List of works - Dean Burkin

A functional role for specific spliced variants of the alpha7beta1 integrin in acetylcholine receptor clustering

scientific article

A molecular bandage for diseased muscle

scientific article published on 01 June 2012

Activation of AKT signaling promotes cell growth and survival in α7β1 integrin-mediated alleviation of muscular dystrophy

scientific article published on 7 January 2011

Activation of volume regulated chloride channels protects myocardium from ischemia/reperfusion damage in second-window ischemic preconditioning.

scientific article published on 16 December 2011

Alpha 7 integrin preserves the function of the extensor digitorum longus muscle in dystrophin-null mice

scientific article published on 29 August 2013

Alpha7beta1-integrin regulates mechanotransduction and prevents skeletal muscle injury

scientific article published on 18 January 2006

Bit-1 is an essential regulator of myogenic differentiation

scientific article published on 13 March 2015

Cardiac-specific, inducible ClC-3 gene deletion eliminates native volume-sensitive chloride channels and produces myocardial hypertrophy in adult mice

scientific article

Diagnosis and etiology of congenital muscular dystrophy

scientific article published on 26 December 2007

Dystrophin and utrophin expression require sarcospan: loss of α7 integrin exacerbates a newly discovered muscle phenotype in sarcospan-null mice

scientific article

ECM-Related Myopathies and Muscular Dystrophies: Pros and Cons of Protein Therapies

scientific article published on 12 September 2017

Enhanced expression of the alpha 7 beta 1 integrin reduces muscular dystrophy and restores viability in dystrophic mice

scientific article

Evaluation of the behavioral characteristics of the mdx mouse model of duchenne muscular dystrophy through operant conditioning procedures

scientific article published on 19 May 2017

Exercise promotes alpha7 integrin gene transcription and protection of skeletal muscle

scientific article published on 10 September 2008

Four human chromosome 3q and four human chromosome 21 loci map onto sheep chromosome 1q

scientific article published on 01 March 1995

Four loci from human chromosome 1 are physically assigned to sheep chromosome 1p

scientific article published on 01 August 1995

Galectin-1 Protein Therapy Prevents Pathology and Improves Muscle Function in the mdx Mouse Model of Duchenne Muscular Dystrophy

scientific article

Heart-specific overexpression of the human short CLC-3 chloride channel isoform limits myocardial ischemia-induced ERP and QT prolongation

scientific article published on 30 March 2016

Human laminin-111 and laminin-211 protein therapy prevents muscle disease progression in an immunodeficient mouse model of LAMA2-CMD

scientific article published on 04 June 2020

Impaired fetal muscle development and JAK-STAT activation mark disease onset and progression in a mouse model for merosin-deficient congenital muscular dystrophy

scientific article published on 7 March 2017

Improving Reproducibility of Phenotypic Assessments in the DyW Mouse Model of Laminin-α2 Related Congenital Muscular Dystrophy

scientific article

Increasing alpha 7 beta 1-integrin promotes muscle cell proliferation, adhesion, and resistance to apoptosis without changing gene expression

scientific article published on 28 November 2007

Integrin α7: a major driver and therapeutic target for glioblastoma malignancy

scientific article published on 18 December 2017

Isolation of chromosome-specific paints from high-resolution flow karyotypes of the sheep (Ovis aries).

scientific article published on April 1997

Laminin and alpha7beta1 integrin regulate agrin-induced clustering of acetylcholine receptors

scientific article (publication date: August 2000)

Laminin-111 improves muscle repair in a mouse model of merosin-deficient congenital muscular dystrophy

scientific article published on 5 September 2013

Laminin-111 protein therapy prevents muscle disease in the mdx mouse model for Duchenne muscular dystrophy

scholarly article

Laminin-111 protein therapy reduces muscle pathology and improves viability of a mouse model of merosin-deficient congenital muscular dystrophy

scientific article

Laminin-111 restores regenerative capacity in a mouse model for alpha7 integrin congenital myopathy

scientific article published on 12 December 2008

Levels of α7 integrin and laminin-α2 are increased following prednisone treatment in the mdx mouse and GRMD dog models of Duchenne muscular dystrophy

scientific article published on 11 July 2013

Localization and genomic organization of sheep antimicrobial peptide genes ⬇️

scientific article published on January 5, 1998

Localization of the human indoleamine 2,3-dioxygenase (IDO) gene to the pericentromeric region of human chromosome 8

scientific article

Loss of the 7 Integrin Promotes Extracellular Signal-Regulated Kinase Activation and Altered Vascular Remodeling

Mapping the sheep genome: production of characterized sheep x hamster cell hybrids

scientific article published on 01 May 1993

Mapping, sequence, and expression analysis of the human fertilin beta gene (FTNB).

scientific article

Mesothelioma cells breaking bad: loss of integrin α7 promotes cell motility and poor clinical outcomes in patients

scientific article

New gene assignments using a complete, characterized sheep‐hamster somatic cell hybrid panel ⬇️

scientific article published on February 1, 1998

PTRH2 gene mutation causes progressive congenital skeletal muscle pathology

scientific article

Physical assignment of loci to sheep chromosome 7 confirms its homology to cattle chromosome 10

scientific article published on 01 October 1995

Placental defects in alpha7 integrin null mice

scientific article

Regional assignment of the neurotensin locus in sheep

scientific article published on 01 September 1993

Report on the Myomatrix Conference April 22-24, 2012, University of Nevada, Reno, Nevada, USA

scientific article published on 15 July 2012

Role for the alpha7beta1 integrin in vascular development and integrity

scientific journal article

SU9516 Increases α7β1 Integrin and Ameliorates Disease Progression in the mdx Mouse Model of Duchenne Muscular Dystrophy

scientific article published on 5 April 2017

Sarcospan integration into laminin-binding adhesion complexes that ameliorate muscular dystrophy requires utrophin and α7 integrin

scientific article

Seven loci on human chromosome 4 map onto sheep chromosome 6: a proposal to restore the original nomenclature of this sheep chromosome

scientific article published in July 1994

Severe muscular dystrophy in mice that lack dystrophin and alpha7 integrin

scientific article published on 09 May 2006

Sheep CENPB and CENPC genes show a high level of sequence similarity and conserved synteny with their human homologs

scientific article published on January 1996

The alpha7beta1 integrin in muscle development and disease

scientific article

The chromosomal distribution and organization of sheep satellite I and II centromeric DNA using characterized sheep-hamster somatic cell hybrids

scientific article published in January 1996

The gene for the serpin thrombin inhibitor (PI7), protease nexin I, is located on human chromosome 2q33-q35 and on syntenic regions in the mouse and sheep genomes

scientific article

The muscle integrin binding protein (MIBP) interacts with alpha7beta1 integrin and regulates cell adhesion and laminin matrix deposition

scientific article

Thirteen loci physically assigned to sheep chromosome 2 by cell hybrid analysis and in situ hybridization

scientific article published on 01 December 1995

Transgenic expression of {alpha}7{beta}1 integrin maintains muscle integrity, increases regenerative capacity, promotes hypertrophy, and reduces cardiomyopathy in dystrophic mice

scientific article

Transgenic overexpression of the α7 integrin reduces muscle pathology and improves viability in the dy(W) mouse model of merosin-deficient congenital muscular dystrophy type 1A.

scientific article published on 7 June 2011

Use of the Indian muntjac idiogram to align conserved chromosomal segments in sheep and human genomes by chromosome painting

scientific article

Valproic acid activates the PI3K/Akt/mTOR pathway in muscle and ameliorates pathology in a mouse model of Duchenne muscular dystrophy

scientific article published on 29 January 2009

List of works by Dean Burkin

A functional role for specific spliced variants of the alpha7beta1 integrin in acetylcholine receptor clustering

A molecular bandage for diseased muscle

Activation of AKT signaling promotes cell growth and survival in α7β1 integrin-mediated alleviation of muscular dystrophy

Activation of volume regulated chloride channels protects myocardium from ischemia/reperfusion damage in second-window ischemic preconditioning.

Alpha 7 integrin preserves the function of the extensor digitorum longus muscle in dystrophin-null mice

Alpha7beta1-integrin regulates mechanotransduction and prevents skeletal muscle injury

Bit-1 is an essential regulator of myogenic differentiation

Cardiac-specific, inducible ClC-3 gene deletion eliminates native volume-sensitive chloride channels and produces myocardial hypertrophy in adult mice

Diagnosis and etiology of congenital muscular dystrophy

Dystrophin and utrophin expression require sarcospan: loss of α7 integrin exacerbates a newly discovered muscle phenotype in sarcospan-null mice

ECM-Related Myopathies and Muscular Dystrophies: Pros and Cons of Protein Therapies

Enhanced expression of the alpha 7 beta 1 integrin reduces muscular dystrophy and restores viability in dystrophic mice

Evaluation of the behavioral characteristics of the mdx mouse model of duchenne muscular dystrophy through operant conditioning procedures

Exercise promotes alpha7 integrin gene transcription and protection of skeletal muscle

Four human chromosome 3q and four human chromosome 21 loci map onto sheep chromosome 1q

Four loci from human chromosome 1 are physically assigned to sheep chromosome 1p

Galectin-1 Protein Therapy Prevents Pathology and Improves Muscle Function in the mdx Mouse Model of Duchenne Muscular Dystrophy

Heart-specific overexpression of the human short CLC-3 chloride channel isoform limits myocardial ischemia-induced ERP and QT prolongation

Human laminin-111 and laminin-211 protein therapy prevents muscle disease progression in an immunodeficient mouse model of LAMA2-CMD

Impaired fetal muscle development and JAK-STAT activation mark disease onset and progression in a mouse model for merosin-deficient congenital muscular dystrophy

Improving Reproducibility of Phenotypic Assessments in the DyW Mouse Model of Laminin-α2 Related Congenital Muscular Dystrophy

Increasing alpha 7 beta 1-integrin promotes muscle cell proliferation, adhesion, and resistance to apoptosis without changing gene expression

Integrin α7: a major driver and therapeutic target for glioblastoma malignancy

Isolation of chromosome-specific paints from high-resolution flow karyotypes of the sheep (Ovis aries).

Laminin and alpha7beta1 integrin regulate agrin-induced clustering of acetylcholine receptors

Laminin-111 improves muscle repair in a mouse model of merosin-deficient congenital muscular dystrophy

Laminin-111 protein therapy prevents muscle disease in the mdx mouse model for Duchenne muscular dystrophy

Laminin-111 protein therapy reduces muscle pathology and improves viability of a mouse model of merosin-deficient congenital muscular dystrophy

Laminin-111 restores regenerative capacity in a mouse model for alpha7 integrin congenital myopathy

Levels of α7 integrin and laminin-α2 are increased following prednisone treatment in the mdx mouse and GRMD dog models of Duchenne muscular dystrophy

Localization and genomic organization of sheep antimicrobial peptide genes ⬇️

Localization of the human indoleamine 2,3-dioxygenase (IDO) gene to the pericentromeric region of human chromosome 8

Loss of the 7 Integrin Promotes Extracellular Signal-Regulated Kinase Activation and Altered Vascular Remodeling

Mapping the sheep genome: production of characterized sheep x hamster cell hybrids

Mapping, sequence, and expression analysis of the human fertilin beta gene (FTNB).

Mesothelioma cells breaking bad: loss of integrin α7 promotes cell motility and poor clinical outcomes in patients

New gene assignments using a complete, characterized sheep‐hamster somatic cell hybrid panel ⬇️

PTRH2 gene mutation causes progressive congenital skeletal muscle pathology

Physical assignment of loci to sheep chromosome 7 confirms its homology to cattle chromosome 10

Placental defects in alpha7 integrin null mice

Regional assignment of the neurotensin locus in sheep

Report on the Myomatrix Conference April 22-24, 2012, University of Nevada, Reno, Nevada, USA

Role for the alpha7beta1 integrin in vascular development and integrity

SU9516 Increases α7β1 Integrin and Ameliorates Disease Progression in the mdx Mouse Model of Duchenne Muscular Dystrophy

Sarcospan integration into laminin-binding adhesion complexes that ameliorate muscular dystrophy requires utrophin and α7 integrin

Seven loci on human chromosome 4 map onto sheep chromosome 6: a proposal to restore the original nomenclature of this sheep chromosome

Severe muscular dystrophy in mice that lack dystrophin and alpha7 integrin

Sheep CENPB and CENPC genes show a high level of sequence similarity and conserved synteny with their human homologs

The alpha7beta1 integrin in muscle development and disease

The chromosomal distribution and organization of sheep satellite I and II centromeric DNA using characterized sheep-hamster somatic cell hybrids

The gene for the serpin thrombin inhibitor (PI7), protease nexin I, is located on human chromosome 2q33-q35 and on syntenic regions in the mouse and sheep genomes

The muscle integrin binding protein (MIBP) interacts with alpha7beta1 integrin and regulates cell adhesion and laminin matrix deposition

Thirteen loci physically assigned to sheep chromosome 2 by cell hybrid analysis and in situ hybridization

Transgenic expression of {alpha}7{beta}1 integrin maintains muscle integrity, increases regenerative capacity, promotes hypertrophy, and reduces cardiomyopathy in dystrophic mice

Transgenic overexpression of the α7 integrin reduces muscle pathology and improves viability in the dy(W) mouse model of merosin-deficient congenital muscular dystrophy type 1A.

Use of the Indian muntjac idiogram to align conserved chromosomal segments in sheep and human genomes by chromosome painting

Valproic acid activates the PI3K/Akt/mTOR pathway in muscle and ameliorates pathology in a mouse model of Duchenne muscular dystrophy