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List of works by Jeroen D Langereis

A 2D-DIGE approach to identify proteins involved in inside-out control of integrins.

scientific article

A unique protein profile of peripheral neutrophils from COPD patients does not reflect cytokine-induced protein profiles of neutrophils in vitro

scientific article

A versatile assay to determine bacterial and host factors contributing to opsonophagocytotic killing in hirudin-anticoagulated whole blood

scientific article published on 08 February 2017

Abrogation of NF-κB signaling in human neutrophils induces neutrophil survival through sustained p38-MAPK activation.

scientific article published on 23 June 2010

Alternative Pathway Inhibition by Exogenous Factor H Fails to Attenuate Inflammation and Vascular Leakage in Experimental Pneumococcal Sepsis in Mice

scientific article published on 12 February 2016

Alternative pathway regulation by factor H modulates Streptococcus pneumoniae induced proinflammatory cytokine responses by decreasing C5a receptor crosstalk

scientific article published on 6 October 2016

Antibodies mediate formation of neutrophil extracellular traps in the middle ear and facilitate secondary pneumococcal otitis media

scientific article

Antibody binding and complement-mediated killing of invasive Haemophilus influenzae isolates from Spain, Portugal, and the Netherlands

scientific article published on 27 July 2020

Bacterial Lysis through Interference with Peptidoglycan Synthesis Increases Biofilm Formation by Nontypeable Haemophilus influenzae

scientific article

Binding of human factor H to outer membrane protein P5 of non-typeable Haemophilus influenzae contributes to complement resistance

scientific article published on 18 August 2014

Complement Factor H Serum Levels Determine Resistance to Pneumococcal Invasive Disease

scientific article published on 21 January 2016

Complement factor D haplodeficiency is associated with a reduced complement activation speed and diminished bacterial killing

scientific article published in 2021

Desialylation of Platelets by Pneumococcal Neuraminidase A Induces ADP-Dependent Platelet Hyperreactivity

scholarly article published by Jeroen D Langereis in 2018

From microbial gene essentiality to novel antimicrobial drug targets

scientific article

Functional antagonism by GM-CSF on TNF-α-induced CD83 expression in human neutrophils

scientific article published on 27 August 2008

GM-CSF and TNFα modulate protein expression of human neutrophils visualized by fluorescence two-dimensional difference gel electrophoresis

scientific article published on 27 August 2011

Genetic background impacts vaccine-induced reduction of pneumococcal colonization

scientific article published on 16 August 2017

Genetic requirements for Moraxella catarrhalis growth under iron‐limiting conditions ⬇️

scientific article published on November 19, 2012

IFN-γ-stimulated neutrophils suppress lymphocyte proliferation through expression of PD-L1.

scientific article

IgM Augments Complement Bactericidal Activity with Serum from a Patient with a Novel CD79a Mutation.

scientific article

Incorporation of phosphorylcholine into the lipooligosaccharide of nontypeable Haemophilus influenzae does not correlate with the level of biofilm formation in vitro

scientific article published on 22 January 2014

Increased biofilm formation by nontypeable Haemophilus influenzae isolates from patients with invasive disease or otitis media versus strains recovered from cases of respiratory infections

scientific article published on 5 September 2014

Intranasal vaccination with protein bodies elicit strong protection against Streptococcus pneumoniae colonization

scientific article published in 2021

Invasive Disease Caused by Nontypeable Haemophilus influenzae

scientific article

Metabolic Oligosaccharide Engineering with Alkyne Sialic Acids Confers Neuraminidase Resistance and Inhibits Influenza Reproduction.

scientific article published on 21 June 2017

Modified lipooligosaccharide structure protects nontypeable Haemophilus influenzae from IgM-mediated complement killing in experimental otitis media.

scientific article

Multi-component meningococcal serogroup B (MenB)-4C vaccine induces effective opsonophagocytic killing in children with a complement deficiency

scientific article published on 01 October 2019

Nasal Delivery of a Commensal Pasteurellaceae Species Inhibits Nontypeable Haemophilus influenzae Colonization and Delays Onset of Otitis Media in Mice

scientific article published on 23 March 2020

Neutrophil integrin affinity regulation in adhesion, migration, and bacterial clearance.

scientific article

Non-encapsulated Streptococcus pneumoniae, vaccination as a measure to interfere with horizontal gene transfer.

scientific article published on 22 March 2017

Nontypeable Haemophilus influenzae Invasive Blood Isolates Are Mainly Phosphorylcholine Negative and Show Decreased Complement-Mediated Killing That Is Associated with Lower Binding of IgM and CRP in Comparison to Colonizing Isolates from the Orophar ⬇️

scientific article published on 24 January 2019

Nontypeable Haemophilus influenzae carbonic anhydrase is important for environmental and intracellular survival.

scientific article published on 5 April 2013

Novel concepts in nontypeable Haemophilus influenzae biofilm formation.

scientific article published on 15 July 2013

Physiological concentrations of leptin do not affect human neutrophils

scientific article

Plasma therapy leads to an increase in functional IgA and IgM concentration in the blood and saliva of a patient with X-linked agammaglobulinemia

scientific article published on 23 May 2019

Proteomic profiling of peripheral blood neutrophils identifies two inflammatory phenotypes in stable COPD patients

scientific article

Quantitative multiplex profiling of the complement system to diagnose complement-mediated diseases

scientific article published on 09 December 2020

Resistance to complement-mediated killing and IgM binding to non-typeable Haemophilus influenzae is not altered when ascending from the nasopharynx to the middle ears in children with otitis media

scientific article published on 18 June 2013

Serum IgM and C-Reactive Protein Binding to Phosphorylcholine of Nontypeable Haemophilus influenzae Increases Complement-Mediated Killing

scientific article published on 23 July 2019

Shielding of a lipooligosaccharide IgM epitope allows evasion of neutrophil-mediated killing of an invasive strain of nontypeable Haemophilus influenzae ⬇️

scientific article

Spleen-derived IFN-γ induces generation of PD-L1(+)-suppressive neutrophils during endotoxemia

scientific article published on 3 October 2017

Steroids induce a disequilibrium of secreted interleukin-1 receptor antagonist and interleukin-1 synthesis by human neutrophils

scientific article published on 22 July 2010

Streptococcus pneumoniae PspC-subgroup prevalence in invasive disease and difference in contribution to complement evasion.

scientific article

Th17-mediated cross protection against pneumococcal carriage by vaccination with a variable antigen

scientific article published on 20 September 2017

The complement system contributes to functional antibody-mediated responses induced by immunization with Plasmodium falciparum malaria sporozoites.

scientific article published on 7 May 2018

The contribution of the alternative pathway in complement activation on cell surfaces depends on the strength of classical pathway initiation

scientific article published in 2023

Uptake of Sialic Acid by Nontypeable Haemophilus influenzae Increases Complement Resistance through Decreasing IgM-Dependent Complement Activation

scientific article published on 21 May 2019

Variable processing of the IgA protease autotransporter at the cell surface of Neisseria meningitidis.

scientific article published on 26 August 2014

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