List of works - Jürgen Bosch

A BAC Transgene Expressing Human CFTR under Control of Its Regulatory Elements Rescues Cftr Knockout Mice

scientific article published on 14 August 2019

Aldolase provides an unusual binding site for thrombospondin-related anonymous protein in the invasion machinery of the malaria parasite

scientific article

Autophagy in Plasmodium, a multifunctional pathway?

scientific article published on 20 August 2013

Binding of aldolase and glyceraldehyde-3-phosphate dehydrogenase to the cytoplasmic tails of Plasmodium falciparum merozoite duffy binding-like and reticulocyte homology ligands

scientific article

Characterization and Structural Insights into Selective E1-E2 Interactions in the Human and Plasmodium falciparum SUMO Conjugation Systems

scientific article published on 23 December 2015

Characterization of the ATG8-conjugation system in 2 Plasmodium species with special focus on the liver stage: possible linkage between the apicoplastic and autophagic systems?

scientific article

Chromobacterium spp. mediate their anti-Plasmodium activity through secretion of the histone deacetylase inhibitor romidepsin.

scientific article published on 18 April 2018

Crystal structure of GAP50, the anchor of the invasion machinery in the inner membrane complex of Plasmodium falciparum ⬇️

scientific article

Crystal structure of glyceraldehyde-3-phosphate dehydrogenase from Plasmodium falciparum at 2.25 A resolution reveals intriguing extra electron density in the active site.

scientific article

Cyclic compression increases F508 Del CFTR expression in ciliated human airway epithelium

scientific article published on 22 May 2019

DXP synthase-catalyzed C-N bond formation: nitroso substrate specificity studies guide selective inhibitor design.

scientific article published on 03 July 2013

Development of a multifunctional tool for drug screening against plasmodial protein-protein interactions via surface plasmon resonance

scientific article published on October 2013

Discovery of Plasmodium (M)TRAP-Aldolase Interaction Stabilizers Interfering with Sporozoite Motility and Invasion.

scientific article published on 7 February 2018

Fragment-based cocktail crystallography by the medical structural genomics of pathogenic protozoa consortium

scientific article

Identification of Biochemically Distinct Properties of the Small Ubiquitin-related Modifier (SUMO) Conjugation Pathway in Plasmodium falciparum

scientific article

Identification of Novel Ezrin Inhibitors Targeting Metastatic Osteosarcoma by Screening Open Access Malaria Box.

scientific article

Identification of an Atg8-Atg3 protein-protein interaction inhibitor from the medicines for Malaria Venture Malaria Box active in blood and liver stage Plasmodium falciparum parasites

scientific article (publication date: 12 June 2014)

Immunization against a merozoite sheddase promotes multiple invasion of red blood cells and attenuates Plasmodium infection in mice.

scientific article

Microfluidic assessment of red blood cell mediated microvascular occlusion

scientific article published on 19 May 2020

PPI inhibitor and stabilizer development in human diseases.

scientific article published in June 2017

Purification, crystallization, and preliminary X-ray diffraction analysis of the Tricorn protease hexamer from Thermoplasma acidophilum

scientific article published on 01 April 2001

Structural and mechanistic insights into the function of the unconventional class XIV myosin MyoA from

article published in the Proceedings of the National Academy of Sciences of the United States of America

Structural characterization and inhibition of the Plasmodium Atg8–Atg3 interaction

scientific article

Structure of Toxoplasma gondii fructose-1,6-bisphosphate aldolase.

scientific article

Structure of a ribulose 5-phosphate 3-epimerase from Plasmodium falciparum

scientific article

Structure of the MTIP-MyoA complex, a key component of the malaria parasite invasion motor ⬇️

scholarly article

Structure-based drug design, synthesis and biological assays of P. falciparum Atg3-Atg8 protein-protein interaction inhibitors.

scientific article published on 30 January 2018

The 1.75 Å resolution structure of fission protein Fis1 fromSaccharomyces cerevisiaereveals elusive interactions of the autoinhibitory domain

scientific article

The apicomplexan glideosome and adhesins - Structures and function

scientific article published on 09 March 2015

Using Fragment Cocktail Crystallography To Assist Inhibitor Design ofTrypanosoma bruceiNucleoside 2-Deoxyribosyltransferase†

scientific article published in October 2006

Virtual Screening and Experimental Validation Identify Novel Inhibitors of the Plasmodium falciparum Atg8-Atg3 Protein-Protein Interaction.

scientific article published on 8 January 2016

List of works by Jürgen Bosch

A BAC Transgene Expressing Human CFTR under Control of Its Regulatory Elements Rescues Cftr Knockout Mice

Aldolase provides an unusual binding site for thrombospondin-related anonymous protein in the invasion machinery of the malaria parasite

Autophagy in Plasmodium, a multifunctional pathway?

Binding of aldolase and glyceraldehyde-3-phosphate dehydrogenase to the cytoplasmic tails of Plasmodium falciparum merozoite duffy binding-like and reticulocyte homology ligands

Characterization and Structural Insights into Selective E1-E2 Interactions in the Human and Plasmodium falciparum SUMO Conjugation Systems

Characterization of the ATG8-conjugation system in 2 Plasmodium species with special focus on the liver stage: possible linkage between the apicoplastic and autophagic systems?

Chromobacterium spp. mediate their anti-Plasmodium activity through secretion of the histone deacetylase inhibitor romidepsin.

Crystal structure of GAP50, the anchor of the invasion machinery in the inner membrane complex of Plasmodium falciparum ⬇️

Crystal structure of glyceraldehyde-3-phosphate dehydrogenase from Plasmodium falciparum at 2.25 A resolution reveals intriguing extra electron density in the active site.

Cyclic compression increases F508 Del CFTR expression in ciliated human airway epithelium

DXP synthase-catalyzed C-N bond formation: nitroso substrate specificity studies guide selective inhibitor design.

Development of a multifunctional tool for drug screening against plasmodial protein-protein interactions via surface plasmon resonance

Discovery of Plasmodium (M)TRAP-Aldolase Interaction Stabilizers Interfering with Sporozoite Motility and Invasion.

Fragment-based cocktail crystallography by the medical structural genomics of pathogenic protozoa consortium

Identification of Biochemically Distinct Properties of the Small Ubiquitin-related Modifier (SUMO) Conjugation Pathway in Plasmodium falciparum

Identification of Novel Ezrin Inhibitors Targeting Metastatic Osteosarcoma by Screening Open Access Malaria Box.

Identification of an Atg8-Atg3 protein-protein interaction inhibitor from the medicines for Malaria Venture Malaria Box active in blood and liver stage Plasmodium falciparum parasites

Immunization against a merozoite sheddase promotes multiple invasion of red blood cells and attenuates Plasmodium infection in mice.

Microfluidic assessment of red blood cell mediated microvascular occlusion

PPI inhibitor and stabilizer development in human diseases.

Purification, crystallization, and preliminary X-ray diffraction analysis of the Tricorn protease hexamer from Thermoplasma acidophilum

Structural and mechanistic insights into the function of the unconventional class XIV myosin MyoA from

Structural characterization and inhibition of the Plasmodium Atg8–Atg3 interaction

Structure of Toxoplasma gondii fructose-1,6-bisphosphate aldolase.

Structure of a ribulose 5-phosphate 3-epimerase from Plasmodium falciparum

Structure of the MTIP-MyoA complex, a key component of the malaria parasite invasion motor ⬇️

Structure-based drug design, synthesis and biological assays of P. falciparum Atg3-Atg8 protein-protein interaction inhibitors.

The 1.75 Å resolution structure of fission protein Fis1 fromSaccharomyces cerevisiaereveals elusive interactions of the autoinhibitory domain

The apicomplexan glideosome and adhesins - Structures and function

Using Fragment Cocktail Crystallography To Assist Inhibitor Design ofTrypanosoma bruceiNucleoside 2-Deoxyribosyltransferase†

Virtual Screening and Experimental Validation Identify Novel Inhibitors of the Plasmodium falciparum Atg8-Atg3 Protein-Protein Interaction.