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List of works by Christina Spry

A class of pantothenic acid analogs inhibits Plasmodium falciparum pantothenate kinase and represses the proliferation of malaria parasites

scientific article

A miniaturized assay for measuring small molecule phosphorylation in the presence of complex matrices

scientific article published on 12 December 2013

Antiplasmodial Mode of Action of Pantothenamides: Pantothenate Kinase Serves as a Metabolic Activator Not as a Target

scientific article published on 24 April 2017

Coenzyme A biosynthesis: an antimicrobial drug target

scientific article published on January 2008

Exploiting the coenzyme A biosynthesis pathway for the identification of new antimalarial agents: the case for pantothenamides

scientific article

Feedback inhibition of pantothenate kinase regulates pantothenol uptake by the malaria parasite

scientific article published on 20 June 2007

Inhibiting Mycobacterium tuberculosis CoaBC by targeting an allosteric site

scientific article published on 08 January 2021

Mutations in the pantothenate kinase of Plasmodium falciparum confer diverse sensitivity profiles to antiplasmodial pantothenate analogues

scientific article published on 3 April 2018

Pantothenamides are potent, on-target inhibitors of Plasmodium falciparum growth when serum pantetheinase is inactivated

scientific article

Structural insights into Escherichia coli phosphopantothenoylcysteine synthetase by native ion mobility-mass spectrometry

scientific article published on 01 November 2019

Structural modification of pantothenamides counteracts degradation by pantetheinase and improves antiplasmodial activity

scientific article

Structure-activity analysis of CJ-15,801 analogues that interact with Plasmodium falciparum pantothenate kinase and inhibit parasite proliferation

scientific article published on 25 August 2017

Structure-activity relationships of antiplasmodial pantothenamide analogs reveal a new way by which triazoles mimic amide bonds

scientific article published on 29 November 2018

The human malaria parasite Plasmodium falciparum is not dependent on host coenzyme A biosynthesis

scientific article published on 07 July 2009

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