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List of works by Russell E Ware

A Clinically Meaningful Fetal Hemoglobin Threshold for Children with Sickle Cell Anemia During Hydroxyurea Therapy.

scientific article published on 14 September 2017

A Cost-Effectiveness Analysis of a Pilot Neonatal Screening Program for Sickle Cell Anemia in the Republic of Angola.

scientific article

A Phase 3 Randomized Trial of Voxelotor in Sickle Cell Disease

scientific article published on 14 June 2019

A novel G6PD mutation leading to chronic hemolytic anemia

scientific article published on December 2008

A novel laboratory technique demonstrating the influences of RHD zygosity and the RhCcEe phenotype on erythrocyte D antigen expression ⬇️

scientific article published on November 25, 2011

A pilot study of hydroxyurea to prevent chronic organ damage in young children with sickle cell anemia.

scientific article published on May 2009

A pilot study of subcutaneous decitabine in β-thalassemia intermedia ⬇️

scientific article published on June 23, 2011

A prospective newborn screening and treatment program for sickle cell anemia in Luanda, Angola

scientific article published on 15 October 2013

Acute parvovirus B19 infection mimicking congenital dyserythropoietic anemia

scientific article published in February 2004

An accurate and inexpensive color-based assay for detecting severe anemia in a limited-resource setting

scientific article

AnemoCheck-LRS: an optimized, color-based point-of-care test to identify severe anemia in limited-resource settings

scientific article published on 16 November 2020

Arterial spin-labeled perfusion combined with segmentation techniques to evaluate cerebral blood flow in white and gray matter of children with sickle cell anemia

scientific article published on January 2009

Bone marrow transplant options and preferences in a sickle cell anemia cohort on chronic transfusions ⬇️

scientific article published on April 1, 2012

Brown recluse spider (Loxosceles reclusa) envenomation leading to acute hemolytic anemia in six adolescents

scientific article published on January 2010

Building capacity to reduce stroke in children with sickle cell anemia in the Dominican Republic: the SACRED trial

scientific article published on 01 November 2018

Case Report: β-thalassemia major on the East African coast

scientific article published on 13 July 2022

Characteristics of a rapid, point-of-care lateral flow immunoassay for the diagnosis of sickle cell disease

scientific article published on 26 November 2015

Chemical and functional analysis of generic hydroxyurea formulations

scientific article published in June 2008

Chlamydia pneumoniae and acute chest syndrome in patients with sickle cell disease

scientific article published on January 2003

Chromosome damage and repair in children with sickle cell anaemia and long-term hydroxycarbamide exposure

scientific article published on 4 May 2011

Chronic transfusion practice for children with sickle cell anaemia and stroke

scientific article

Chronic transfusion practices for prevention of primary stroke in children with sickle cell anemia and abnormal TCD velocities ⬇️

scientific article published on January 9, 2012

Clinical Features of β-Thalassemia and Sickle Cell Disease

scientific article published in January 2017

Clinical and hematologic benefits of partial splenectomy for congenital hemolytic anemias in children

scientific article published on 01 February 2003

Current Management of Sickle Cell Anemia ⬇️

scientific article published on August 1, 2013

Development of a pharmacokinetic-guided dose individualization strategy for hydroxyurea treatment in children with sickle cell anaemia

scientific article published on 28 November 2015

Diagnosis and management of chronic and refractory immune cytopenias in children, adolescents, and young adults

scientific article published on 01 June 2018

EXpanding Treatment for Existing Neurological Disease (EXTEND): An Open-Label Phase II Clinical Trial of Hydroxyurea Treatment in Sickle Cell Anemia.

scientific article published on 12 September 2016

Effect of hydroxyurea on growth in children with sickle cell anemia: results of the HUG-KIDS Study

scientific article published in February 2002

Effect of hydroxyurea treatment on renal function parameters: Results from the multi‐center placebo‐controlled BABY HUG clinical trial for infants with sickle cell anemia ⬇️

scientific article published on January 31, 2012

Effective screening leads to better outcomes in sickle cell disease

scientific article published on 14 February 2018

Effects of hydroxyurea treatment for patients with hemoglobin SC disease

scientific article

Electrochemical Determination of Hydroxyurea in a Complex Biological Matrix Using MoS<sub>2</sub>-Modified Electrodes and Chemometrics

scientific article published on 24 December 2020

Empowering newborn screening programs in African countries through establishment of an international collaborative effort

scientific article published on 15 May 2020

Epigenetic and molecular profiles of erythroid cells after hydroxyurea treatment in sickle cell anemia

scientific article published on 14 September 2011

Evidence gaps in the management of sickle cell disease: A summary of needed research

scientific article published on 17 February 2015

From infancy to adolescence: fifteen years of continuous treatment with hydroxyurea in sickle cell anemia

scientific article

Genetic Modifiers of White Blood Cell Count, Albuminuria and Glomerular Filtration Rate in Children with Sickle Cell Anemia

scientific article

Genetic mapping and exome sequencing identify 2 mutations associated with stroke protection in pediatric patients with sickle cell anemia ⬇️

scientific article published on February 19, 2013

Genetic modifiers of sickle cell anemia in the BABY HUG cohort: influence on laboratory and clinical phenotypes ⬇️

scientific article published on May 30, 2013

Genetic predictors for stroke in children with sickle cell anemia ⬇️

scientific article published on April 22, 2011

Genotoxicity associated with hydroxyurea exposure in infants with sickle cell anemia: Results from the BABY‐HUG phase III clinical trial ⬇️

scientific article published on October 19, 2011

Glomerular hyperfiltration and albuminuria in children with sickle cell anemia ⬇️

scientific article published on May 11, 2011

Hemodynamic responses to visual stimulation in children with sickle cell anemia

scientific article published on December 2011

Hemoglobin variants identified in the Uganda Sickle Surveillance Study

scientific article published on 22 November 2016

Hydroxycarbamide alters erythroid gene expression in children with sickle cell anaemia

scientific article published on 24 February 2012

Hydroxycarbamide in very young children with sickle-cell anaemia: a multicentre, randomised, controlled trial (BABY HUG).

scientific article

Hydroxycarbamide versus chronic transfusion for maintenance of transcranial doppler flow velocities in children with sickle cell anaemia-TCD With Transfusions Changing to Hydroxyurea (TWiTCH): a multicentre, open-label, phase 3, non-inferiority tria

scientific article published on 4 December 2015

Hydroxyurea Dose Escalation for Sickle Cell Anemia in Sub-Saharan Africa

scientific article published on 01 June 2020

Hydroxyurea Exposure in Lactation: a Pharmacokinetics Study (HELPS)

scientific article published on 11 March 2020

Hydroxyurea Pharmacokinetics in Pediatric Patients After Total Pancreatectomy With Islet Autotransplantation

scientific article published on 07 October 2020

Hydroxyurea Therapy for Children With Sickle Cell Anemia in Sub-Saharan Africa: Rationale and Design of the REACH Trial.

scientific article published on 14 August 2015

Hydroxyurea for Children with Sickle Cell Anemia in Sub-Saharan Africa

scientific article published on 10 January 2019

Hydroxyurea for children with sickle cell anemia: Prescribe it early and often

scientific article published on 30 April 2019

Hydroxyurea for children with sickle cell disease

scientific article published in April 2008

Hydroxyurea for sickle cell anemia: what have we learned and what questions still remain? ⬇️

scientific article published on May 1, 2011

Hydroxyurea therapy for management of secondary erythrocytosis in cyanotic congenital heart disease

scientific article published in August 2007

Hydroxyurea therapy for sickle cell anemia

scientific article published on 14 September 2015

Hydroxyurea therapy lowers transcranial Doppler flow velocities in children with sickle cell anemia

scientific article published on 11 April 2007

Hydroxyurea therapy of a murine model of sickle cell anemia inhibits the progression of pneumococcal disease by down-modulating E-selectin

scientific article

Hydroxyurea therapy requires HbF induction for clinical benefit in a sickle cell mouse model

scientific article

Hydroxyurea to lower TCD velocities and prevent primary stroke: the Uganda NOHARM sickle cell anemia cohort

scientific article published on 24 October 2019

Hydroxyurea treatment decreases glomerular hyperfiltration in children with sickle cell anemia ⬇️

scientific article published on December 17, 2012

Hydroxyurea: Analytical techniques and quantitative analysis

scientific article published on 8 August 2017

Identification of hemochromatosis gene polymorphisms in chronically transfused patients with sickle cell disease.

scientific article published in December 2003

IgA‐mediated autoimmune hemolytic anemia in an infant ⬇️

scientific article published on December 22, 2010

Immunologic effects of hydroxyurea in sickle cell anemia

scientific article

Impact of hydroxyurea on clinical events in the BABY HUG trial

scientific article

Interpretation of fetal hemoglobin only on newborn screening for hemoglobinopathy

scientific article published in August 2002

Kidney function of transfused children with sickle cell anemia: Baseline data from the TWiTCH study with comparison to non-transfused cohorts.

scientific article published on 25 July 2017

Knowledge gaps in reproductive and sexual health in girls and women with sickle cell disease

scientific article

Liver iron concentration measurements by MRI in chronically transfused children with sickle cell anemia: baseline results from the TWiTCH trial

scientific article

Long-term hydroxyurea therapy for infants with sickle cell anemia: the HUSOFT extension study

scientific article published in October 2005

Long‐term results using hydroxyurea/phlebotomy for reducing secondary stroke risk in children with sickle cell anemia and iron overload ⬇️

scientific article published on April 1, 2011

Magnetic resonance imaging/angiography and transcranial Doppler velocities in sickle cell anemia: results from the SWiTCH trial

scientific article

Malignancy in patients with sickle cell disease

scientific article published on December 2003

Management of sickle cell disease: summary of the 2014 evidence-based report by expert panel members

scientific article

Massive accidental overdose of hydroxyurea in a young child with sickle cell anemia ⬇️

scientific article published on July 8, 2011

Microarray analysis of liver gene expression in iron overloaded patients with sickle cell anemia and beta-thalassemia

scientific article

Model-based dosing with concentration feedback as an integral part of personalized hydroxycarbamide management

scientific article published on 17 April 2018

Neurocognitive development of young children with sickle cell disease through three years of age.

scientific article published in April 2002

Newborn Screening With Sickle Cell Point of Care: A Valuable Resource in Low-Income Settings

scientific article published on 17 September 2019

Novel Dose Escalation to Predict Treatment with Hydroxyurea (NDEPTH): A Randomized Controlled Trial of a Dose-Prediction Equation to Determine Maximum Tolerated Dose of Hydroxyurea in Pediatric Sickle Cell Disease

scientific article published on 30 May 2020

Novel Use of Hydroxyurea in an African Region With Malaria: Protocol for a Randomized Controlled Clinical Trial

scientific article published on 23 June 2016

Novel use Of Hydroxyurea in an African Region with Malaria (NOHARM): a trial for children with sickle cell anemia

scientific article

Organ iron accumulation in chronically transfused children with sickle cell anaemia: baseline results from the TWiTCH trial

scientific article

Organic anion transporting polypeptide 1B transporters modulate hydroxyurea pharmacokinetics

scientific article published on 28 August 2013

Pain and other non-neurological adverse events in children with sickle cell anemia and previous stroke who received hydroxyurea and phlebotomy or chronic transfusions and chelation: results from the SWiTCH clinical trial

scientific article

Partial splenectomy for children with congenital hemolytic anemia and massive splenomegaly

scientific article published in March 2008

Pelger-Huët anomaly in a child with 1q42.3-44 deletion

scientific article published in May 2006

Perceived benefits and risks of participation in a clinical trial for Ugandan children with sickle cell anemia

scientific article published on 28 May 2019

Pharmacokinetics, pharmacodynamics, and pharmacogenetics of hydroxyurea treatment for children with sickle cell anemia ⬇️

scientific article published on August 29, 2011

Pilot of the Chronic Disease Self-Management Program for Adolescents and Young Adults With Sickle Cell Disease

scientific article published on 25 October 2016

Practice guideline for pulmonary hypertension in sickle cell: direct evidence needed before universal adoption

Predictors of fetal hemoglobin response in children with sickle cell anemia receiving hydroxyurea therapy ⬇️

scientific article published on January 1, 2002

Preservation of spleen and brain function in children with sickle cell anemia treated with hydroxyurea

scientific article published in February 2008

Prevalence of inherited blood disorders and associations with malaria and anemia in Malawian children

scientific article published on 01 November 2018

Prevention of secondary stroke and resolution of transfusional iron overload in children with sickle cell anemia using hydroxyurea and phlebotomy

scientific article published in September 2004

R2* magnetic resonance imaging of the liver in patients with iron overload

scientific article published on 04 March 2009

RHD zygosity predicts degree of platelet response to anti-D immune globulin treatment in children with immune thrombocytopenia ⬇️

scientific article published on May 27, 2013

Realizing effectiveness across continents with hydroxyurea: Enrollment and baseline characteristics of the multicenter REACH study in Sub-Saharan Africa

scientific article published on 10 January 2018

Reply to iManage: A novel self-management app for sickle cell disease

scientific article published on 5 November 2016

Robust clinical and laboratory response to hydroxyurea using pharmacokinetically guided dosing for young children with sickle cell anemia

scientific article published on 12 June 2019

Sickle cell anemia in sub-Saharan Africa: advancing the clinical paradigm through partnerships and research.

scientific article

Sickle cell disease

scientific article published on 31 January 2017

Sickle cell screening in Europe: the time has come

scientific article published on 14 November 2018

Sickle cell screening in Uganda: High burden, human immunodeficiency virus comorbidity, and genetic modifiers

scientific article published on 16 May 2019

Sickle-cell disease: an ounce of prevention, a pound of cure

scientific article

Simultaneous acute splenic sequestration and transient aplastic crisis in children with sickle cell disease

scientific article

Stable-Isotope Dilution HPLC-Electrospray Ionization Tandem Mass Spectrometry Method for Quantifying Hydroxyurea in Dried Blood Samples

scientific article published on 30 September 2016

Stroke Avoidance for Children in REpública Dominicana (SACRED): Protocol for a Prospective Study of Stroke Risk and Hydroxyurea Treatment in Sickle Cell Anemia

scientific article

Stroke With Transfusions Changing to Hydroxyurea (SWiTCH) ⬇️

scientific article published on February 7, 2012

Stroke with transfusions changing to hydroxyurea (SWiTCH): A phase III randomized clinical trial for treatment of children with sickle cell anemia, stroke, and iron overload ⬇️

scientific article published on August 8, 2011

Subclinical parvovirus B19 infection in children with sickle cell anemia

scientific article

Surveillance for sickle cell disease, United Republic of Tanzania

scientific article published on 28 September 2020

Sustained long-term hematologic efficacy of hydroxyurea at maximum tolerated dose in children with sickle cell disease

scientific article published on 20 November 2003

The Clinical and Laboratory Spectrum of Hb C [β6(A3)Glu→Lys,GAG&gt;AAG] Disease ⬇️

scientific article published on January 1, 2013

The diagnostic dilemma of congenital unstable hemoglobinopathies ⬇️

scientific article published on December 15, 2010

The natural history of conditional transcranial Doppler flow velocities in children with sickle cell anaemia

scientific article published on 8 May 2008

The pediatric hydroxyurea phase III clinical trial (BABY HUG): challenges of study design

scientific article published on February 2010

The second century of sickle cell disease ⬇️

scientific article published on May 4, 2012

Therapeutic phlebotomy is safe in children with sickle cell anaemia and can be effective treatment for transfusional iron overload

scientific article

Thrombopoiesis: new ITP paradigm? ⬇️

scientific article published on July 7, 2011

Transcellular movement of hydroxyurea is mediated by specific solute carrier transporters ⬇️

scientific article published on January 21, 2011

Transfusional iron overload in children with sickle cell anemia on chronic transfusion therapy for secondary stroke prevention ⬇️

scientific article published on November 25, 2011

Translating sickle cell guidelines into practice for primary care providers with Project ECHO.

scientific article

UGT1A promoter polymorphisms influence bilirubin response to hydroxyurea therapy in sickle cell anemia

scientific article published in April 2003

UGT1A1 promoter polymorphisms and the development of hyperbilirubinemia and gallbladder disease in children with sickle cell anemia

scientific article published in October 2008

Urine concentrating ability in infants with sickle cell disease: baseline data from the phase III trial of hydroxyurea (BABY HUG).

scientific article

Whole exome sequencing identifies novel genes for fetal hemoglobin response to hydroxyurea in children with sickle cell anemia

scientific article

Whole-exome sequencing for RH genotyping and alloimmunization risk in children with sickle cell anemia

scientific article published on 03 August 2017

Your tired, your poor, your huddled masses

scientific article published on 01 May 2019

β-Thalassemia pathogenic variants in a cohort of children from the East African coast

scientific article published on 11 May 2020

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