List of works by Jacques Galipeau

A CCL2-Based Fusokine as a Novel Biopharmaceutical for the Treatment of CCR2-Driven Autoimmune Diseases

scientific article published on January 1, 2010

A Dendritic Cell Population Generated by a Fusion of GM-CSF and IL-21 Induces Tumor-Antigen–Specific Immunity ⬇️

scientific article published on November 12, 2010

A GMCSF and IL-15 fusokine leads to paradoxical immunosuppression in vivo via asymmetrical JAK/STAT signaling through the IL-15 receptor complex

scientific article published on 2 November 2006

A GMCSF and IL7 fusion cytokine leads to functional thymic-dependent T-cell regeneration in age-associated immune deficiency

scientific article published on 8 May 2015

A MCP1 fusokine with CCR2-specific tumoricidal activity

scientific article

A fusion cytokine coupling GMCSF to IL9 induces heterologous receptor clustering and STAT1 hyperactivation through JAK2 promiscuity ⬇️

scientific article

A fusion of GMCSF and IL-21 initiates hypersignaling through the IL-21Ralpha chain with immune activating and tumoricidal effects in vivo

scientific article

A granulocyte-macrophage colony-stimulating factor and interleukin-15 fusokine induces a regulatory B cell population with immune suppressive properties.

scientific article

A novel platelet lysate hydrogel for endothelial cell and mesenchymal stem cell-directed neovascularization.

scientific article

A self-inactivating retrovector incorporating the IL-2 promoter for activation-induced transgene expression in genetically engineered T-cells

scientific article published on 21 November 2006

Actin cytoskeletal disruption following cryopreservation alters the biodistribution of human mesenchymal stromal cells in vivo

scientific article

Adoptive transfer of IL-10+ regulatory B cells decreases myeloid-derived macrophages in the central nervous system in a transgenic amyotrophic lateral sclerosis model

scientific article published on 8 January 2018

Adoptive transfer of mesenchymal stromal cells accelerates intestinal epithelium recovery of irradiated mice in an interleukin-6-dependent manner

scientific article published on 10 May 2012

Airway delivery of mesenchymal stem cells prevents arrested alveolar growth in neonatal lung injury in rats

scientific article published on 27 August 2009

Allogeneic marrow stromal cells are immune rejected by MHC class I- and class II-mismatched recipient mice

scientific article published on 23 August 2005

Allogeneic mesenchymal stem cells for treatment of experimental autoimmune encephalomyelitis

scientific article

An engineered GM-CSF-CCL2 fusokine is a potent inhibitor of CCR2-driven inflammation as demonstrated in a murine model of inflammatory arthritis

scientific article published on 10 July 2009

Angiostatin inhibits monocyte/macrophage migration via disruption of actin cytoskeleton.

scientific article published on 10 July 2007

Aryl Hydrocarbon Receptor in Mesenchymal Stromal Cells: New Frontiers in AhR Biology

scientific article published on 16 October 2020

Author Correction: Factors of the bone marrow microniche that support human plasma cell survival and immunoglobulin secretion

scientific article published in Nature Communications

Autologous Mesenchymal Stromal Cells Prevent Transfusion-elicited Sensitization and Upregulate Transitional and Regulatory B Cells

Autologous bone marrow stromal cells genetically engineered to secrete an igf-I receptor decoy prevent the growth of liver metastases

scientific article

B cells for cancer immunotherapy

scientific article published on November 2014

B effector cells activated by a chimeric protein consisting of IL-2 and the ectodomain of TGF-β receptor II induce potent antitumor immunity

scientific article published on 12 January 2012

BCL2-BH4 antagonist BDA-366 suppresses human myeloma growth

scientific article published on 31 March 2016

Blood B Cell and Regulatory Subset Content in Multiple Sclerosis Patients

scientific article published on May 2015

Bone Marrow Mesenchymal Stromal Cells from Patients with Acute and Chronic Graft-versus-Host Disease Deploy Normal Phenotype, Differentiation Plasticity, and Immune-Suppressive Activity

scientific article published on 3 February 2015

Bone Marrow-Derived Mesenchymal Stromal Cells from Patients with Sickle Cell Disease Display Intact Functionality

scientific article

Bone marrow mesenchymal stromal cell therapy for external urethral sphincter restoration in a rat model of stress urinary incontinence.

scientific article published on 2 November 2010

Bone marrow mesenchymal stromal cells of patients with myeloproliferative disorders do not carry the JAK2-V617F mutation.

scientific article

CCL2 and CXCL12 Derived from Mesenchymal Stromal Cells Cooperatively Polarize IL-10+ Tissue Macrophages to Mitigate Gut Injury

scientific article published on 01 February 2020

CD34 expression on murine marrow-derived mesenchymal stromal cells: impact on neovascularization

scientific article published on 26 November 2007

Catalyzing umbilical cord blood research in Canada: a survey of current needs and practices of principal investigators

scientific article published on 01 January 2009

Challenges for mesenchymal stromal cell therapies

scientific article published on 01 February 2019

Challenges in animal modelling of mesenchymal stromal cell therapy for inflammatory bowel disease

scientific article

Characterization of Gaucher disease bone marrow mesenchymal stromal cells reveals an altered inflammatory secretome

scientific article

Concise review: engineering the fusion of cytokines for the modulation of immune cellular responses in cancer and autoimmune disorders

scientific article

Connexin over-expression differentially suppresses glioma growth and contributes to the bystander effect following HSV-thymidine kinase gene therapy

scientific article published in January 2006

Cooperation of matrix metalloproteinases with the RhoA/Rho kinase and mitogen-activated protein kinase kinase-1/extracellular signal-regulated kinase signaling pathways is required for the sphingosine-1-phosphate-induced mobilization of marrow-deriv

scientific article published on 24 August 2006

Coupling erythropoietin secretion to mesenchymal stromal cells enhances their regenerative properties

scientific article published on 8 April 2008

Cryopreserved Mesenchymal Stromal Cells Are Susceptible to T-Cell Mediated Apoptosis Which Is Partly Rescued by IFNγ Licensing.

scientific article published on 14 June 2016

Cryopreserved mesenchymal stromal cells display impaired immunosuppressive properties as a result of heat-shock response and impaired interferon-γ licensing

scientific article

Cytokine modulation of TLR expression and activation in mesenchymal stromal cells leads to a proinflammatory phenotype.

scientific article published in June 2009

Death and inflammation following somatic cell transplantation

scientific article published on May 2011

Design and fabrication of 3D porous scaffolds to facilitate cell-based gene therapy

scientific article

Development and function of innate polyclonal TCRalphabeta+ CD8+ thymocytes.

scientific article

Endothelial NO-Synthase Gene-Enhanced Progenitor Cell Therapy for Pulmonary Arterial Hypertension: The PHACeT Trial

scientific article published on 20 July 2015

Engineered fusokine GIFT4 licenses the ability of B cells to trigger a tumoricidal T-cell response

scientific article published on 17 June 2014

Enzyme replacement therapy in pediatric patients with Gaucher disease: what should we use as maintenance dosage?

scientific article published on 10 December 2008

Epsilon aminocaproic acid prevents bleeding in severely thrombocytopenic patients with hematological malignancies

scientific article

Erythropoietin delivery by genetically engineered bone marrow stromal cells for correction of anemia in mice with chronic renal failure.

scientific article published on 3 May 2006

Evidence for transcriptional regulation of the glucose-6-phosphate transporter by HIF-1alpha: Targeting G6PT with mumbaistatin analogs in hypoxic mesenchymal stromal cells

scientific article published on March 2009

Ex vivo gene therapy for hemophilia A that enhances safe delivery and sustained in vivo factor VIII expression from lentivirally engineered endothelial progenitors

scientific article published on 5 July 2007

Extracellular vesicles from bone marrow-derived mesenchymal stromal cells support ex vivo survival of human antibody secreting cells.

scientific article published on 26 April 2018

FIST, a sword and shield fusokine for cancer immunotherapy

scientific article published on March 2012

Factors of the bone marrow microniche that support human plasma cell survival and immunoglobulin secretion

scientific article published in Nature Communications

From single nucleotide polymorphisms to constant immunosuppression: mesenchymal stem cell therapy for autoimmune diseases

scientific article

GIFT15 fusokine to foil immunity's follies

scientific article published on 01 November 2009

GIFT4 fusokine converts leukemic B cells into immune helper cells

scientific article published on 27 April 2016

GIFT4-augmented B cells for melanoma immunotherapy.

scientific article published on 6 November 2014

GM-CSF and IL-4 Fusion Cytokine Induces B Cell-Dependent Hematopoietic Regeneration

scientific article

GM-CSF-based fusion cytokines as ligands for immune modulation

scientific article published on May 2011

Granulocyte-macrophage colony-stimulating factor and interleukin-2 fusion cDNA for cancer gene immunotherapy.

scientific article

Green fluorescent protein in retroviral vector constructs as marker and reporter of gene expression for cell and gene therapy applications

scientific article

Hierarchical scaffold design for mesenchymal stem cell-based gene therapy of hemophilia B

scientific article

Human MSC suppression correlates with cytokine induction of indoleamine 2,3-dioxygenase and bystander M2 macrophage differentiation

scientific article published on 20 September 2011

Human mesenchymal stromal cells suppress T-cell proliferation independent of heme oxygenase-1

scientific article published on 14 January 2015

Human-compatible collagen matrix for prolonged and reversible systemic delivery of erythropoietin in mice from gene-modified marrow stromal cells

scientific article published on 01 October 2004

Hypoxia promotes murine bone-marrow-derived stromal cell migration and tube formation

scientific article published on January 2003

IDO-independent suppression of T cell effector function by IFN-γ-licensed human mesenchymal stromal cells

scientific article published on 08 January 2014

IFN-γ and indoleamine 2,3-dioxygenase signaling between donor dendritic cells and T cells regulates graft versus host and graft versus leukemia activity

scientific article published on 30 November 2011

Image-Guided Transarterial Directed Delivery of Human Mesenchymal Stem Cells for Targeted Gastrointestinal Therapies in a Swine Model

scientific article published on 06 March 2019

Immune dysfunctionality of replicative senescent mesenchymal stromal cells is corrected by IFNγ priming

scientific article published on 01 April 2017

Immunological characterization of multipotent mesenchymal stromal cells--The International Society for Cellular Therapy (ISCT) working proposal

scientific article published on 17 April 2013

Improved autograft survival of mesenchymal stromal cells by plasminogen activator inhibitor 1 inhibition.

scientific article published in February 2009

Improving mesenchymal stem/stromal cell potency and survival: Proceedings from the International Society of Cell Therapy (ISCT) MSC preconference held in May 2018, Palais des Congrès de Montréal, Organized by the ISCT MSC Scientific Committee

scientific article published on 15 February 2020

In vivo interferon regulatory factor 3 tumor suppressor activity in B16 melanoma tumors

scientific article published in September 2002

Incorporation of a GPI-anchored engineered cytokine as a molecular adjuvant enhances the immunogenicity of HIV VLPs

scientific article published on 7 July 2015

Inducible IL10(+) suppressor B cells inhibit CNS inflammation and T helper 17 polarization

scientific article

Induction of Cardiac Angiogenesis Requires Killer Cell Lectin-Like Receptor 1 and α4β7 Integrin Expression by NK Cells ⬇️

scientific article published on October 22, 2010

Inflammatory monocytes promote progression of Duchenne muscular dystrophy and can be therapeutically targeted via CCR2.

scientific article

Inhibition of cellular senescence by developmentally regulated FGF receptors in mesenchymal stem cells.

scientific article published on 28 April 2011

Inhibition of histone deacetylation in 293GPG packaging cell line improves the production of self-inactivating MLV-derived retroviral vectors

scientific article

Innate immune responses of equine monocytes cultured in equine platelet lysate

scientific article published on 16 November 2017

Interferon-gamma-stimulated marrow stromal cells: a new type of nonhematopoietic antigen-presenting cell

scientific article published on 17 November 2005

International Society for Cellular Therapy perspective on immune functional assays for mesenchymal stromal cells as potency release criterion for advanced phase clinical trials

scientific article

Intravenous mesenchymal stromal cell therapy for inflammatory bowel disease: Lessons from the acute graft versus host disease experience

scientific article

Limited acquisition of chromosomal aberrations in human adult mesenchymal stromal cells

scientific article published on 01 January 2012

Loss of tumorigenicity and metastatic potential in carcinoma cells expressing the extracellular domain of the type 1 insulin-like growth factor receptor

scientific article published in May 2004

Luc Sensébé, champion of MSCs, dies

scientific article published on 08 June 2020

MSCs: science and trials

scientific article published in July 2013

MT1-MMP down-regulates the glucose 6-phosphate transporter expression in marrow stromal cells: a molecular link between pro-MMP-2 activation, chemotaxis, and cell survival.

scientific article published on 17 January 2007

Maltose-binding protein fusion allows for high level bacterial expression and purification of bioactive mammalian cytokine derivatives

scientific article

Manufacturing mesenchymal stromal cells for clinical applications: A survey of Good Manufacturing Practices at U.S. academic centers

scientific article published on 07 June 2019

Marrow stromal cells for interleukin-2 delivery in cancer immunotherapy

scientific article published in June 2004

Matrix metalloproteinase regulation of sphingosine-1-phosphate-induced angiogenic properties of bone marrow stromal cells

scientific article published on July 2003

Matrix metalloproteinases 2 and 9 as diagnostic markers in the progression to Chagas cardiomyopathy

scientific article published on 15 February 2013

Mesenchymal Stromal Cells Derived From Crohn's Patients Deploy Indoleamine 2,3-dioxygenase-mediated Immune Suppression, Independent of Autophagy

scientific article published on 22 April 2015

Mesenchymal Stromal Cells: Clinical Challenges and Therapeutic Opportunities

scientific article published on 01 June 2018

Mesenchymal stromal cell therapeutic potency is dependent upon viability, route of delivery, and immune match

scientific article published on 01 May 2020

Mesenchymal stromal cell-derived CCL2 suppresses plasma cell immunoglobulin production via STAT3 inactivation and PAX5 induction

scientific article

Mesenchymal stromal cells ameliorate experimental autoimmune encephalomyelitis by inhibiting CD4 Th17 T cells in a CC chemokine ligand 2-dependent manner

scientific article

Mesenchymal stromal cells cross-present soluble exogenous antigens as part of their antigen-presenting cell properties

scientific article published on 04 August 2009

Mesenchymal stromal cells engineered to express erythropoietin induce anti-erythropoietin antibodies and anemia in allorecipients

scientific article

Mesenchymal stromal cells expressing ErbB-2/neu elicit protective antibreast tumor immunity in vivo, which is paradoxically suppressed by IFN-gamma and tumor necrosis factor-alpha priming

scientific article published on 5 October 2010

Mesenchymal stromal cells genetically engineered to overexpress IGF-I enhance cell-based gene therapy of renal failure-induced anemia.

scientific article

Mesenchymal stromal cells to modulate immune reconstitution early post-hematopoietic cell transplantation

scientific article

Minor salivary gland mesenchymal stromal cells derived from patients with Sjӧgren's syndrome deploy intact immune plasticity

scientific article published on 28 November 2020

Molecular Genetic and Immune Functional Responses Distinguish Bone Marrow Mesenchymal Stromal Cells from Hepatic Stellate Cells

scientific article published on 09 May 2019

Neo-organoid of marrow mesenchymal stromal cells secreting interleukin-12 for breast cancer therapy.

scientific article published in June 2008

New insights on translational development of mesenchymal stromal cells for suppressor therapy

scientific article

Novel TGF-beta antagonist inhibits tumor growth and angiogenesis by inducing IL-2 receptor-driven STAT1 activation

scientific article published on 06 May 2011

Patient access to and ethical considerations of the application of the European Union hospital exemption rule for advanced therapy medicinal products

scientific article published in 2022

Periostin, a member of a novel family of vitamin K-dependent proteins, is expressed by mesenchymal stromal cells

scientific journal article

Plasminogen Kringle 5 blocks tumor progression by antiangiogenic and proinflammatory pathways

scientific article published on 01 February 2007

Plasminogen kringle 5-engineered glioma cells block migration of tumor-associated macrophages and suppress tumor vascularization and progression

scientific article

Platelet lysate as a novel serum-free media supplement for the culture of equine bone marrow-derived mesenchymal stem cells.

scientific article published on 22 March 2018

Potency Analysis of Mesenchymal Stromal Cells Using a Combinatorial Assay Matrix Approach.

scientific article

Potency Analysis of Mesenchymal Stromal Cells Using a Phospho-STAT Matrix Loop Analytical Approach

scientific article published on 03 June 2019

Properties of immature myeloid progenitors with nitric-oxide-dependent immunosuppressive activity isolated from bone marrow of tumor-free mice

scientific article

Protective role of Indoleamine 2,3 dioxygenase in Respiratory Syncytial Virus associated immune response in airway epithelial cells

scientific article published on 27 September 2017

Rationale and design of Enhanced Angiogenic Cell Therapy in Acute Myocardial Infarction (ENACT-AMI): The first randomized placebo-controlled trial of enhanced progenitor cell therapy for acute myocardial infarction

scientific article published on 01 March 2010

Reciprocal Th1 and Th17 regulation by mesenchymal stem cells: Implication for multiple sclerosis

scientific article published on 01 October 2010

Recurrent obscure gastrointestinal bleeding: dilemmas and success with pharmacological therapies. Case series and review.

scientific article published on September 2009

Regulation of MHC class II expression and antigen processing in murine and human mesenchymal stromal cells by IFN-gamma, TGF-beta, and cell density

scientific article

Regulatory B Cells Induce Formation of IL-10-Expressing T Cells in Mice with Autoimmune Neuroinflammation.

scientific article

Regulatory B cells normalize CNS myeloid cell content in a mouse model of multiple sclerosis and promote oligodendrogenesis and remyelination

scientific article published on 19 May 2020

Reply: "Function of Cryopreserved Mesenchymal Stromal Cells With and Without Interferon-γ Prelicensing Is Context Dependent".

scientific article

Reprogramming of B cells into regulatory cells with engineered fusokines

scientific article published on June 2012

Response to Nature commentary "Clear up this stem-cell mess"

scientific article published on 12 December 2018

Retroviral delivery of connexin genes to human breast tumor cells inhibits in vivo tumor growth by a mechanism that is independent of significant gap junctional intercellular communication

scientific article

Reversible secretome and signaling defects in diabetic mesenchymal stem cells from peripheral arterial disease patients

scientific article published on 10 August 2018

Roles of FGF signaling in stem cell self-renewal, senescence and aging

scientific article

Selective inhibition of CCR2 expressing lymphomyeloid cells in experimental autoimmune encephalomyelitis by a GM-CSF-MCP1 fusokine.

scientific article published in March 2009

Size-exclusion chromatography purification of high-titer vesicular stomatitis virus G glycoprotein-pseudotyped retrovectors for cell and gene therapy applications

scientific article published in August 2003

Stem cell research ethics: consensus statement on emerging issues

scientific article published on October 2007

Stimulation of Natural Killer Cell-Mediated Tumor Immunity by an IL15/TGFβ-Neutralizing Fusion Protein

scientific article published on 3 August 2016

TGF beta secreted by B16 melanoma antagonizes cancer gene immunotherapy bystander effect

scientific article published on 24 January 2008

Tetra- and hexavalent mannosides inhibit the pro-apoptotic, antiproliferative and cell surface clustering effects of concanavalin-A: impact on MT1-MMP functions in marrow-derived mesenchymal stromal cells

scientific article published on 08 December 2007

The Bottom LineMesenchymal Stromal Cells for Graft-versus-Host Disease: A Trilogy

scientific article published on 07 March 2020

The IDO inhibitor 1-methyl tryptophan activates the aryl hydrocarbon receptor response in mesenchymal stromal cells.

scientific article

The N-terminal of the estrogen receptor (ERalpha) mediates transcriptional cross-talk with the retinoic acid receptor in human breast cancer cells

scientific article published on July 2003

The challenge of defining mesenchymal stromal cell potency assays and their potential use as release criteria

scientific article published on February 2015

The effect of platelet lysate fibrinogen on the functionality of MSCs in immunotherapy

scientific article published on 24 July 2013

The human ortholog of granulocyte macrophage colony-stimulating factor and interleukin-2 fusion protein induces potent ex vivo natural killer cell activation and maturation

scientific article

The immune plasticity of mesenchymal stromal cells from mice and men: concordances and discrepancies

article by Raphaelle Romieu-Mourez et al published 1 January 2012 in Frontiers in Bioscience

The mesenchymal stromal cells dilemma--does a negative phase III trial of random donor mesenchymal stromal cells in steroid-resistant graft-versus-host disease represent a death knell or a bump in the road?

scientific article published on January 2013

The nonapoptotic pathway mediating thymidine kinase/ganciclovir toxicity is reduced by signal from adenovirus type 5 early region 4.

scientific article published in February 2002

The stem cell research environment: a patchwork of patchworks

scientific article published on 27 May 2009

Therapeutic angiogenesis using autologous bone marrow stromal cells: improved blood flow in a chronic limb ischemia model

scientific article published on 01 January 2003

Three-dimensional porous scaffolds at the crossroads of tissue engineering and cell-based gene therapy.

scientific article published on October 2009

Tissue engineering of rat bladder using marrow-derived mesenchymal stem cells and bladder acellular matrix

scientific article

Vascular progenitors derived from murine bone marrow stromal cells are regulated by fibroblast growth factor and are avidly recruited by vascularizing tumors

scientific article published on April 2004

Washed equine platelet extract (WEPLEX) as an anti-inflammatory biologic pharmaceutical

scientific article published on 28 August 2020

[A chimeric cytokine to help autoimmune diseases]

scientific article published on 01 February 2010

[The use of mesenchymal stromal cells in oncology and cell therapy]

scientific article published on 01 September 2006

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