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List of works by Richard J. Hodes

A novel T cell subset with trans-rearranged Vγ-Cβ TCRs shows Vβ expression is dispensable for lineage choice and MHC restriction

scientific article

A novel role for CD28 in thymic selection: elimination of CD28/B7 interactions increases positive selection

scientific article published on 01 February 2005

ATM Influences the Efficiency of TCRβ Rearrangement, Subsequent TCRβ-Dependent T Cell Development, and Generation of the Pre-Selection TCRβ CDR3 Repertoire ⬇️

scientific article published on April 23, 2013

ATM deficiency impairs thymocyte maturation because of defective resolution of T cell receptor alpha locus coding end breaks

scholarly article

ATM deficiency promotes development of murine B-cell lymphomas that resemble diffuse large B-cell lymphoma in humans

scientific article

Ablation of Cbl-b provides protection against transplanted and spontaneous tumors

scientific article published on 15 March 2007

Abnormal differentiation of memory T cells in systemic lupus erythematosus

scientific article published on 01 July 2006

Accelerating Medicines Partnership: Alzheimer's Disease (AMP-AD) Knowledge Portal Aids Alzheimer's Drug Discovery through Open Data Sharing

scientific article published on 7 February 2016

Age-associated telomere attrition of lymphocytes in vivo is co-ordinated with changes in telomerase activity, composition of lymphocyte subsets and health conditions

scientific article

Aging Research: Collaborations Forge a Promising Future

scientific article published on 30 August 2017

Aging in the context of immunological architecture, function and disease outcomes

scientific article published on 21 June 2009

Analysis of telomere length and telomerase activity

scientific article published on September 2004

Apex of deformity for three-column osteotomy. Does it matter in the occurrence of complications?

scientific article published on 9 July 2015

Basic science: Bedrock of progress

scientific article published on March 2016

Both telomeric and non-telomeric DNA damage are determinants of mammalian cellular senescence

scientific article

CD28 costimulation is required for in vivo induction of peripheral tolerance in CD8 T cells

scientific article

CD28-CD80/86 and CD40-CD40L Interactions Promote Thymic Tolerance by Regulating Medullary Epithelial Cell and Thymocyte Development

scientific article

CD40 ligand functions non-cell autonomously to promote deletion of self-reactive thymocytes

scientific article published on 01 March 2002

Cbl Enforces Vav1 Dependence and a Restricted Pathway of T Cell Development ⬇️

scientific article published on April 7, 2011

Cbl enforces an SLP76-dependent signaling pathway for T cell differentiation

scientific article published on 11 December 2008

Co-stimulatory function in primary germinal center responses: CD40 and B7 are required on distinct antigen-presenting cells.

scientific article

Concurrent V(D)J recombination and DNA end instability increase interchromosomal trans -rearrangements in ATM-deficient thymocytes ⬇️

scientific article published on March 6, 2013

Decreased glucocerebrosidase activity in Gaucher disease parallels quantitative enzyme loss due to abnormal interaction with TCP1 and c-Cbl.

scientific article

Differential cis-regulation of human versus mouse TERT gene expression in vivo: identification of a human-specific repressive element

scientific article

Differential requirements for expression of CD80/86 and CD40 on B cells for T-dependent antibody responses in vivo

scientific article

Disease drivers of aging

scientific article published on December 2016

Don't forget to prescribe exercise for your older patients

scientific article published on 01 October 2004

Downmodulation of tumor suppressor p53 by T cell receptor signaling is critical for antigen-specific CD4(+) T cell responses

scientific article

Dynamic equilibrium of B7-1 dimers and monomers differentially affects immunological synapse formation and T cell activation in response to TCR/CD28 stimulation

scientific article

Editorial overview

scientific article published on 23 July 2012

Epidemiology, comparative effectiveness research, and the National Institutes of Health: forces for health

scientific article

Exon 1 disruption alters tissue-specific expression of mouse p53 and results in selective development of B cell lymphomas

scientific article

Expression of telomerase RNA template, but not telomerase reverse transcriptase, is limiting for telomere length maintenance in vivo

scientific article published on August 2004

Eyes on the prize: federal Alzheimer's research effort aims to facilitate interventions

scientific article published on 21 December 2007

Fetal expression of Fas ligand is necessary and sufficient for induction of CD8 T cell tolerance to the fetal antigen H-Y during pregnancy

scientific article published on 01 April 2005

Generation and characterization of telomere length maintenance in tankyrase 2-deficient mice

scientific article

Getting it right: being smarter about clinical trials

scientific article (publication date: April 2006)

Haploinsufficiency of mTR results in defects in telomere elongation

scientific article

Immunoglobulin class switch recombination is impaired in Atm-deficient mice

scientific article

In vivo regulation of telomerase activity and telomere length

scientific article

Inactivation of c-Cbl or Cbl-b differentially affects signaling from the high affinity IgE receptor

scientific article

Inactivation of c-Cbl reverses neonatal lethality and T cell developmental arrest of SLP-76-deficient mice

scientific article

Induction of telomerase activity and maintenance of telomere length in virus-specific effector and memory CD8+ T cells

scientific article published in January 2003

Inhibition of serine/threonine phosphatase PP2A enhances cancer chemotherapy by blocking DNA damage induced defense mechanisms

scientific article published on 29 June 2009

Investigating the Universality of Preoperative Health-Related Quality of Life (HRQoL) for Surgically Treated Spinal Deformity in Young Adults: A Propensity Score-Matched Comparison Between African and US Populations

scientific article published on 21 August 2016

Loss of Dact1 disrupts planar cell polarity signaling by altering dishevelled activity and leads to posterior malformation in mice

scientific journal article

NIA commentary on the NIA-AA Research Framework: Towards a biological definition of Alzheimer's disease

scientific article published on 01 April 2018

National Institute on Aging at Middle Age—Its Past, Present, and Future ⬇️

scientific article published on May 30, 2012

National Institute on Aging. Interview by Vicki Glaser

scientific article published in January 2006

Neuroethics for the National Institutes of Health BRAIN Initiative

article

Persistence of tumor infiltrating lymphocytes in adoptive immunotherapy correlates with telomere length.

scientific article

Prohibitins and the cytoplasmic domain of CD86 cooperate to mediate CD86 signaling in B lymphocytes.

scientific article published on 12 December 2012

Prospects for life span extension

scientific article published on January 2009

Public funding for Alzheimer disease research in the United States

scientific article

RAG-mediated V(D)J recombination is not essential for tumorigenesis in Atm-deficient mice

scientific article

Redundancy in B cell developmental pathways: c-Cbl inactivation rescues early B cell development through a B cell linker protein-independent pathway

scientific journal article

Regulated costimulation in the thymus is critical for T cell development: dysregulated CD28 costimulation can bypass the pre-TCR checkpoint

scientific article

Regulation of T cell development by c-Cbl: essential role of Lck.

scientific article published on 4 December 2014

Regulation of thymic NKT cell development by the B7-CD28 costimulatory pathway

scientific article published on July 2008

Response to: "Rescuing the NIH before it is too late".

scientific article published on June 2006

Stepwise differentiation of CD4 memory T cells defined by expression of CCR7 and CD27.

scientific article published in November 2005

T cell-B cell thymic cross-talk: maintenance and function of thymic B cells requires cognate CD40-CD40 ligand interaction

scientific article

T-cell development is regulated by the coordinated function of proximal and distal Lck promoters active at different developmental stages

scientific article published on 29 July 2016

TCR Repertoires of Thymic Conventional and Regulatory T Cells: Identification and Characterization of Both Unique and Shared TCR Sequences

scientific article published on 10 January 2020

Tankyrase 1 and tankyrase 2 are essential but redundant for mouse embryonic development

scientific article

Telomere Shortening, Inflammatory Cytokines, and Anti-Cytomegalovirus Antibody Follow Distinct Age-Associated Trajectories in Humans.

scientific article published on 24 August 2017

Telomere biology and immune system.

scientific article published in June 2005

Telomere length is inherited with resetting of the telomere set-point.

scientific article

Telomere length of transferred lymphocytes correlates with in vivo persistence and tumor regression in melanoma patients receiving cell transfer therapy.

scientific article

Telomere-associated protein TIN2 is essential for early embryonic development through a telomerase-independent pathway

scientific article published on August 2004

Telomeres in T and B cells

scientific article

The NIH Blueprint for Neuroscience Research Seeks Community Input on Future Neuroscience Investments

scientific article published on 01 January 2019

The NIH toolbox: setting a standard for biomedical research

scientific article published on March 2013

The Requirement for Pre-TCR during Thymic Differentiation Enforces a Developmental Pause That Is Essential for V-DJβ Rearrangement ⬇️

scientific article published on June 3, 2011

The effects of aging on lymphocyte development and function: introduction

scientific article published on 01 January 2002

The future of aging therapies

scientific article

Thymic medullary epithelium and thymocyte self-tolerance require cooperation between CD28-CD80/86 and CD40-CD40L costimulatory pathways

scientific article published on 13 December 2013

Transcriptome analysis of mouse stem cells and early embryos

scientific article

Visiting Solomon: AIDS in Ethiopia ⬇️

scientific article published on 01 January 2002

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