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List of works by James Beeson

A malaria vaccine in children with HIV.

scientific article published on 6 July 2016

A novel approach to identifying patterns of human invasion-inhibitory antibodies guides the design of malaria vaccines incorporating polymorphic antigens

scientific article

A phase 1 trial of MSP2-C1, a blood-stage malaria vaccine containing 2 isoforms of MSP2 formulated with Montanide® ISA 720

scientific article (publication date: 2011)

A single point in protein trafficking by Plasmodium falciparum determines the expression of major antigens on the surface of infected erythrocytes targeted by human antibodies

scientific article published on 19 May 2016

A var gene promoter controls allelic exclusion of virulence genes in Plasmodium falciparum malaria

scientific article published on 28 December 2005

Acquired antibodies to merozoite antigens in children from Uganda with uncomplicated or severe Plasmodium falciparum malaria

scientific article published on 05 June 2013

Acquisition of Antibodies Against Endothelial Protein C Receptor-Binding Domains of Plasmodium falciparum Erythrocyte Membrane Protein 1 in Children with Severe Malaria

scholarly article by Janavi S Rambhatla et al published 26 October 2018 in Journal of Infectious Diseases

Acquisition of Functional Antibodies That Block the Binding of Erythrocyte-Binding Antigen 175 and Protection Against Plasmodium falciparum Malaria in Children

scientific article published on July 2015

Acquisition of antibodies against Plasmodium falciparum merozoites and malaria immunity in young children and the influence of age, force of infection, and magnitude of response

scientific article published on 24 November 2014

Acquisition of growth-inhibitory antibodies against blood-stage Plasmodium falciparum

scientific article

Acquisition, maintenance and adaptation of invasion inhibitory antibodies against Plasmodium falciparum invasion ligands involved in immune evasion ⬇️

scientific article

Age-dependent changes in circulating Tfh cells influence development of functional malaria antibodies in children

scientific article published in 2022

Analysis of structure and function of the giant protein Pf332 in Plasmodium falciparum

scientific article (publication date: 2009)

Antibodies to chondroitin sulfate A-binding infected erythrocytes: dynamics and protection during pregnancy in women receiving intermittent preventive treatment

scientific article published in May 2010

Antibodies to polymorphic invasion-inhibitory and non-Inhibitory epitopes of Plasmodium falciparum apical membrane antigen 1 in human malaria ⬇️

scientific article

Antibodies to reticulocyte binding protein-like homologue 4 inhibit invasion of Plasmodium falciparum into human erythrocytes ⬇️

scientific article

Antibodies to variant surface antigens of Plasmodium falciparum-infected erythrocytes and adhesion inhibitory antibodies are associated with placental malaria and have overlapping and distinct targets

scientific article published on 21 January 2004

Antibody Boosting and Longevity Following Tetanus Immunization During Pregnancy ⬇️

scientific article published on November 26, 2012

Antibody Responses to Plasmodium falciparum and Plasmodium vivax and Prospective Risk of Plasmodium spp. Infection Postpartum

scientific article

Antibody responses to Plasmodium falciparum and Plasmodium vivax blood-stage and sporozoite antigens in the postpartum period

scientific article published on 25 August 2016

Antibody to P. falciparum in pregnancy varies with intermittent preventive treatment regime and bed net use.

scientific article

Antibody-mediated growth inhibition of Plasmodium falciparum: relationship to age and protection from parasitemia in Kenyan children and adults

scientific article

Antigenic characterization of an intrinsically unstructured protein, Plasmodium falciparum merozoite surface protein 2.

scientific article

Antigenic differences and conservation among placental Plasmodium falciparum-infected erythrocytes and acquisition of variant-specific and cross-reactive antibodies

scientific article published on 30 January 2006

Association between malaria immunity and pregnancy outcomes among Malawian pregnant women receiving nutrient supplementation

scientific article

Association between naturally acquired antibodies to erythrocyte-binding antigens of Plasmodium falciparum and protection from malaria and high-density parasitemia

scientific article published in October 2010

Broad analysis reveals a consistent pattern of var gene transcription in Plasmodium falciparum repeatedly selected for a defined adhesion phenotype

scientific article published in May 2005

Cellular tumor necrosis factor, gamma interferon, and interleukin-6 responses as correlates of immunity and risk of clinical Plasmodium falciparum malaria in children from Papua New Guinea

scientific article published on 20 April 2009

Challenges and strategies for developing efficacious and long-lasting malaria vaccines

scientific article published on 01 January 2019

Characteristics of Plasmodium falciparum-infected-erythrocyte adhesion to chondroitin sulfate

scientific article published in June 2008

Characterization of VAR2CSA-deficient Plasmodium falciparum-infected erythrocytes selected for adhesion to the BeWo placental cell line

scientific article published on 26 March 2008

Clinical features and pathogenesis of severe malaria

scientific article

Combating low birth weight due to malaria infection in pregnancy.

scientific article

Complement in malaria immunity and vaccines

scientific article published on 26 September 2019

Complement receptor 1 is the host erythrocyte receptor for Plasmodium falciparum PfRh4 invasion ligand ⬇️

scientific article published on 20 September 2010

Conformational dynamics and antigenicity in the disordered malaria antigen merozoite surface protein 2

scientific article

Contrasting Patterns of Serologic and Functional Antibody Dynamics to Plasmodium falciparum Antigens in a Kenyan Birth Cohort

scientific article published on 9 December 2015

Correction: Overcoming Antigenic Diversity by Enhancing the Immunogenicity of Conserved Epitopes on the Malaria Vaccine Candidate Apical Membrane Antigen-1.

scientific article

Cross-reactive surface epitopes on chondroitin sulfate A-adherent Plasmodium falciparum-infected erythrocytes are associated with transcription of var2csa

scientific article

Declining Transmission and Immunity to Malaria and Emerging Artemisinin Resistance in Thailand: A Longitudinal Study

scientific article published on September 2017

Declining malaria transmission differentially impacts on the maintenance of humoral immunity to Plasmodium falciparum in children

scientific article published on 2 August 2017

Decreasing malaria prevalence and its potential consequences for immunity in pregnant women

scientific article published on 5 May 2014

Defining species-specific and conserved interactions of apical membrane protein 1 during erythrocyte invasion in malaria to inform multi-species vaccines

scientific article published in 2023

Defining the antigenic diversity of Plasmodium falciparum apical membrane antigen 1 and the requirements for a multi-allele vaccine against malaria

scientific article

Defining the timing of action of antimalarial drugs against Plasmodium falciparum

scientific article published on 14 January 2013

Designing malaria vaccines to circumvent antigen variability

scientific article published on 13 October 2015

Determinants of knowledge of critical danger signs, safe childbirth and immediate newborn care practices among auxiliary midwives: a cross sectional survey in Myanmar

scientific article published on 5 July 2017

Development and optimization of high-throughput methods to measure Plasmodium falciparum-specific growth inhibitory antibodies

scientific article

Development of fluorescent Plasmodium falciparum for in vitro growth inhibition assays

scientific article

Dichotomous miR expression and immune responses following primary blood-stage malaria

scientific article

Differences in affinity of monoclonal and naturally acquired polyclonal antibodies against Plasmodium falciparum merozoite antigens

scientific article published on 3 July 2015

Differing rates of antibody acquisition to merozoite antigens in malaria: implications for immunity and surveillance

scientific article published on 11 November 2016

Dihydroartemisinin-piperaquine for intermittent preventive treatment of malaria during pregnancy and risk of malaria in early childhood: A randomized controlled trial

scientific article published on 17 July 2018

Discovery of GAMA, a Plasmodium falciparum merozoite micronemal protein, as a novel blood-stage vaccine candidate antigen

scientific article published on 6 September 2011

Does malaria affect placental development? Evidence from in vitro models

scientific article

Effect of nutrient supplementation on the acquisition of humoral immunity to Plasmodium falciparum in young Malawian children

scientific article published on 7 February 2018

Effectiveness of repellent delivered through village health volunteers on malaria incidence in villages in South-East Myanmar: a stepped-wedge cluster-randomised controlled trial protocol

article

Erythrocyte-binding antigens of Plasmodium falciparum are targets of human inhibitory antibodies and function to evade naturally acquired immunity

scientific article published on 17 June 2013

Estimating the burden of global mortality in children aged <5 years by pathogen-specific causes

scientific article published in June 2008

Evaluating antibody functional activity and strain-specificity of vaccine candidates for malaria in pregnancy using in vitro phagocytosis assays

scientific article published on 29 January 2018

Evaluating specific adhesion of Plasmodium falciparum-infected erythrocytes to immobilised hyaluronic acid with comparison to binding of mammalian cells

scientific article published in September 2002

Evaluation of the antigenic diversity of placenta-binding Plasmodium falciparum variants and the antibody repertoire among pregnant women

scientific article

Evaluation of the effectiveness of topical repellent distributed by village health volunteer networks against Plasmodium spp. infection in Myanmar: A stepped-wedge cluster randomised trial

scientific article published on 20 August 2020

Evidence that the erythrocyte invasion ligand PfRh2 is a target of protective immunity against Plasmodium falciparum malaria

scientific article published on 20 October 2010

Expanding the paradigms of placental malaria

scientific article published in April 2002

Exported proteins required for virulence and rigidity of Plasmodium falciparum-infected human erythrocytes

scientific article (publication date: 11 July 2008)

Factors influencing the induction of high affinity antibodies to Plasmodium falciparum merozoite antigens and how affinity changes over time.

scientific article published on 13 June 2018

Functional Antibodies and Protection against Blood-stage Malaria

scientific article

Functional conservation of the AMA1 host-cell invasion ligand between P. falciparum and P. vivax: a novel platform to accelerate vaccine and drug development

scientific article

High affinity antibodies to Plasmodium falciparum merozoite antigens are associated with protection from malaria

scientific article

Host age and expression of genes involved in red blood cell invasion in Plasmodium falciparum field isolates ⬇️

scientific article

Host immunity to Plasmodium falciparum and the assessment of emerging artemisinin resistance in a multinational cohort

scientific article published on 13 March 2017

Human antibodies activate complement against Plasmodium falciparum sporozoites, and are associated with protection against malaria in children

scientific article published on 30 April 2018

Human antibodies fix complement to inhibit Plasmodium falciparum invasion of erythrocytes and are associated with protection against malaria ⬇️

scientific article

Identification and prioritization of merozoite antigens as targets of protective human immunity to Plasmodium falciparum malaria for vaccine and biomarker development

scientific article published on 17 June 2013

Identification of Heparin Modifications and Polysaccharide Inhibitors of Plasmodium falciparum Merozoite Invasion That Have Potential for Novel Drug Development ⬇️

scientific article published on 11 September 2017

Identifying Immune Correlates of Protection Against Plasmodium falciparum Through a Novel Approach to Account for Heterogeneity in Malaria Exposure

scientific article published in February 2018

IgG against Plasmodium falciparum variant surface antigens and growth inhibitory antibodies in Mozambican children receiving intermittent preventive treatment with sulfadoxine-pyrimethamine

scientific article published on 25 December 2010

IgM in human immunity to Plasmodium falciparum malaria

scientific article published on 25 September 2019

Immunity to malaria in an era of declining malaria transmission

scientific article

Immunization with VAR2CSA-DBL5 recombinant protein elicits broadly cross-reactive antibodies to placental Plasmodium falciparum-infected erythrocytes

scientific article

Immunoglobulin G subclass-specific responses against Plasmodium falciparum merozoite antigens are associated with control of parasitemia and protection from symptomatic illness

scientific article published on 12 January 2009

Impaired placental autophagy in placental malaria

scientific article published on 10 November 2017

Impairment of humoral immunity to Plasmodium falciparum malaria in pregnancy by HIV infection

scientific article published in June 2004

Implications of the licensure of a partially efficacious malaria vaccine on evaluating second-generation vaccines

scientific article

Infectivity of Plasmodium falciparum in Malaria-Naive Individuals Is Related to Knob Expression and Cytoadherence of the Parasite

scientific article published on 05 July 2016

Inhibition of Binding of Malaria-Infected Erythrocytes by a Tetradecasaccharide Fraction from Chondroitin Sulfate A ⬇️

scientific article published on July 1, 1998

Inhibition of placental mTOR signaling provides a link between placental malaria and reduced birthweight

scientific article

Insights into the Immunological Properties of Intrinsically Disordered Malaria Proteins Using Proteome Scale Predictions.

scientific article

Interactions with heparin-like molecules during erythrocyte invasion by Plasmodium falciparum merozoites

scientific article published on 10 March 2010

Intermittent preventive treatment for malaria in Papua New Guinean infants exposed to Plasmodium falciparum and P. vivax: a randomized controlled trial

scientific article published in 2012

Intermittent preventive treatment to reduce the burden of malaria in children: new evidence on integration and delivery

scientific article

Iron deficiency during pregnancy is associated with a reduced risk of adverse birth outcomes in a malaria-endemic area in a longitudinal cohort study

scholarly article by Freya Fowkes et al published 20 September 2018 in BMC Medicine

Isolation of viable Plasmodium falciparum merozoites to define erythrocyte invasion events and advance vaccine and drug development ⬇️

scientific article

Limited antigenic diversity of Plasmodium falciparum apical membrane antigen 1 supports the development of effective multi-allele vaccines

scientific article

Macrolides rapidly inhibit red blood cell invasion by the human malaria parasite, Plasmodium falciparum ⬇️

scientific article

Malaria and Age Variably but Critically Control Hepcidin Throughout Childhood in Kenya

scientific article

Malaria eradication and elimination: views on how to translate a vision into reality

scientific article published on 25 July 2015

Malaria in pregnancy and the endemicity spectrum: what can we learn?

scientific article published in September 2004

Malaria parasite signal peptide peptidase is an ER-resident protease required for growth but not for invasion

scientific article (publication date: November 2012)

Malaria vaccine candidates displayed on novel virus-like particles are immunogenic and induce transmission-blocking activity

scientific article published on 10 September 2019

Maternal-foetal transfer of Plasmodium falciparum and Plasmodium vivax antibodies in a low transmission setting

scientific article published on 10 February 2016

Maximizing antimalarial efficacy and the importance of dosing strategies

scientific article published on 9 May 2015

Merozoite Antigens of Plasmodium falciparum Elicit Strain-Transcending Opsonizing Immunity

scientific article published on 16 May 2016

Merozoite surface proteins in red blood cell invasion, immunity and vaccines against malaria

scientific article

Minimal association of common red blood cell polymorphisms with Plasmodium falciparum infection and uncomplicated malaria in Papua New Guinean school children

scientific article

Multiple morbidities in pregnancy: Time for research, innovation, and action

article

New approaches to studying Plasmodium falciparum merozoite invasion and insights into invasion biology

scientific article published on 05 December 2012

New insights into acquisition, boosting, and longevity of immunity to malaria in pregnant women

scientific article

Novel serologic biomarkers provide accurate estimates of recent Plasmodium falciparum exposure for individuals and communities

scientific article

Opsonic phagocytosis of Plasmodium falciparum merozoites: mechanism in human immunity and a correlate of protection against malaria

scientific article

Overcoming antigenic diversity by enhancing the immunogenicity of conserved epitopes on the malaria vaccine candidate apical membrane antigen-1.

scientific article

P. falciparum infection and maternofetal antibody transfer in malaria-endemic settings of varying transmission

scientific article published on 13 October 2017

PTEX is an essential nexus for protein export in malaria parasites

scientific article (publication date: 31 July 2014)

Patterns of protective associations differ for antibodies to P.falciparum-infected erythrocytes and merozoites in immunity against malaria in children.

scientific article

Perspectives: The missing pieces

scientific article published on 25 April 2012

PfEMP1 as a target of human immunity and a vaccine candidate against malaria

scientific article published in February 2013

PfRH5 as a candidate vaccine for Plasmodium falciparum malaria

scientific article published on 19 February 2015

Phenotypes of Plasmodium falciparum from the peripheral blood of pregnant women

scientific article published in March 2004

Placental malaria induces variant-specific antibodies of the cytophilic subtypes immunoglobulin G1 (IgG1) and IgG3 that correlate with adhesion inhibitory activity

scientific article

Placental malaria-associated inflammation disturbs the insulin-like growth factor axis of fetal growth regulation

scientific article

Plasmodium falciparum-infected erythrocytes demonstrate dual specificity for adhesion to hyaluronic acid and chondroitin sulfate A and have distinct adhesive properties

scientific article published on 6 January 2004

Plasmodium vivax adherence to placental glycosaminoglycans

scientific article

Plasmodium vivax malaria: challenges in diagnosis, treatment and elimination

scientific article published on May 2015

Platelet factor 4 and Duffy antigen required for platelet killing of Plasmodium falciparum

scientific article

Polymorphic and conserved targets of antibodies against Plasmodium falciparum during pregnancy

scientific article published in May 2008

Prevention of postpartum haemorrhage by community-based auxiliary midwives in hard-to-reach areas of Myanmar: a qualitative inquiry into acceptability and feasibility of task shifting

scientific article

Promising functional readouts of immunity in a blood-stage malaria vaccine trial

scientific article

Proteome-wide mapping of immune features onto Plasmodium protein three-dimensional structures.

scientific article

Quantifying the importance of MSP1-19 as a target of growth-inhibitory and protective antibodies against Plasmodium falciparum in humans

scientific article

Recent insights into humoral and cellular immune responses against malaria

scientific article published on 08 October 2008

Reply to Eisenhut

scientific article

Research priorities for the development and implementation of serological tools for malaria surveillance

scientific article

Reticulocyte and erythrocyte binding-like proteins function cooperatively in invasion of human erythrocytes by malaria parasites

scientific article

Reticulocyte-binding protein homologue 5 - an essential adhesin involved in invasion of human erythrocytes by Plasmodium falciparum

scientific article published on 25 October 2008

Selective accumulation of mature asexual stages of Plasmodium falciparum-infected erythrocytes in the placenta

scientific article

Sequential processing of merozoite surface proteins during and after erythrocyte invasion by Plasmodium falciparum ⬇️

scientific article

Serum lipoproteins promote efficient presentation of the malaria virulence protein PfEMP1 at the erythrocyte surface

scientific article

Sir2 paralogues cooperate to regulate virulence genes and antigenic variation in Plasmodium falciparum

scientific article (publication date: 14 April 2009)

Skeleton-binding protein 1 functions at the parasitophorous vacuole membrane to traffic PfEMP1 to the Plasmodium falciparum-infected erythrocyte surface

scientific article published on 5 October 2006

Strain-specific duffy binding protein antibodies correlate with protection against infection with homologous compared to heterologous plasmodium vivax strains in Papua New Guinean children

scientific article published on 29 June 2009

Strain-transcending immune response generated by chimeras of the malaria vaccine candidate merozoite surface protein 2.

scientific article published on 11 February 2016

Strengthening routine immunization in Papua New Guinea: a cross-sectional provincial assessment of front-line services

scientific article published on 23 January 2020

Structural basis for binding of Plasmodium falciparum erythrocyte membrane protein 1 to chondroitin sulfate and placental tissue and the influence of protein polymorphisms on binding specificity

scientific article published on 11 June 2007

Structure-Activity Studies of β-Hairpin Peptide Inhibitors of the Plasmodium falciparum AMA1-RON2 Interaction

scientific article

Subclass responses and their half-lives for antibodies against EBA175 and PfRh2 in naturally acquired immunity against Plasmodium falciparum malaria

scientific article

Super-resolution dissection of coordinated events during malaria parasite invasion of the human erythrocyte

scientific article published in January 2011

Surface antigens of Plasmodium falciparum-infected erythrocytes as immune targets and malaria vaccine candidates

scientific article

Targets of antibodies against Plasmodium falciparum-infected erythrocytes in malaria immunity

scientific article

Targets of protective antibodies to malaria during pregnancy

scientific article

The Plasmodium falciparum erythrocyte invasion ligand Pfrh4 as a target of functional and protective human antibodies against malaria. ⬇️

scientific article

The association between naturally acquired IgG subclass specific antibodies to the PfRH5 invasion complex and protection from Plasmodium falciparum malaria ⬇️

scientific article published on 08 September 2016

The complement system contributes to functional antibody-mediated responses induced by immunization with Plasmodium falciparum malaria sporozoites.

scientific article published on 7 May 2018

The exported chaperone Hsp70-x supports virulence functions for Plasmodium falciparum blood stage parasites

scientific article published on 21 July 2017

The future for blood-stage vaccines against malaria

scientific article published on 05 May 2009

The global threat of Zika virus to pregnancy: epidemiology, clinical perspectives, mechanisms, and impact

scientific article

The impact of early life exposure to Plasmodium falciparum on the development of naturally acquired immunity to malaria in young Malawian children

article

The impact of lipid-based nutrient supplementation on anti-malarial antibodies in pregnant women in a randomized controlled trial

scientific article published on 10 May 2015

The potential benefit of scaling up malaria prevention to reduce low birth weight in Africa

scientific article

The potential of task shifting selected maternal interventions to auxiliary midwives in Myanmar: a mixed-method study

scientific article published on 3 January 2018

The relationship between anti-merozoite antibodies and incidence of Plasmodium falciparum malaria: A systematic review and meta-analysis

scientific article

The structural motif in chondroitin sulfate for adhesion of Plasmodium falciparum-infected erythrocytes comprises disaccharide units of 4-O-sulfated and non-sulfated N-acetylgalactosamine linked to glucuronic acid

scientific article

Towards a vaccine against Plasmodium vivax malaria

scientific article published in December 2007

Truncation of Plasmodium berghei merozoite surface protein 8 does not affect in vivo blood-stage development

scientific article

Use of immunodampening to overcome diversity in the malarial vaccine candidate apical membrane antigen 1.

scientific article

Using an improved phagocytosis assay to evaluate the effect of HIV on specific antibodies to pregnancy-associated malaria

scientific article

Variation in use of erythrocyte invasion pathways by Plasmodium falciparum mediates evasion of human inhibitory antibodies ⬇️

scientific article

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