List of works by Romina Alfonsi

Chemical, computational and functional insights into the chemical stability of the Hedgehog pathway inhibitor GANT61.

scientific article published in December 2018

Design, Palladium-Catalyzed Synthesis, and Biological Investigation of 2-Substituted 3-Aroylquinolin-4(1H)-ones as Inhibitors of the Hedgehog Signaling Pathway.

scientific article published on 25 January 2017

Diagnostic and prognostic potential of the proteomic profiling of serum-derived extracellular vesicles in prostate cancer

scientific article published on 21 June 2021

Gli1/DNA interaction is a druggable target for Hedgehog-dependent tumors.

scientific article

Hypomorphic Recessive Variants in SUFU Impair the Sonic Hedgehog Pathway and Cause Joubert Syndrome with Cranio-facial and Skeletal Defects.

scientific article published on 27 September 2017

Inhibition of Hedgehog-dependent tumors and cancer stem cells by a newly identified naturally occurring chemotype

scientific article

Insights into Gli Factors Ubiquitylation Methods.

scientific article published on January 2015

Itch/β-arrestin2-dependent non-proteolytic ubiquitylation of SuFu controls Hedgehog signalling and medulloblastoma tumorigenesis.

scientific article published on 7 March 2018

MK-4101, a Potent Inhibitor of the Hedgehog Pathway, Is Highly Active against Medulloblastoma and Basal Cell Carcinoma

scientific article

New Indole Tubulin Assembly Inhibitors Cause Stable Arrest of Mitotic Progression, Enhanced Stimulation of Natural Killer Cell Cytotoxic Activity, and Repression of Hedgehog-Dependent Cancer

scientific article

New pyrrole derivatives with potent tubulin polymerization inhibiting activity as anticancer agents including hedgehog-dependent cancer

scientific article

Organoids as a new model for improving regenerative medicine and cancer personalized therapy in renal diseases

scientific article published on 27 February 2019

PCAF ubiquitin ligase activity inhibits Hedgehog/Gli1 signaling in p53-dependent response to genotoxic stress

scientific article published on 6 September 2013

Renal cancer: new models and approach for personalizing therapy

scientific article published on 05 September 2018

Synergistic inhibition of the Hedgehog pathway by newly designed Smo and Gli antagonists bearing the isoflavone scaffold

scientific article published on 09 July 2018

Targeting GLI factors to inhibit the Hedgehog pathway.

scientific article published on 10 June 2015

The Double Face of Exosome-Carried MicroRNAs in Cancer Immunomodulation.

scientific article published on 13 April 2018

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