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List of works by Chandy C. John

A family cluster of five cases of group A streptococcal pneumonia

scientific article published in July 2003

Accurate Diagnosis of Cerebral Malaria: A Role for Parasite Histidine-Rich Protein 2? ⬇️

scientific article published on May 25, 2012

Acute Kidney Injury Is Common in Pediatric Severe Malaria and Is Associated With Increased Mortality

scientific article published on 26 February 2016

Adjunctive therapy for cerebral malaria and other severe forms of Plasmodium falciparum malaria ⬇️

scientific article published on September 1, 2010

Admission EEG findings in diverse paediatric cerebral malaria populations predict outcomes.

scientific article

Alterations in Systemic Extracellular Heme and Hemopexin Are Associated With Adverse Clinical Outcomes in Ugandan Children With Severe Malaria

scientific article published on 11 August 2016

Antibodies to Plasmodium falciparum antigens predict a higher risk of malaria but protection from symptoms once parasitemic

scientific article

Antibodies to Plasmodium falciparum antigens vary by age and antigen in children in a malaria-holoendemic area of Kenya

scientific article published in August 2005

Antibodies to Plasmodium falciparum erythrocyte-binding antigen-175 are associated with protection from clinical malaria

scientific article published on December 2011

Antibodies to pre-erythrocytic Plasmodium falciparum antigens and risk of clinical malaria in Kenyan children

scientific article published on February 2008

Antibodies to the Plasmodium falciparum antigens circumsporozoite protein, thrombospondin-related adhesive protein, and liver-stage antigen 1 vary by ages of subjects and by season in a highland area of Kenya

scientific article

Asymptomatic Malaria and Other Infections in Children Adopted from Ethiopia, United States, 2006-2011.

scientific article published on July 2015

Brain Death Secondary to Rocky Mountain Spotted Fever Encephalitis

scientific article published on 01 May 2020

COVID-19: Shining the Light on Africa

scientific article published on 05 May 2020

Cerebral malaria in children is associated with long-term cognitive impairment

scientific article published on 09 June 2008

Cerebral malaria is associated with long-term mental health disorders: a cross sectional survey of a long-term cohort

scientific article published on 31 March 2016

Cerebral malaria pathogenesis: what can we learn from microarray analysis?

scientific article published on 8 November 2007

Cerebral malaria: mechanisms of brain injury and strategies for improved neurocognitive outcome

scientific article published in October 2010

Cerebrospinal fluid cytokine levels and cognitive impairment in cerebral malaria.

scientific article

Cerebrospinal fluid kynurenine and kynurenic acid concentrations are associated with coma duration and long-term neurocognitive impairment in Ugandan children with cerebral malaria

scientific article published on 28 July 2017

Changes in B Cell Populations and Merozoite Surface Protein-1-Specific Memory B Cell Responses after Prolonged Absence of Detectable P. falciparum Infection ⬇️

scientific article published on June 27, 2013

Changes in antigen-specific cytokine and chemokine responses to Plasmodium falciparum antigens in a highland area of Kenya after a prolonged absence of malaria exposure

scientific article

Characterization of immunoglobulin G antibodies to Plasmodium falciparum sporozoite surface antigen MB2 in malaria exposed individuals

scientific article

Chitinase-3-like 1 is a biomarker of acute kidney injury and mortality in paediatric severe malaria

scientific article published on 15 February 2018

Clinical Comparison of Retinopathy-Positive and Retinopathy-Negative Cerebral Malaria

scientific article published on 30 January 2017

Clinical Features of Critical Coronavirus Disease 2019 in Children

scientific article published on 02 July 2020

Clinical manifestations of severe malaria in the highlands of southwestern Uganda.

scientific article published on May 2005

Cognition, behaviour and academic skills after cognitive rehabilitation in Ugandan children surviving severe malaria: a randomised trial

scientific article

Cognitive impairment after cerebral malaria in children: a prospective study

scientific article published on 15 January 2007

Comparison of iron status 28 d after provision of antimalarial treatment with iron therapy compared with antimalarial treatment alone in Ugandan children with severe malaria

scientific article published on 3 February 2016

Complex interactions of HIV infection, malaria, and iron deficiency

scientific article published on 15 August 2013

Correlation of high levels of antibodies to multiple pre-erythrocytic Plasmodium falciparum antigens and protection from infection.

scientific article published in July 2005

Decline in childhood iron deficiency after interruption of malaria transmission in highland Kenya

scientific article

Decreased prevalence of anemia in highland areas of low malaria transmission after a 1-year interruption of transmission

scientific article

Delaying Iron Therapy until 28 Days after Antimalarial Treatment Is Associated with Greater Iron Incorporation and Equivalent Hematologic Recovery after 56 Days in Children: A Randomized Controlled Trial.

scientific article published on 29 June 2016

Delaying the start of iron until 28 days after antimalarial treatment is associated with lower incidence of subsequent illness in children with malaria and iron deficiency

scientific article published on 30 August 2017

Developing mentorship in a resource-limited context: a qualitative research study of the experiences and perceptions of the makerere university student and faculty mentorship programme

scientific article

Development of a Competency-Based Curriculum in Global Child Health ⬇️

scientific article published on April 1, 2011

Development of clinical immunity to malaria in highland areas of low and unstable transmission

scientific article

Diagnosing latent tuberculosis in international adoptees remains challenging

scientific article published on November 1, 2011

Differing Causes of Lactic Acidosis and Deep Breathing in Cerebral Malaria and Severe Malarial Anemia May Explain Differences in Acidosis-Related Mortality

scientific article

Drug treatment of malaria in children

scientific article

Editorial Commentary: Toward a Better Malaria Vaccine: Understanding How Antibodies to Malaria Protect Against Disease

scientific article

Effect of transmission intensity and age on subclass antibody responses to Plasmodium falciparum pre-erythrocytic and blood-stage antigens

scientific article

Efficacy model for antibody-mediated pre-erythrocytic malaria vaccines

scientific article published on 13 October 2010

Elevated cerebrospinal fluid tumour necrosis factor is associated with acute and long-term neurocognitive impairment in cerebral malaria

scientific article published on 28 April 2017

Elevated serum levels of IL-1ra in children with Plasmodium falciparum malaria are associated with increased severity of disease

scientific article published on 20 February 2008

Environmental, socio-demographic and behavioural determinants of malaria risk in the western Kenyan highlands: a case-control study

scientific article

Essential factors for the development of a residency global health track

scientific article published on 2 July 2012

Estimation of recent and long-term malaria transmission in a population by antibody testing to multiple Plasmodium falciparum antigens

scientific article

Evidence of Endothelial Activation in Asymptomatic Plasmodium falciparum Parasitemia and Effect of Blood Group on Levels of von Willebrand Factor in Malaria ⬇️

scientific article published on March 1, 2012

Evidence that invasion-inhibitory antibodies specific for the 19-kDa fragment of merozoite surface protein-1 (MSP-1 19) can play a protective role against blood-stage Plasmodium falciparum infection in individuals in a malaria endemic area of Africa

scientific article published in July 2004

Expanding the toolbox in pursuit of a strain transcendent malaria vaccine

scientific article published on 24 November 2014

Exploring experimental cerebral malaria pathogenesis through the characterisation of host-derived plasma microparticle protein content

scientific article published on 05 December 2016

Gamma interferon responses to Plasmodium falciparum liver-stage antigen 1 and thrombospondin-related adhesive protein and their relationship to age, transmission intensity, and protection against malaria

scientific article published on September 2004

Global research priorities for infections that affect the nervous system

scientific article

Hepatitis a screening for internationally adopted children from hepatitis A endemic countries

scientific article published on 17 October 2013

High Postdischarge Morbidity in Ugandan Children With Severe Malarial Anemia or Cerebral Malaria

scientific article

High plasma erythropoietin levels are associated with prolonged coma duration and increased mortality in children with cerebral malaria

scientific article

High rate of inappropriate blood transfusions in the management of children with severe anemia in Ugandan hospitals

scholarly article by Robert O Opoka et al published 18 July 2018 in BMC Health Services Research

Host Biomarkers Are Associated With Response to Therapy and Long-Term Mortality in Pediatric Severe Malaria

scientific article published on 20 June 2016

Humoral and Cellular Immunity to Plasmodium falciparum Merozoite Surface Protein 1 and Protection From Infection With Blood-Stage Parasites ⬇️

scientific article published on March 28, 2013

Hydroxyurea Dose Escalation for Sickle Cell Anemia in Sub-Saharan Africa

scientific article published on 01 June 2020

Immediate neuropsychological and behavioral benefits of computerized cognitive rehabilitation in Ugandan pediatric cerebral malaria survivors

scientific article published on August 2009

Immunomodulation inPlasmodium falciparummalaria: experiments in nature and their conflicting implications for potential therapeutic agents ⬇️

scientific article published on November 1, 2012

Infections in Internationally Adopted Children ⬇️

scientific article published on February 1, 2013

Inhaled nitric oxide and cognition in pediatric severe malaria: A randomized double-blind placebo controlled trial

scientific article published on 25 January 2018

Inhaled nitric oxide for the adjunctive therapy of severe malaria: protocol for a randomized controlled trial

scientific article published on 13 July 2011

Inpatient mortality in children with clinically diagnosed malaria as compared with microscopically confirmed malaria

scientific article published on April 2008

Interferon-gamma responses to Plasmodium falciparum liver-stage antigen-1 and merozoite-surface protein-1 increase with age in children in a malaria holoendemic area of western Kenya ⬇️

scientific article published on November 5, 2003

Interferon-γ responses to Plasmodium falciparum vaccine candidate antigens decrease in the absence of malaria transmission

scientific article published on 10 January 2017

Iron, Inflammation, and Malaria in the Pregnant Woman and Her Child: Saving Lives, Saving Brains

scientific article published on August 2016

Keep Politics out of Funding Decisions for Medical Research and Public Health

scientific article published on 22 July 2020

Lack of mortality in 22 children with sickle cell anemia and severe malarial anemia

scientific article published on 17 August 2017

Local topographic wetness indices predict household malaria risk better than land-use and land-cover in the western Kenya highlands

scientific article

Longevity of Genotype-Specific Immune Responses to Plasmodium falciparum Merozoite Surface Protein 1 in Kenyan Children from Regions of Different Malaria Transmission Intensity

scientific article published on August 2016

Low levels of RANTES are associated with mortality in children with cerebral malaria

scientific article published on 16 August 2006

Low prevalence of Plasmodium falciparum infection among asymptomatic individuals in a highland area of Kenya

scientific article published in October 2005

Low prevalence of antibodies to preerythrocytic but not blood-stage Plasmodium falciparum antigens in an area of unstable malaria transmission compared to prevalence in an area of stable malaria transmission

scientific article published on 22 September 2008

Lymphocyte proliferation and antibody responses to Plasmodium falciparum liver-stage antigen-1 in a highland area of Kenya with seasonal variation in malaria transmission.

scientific article published in April 2002

Malaria hotspot areas in a highland Kenya site are consistent in epidemic and non-epidemic years and are associated with ecological factors

scientific article

Malaria treatment-seeking behaviour and recovery from malaria in a highland area of Kenya

scientific article

Malaria with neurological involvement in Ugandan children: effect on cognitive ability, academic achievement and behaviour

scientific article published on 3 November 2011

Methemoglobin and nitric oxide therapy in Ugandan children hospitalized for febrile illness: results from a prospective cohort study and randomized double-blind placebo-controlled trial

scientific article

Microscopy underestimates the frequency of Plasmodium falciparum infection in symptomatic individuals in a low transmission highland area

scientific article published on August 2008

Neurocognitive domains affected by cerebral malaria and severe malarial anemia in children

scientific article published on 16 January 2015

Neurodevelopment: The Impact of Nutrition and Inflammation During Early to Middle Childhood in Low-Resource Settings

scientific article

Nitric oxide for the adjunctive treatment of severe malaria: hypothesis and rationale

scientific article

Novel Use of Hydroxyurea in an African Region With Malaria: Protocol for a Randomized Controlled Clinical Trial

scientific article published on 23 June 2016

Novel use Of Hydroxyurea in an African Region with Malaria (NOHARM): a trial for children with sickle cell anemia

scientific article

Pediatric infectious diseases

scientific article published on 21 January 2013

Performance of point-of-care diagnostics for glucose, lactate, and hemoglobin in the management of severe malaria in a resource-constrained hospital in Uganda

scientific article published on 03 March 2014

Plasmodium falciparum EPCR-binding PfEMP1 expression increases with malaria disease severity and is elevated in retinopathy negative cerebral malaria

scientific article published on 13 October 2017

Plasmodium falciparum Histidine-Rich Protein-2 Plasma Concentrations Are Higher in Retinopathy-Negative Cerebral Malaria Than in Severe Malarial Anemia

scientific article published on 22 July 2017

Possible interruption of malaria transmission, highland Kenya, 2007-2008.

scientific article

Prevalence of Asymptomatic SARS-CoV-2 Infection in Children and Adults in Marion County, Indiana

scientific article published on 16 August 2020

Primaquine plus artemisinin combination therapy for reduction of malaria transmission: promise and risk

scientific article published on April 2016

Prospective validation of pediatric disease severity scores to predict mortality in Ugandan children presenting with malaria and non-malaria febrile illness

scientific article

Recurrent Plasmodium falciparum Malaria Infections in Kenyan Children Diminish T-Cell Immunity to Epstein Barr Virus Lytic but Not Latent Antigens ⬇️

scientific article published on March 12, 2012

Recurrent fever in children

scientific article

Rehabilitation for cognitive impairments after cerebral malaria in African children: strategies and limitations

scientific article published on September 2006

Reliability of the Luganda version of the Child Behaviour Checklist in measuring behavioural problems after cerebral malaria

scientific article published on 8 December 2009

Reply to Eisenhut

scientific article published on 19 December 2014

Risk of Plasmodium falciparum infection during a malaria epidemic in highland Kenya, 1997.

scientific article

Sensitivity of fever for diagnosis of clinical malaria in a Kenyan area of unstable, low malaria transmission

scientific article

Serum angiopoietin-1 and -2 levels discriminate cerebral malaria from uncomplicated malaria and predict clinical outcome in African children

scientific article

Severe malarial anemia is associated with long-term neurocognitive impairment

scientific article

Slow Clearance of Plasmodium falciparum in Severe Pediatric Malaria, Uganda, 2011-2013.

scientific article published on July 2015

Socioeconomic predictors of cognition in Ugandan children: implications for community interventions

scientific article

Stability of interferon-gamma and interleukin-10 responses to Plasmodium falciparum liver stage antigen 1 and thrombospondin-related adhesive protein immunodominant epitopes in a highland population from Western Kenya

scientific article published on September 2009

Stability of interferon-gamma and interleukin-10 responses to Plasmodium falciparum liver stage antigen-1 and thrombospondin-related adhesive protein in residents of a malaria holoendemic area

scientific article

Standardization and validation of a cytometric bead assay to assess antibodies to multiple Plasmodium falciparum recombinant antigens

scientific article published on 21 December 2012

Staphylococcal toxic shock syndrome erythroderma is associated with superantigenicity and hypersensitivity

scientific article published on December 2009

Statistical Approaches to Assess the Effects of Disease on Neurocognitive Function Over Time

scientific article

Successful Global Health Research Partnerships: What Makes Them Work?

scientific article

Supporting Global Health at the Pediatric Department Level: Why and How.

scientific article published on 3 May 2017

TLR9 polymorphisms are associated with altered IFN-gamma levels in children with cerebral malaria

scientific article

The Benjamin H. Kean Travel Fellowship in Tropical Medicine: Assessment of Impact at 15 Years

scientific article

The Collaborative Role of North American Departments of Pediatrics in Global Child Health

article

The Plasmodium falciparum Antigen MB2 Induces Interferon-γ and Interleukin-10 Responses in Adults in Malaria Endemic Areas of Western Kenya

scientific article published on October 2013

The association between cognition and academic performance in Ugandan children surviving malaria with neurological involvement

scientific article

The endothelial protein C receptor rs867186-GG genotype is associated with increased soluble EPCR and could mediate protection against severe malaria

scientific article published on 03 June 2016

The impact of delayed treatment of uncomplicated P. falciparum malaria on progression to severe malaria: A systematic review and a pooled multicentre individual-patient meta-analysis

scientific article published on 19 October 2020

The prevalence and density of asymptomatic Plasmodium falciparum infections among children and adults in three communities of western Kenya

scientific article published on 17 September 2021

Therapies and vaccines for emerging bacterial infections: learning from methicillin-resistant Staphylococcus aureus

scientific article published on August 2006

Thrombocytopenia May Mediate Disease Severity in Plasmodium falciparum Malaria Through Reduced Transforming Growth Factor Beta-1 Regulation of Proinflammatory and Anti-inflammatory Cytokines

scientific article

Toll-like receptor polymorphisms and cerebral malaria: TLR2 Δ22 polymorphism is associated with protection from cerebral malaria in a case control study ⬇️

scientific article published on February 15, 2012

Use of a three-band HRP2/pLDH combination rapid diagnostic test increases diagnostic specificity for falciparum malaria in Ugandan children

scientific article published on February 2014

Use of pre-hospital medication in children presenting with malaria to the emergency unit of Mulago Hospital, Uganda: A descriptive study

scientific article

Vitamin D insufficiency is common in Ugandan children and is associated with severe malaria

scientific article

Zinc for Infection Prevention in Sickle Cell Anemia (ZIPS): study protocol for a randomized placebo-controlled trial in Ugandan children with sickle cell anemia

scientific article published on 26 July 2019

[Formula: see text]Selecting measures for the neurodevelopmental assessment of children in low- and middle-income countries

scientific article published on 9 September 2016

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