List of works by Gérard Gradwohl

A transcriptomic roadmap to α- and β-cell differentiation in the embryonic pancreas

scientific article published on 24 June 2019

Competence of failed endocrine progenitors to give rise to acinar but not ductal cells is restricted to early pancreas development

scientific article published on 26 October 2011

Conditional deletion of neurogenin-3 using Nkx2.1iCre results in a mouse model for the central control of feeding, activity and obesity

scientific article published on 02 May 2013

Crossregulation between Neurogenin2 and pathways specifying neuronal identity in the spinal cord

scientific article published on 01 August 2001

Differential requirements for neurogenin 3 in the development of POMC and NPY neurons in the hypothalamus ⬇️

scientific article published on November 11, 2010

Differentially Expressed MicroRNA-483 Confers Distinct Functions in Pancreatic β- and α-Cells.

scientific article published on 24 June 2015

Dominant-negative and targeted null mutations in the endothelial receptor tyrosine kinase, tek, reveal a critical role in vasculogenesis of the embryo

scientific journal article

Dorsal pancreas agenesis in retinoic acid-deficient Raldh2 mutant mice

scientific journal article

Expression and functional studies of the GDNF family receptor alpha 3 in the pancreas

scientific article published on 17 November 2015

Expression in E. coli of the catalytic domain of rat poly(ADP-ribose)polymerase

scientific article published on 01 May 1990

Expression of neuropeptide Y and agouti-related peptide in the hypothalamic arcuate nucleus of newborn neurogenin3 null mutant mice

scientific article

GeneSpeed Beta Cell: an online genomics data repository and analysis resource tailored for the islet cell biologist.

scientific article

Hes1 and Hes5 as notch effectors in mammalian neuronal differentiation.

scientific article

IA1 is NGN3-dependent and essential for differentiation of the endocrine pancreas

scientific article

Neurogenin3 is differentially required for endocrine cell fate specification in the intestinal and gastric epithelium

scientific article

Neurogenin3 participates in gliogenesis in the developing vertebrate spinal cord.

scientific article published in January 2003

Opposing actions of Arx and Pax4 in endocrine pancreas development ⬇️

scientific article published on October 15, 2003

Pairing-up SOX to kick-start beta cell genesis.

scientific article

Pak3 promotes cell cycle exit and differentiation of β-cells in the embryonic pancreas and is necessary to maintain glucose homeostasis in adult mice

scientific article published on 25 October 2013

Pancreatic islet and progenitor cell surface markers with cell sorting potential

scientific article published on 23 September 2011

Pancreatic islet progenitor cells in neurogenin 3-yellow fluorescent protein knock-add-on mice.

scientific article published on 5 August 2004

Poly(ADP-ribose) polymerase forms loops with DNA

scientific article published on 01 November 1987

Restricted expression of a novel murine atonal-related bHLH protein in undifferentiated neural precursors.

scientific article

Rfx6 is an Ngn3-dependent winged helix transcription factor required for pancreatic islet cell development

scientific article

Rfx6 maintains the functional identity of adult pancreatic β cells.

scientific article

Rfx6 promotes the differentiation of peptide-secreting enteroendocrine cells while repressing genetic programs controlling serotonin production

scientific article published on 13 August 2019

STAT3 modulates β-cell cycling in injured mouse pancreas and protects against DNA damage

scientific article published on 23 June 2016

Short-term overexpression of VEGF-A in mouse beta cells indirectly stimulates their proliferation and protects against diabetes.

scientific article published in January 2014

Temporal control of neurogenin3 activity in pancreas progenitors reveals competence windows for the generation of different endocrine cell types.

scientific article

The bHLH protein NEUROGENIN 2 is a determination factor for epibranchial placode-derived sensory neurons.

scientific article

The homeodomain-containing transcription factors Arx and Pax4 control enteroendocrine subtype specification in mice

scientific article

The transcriptional co-repressor Grg3/Tle3 promotes pancreatic endocrine progenitor delamination and β-cell differentiation.

scientific article published in April 2012

Transcription factor PROX1 induces colon cancer progression by promoting the transition from benign to highly dysplastic phenotype

scientific article

Transcription factor hepatocyte nuclear factor 6 regulates pancreatic endocrine cell differentiation and controls expression of the proendocrine gene ngn3

scientific journal article

Transcriptional program of the endocrine pancreas in mice and humans.

scientific article

Zinc-binding proteins detected by protein blotting

scientific article published on 01 July 1988

neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas

scientific article

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