Staphylococcal Infected Wound

scientific article

Gold nanoparticles as scaffolds for poor water soluble and difficult to vehiculate antiparkinson codrugs.

scientific article published on 6 December 2016

Haloperidol metabolite II prodrug: asymmetric synthesis and biological evaluation on rat C6 glioma cells.

scientific article published on 6 November 2014

Ibuprofen and glutathione conjugate as a potential therapeutic agent for treating Alzheimer's disease.

scientific article published on 22 December 2010

L-dopa co-drugs in nanostructured lipid carriers: A comparative study.

scientific article published on 18 November 2016

Memantine-derived drugs as potential antitumor agents for the treatment of glioblastoma

scientific article

Memantine-sulfur containing antioxidant conjugates as potential prodrugs to improve the treatment of Alzheimer's disease

scientific article published on 27 February 2013

Modulation of Apoptotic Cell Death and Neuroprotective Effects of Glutathione-L-Dopa Codrug Against H2O2-Induced Cellular Toxicity

scientific article published on 19 August 2019

N-acetyl-L-methionyl-L-Dopa-methyl ester as a dual acting drug that relieves L-Dopa-induced oxidative toxicity.

scientific article published on 20 March 2010

Nanoencapsulation strategies for the delivery of novel bifunctional antioxidant/σ1 selective ligands.

scientific article published on 12 April 2017

Neuroinflammation and endoplasmic reticulum stress are coregulated by cyclo(His-Pro) to prevent LPS neurotoxicity

scientific article published on 31 March 2014

New L-dopa codrugs as potential antiparkinson agents

scientific article published in July 2008

New bifunctional antioxidant/σ1 agonist ligands: Preliminary chemico-physical and biological evaluation

scientific article

New flurbiprofen derivatives: synthesis, membrane affinity and evaluation of in vitro effect on β-amyloid levels

scientific article published on 3 September 2013

Novel NSAID-Derived Drugs for the Potential Treatment of Alzheimer's Disease

scientific article

Novel anti-Alzheimer phenol-lipoyl hybrids: Synthesis, physico-chemical characterization, and biological evaluation

scientific article published on 12 November 2019

PPARalpha regulates the production of serum Vanin-1 by liver

scientific article published on 15 October 2013

Potent isozyme-selective inhibition of human glutathione S-transferase A1-1 by a novel glutathione S-conjugate.

scientific article published on 8 August 2005

Preparation and characterization of polymeric micelles loaded with a potential anticancer prodrug

Preparation and pharmacological characterization of trans-2-amino-5(6)-fluoro-6(5)-hydroxy-1-phenyl-2,3-dihydro-1H-indenes as D2-like dopamine receptor agonists

scientific article published in April 2005

Prodrug approach for increasing cellular glutathione levels

scientific article published on 03 March 2010

RNAIII Inhibiting Peptide (RIP) and Derivatives as Potential Tools for the Treatment of S. aureus Biofilm Infections

article

Recent Tools to Overcome Antibacterial Resistance

scientific article published on 01 January 2018

Role of Dietary Supplements in the Management of Parkinson's Disease

scientific article published on 10 July 2019

Solid lipid nanoparticles as a drug delivery system for the treatment of neurodegenerative diseases.

scientific article published on 13 April 2016

Solid lipid nanoparticles loaded with lipoyl-memantine codrug: preparation and characterization.

scientific article published on 4 March 2015

Synthesis and Biological Evaluation of Novel Selenyl and Sulfur-l-Dopa Derivatives as Potential Anti-Parkinson's Disease Agents

scientific article published on 18 June 2019

Synthesis and activity of endomorphin-2 and morphiceptin analogues with proline surrogates in position 2 ⬇️

scientific article published on July 21, 2010

Synthesis and activity of novel glutathione analogues containing an urethane backbone linkage.

scientific article published in September 2003

Synthesis and preliminary pharmacological evaluation of trans-2-amino-5(6)-chloro-6(5)-hydroxy-1-phenyl-2,3-dihydro-1H-indenes as dopamine receptor ligands

scientific article

Synthesis of a novel cyclic prodrug of S-allyl-glutathione able to attenuate LPS-induced ROS production through the inhibition of MAPK pathways in U937 cells

scientific article

Synthesis of short cationic antimicrobial peptidomimetics containing arginine analogues.

scientific article

The efficacy of the quorum sensing inhibitor FS8 and tigecycline in preventing prosthesis biofilm in an animal model of staphylococcal infection

scientific article published on 07 August 2013

Toxicity assessment of hydroxyapatite nanoparticles in rat liver cell model in vitro

scientific article

Transition state isosteres of the gamma-glutamyl peptide bond hydrolysis: synthesis and characterization of the psi (CH2NH) pseudopeptide analogue of glutathione.

scientific article published in February 2004

List of works by Ivana Cacciatore

(R)-α-lipoyl-glycyl-L-prolyl-L-glutamyl dimethyl ester codrug as a multifunctional agent with potential neuroprotective activities

2,5-diketopiperazines as neuroprotective agents.

A Potent (R)-alpha-bis-lipoyl Derivative Containing 8-Hydroxyquinoline Scaffold: Synthesis and Biological Evaluation of Its Neuroprotective Capabilities in SH-SY5Y Human Neuroblastoma Cells

A glutathione derivative with chelating and in vitro neuroprotective activities: synthesis, physicochemical properties, and biological evaluation

Advances in prodrug design for Parkinson's disease

CNS delivery of l-dopa by a new hybrid glutathione–methionine peptidomimetic prodrug

Carvacrol Prodrugs with Antimicrobial Activity Loaded on Clay Nanocomposites

Carvacrol codrugs: a new approach in the antimicrobial plan

Carvacrol prodrugs as novel antimicrobial agents

Carvacrol reduces adipogenic differentiation by modulating autophagy and ChREBP expression

Codrugs linking L-dopa and sulfur-containing antioxidants: new pharmacological tools against Parkinson's disease.

Conformationally constrained histidines in the design of peptidomimetics: strategies for the χ-space control. ⬇️

Cyclo(His-Pro) exerts anti-inflammatory effects by modulating NF-κB and Nrf2 signalling

Cyclo(His-Pro) inhibits NLRP3 inflammasome cascade in ALS microglial cells

Cyclo(His-Pro) promotes cytoprotection by activating Nrf2-mediated up-regulation of antioxidant defence.

Development of glycine-α-methyl-proline-containing tripeptides with neuroprotective properties

Development of l-Dopa-containing diketopiperazines as blood-brain barrier shuttle

Discovery of small molecule vanin inhibitors: new tools to study metabolism and disease.

Effect of MRJF4 on C6 Glioma Cells Proliferation and Migration

Efficacy of the Quorum Sensing Inhibitor FS10 Alone and in Combination with Tigecycline in an Animal Model of Staphylococcal Infected Wound

Gold nanoparticles as scaffolds for poor water soluble and difficult to vehiculate antiparkinson codrugs.

Haloperidol metabolite II prodrug: asymmetric synthesis and biological evaluation on rat C6 glioma cells.

Ibuprofen and glutathione conjugate as a potential therapeutic agent for treating Alzheimer's disease.

L-dopa co-drugs in nanostructured lipid carriers: A comparative study.

Memantine-derived drugs as potential antitumor agents for the treatment of glioblastoma

Memantine-sulfur containing antioxidant conjugates as potential prodrugs to improve the treatment of Alzheimer's disease

Modulation of Apoptotic Cell Death and Neuroprotective Effects of Glutathione-L-Dopa Codrug Against H2O2-Induced Cellular Toxicity

N-acetyl-L-methionyl-L-Dopa-methyl ester as a dual acting drug that relieves L-Dopa-induced oxidative toxicity.

Nanoencapsulation strategies for the delivery of novel bifunctional antioxidant/σ1 selective ligands.

Neuroinflammation and endoplasmic reticulum stress are coregulated by cyclo(His-Pro) to prevent LPS neurotoxicity

New L-dopa codrugs as potential antiparkinson agents

New bifunctional antioxidant/σ1 agonist ligands: Preliminary chemico-physical and biological evaluation

New flurbiprofen derivatives: synthesis, membrane affinity and evaluation of in vitro effect on β-amyloid levels

Novel NSAID-Derived Drugs for the Potential Treatment of Alzheimer's Disease

Novel anti-Alzheimer phenol-lipoyl hybrids: Synthesis, physico-chemical characterization, and biological evaluation

PPARalpha regulates the production of serum Vanin-1 by liver

Potent isozyme-selective inhibition of human glutathione S-transferase A1-1 by a novel glutathione S-conjugate.

Preparation and characterization of polymeric micelles loaded with a potential anticancer prodrug

Preparation and pharmacological characterization of trans-2-amino-5(6)-fluoro-6(5)-hydroxy-1-phenyl-2,3-dihydro-1H-indenes as D2-like dopamine receptor agonists

Prodrug approach for increasing cellular glutathione levels

RNAIII Inhibiting Peptide (RIP) and Derivatives as Potential Tools for the Treatment of S. aureus Biofilm Infections

Recent Tools to Overcome Antibacterial Resistance

Role of Dietary Supplements in the Management of Parkinson's Disease

Solid lipid nanoparticles as a drug delivery system for the treatment of neurodegenerative diseases.

Solid lipid nanoparticles loaded with lipoyl-memantine codrug: preparation and characterization.

Synthesis and Biological Evaluation of Novel Selenyl and Sulfur-l-Dopa Derivatives as Potential Anti-Parkinson's Disease Agents

Synthesis and activity of endomorphin-2 and morphiceptin analogues with proline surrogates in position 2 ⬇️

Synthesis and activity of novel glutathione analogues containing an urethane backbone linkage.

Synthesis and preliminary pharmacological evaluation of trans-2-amino-5(6)-chloro-6(5)-hydroxy-1-phenyl-2,3-dihydro-1H-indenes as dopamine receptor ligands

Synthesis of a novel cyclic prodrug of S-allyl-glutathione able to attenuate LPS-induced ROS production through the inhibition of MAPK pathways in U937 cells

Synthesis of short cationic antimicrobial peptidomimetics containing arginine analogues.

The efficacy of the quorum sensing inhibitor FS8 and tigecycline in preventing prosthesis biofilm in an animal model of staphylococcal infection

Toxicity assessment of hydroxyapatite nanoparticles in rat liver cell model in vitro

Transition state isosteres of the gamma-glutamyl peptide bond hydrolysis: synthesis and characterization of the psi (CH2NH) pseudopeptide analogue of glutathione.