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List of works by Robert O Opoka

963. Whole Blood Transcriptome Analysis Reveals Differences in Erythropoiesis and Neurologically Relevant Pathways Between Cerebral Malaria and Severe Malarial Anemia

scholarly article by Srinivas Nallandhighal et al published November 2018 in Open Forum Infectious Diseases

A Randomized Controlled Trial to Evaluate if Computerized Cognitive Rehabilitation Improves Neurocognition in Ugandan Children with HIV.

scientific article published on 4 April 2016

A mutation within the SH2 domain of slp-76 regulates the tissue distribution and cytokine production of iNKT cells in mice

scientific article

A pilot study of the neuropsychological benefits of computerized cognitive rehabilitation in Ugandan children with HIV.

scientific article

A year-long caregiver training program improves cognition in preschool Ugandan children with human immunodeficiency virus

scientific article published on 16 August 2013

A year-long caregiver training program to improve neurocognition in preschool Ugandan HIV-exposed children

scientific article published on May 2013

Acute Kidney Injury Is Common in Pediatric Severe Malaria and Is Associated With Increased Mortality

scientific article published on 26 February 2016

Adherence to clinical guidelines is associated with reduced inpatient mortality among children with severe anemia in Ugandan hospitals

scientific article published in PLoS ONE

Adjunctive therapy for cerebral malaria and other severe forms of Plasmodium falciparum malaria ⬇️

scientific article published on September 1, 2010

Admission EEG findings in diverse paediatric cerebral malaria populations predict outcomes.

scientific article

Anaemia and blood transfusion in African children presenting to hospital with severe febrile illness

scientific article

Association between coping strategies, social support, and depression and anxiety symptoms among rural Ugandan women living with HIV/AIDS.

scientific article

Association of caregiver quality of care with neurocognitive outcomes in HIV-affected children aged 2-5 years in Uganda

scientific article published on 17 February 2016

Authors' reply to Southall

scientific article published in the British Medical Journal

B-type natriuretic peptide and plasma hemoglobin levels following transfusion of shorter-storage versus longer-storage red blood cells: Results from the TOTAL randomized trial

scientific article published on 21 January 2016

Brain-derived Neurotrophic Factor Is Associated With Disease Severity and Clinical Outcome in Ugandan Children Admitted to Hospital With Severe Malaria

scientific article published on 25 October 2016

Caregivers' depressive symptoms and parent-report of child executive function among young children in Uganda

scientific article published on 30 January 2015

Cerebral Oximetry in Ugandan Children With Severe Anemia: Clinical Categories and Response to Transfusion

scientific article published on 8 August 2016

Cerebral malaria in children is associated with long-term cognitive impairment

scientific article published on 09 June 2008

Cerebral malaria is associated with long-term mental health disorders: a cross sectional survey of a long-term cohort

scientific article published on 31 March 2016

Cerebrospinal fluid cytokine levels and cognitive impairment in cerebral malaria.

scientific article

Cerebrospinal fluid kynurenine and kynurenic acid concentrations are associated with coma duration and long-term neurocognitive impairment in Ugandan children with cerebral malaria

scientific article published on 28 July 2017

Children's Oxygen Administration Strategies Trial (COAST):  A randomised controlled trial of high flow versus oxygen versus control in African children with severe pneumonia

scientific article published on 11 October 2017

Chitinase-3-like 1 is a biomarker of acute kidney injury and mortality in paediatric severe malaria

scientific article published on 15 February 2018

Clinical Comparison of Retinopathy-Positive and Retinopathy-Negative Cerebral Malaria

scientific article published on 30 January 2017

Co-trimoxazole or multivitamin multimineral supplement for post-discharge outcomes after severe anaemia in African children: a randomised controlled trial

scientific article published on 01 October 2019

Cognitive impairment after cerebral malaria in children: a prospective study

scientific article published on 15 January 2007

Comparison of iron status 28 d after provision of antimalarial treatment with iron therapy compared with antimalarial treatment alone in Ugandan children with severe malaria

scientific article published on 3 February 2016

Delaying Iron Therapy until 28 Days after Antimalarial Treatment Is Associated with Greater Iron Incorporation and Equivalent Hematologic Recovery after 56 Days in Children: A Randomized Controlled Trial.

scientific article published on 29 June 2016

Delaying the start of iron until 28 days after antimalarial treatment is associated with lower incidence of subsequent illness in children with malaria and iron deficiency

scientific article published on 30 August 2017

Differing Causes of Lactic Acidosis and Deep Breathing in Cerebral Malaria and Severe Malarial Anemia May Explain Differences in Acidosis-Related Mortality

scientific article

Effect of Caregiver Training on the Neurodevelopment of HIV-Exposed Uninfected Children and Caregiver Mental Health: A Ugandan Cluster-Randomized Controlled Trial

scientific article

Effect of Transfusion of Red Blood Cells With Longer vs Shorter Storage Duration on Elevated Blood Lactate Levels in Children With Severe Anemia: The TOTAL Randomized Clinical Trial

scientific article published on 05 December 2015

Elevated serum levels of IL-1ra in children with Plasmodium falciparum malaria are associated with increased severity of disease

scientific article published on 20 February 2008

Evidence of Endothelial Activation in Asymptomatic Plasmodium falciparum Parasitemia and Effect of Blood Group on Levels of von Willebrand Factor in Malaria

scientific article published on March 2012

Exploring experimental cerebral malaria pathogenesis through the characterisation of host-derived plasma microparticle protein content

scientific article published on 05 December 2016

Exploring mechanisms of excess mortality with early fluid resuscitation: insights from the FEAST trial

scientific article

FGF signaling is necessary for establishing gut tube domains along the anterior-posterior axis in vivo

scientific article published on 2 December 2005

Haematological quality and age of donor blood issued for paediatric transfusion to four hospitals in sub-Saharan Africa

scientific article

High Frequency of Blackwater Fever Among Children Presenting to Hospital With Severe Febrile Illnesses in Eastern Uganda

scientific article published on April 2017

High Postdischarge Morbidity in Ugandan Children With Severe Malarial Anemia or Cerebral Malaria

scientific article

High plasma erythropoietin levels are associated with prolonged coma duration and increased mortality in children with cerebral malaria

scientific article

High rate of inappropriate blood transfusions in the management of children with severe anemia in Ugandan hospitals

scholarly article by Robert O Opoka et al published 18 July 2018 in BMC Health Services Research

Host Biomarkers Are Associated With Response to Therapy and Long-Term Mortality in Pediatric Severe Malaria

scientific article published on 20 June 2016

Hydroxyurea Dose Escalation for Sickle Cell Anemia in Sub-Saharan Africa

scientific article published on 01 June 2020

Hypogammaglobulinemia in sub-Saharan Africa: a case report and review of the literature

scientific article

Identification of molecular markers that are expressed in discrete anterior-posterior domains of the endoderm from the gastrula stage to mid-gestation

scientific article published in July 2007

Immediate Transfusion in African Children with Uncomplicated Severe Anemia

scientific article published on 01 August 2019

Immediate neuropsychological and behavioral benefits of computerized cognitive rehabilitation in Ugandan pediatric cerebral malaria survivors

scientific article published on August 2009

Inhaled nitric oxide and cognition in pediatric severe malaria: A randomized double-blind placebo controlled trial

scientific article published on 25 January 2018

Inhaled nitric oxide as adjunctive therapy for severe malaria: a randomized controlled trial

scientific article

Inhaled nitric oxide for the adjunctive therapy of severe malaria: protocol for a randomized controlled trial

scientific article published on 13 July 2011

Inpatient mortality in children with clinically diagnosed malaria as compared with microscopically confirmed malaria

scientific article published on April 2008

Investigating arsenic susceptibility from a genetic perspective in Drosophila reveals a key role for glutathione synthetase

scientific article published on 08 September 2008

Lack of mortality in 22 children with sickle cell anemia and severe malarial anemia

scientific article published on 17 August 2017

Lactate clearance as a prognostic marker of mortality in severely ill febrile children in East Africa.

scientific article

Malaria illness mediated by anaemia lessens cognitive development in younger Ugandan children

scientific article published on 14 April 2016

Methemoglobin and nitric oxide therapy in Ugandan children hospitalized for febrile illness: results from a prospective cohort study and randomized double-blind placebo-controlled trial

scientific article

Mortality after fluid bolus in African children with severe infection

scientific article published on 26 May 2011

Mortality risk over time after early fluid resuscitation in African children

scientific article published on 27 November 2019

Neruodevelopmental Outcomes in Pre-School Children Living with HIV-1 Subtypes A and D in Uganda.

scientific article published on 9 May 2018

Neurocognitive domains affected by cerebral malaria and severe malarial anemia in children

scientific article published on 16 January 2015

Novel Use of Hydroxyurea in an African Region With Malaria: Protocol for a Randomized Controlled Clinical Trial

scientific article published on 23 June 2016

Novel use Of Hydroxyurea in an African Region with Malaria (NOHARM): a trial for children with sickle cell anemia

scientific article

Nutritional and Immunological Correlates of Memory and Neurocognitive Development Among HIV-Infected Children Living in Kayunga, Uganda

scientific article published on 20 November 2015

Obligations under global health partnerships in LMICs should be contractual

scientific article published in September 2017

Patients with nodding syndrome in Uganda improve with symptomatic treatment: a cross-sectional study

scientific article

Perceived benefits and risks of participation in a clinical trial for Ugandan children with sickle cell anemia

scientific article published on 28 May 2019

Perceptions of postgraduate trainees on the impact of objective structured clinical examinations on their study behavior and clinical practice

scientific article published on 3 June 2015

Performance of point-of-care diagnostics for glucose, lactate, and hemoglobin in the management of severe malaria in a resource-constrained hospital in Uganda

scientific article published on 03 March 2014

Plasmodium falciparum EPCR-binding PfEMP1 expression increases with malaria disease severity and is elevated in retinopathy negative cerebral malaria

scientific article published on 13 October 2017

Plasmodium falciparum Histidine-Rich Protein-2 Plasma Concentrations Are Higher in Retinopathy-Negative Cerebral Malaria Than in Severe Malarial Anemia

scientific article published on 22 July 2017

Predicting mortality in sick African children: the FEAST Paediatric Emergency Triage (PET) Score

scientific article published on 31 July 2015

Prospective validation of pediatric disease severity scores to predict mortality in Ugandan children presenting with malaria and non-malaria febrile illness

scientific article

Randomized controlled trial of caregiver training for HIV-infected child neurodevelopment and caregiver well being

scientific article published on 12 June 2017

Reliability of the Luganda version of the Child Behaviour Checklist in measuring behavioural problems after cerebral malaria

scientific article published on 8 December 2009

Response of fluctuating asymmetry to arsenic toxicity: support for the developmental selection hypothesis

scientific article published in January 2002

Serum angiopoietin-1 and -2 levels discriminate cerebral malaria from uncomplicated malaria and predict clinical outcome in African children

scientific article

Severe malarial anemia is associated with long-term neurocognitive impairment

scientific article

Slow Clearance of Plasmodium falciparum in Severe Pediatric Malaria, Uganda, 2011-2013.

scientific article published on July 2015

Socio-demographic correlates of depression and anxiety among female caregivers living with HIV in rural Uganda

scientific article published on 30 May 2016

Socioeconomic predictors of cognition in Ugandan children: implications for community interventions

scientific article

Solar-Powered Oxygen Delivery in Low-Resource Settings: A Randomized Clinical Noninferiority Trial

Sox17 and Sox4 differentially regulate beta-catenin/T-cell factor activity and proliferation of colon carcinoma cells

scientific article

TLR9 polymorphisms are associated with altered IFN-gamma levels in children with cerebral malaria

scientific article

The Collaborative Role of North American Departments of Pediatrics in Global Child Health

article

The endothelial protein C receptor rs867186-GG genotype is associated with increased soluble EPCR and could mediate protection against severe malaria

scientific article published on 03 June 2016

Thrombocytopenia May Mediate Disease Severity in Plasmodium falciparum Malaria Through Reduced Transforming Growth Factor Beta-1 Regulation of Proinflammatory and Anti-inflammatory Cytokines

scientific article

Toll-like receptor polymorphisms and cerebral malaria: TLR2 Δ22 polymorphism is associated with protection from cerebral malaria in a case control study ⬇️

scientific article published on February 15, 2012

Transfusion Volume for Children with Severe Anemia in Africa

scientific article published on 01 August 2019

Transfusion and Treatment of severe anaemia in African children (TRACT): a study protocol for a randomised controlled trial

scientific article

Use of a three-band HRP2/pLDH combination rapid diagnostic test increases diagnostic specificity for falciparum malaria in Ugandan children

scientific article published on February 2014

Use of pre-hospital medication in children presenting with malaria to the emergency unit of Mulago Hospital, Uganda: A descriptive study.

scientific article

Use of the Behavior Rating Inventory of Executive Function and Child Behavior Checklist in Ugandan Children with HIV or a History of Severe Malaria

scientific article published on May 2015

Vitamin D insufficiency is common in Ugandan children and is associated with severe malaria

scientific article

WHO guidelines on fluid resuscitation in children: missing the FEAST data

scientific article

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