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List of works by Loredana Saveanu

A detailed analysis of the murine TAP transporter substrate specificity

scientific article

A long N-terminal-extended nested set of abundant and antigenic major histocompatibility complex class I natural ligands from HIV envelope protein

scientific article published on 6 January 2006

A proteasome-dependent, TAP-independent pathway for cross-presentation of phagocytosed antigen.

scientific article published on December 2011

Altered expression of endoplasmic reticulum aminopeptidases ERAP1 and ERAP2 in transformed non-lymphoid human tissues

scientific article

Analysis of direct and cross-presentation of antigens in TPPII knockout mice

scientific article published in December 2007

Beyond the proteasome: trimming, degradation and generation of MHC class I ligands by auxiliary proteases

scientific article

Complexity, contradictions, and conundrums: studying post-proteasomal proteolysis in HLA class I antigen presentation.

scientific article

Concerted peptide trimming by human ERAP1 and ERAP2 aminopeptidase complexes in the endoplasmic reticulum.

scientific article published on 22 May 2005

Conventional dendritic cells require IRAP-Rab14 endosomes for efficient cross-presentation

scientific article published on 11 January 2012

Cross-Presentation of Cell-Associated Antigens by MHC Class I in Dendritic Cell Subsets

scientific article (publication date: 2015)

Dendritic cells: open for presentation business

scientific article published on 01 January 2005

Differential proteasomal processing of hydrophobic and hydrophilic protein regions: contribution to cytotoxic T lymphocyte epitope clustering in HIV-1-Nef.

scientific article

Distinct functions of the ATP binding cassettes of transporters associated with antigen processing: a mutational analysis of Walker A and B sequences

scientific article published on 4 April 2001

ER-phagosome fusion defines an MHC class I cross-presentation compartment in dendritic cells

scientific journal article

ERAP1-ERAP2 dimerization increases peptide-trimming efficiency.

scientific article published on 13 June 2014

Ex vivo characterization of multiepitopic tumor-specific CD8 T cells in patients with chronic myeloid leukemia: implications for vaccine development and adoptive cellular immunotherapy

scientific article published in June 2005

IRAP identifies an endosomal compartment required for MHC class I cross-presentation

scientific journal article

IRAP+ endosomes restrict TLR9 activation and signaling

scientific article

IRAP-dependent endosomal T cell receptor signalling is essential for T cell responses

scientific article published on 02 June 2020

Impact of the TAP-like transporter in antigen presentation and phagosome maturation

scientific article published on 23 June 2018

Innate Immune Signals Induce Anterograde Endosome Transport Promoting MHC Class I Cross-Presentation

scientific article published on 01 September 2018

Insulin-regulated aminopeptidase and its compartment in dendritic cells.

scientific article

Intracellular Transport Routes for MHC I and Their Relevance for Antigen Cross-Presentation

scientific article (publication date: 2015)

LC3-associated phagocytosis protects against inflammation and liver fibrosis via immunoreceptor inhibitory signaling

scientific article published on 01 April 2020

New pieces in the complex puzzle of aberrant vacuolation. Focus on "Active vacuolar H+ ATPase and functional cycle of Rab5 are required for the vacuolation defect triggered by PtdIns(3,5)P2 loss under PIKfyve or Vps34 deficiency".

scientific article published on 3 August 2016

Novel selective inhibitors of aminopeptidases that generate antigenic peptides.

scientific article published on 23 July 2013

Pancreatic β-Cells Limit Autoimmune Diabetes via an Immunoregulatory Antimicrobial Peptide Expressed under the Influence of the Gut Microbiota.

scientific article published on 3 August 2015

Peptidases trimming MHC class I ligands

scientific article published on 19 October 2012

Powering the peptide pump: TAP crosstalk with energetic nucleotides

scientific article published in September 2002

Preparing Antigens Suitable for Cross-presentation Assays In Vitro and In Vivo ⬇️

scientific article published on 01 January 2013

Quantifying recruitment of cytosolic peptides for HLA class I presentation: impact of TAP transport

scientific article published on March 2003

Regulation of transporters associated with antigen processing (TAPs) by nucleotide binding to, and hydrolysis by, Walker consensus sequences ⬇️

scientific article published on 01 January 2001

The Isoform Selective Roles of PI3Ks in Dendritic Cell Biology and Function

scientific article published on 15 November 2018

The role of endoplasmic reticulum-associated aminopeptidase 1 in immunity to infection and in cross-presentation

scientific article published on 01 February 2007

The role of insulin-regulated aminopeptidase in MHC class I antigen presentation

scientific article published on 21 March 2012

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