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List of works by Roberta Foresti

A carbon monoxide-releasing molecule (CORM-3) exerts bactericidal activity against Pseudomonas aeruginosa and improves survival in an animal model of bacteraemia

scientific article

Anti-inflammatory activities of carbon monoxide-releasing molecules (CO-RMs) in the brain

scientific article published on 12 June 2015

Beneficial effects of carbon monoxide-releasing molecules on post-ischemic myocardial recovery

scientific article published on 02 February 2007

Bilirubin decreases nos2 expression via inhibition of NAD(P)H oxidase: implications for protection against endotoxic shock in rats

scientific article

Bioactive properties of iron-containing carbon monoxide-releasing molecules

scientific article published on 7 April 2006

Bioactivity and pharmacological actions of carbon monoxide-releasing molecules

scientific article published on January 2003

Biological signaling by carbon monoxide and carbon monoxide-releasing molecules

scientific article published on 11 January 2017

CO-releasing molecules: avoiding toxicity and exploiting the beneficial effects of CO for the treatment of cardiovascular disorders

scientific article

CORM-3, a carbon monoxide-releasing molecule, alters the inflammatory response and reduces brain damage in a rat model of hemorrhagic stroke

scientific article published in February 2012

CORM-A1: a new pharmacologically active carbon monoxide-releasing molecule

scientific article published on 19 November 2004

Caffeic acid phenethyl ester and curcumin: a novel class of heme oxygenase-1 inducers

scientific article published in March 2002

Carbon monoxide inhibits TLR-induced dendritic cell immunogenicity

scientific article published in February 2009

Carbon monoxide is a major contributor to the regulation of vascular tone in aortas expressing high levels of haeme oxygenase-1

scientific article

Carbon monoxide released by CORM-401 uncouples mitochondrial respiration and inhibits glycolysis in endothelial cells: A role for mitoBKCa channels

scientific article published on 13 July 2015

Carbon monoxide reverses the metabolic adaptation of microglia cells to an inflammatory stimulus

scientific article published on 18 January 2017

Carbon monoxide-induced metabolic switch in adipocytes improves insulin resistance in obese mice

scholarly article by Laura Braud et al published 15 November 2018 in JCI insight

Carbon monoxide-releasing molecules (CO-RMs) attenuate the inflammatory response elicited by lipopolysaccharide in RAW264.7 murine macrophages

scientific article

Carbon monoxide-releasing molecules (CO-RMs) modulate respiration in isolated mitochondria

scientific article

Carbon monoxide-releasing molecules: characterization of biochemical and vascular activities.

scientific article published in February 2002

Cardioprotective actions by a water-soluble carbon monoxide-releasing molecule

scientific article published on 3 July 2003

Changes in temperature modulate heme oxygenase-1 induction by curcumin in renal epithelial cells

scientific article published in September 2003

Curcumin activates the haem oxygenase-1 gene via regulation of Nrf2 and the antioxidant-responsive element

scientific article

Curcumin reduces cold storage-induced damage in human cardiac myoblasts

scientific article

Curcumin, an antioxidant and anti-inflammatory agent, induces heme oxygenase-1 and protects endothelial cells against oxidative stress

scientific article published on 01 April 2000

Design and Biological Evaluation of Manganese- and Ruthenium-Based Hybrid CO-RMs (HYCOs)

scientific article published on 23 August 2019

Design and Synthesis of New Hybrid Molecules That Activate the Transcription Factor Nrf2 and Simultaneously Release Carbon Monoxide

scientific article published on 15 September 2014

Detection and Removal of Endogenous Carbon Monoxide by Selective and Cell-Permeable Hemoprotein Model Complexes

scientific article

Differential Antibacterial Activity Against Pseudomonas aeruginosa by Carbon Monoxide-Releasing Molecules

scientific article published on 15 September 2011

Differential activation of heme oxygenase-1 by chalcones and rosolic acid in endothelial cells

scientific article published on 10 November 2004

Diverse Nrf2 Activators Coordinated to Cobalt Carbonyls Induce Heme Oxygenase-1 and Release Carbon Monoxide in Vitro and in Vivo

scientific article published on 5 January 2016

Dynamics of haem oxygenase-1 expression and bilirubin production in cellular protection against oxidative stress.

scientific article published in June 2000

Effects of 3-Bromo-4,5-dihydroisoxazole Derivatives on Nrf2 Activation and Heme Oxygenase-1 Expression

scientific article published on 12 October 2018

Effects of Novel Nitric Oxide-Releasing Molecules against Oxidative Stress on Retinal Pigmented Epithelial Cells

scientific article published on 12 October 2017

Emerging concepts on the anti-inflammatory actions of carbon monoxide-releasing molecules (CO-RMs) ⬇️

scientific article published on November 21, 2012

Endothelial Heme Oxygenase-1 Induction by Hypoxia

scientific article published in Journal of Biological Chemistry

Generation of bile pigments by haem oxygenase: a refined cellular strategy in response to stressful insults.

scientific article

HYCO-3, a dual CO-releaser/Nrf2 activator, reduces tissue inflammation in mice challenged with lipopolysaccharide

scientific article published on 26 October 2018

Haem and nitric oxide: synergism in the modulation of the endothelial haem oxygenase-1 pathway

scientific article published on June 2003

Heme Oxygenase-1 and Carbon Monoxide in the Heart: The Balancing Act Between Danger Signaling and Pro-Survival

scientific article

Heme Oxygenase-1–Derived Carbon Monoxide Contributes to the Suppression of Acute Hypertensive Responses In Vivo

article

Heme oxygenase activity modulates vascular endothelial growth factor synthesis in vascular smooth muscle cells

scientific article

Heme oxygenase-1 as a target for drug discovery

scientific article published on 28 February 2014

Heme oxygenase-1 in diabetic vascular dysfunction

scientific article published on 23 May 2014

Heme oxygenase-1 induction attenuates senescence in chronic obstructive pulmonary disease lung fibroblasts by protecting against mitochondria dysfunction

scientific article published on 19 October 2018

Heme oxygenase-1 induction in skeletal muscle cells: hemin and sodium nitroprusside are regulators in vitro

scientific article published on October 1998

Heme oxygenase-1 mediates the anti-inflammatory actions of 2'-hydroxychalcone in RAW 264.7 murine macrophages

scientific article published on 16 November 2005

Heme oxygenase-1-derived bilirubin ameliorates postischemic myocardial dysfunction

scientific article published on 01 February 2000

Homocysteine attenuates endothelial haem oxygenase-1 induction by nitric oxide (NO) and hypoxia

scientific article published in November 2001

Human and murine macrophages exhibit differential metabolic responses to lipopolysaccharide - A divergent role for glycolysis

article

Human sickle cell blood modulates endothelial heme oxygenase activity: effects on vascular adhesion and reactivity

scientific article published on 3 December 2009

Induction of heme oxygenase 1 by nitrosative stress. A role for nitroxyl anion

scientific article published on 22 August 2002

Interaction of bilirubin and biliverdin with reactive nitrogen species

scientific article published in May 2003

Interaction of carbon monoxide with transition metals: evolutionary insights into drug target discovery

scientific article published on December 2010

Interaction of heme with nitroxyl or nitric oxide amplifies heme oxygenase-1 induction: involvement of the transcription factor Nrf2.

scientific article published on December 2002

Isothiocyanate-cysteine conjugates protect renal tissue against cisplatin-induced apoptosis via induction of heme oxygenase-1.

scientific article published on 13 January 2014

Mesenchymal stem cells sense mitochondria released from damaged cells as danger signals to activate their rescue properties

scientific article

Metal Carbonyls: A New Class of Pharmaceuticals?

scientific article published on 01 August 2003

Metal carbonyls as pharmaceuticals? [Ru(CO)3Cl(glycinate)], a CO-releasing molecule with an extensive aqueous solution chemistry

scientific article

Methylation of estrogen receptor alpha and mutL homolog 1 in normal colonic mucosa: association with folate and vitamin B-12 status in subjects with and without colorectal neoplasia

scientific article published in October 2007

NO-mediated activation of heme oxygenase: endogenous cytoprotection against oxidative stress to endothelium

scientific article

Nitric oxide synthase is present in the cerebrospinal fluid of patients with active multiple sclerosis and is associated with increases in cerebrospinal fluid protein nitrotyrosine and S-nitrosothiols and with changes in glutathione levels

scientific article published in November 2002

Nrf2 activators modulate oxidative stress responses and bioenergetic profiles of human retinal epithelial cells cultured in normal or high glucose conditions

scientific article published on 15 July 2015

Oxidative-stress response in vascular endothelial cells exposed to acellular hemoglobin solutions

scientific article published in August 1995

Permanent culture of macrophages at physiological oxygen attenuates the antioxidant and immunomodulatory properties of dimethyl fumarate

scientific article published in May 2015

Peroxynitrite induces haem oxygenase-1 in vascular endothelial cells: a link to apoptosis.

scientific article published on May 1999

Pharmacology of the 'gasotransmitters' NO, CO and H2S: translational opportunities

scientific article published in March 2015

Protective role of heme oxygenases against endotoxin-induced diaphragmatic dysfunction in rats

scientific article published in March 2001

Regulation of heme oxygenase-1 by redox signals involving nitric oxide

scientific article

Regulation of vascular tone in rabbit ophthalmic artery: cross talk of endogenous and exogenous gas mediators

scientific article published on 29 October 2014

Reviewing the use of carbon monoxide-releasing molecules (CO-RMs) in biology: implications in endotoxin-mediated vascular dysfunction.

scientific article

Role of heme oxygenase-1 in hypoxia-reoxygenation: requirement of substrate heme to promote cardioprotection.

scientific article published in November 2001

Small molecule activators of the Nrf2-HO-1 antioxidant axis modulate heme metabolism and inflammation in BV2 microglia cells

scientific article

Structure-activity relationships of methoxychalcones as inducers of heme oxygenase-1.

scientific article published on 12 June 2008

TLR4 activation alters labile heme levels to regulate BACH1 and heme oxygenase-1 expression in macrophages

scientific article published on 24 April 2019

The autoxidation of alpha alpha cross-linked hemoglobin: a possible role in the oxidative stress to endothelium

scientific article

The heme oxygenase pathway and its interaction with nitric oxide in the control of cellular homeostasis

scientific article

The interaction of nitric oxide with distinct hemoglobins differentially amplifies endothelial heme uptake and heme oxygenase-1 expression

scientific article published on 22 February 2006

Therapeutic applications of carbon monoxide-releasing molecules

scientific article

Thiol Compounds Interact with Nitric Oxide in Regulating Heme Oxygenase-1 Induction in Endothelial Cells

scientific article published in Journal of Biological Chemistry

Treatment with CO-RMs during cold storage improves renal function at reperfusion.

scientific article published in January 2006

Use of carbon monoxide as a therapeutic agent: promises and challenges

scientific article

Vascular and angiogenic activities of CORM-401, an oxidant-sensitive CO-releasing molecule

scientific article published on 22 December 2015

Vasoactive properties of CORM-3, a novel water-soluble carbon monoxide-releasing molecule

scientific article published on 17 May 2004

Vasorelaxing effects and inhibition of nitric oxide in macrophages by new iron-containing carbon monoxide-releasing molecules (CO-RMs).

scientific article published on 17 December 2012

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