List of works - Jun Chang

A Single-Amino-Acid Variant of the H60 CD8 Epitope Generates Specific Immunity with Diverse TCR Recruitment ⬇️

scientific article published on March 21, 2012

A protein transduction domain located at the NH2-terminus of human translationally controlled tumor protein for delivery of active molecules to cells.

scientific article published on 22 September 2010

Antiviral activity of carnosic acid against respiratory syncytial virus

scientific article published on 8 October 2013

Baculovirus Displaying Hemagglutinin Elicits Broad Cross-Protection against Influenza in Mice

scientific article

Challenges in the development of T-cell-based universal influenza vaccines.

scientific article published on 25 January 2017

Cholera Toxin Promotes Th17 Cell Differentiation by Modulating Expression of Polarizing Cytokines and the Antigen-Presenting Potential of Dendritic Cells

scientific article

Co-transplantation of human fetal thymus, bone and CD34(+) cells into young adult immunodeficient NOD/SCID IL2Rγ(null) mice optimizes humanized mice that mount adaptive antibody responses

scientific article published on 25 February 2015

Cooperative transformation of murine fibroblast NIH3T3 cells by hepatitis C virus core protein and hepatitis B virus X protein.

scientific article published on August 2003

Current progress on development of respiratory syncytial virus vaccine.

scientific article published on April 2011

Development of safe and effective RSV vaccine by modified CD4 epitope in G protein core fragment (Gcf).

scientific article

Differentiation of Antigen-Specific T Cells with Limited Functional Capacity during Mycobacterium tuberculosis Infection.

scientific article published in August 2014

Differentiation of antigen-specific T cells with limited functional capacity during Mycobacterium tuberculosis infection

scientific article published on 14 October 2013

Discrimination between active and latent tuberculosis based on ratio of antigen-specific to mitogen-induced IP-10 production

scientific article

Dual role of respiratory syncytial virus glycoprotein fragment as a mucosal immunogen and chemotactic adjuvant

scientific article

Effect of respiratory syncytial virus on the growth of hepatocellular carcinoma cell-lines

scientific article published on 05 March 2015

Efficient induction of T helper 1 CD4+ T-cell responses to hepatitis C virus core and E2 by a DNA prime-adenovirus boost.

scientific article published on November 2003

Engineering N-glycosylation mutations in IL-12 enhances sustained cytotoxic T lymphocyte responses for DNA immunization.

scientific article

Escape from thymic deletion and anti-leukemic effects of T cells specific for hematopoietic cell-restricted antigen.

scientific article published on 15 January 2018

Evaluation of protective efficacy of respiratory syncytial virus vaccine against A and B subgroup human isolates in Korea

scientific article

Hepatitis C virus core protein promotes cell proliferation through the upregulation of cyclin E expression levels.

scientific article published on April 2001

In Hot Pursuit of the First Vaccine Against Respiratory Syncytial Virus

scientific article

In vivo imaging of differences in early donor cell proliferation in graft-versus-host disease hosts with different pre-conditioning doses.

scientific article published on 03 January 2012

Induction of long-term immunity against respiratory syncytial virus glycoprotein by an osmotic polymeric nanocarrier.

scientific article

Intranasal adenovirus-vectored vaccine for induction of long-lasting humoral immunity-mediated broad protection against influenza in mice

scientific article

Intranasal delivery of cholera toxin induces th17-dominated T-cell response to bystander antigens

scientific article

Local Structural Elements in the Mostly Unstructured Transcriptional Activation Domain of Human p53

scientific article published in Journal of Biological Chemistry

Memory programming in CD8(+) T-cell differentiation is intrinsic and is not determined by CD4 help

scientific article

Monoclonal Antibody against G Glycoprotein Increases Respiratory Syncytial Virus Clearance In Vivo and Prevents Vaccine-Enhanced Diseases

scientific article

Mucosal vaccination with recombinant adenovirus encoding nucleoprotein provides potent protection against influenza virus infection

scientific article

Nucleoprotein vaccine induces cross-protective cytotoxic T lymphocytes against both lineages of influenza B virus

scientific article published on 31 January 2019

PD-1 upregulated on regulatory T cells during chronic virus infection enhances the suppression of CD8+ T cell immune response via the interaction with PD-L1 expressed on CD8+ T cells.

scientific article published on May 2015

Phenotypic changes induced by IL-12 priming regulate effector and memory CD8 T cell differentiation.

scientific article published on 6 September 2007

Respiratory syncytial virus infection suppresses lung CD8+ T-cell effector activity and peripheral CD8+ T-cell memory in the respiratory tract

scientific article

Single mucosal immunization of recombinant adenovirus-based vaccine expressing F1 protein fragment induces protective mucosal immunity against respiratory syncytial virus infection.

scientific article published on 31 March 2010

Sublingual immunization with Japanese encephalitis virus vaccine effectively induces immunity through both cellular and humoral immune responses in mice

scientific article published on 22 December 2016

Sublingual immunization with recombinant adenovirus encoding SARS-CoV spike protein induces systemic and mucosal immunity without redirection of the virus to the brain.

scientific article

Superior immune responses induced by intranasal immunization with recombinant adenovirus-based vaccine expressing full-length Spike protein of Middle East respiratory syndrome coronavirus

scientific article published on 22 July 2019

Systemic analysis of heat shock response induced by heat shock and a proteasome inhibitor MG132

scientific article

Systemic human T cell developmental processes in humanized mice cotransplanted with human fetal thymus/liver tissue and hematopoietic stem cells.

scientific article published on December 2012

TCR diversity of H60-specific CD8 T cells during the response evolution and influence of CD4 help.

scientific article

Transplantation of human spleen into immunodeficient NOD/SCID IL2Rγ(null) mice generates humanized mice that improve functional B cell development

scientific article published on 7 September 2015

Universal vaccine against respiratory syncytial virus A and B subtypes

scientific article

Vaccine containing G protein fragment and recombinant baculovirus expressing M2 protein induces protective immunity to respiratory syncytial virus

scientific article published on 31 January 2019

List of works by Jun Chang

A Single-Amino-Acid Variant of the H60 CD8 Epitope Generates Specific Immunity with Diverse TCR Recruitment ⬇️

A protein transduction domain located at the NH2-terminus of human translationally controlled tumor protein for delivery of active molecules to cells.

Antiviral activity of carnosic acid against respiratory syncytial virus

Baculovirus Displaying Hemagglutinin Elicits Broad Cross-Protection against Influenza in Mice

Challenges in the development of T-cell-based universal influenza vaccines.

Cholera Toxin Promotes Th17 Cell Differentiation by Modulating Expression of Polarizing Cytokines and the Antigen-Presenting Potential of Dendritic Cells

Co-transplantation of human fetal thymus, bone and CD34(+) cells into young adult immunodeficient NOD/SCID IL2Rγ(null) mice optimizes humanized mice that mount adaptive antibody responses

Cooperative transformation of murine fibroblast NIH3T3 cells by hepatitis C virus core protein and hepatitis B virus X protein.

Current progress on development of respiratory syncytial virus vaccine.

Development of safe and effective RSV vaccine by modified CD4 epitope in G protein core fragment (Gcf).

Differentiation of Antigen-Specific T Cells with Limited Functional Capacity during Mycobacterium tuberculosis Infection.

Differentiation of antigen-specific T cells with limited functional capacity during Mycobacterium tuberculosis infection

Discrimination between active and latent tuberculosis based on ratio of antigen-specific to mitogen-induced IP-10 production

Dual role of respiratory syncytial virus glycoprotein fragment as a mucosal immunogen and chemotactic adjuvant

Effect of respiratory syncytial virus on the growth of hepatocellular carcinoma cell-lines

Efficient induction of T helper 1 CD4+ T-cell responses to hepatitis C virus core and E2 by a DNA prime-adenovirus boost.

Engineering N-glycosylation mutations in IL-12 enhances sustained cytotoxic T lymphocyte responses for DNA immunization.

Escape from thymic deletion and anti-leukemic effects of T cells specific for hematopoietic cell-restricted antigen.

Evaluation of protective efficacy of respiratory syncytial virus vaccine against A and B subgroup human isolates in Korea

Hepatitis C virus core protein promotes cell proliferation through the upregulation of cyclin E expression levels.

In Hot Pursuit of the First Vaccine Against Respiratory Syncytial Virus

In vivo imaging of differences in early donor cell proliferation in graft-versus-host disease hosts with different pre-conditioning doses.

Induction of long-term immunity against respiratory syncytial virus glycoprotein by an osmotic polymeric nanocarrier.

Intranasal adenovirus-vectored vaccine for induction of long-lasting humoral immunity-mediated broad protection against influenza in mice

Intranasal delivery of cholera toxin induces th17-dominated T-cell response to bystander antigens

Local Structural Elements in the Mostly Unstructured Transcriptional Activation Domain of Human p53

Memory programming in CD8(+) T-cell differentiation is intrinsic and is not determined by CD4 help

Monoclonal Antibody against G Glycoprotein Increases Respiratory Syncytial Virus Clearance In Vivo and Prevents Vaccine-Enhanced Diseases

Mucosal vaccination with recombinant adenovirus encoding nucleoprotein provides potent protection against influenza virus infection

Nucleoprotein vaccine induces cross-protective cytotoxic T lymphocytes against both lineages of influenza B virus

PD-1 upregulated on regulatory T cells during chronic virus infection enhances the suppression of CD8+ T cell immune response via the interaction with PD-L1 expressed on CD8+ T cells.

Phenotypic changes induced by IL-12 priming regulate effector and memory CD8 T cell differentiation.

Respiratory syncytial virus infection suppresses lung CD8+ T-cell effector activity and peripheral CD8+ T-cell memory in the respiratory tract

Single mucosal immunization of recombinant adenovirus-based vaccine expressing F1 protein fragment induces protective mucosal immunity against respiratory syncytial virus infection.

Sublingual immunization with Japanese encephalitis virus vaccine effectively induces immunity through both cellular and humoral immune responses in mice

Sublingual immunization with recombinant adenovirus encoding SARS-CoV spike protein induces systemic and mucosal immunity without redirection of the virus to the brain.

Superior immune responses induced by intranasal immunization with recombinant adenovirus-based vaccine expressing full-length Spike protein of Middle East respiratory syndrome coronavirus

Systemic analysis of heat shock response induced by heat shock and a proteasome inhibitor MG132

Systemic human T cell developmental processes in humanized mice cotransplanted with human fetal thymus/liver tissue and hematopoietic stem cells.

TCR diversity of H60-specific CD8 T cells during the response evolution and influence of CD4 help.

Transplantation of human spleen into immunodeficient NOD/SCID IL2Rγ(null) mice generates humanized mice that improve functional B cell development

Universal vaccine against respiratory syncytial virus A and B subtypes

Vaccine containing G protein fragment and recombinant baculovirus expressing M2 protein induces protective immunity to respiratory syncytial virus