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List of works by Cornelia Barbara Landersdorfer

Acrylamide: increased concentrations in homemade food and first evidence of its variable absorption from food, variable metabolism and placental and breast milk transfer in humans.

scientific article published in January 2002

Aminoglycoside Concentrations Required for Synergy with Carbapenems against Pseudomonas aeruginosa Determined via Mechanistic Studies and Modeling

scientific article published on 11 September 2017

An optimised Cu(0)-RDRP approach for the synthesis of lipidated oligomeric vinyl azlactone: toward a versatile antimicrobial materials screening platform

scientific article published on 11 October 2019

Bone penetration of amoxicillin and clavulanic acid evaluated by population pharmacokinetics and Monte Carlo simulation

scientific article published on 23 March 2009

Characterizing the time-course of antihypertensive activity and optimal dose range of fimasartan via mechanism-based population modeling

scientific article published on 06 June 2017

Clinically relevant concentrations of fosfomycin combined with polymyxin B, tobramycin or ciprofloxacin enhance bacterial killing of Pseudomonas aeruginosa, but do not suppress the emergence of fosfomycin resistance.

scientific article published on 26 April 2016

Colistin and doripenem combinations against Pseudomonas aeruginosa: profiling the time course of synergistic killing and prevention of resistance

scientific article

Colistin: how should it be dosed for the critically ill?

scientific article

Combating carbapenem-resistant Acinetobacter baumannii by an optimized imipenem plus tobramycin dosage regimen - prospective validation via hollow fiber infection and mathematical modeling

scientific article published on 16 January 2018

Combination therapy for carbapenem-resistant Gram-negative bacteria

scientific article

Comparable Bioavailability and Disposition of Pefloxacin in Patients with Cystic Fibrosis and Healthy Volunteers Assessed via Population Pharmacokinetics

scientific article published on 10 July 2019

Comparative pharmacodynamics of four different carbapenems in combination with polymyxin B against carbapenem-resistant Acinetobacter baumannii

scientific article published on 20 September 2016

Comparison of the pharmacokinetics and pharmacodynamic profile of carumonam in cystic fibrosis patients and healthy volunteers

scientific article published in October 2009

Competitive inhibition of renal tubular secretion of ciprofloxacin and metabolite by probenecid

scientific article

Competitive inhibition of renal tubular secretion of gemifloxacin by probenecid

scientific article published on 29 June 2009

Conjugation of 10 kDa Linear PEG onto Trastuzumab Fab' Is Sufficient to Significantly Enhance Lymphatic Exposure while Preserving in Vitro Biological Activity

scientific article published on 12 February 2016

Development of a new pre- and post-processing tool (SADAPT-TRAN) for nonlinear mixed-effects modeling in S-ADAPT.

scientific article published on 3 March 2011

Differences in suppression of regrowth and resistance despite similar initial bacterial killing for meropenem and piperacillin/tazobactam against Pseudomonas aeruginosa and Escherichia coli.

scientific article published on 3 January 2018

Effect of different renal function on antibacterial effects of piperacillin against Pseudomonas aeruginosa evaluated via the hollow-fibre infection model and mechanism-based modelling.

scientific article published on 26 May 2016

Elucidation of the pharmacokinetic/pharmacodynamic determinants of fosfomycin activity against Pseudomonas aeruginosa using a dynamic in vitro model

scientific article

Evaluation by monte carlo simulation of the pharmacokinetics of two doses of meropenem administered intermittently or as a continuous infusion in healthy volunteers.

scientific article

Evaluation of Pharmacokinetic/Pharmacodynamic Model-Based Optimized Combination Regimens against Multidrug-Resistant Pseudomonas aeruginosa in a Murine Thigh Infection Model by Using Humanized Dosing Schemes

scientific article

Evaluation of Tobramycin and Ciprofloxacin as a Synergistic Combination Against Hypermutable Pseudomonas Aeruginosa Strains via Mechanism-Based Modelling

scientific article published on 12 September 2019

Evaluation of enrofloxacin use in koalas (Phascolarctos cinereus) via population pharmacokinetics and Monte Carlo simulation.

scientific article

External manipulation of nanostructure in photoresponsive lipid depot matrix to control and predict drug release in vivo.

scientific article

Extracorporeal clearance of colistin methanesulphonate and formed colistin in end-stage renal disease patients receiving intermittent haemodialysis: implications for dosing

scientific article published on 18 February 2015

Four Decades of β-Lactam Antibiotic Pharmacokinetics in Cystic Fibrosis

scientific article published on 01 February 2019

High-intensity meropenem combinations with polymyxin B: new strategies to overcome carbapenem resistance in Acinetobacter baumannii

scientific article published on 15 September 2016

In reply

scientific article published on 16 November 2017

Inhibition of flucloxacillin tubular renal secretion by piperacillin

scientific article

Lessons learned in the development of sustained release penicillin drug delivery systems for the prophylactic treatment of rheumatic heart disease (RHD).

scientific article

Lithium in Paediatric Patients with Bipolar Disorder: Implications for Selection of Dosage Regimens via Population Pharmacokinetics/Pharmacodynamics.

scientific article published in January 2017

Mechanism‐based population modelling of the effects of vildagliptin on GLP‐1, glucose and insulin in patients with type 2 diabetes ⬇️

scientific article published on March 1, 2012

Mechanism‐based population pharmacokinetic modelling in diabetes: vildagliptin as a tight binding inhibitor and substrate of dipeptidyl peptidase IV ⬇️

scientific article published on March 1, 2012

Meropenem-Tobramycin Combination Regimens Combat Carbapenem-Resistant Pseudomonas aeruginosa in the Hollow-Fiber Infection Model Simulating Augmented Renal Clearance in Critically Ill Patients

scientific article published on 20 December 2019

Novel approach to optimize synergistic carbapenem-aminoglycoside combinations against carbapenem-resistant Acinetobacter baumannii

scientific article

Optimization and evaluation of piperacillin plus tobramycin combination dosage regimens against Pseudomonas aeruginosa for patients with altered pharmacokinetics via the hollow-fiber infection model and mechanism-based modeling

scientific article published on 20 February 2018

Optimization of Synergistic Combination Regimens against Carbapenem- and Aminoglycoside-Resistant Clinical Pseudomonas aeruginosa Isolates via Mechanism-Based Pharmacokinetic/Pharmacodynamic Modeling

scientific article

Optimization of a meropenem plus tobramycin combination dosage regimen against hypermutable and non-hypermutable Pseudomonas aeruginosa via mechanism-based modeling and the hollow-fiber infection model.

scientific article published on 5 February 2018

Optimization of dosing regimens of intravenous colistin in patients with cystic fibrosis: What data are required?

scientific article published on 08 July 2019

Optimizing Polymyxin Combinations Against Resistant Gram-Negative Bacteria

scientific article

PK/PD models in antibacterial development.

scientific article published on 18 July 2013

Paradoxical Effect of Polymyxin B: High Drug Exposure Amplifies Resistance in Acinetobacter baumannii

scientific article published on 11 April 2016

Penetration of antibacterials into bone: pharmacokinetic, pharmacodynamic and bioanalytical considerations

scientific article published on January 2009

Penetration of moxifloxacin into bone evaluated by Monte Carlo simulation

scientific article published on 17 February 2009

Performance and robustness of the Monte Carlo importance sampling algorithm using parallelized S-ADAPT for basic and complex mechanistic models.

scientific article published on 4 March 2011

Performance of four fosfomycin susceptibility testing methods against an international collection of clinical Pseudomonas aeruginosa isolates

scientific article published on 15 July 2020

Personalizing Polymyxin B Dosing Using an Adaptive Feedback Control Algorithm.

scientific article published on 14 May 2018

Pharmacodynamic modeling of anti-cancer activity of tetraiodothyroacetic acid in a perfused cell culture system

scientific article

Pharmacokinetic modeling and simulation of biweekly subcutaneous immunoglobulin dosing in primary immunodeficiency.

scientific article

Pharmacokinetic modelling of modified acetylcysteine infusion regimens used in the treatment of paracetamol poisoning

scientific article published on 17 June 2017

Pharmacokinetic/pharmacodynamic modeling of glucose clamp effects of inhaled and subcutaneous insulin in healthy volunteers and diabetic patients.

scientific article published on 30 September 2010

Pharmacokinetic/pharmacodynamic modelling in diabetes mellitus.

scientific article published on January 2008

Pharmacokinetics and pharmacodynamics of 'old' polymyxins: what is new?

scientific article

Pharmacokinetics and pharmacodynamics of antibiotics in intensive care

scientific article published on 24 October 2016

Pharmacokinetics of colistin methanesulfonate and formed colistin in end-stage renal disease patients receiving continuous ambulatory peritoneal dialysis

scientific article

Pharmacokinetics of polymyxin B in patients on continuous venovenous haemodialysis ⬇️

scientific article published on November 23, 2012

Pharmacokinetics/pharmacodynamics of systemically administered polymyxin B against Klebsiella pneumoniae in mouse thigh and lung infection models

scientific article published on 14 November 2017

Pharmakokinetik und Pharmakodynamik der β-Lactame: Was wir über β-Lactame wissen und was wir wissen möchten

scientific article published on 01 January 2006

Polymyxin B in combination with doripenem against heteroresistant Acinetobacter baumannii: pharmacodynamics of new dosing strategies

scientific article published on 3 August 2016

Polymyxin combinations: pharmacokinetics and pharmacodynamics for rationale use.

scientific article published on January 2015

Population Pharmacokinetic Analyses for Ertapenem in Subjects with a Wide Range of Body Sizes

scientific article published on 24 September 2018

Population Pharmacokinetic Modeling of the Enterohepatic Recirculation of Fimasartan in Rats, Dogs, and Humans

scientific article

Population Pharmacokinetic/Pharmacodynamic Modelling of Dipeptidyl Peptidase IV Inhibitors

scientific article published on 01 July 2015

Population Pharmacokinetics and Penetration into Prostatic, Seminal, and Vaginal Fluid for Ciprofloxacin, Levofloxacin, and Their Combination

scientific article published on 18 October 2011

Population pharmacokinetics at two dose levels and pharmacodynamic profiling of flucloxacillin

scientific article

Population pharmacokinetics of intravenous polymyxin B in critically ill patients: implications for selection of dosage regimens.

scientific article published on 22 May 2013

Population pharmacokinetics of piperacillin at two dose levels: influence of nonlinear pharmacokinetics on the pharmacodynamic profile

scientific article

Quantifying subpopulation synergy for antibiotic combinations via mechanism-based modeling and a sequential dosing design

scientific article published on 11 March 2013

Quantitative Determination of Absorption and First-Pass Metabolism of Apicidin, a Potent Histone Deacetylase Inhibitor

scientific article published on 18 March 2014

Relevance of Pharmacokinetic and Pharmacodynamic Modeling to Clinical Care of Critically Ill Patients ⬇️

scientific article published on December 1, 2011

Reply to Pai

scientific article published on 18 September 2013

Resistance suppression by high-intensity, short-duration aminoglycoside exposure against hypermutable and non-hypermutable Pseudomonas aeruginosa

scientific article published on 11 August 2016

Shape does matter: short high-concentration exposure minimizes resistance emergence for fluoroquinolones in Pseudomonas aeruginosa

scientific article published on 06 November 2014

Study Reanalysis Using a Mechanism-Based Pharmacokinetic/Pharmacodynamic Model of Pramlintide in Subjects with Type 1 Diabetes ⬇️

scientific article published on October 2, 2012

Substantial Impact of Altered Pharmacokinetics in Critically Ill Patients on the Antibacterial Effects of Meropenem Evaluated via the Dynamic Hollow-Fiber Infection Model

scientific article published on 6 March 2017

Substantial Targeting Advantage Achieved by Pulmonary Administration of Colistin Methanesulfonate in a Large-Animal Model.

scientific article

Synergistic Meropenem-Tobramycin Combination Dosage Regimens against Clinical Hypermutable Pseudomonas aeruginosa at Simulated Epithelial Lining Fluid Concentrations in a Dynamic Biofilm Model

scientific article published on 22 October 2019

The time course of drug effects.

scientific article published on July 2009

Two mechanisms of killing of Pseudomonas aeruginosa by tobramycin assessed at multiple inocula via mechanism-based modeling.

scientific article

Two new antibiotics with special qualities: the pharmacokinetics of linezolid and telithromycin

scientific article published in January 2004

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