List of works - Sofie Demeyer

A palmitate-rich metastatic niche enables metastasis growth via p65 acetylation resulting in pro-metastatic NF-κB signaling

scientific article published in 2023

BCR-ABL1 positive B-ALL can undergo T-cell lineage shift to become CD19 negative T-ALL

scientific article published on 19 April 2018

Defining the molecular basis of oncogenic cooperation between TAL1 expression and Pten deletion in T-ALL using a novel pro-T-cell model system.

scientific article published on 20 November 2017

Deletions of the long arm of chromosome 5 define subgroups of T-cell acute lymphoblastic leukemia

scientific article published on 05 May 2016

Generation of the Fip1l1-Pdgfra fusion gene using CRISPR/Cas genome editing

scientific article published on 8 March 2016

HOXA9 cooperates with activated JAK/STAT signaling to drive leukemia development.

scientific article published in March 2018

Hedgehog pathway activation in T-cell acute lymphoblastic leukemia predicts response to SMO and GLI1 inhibitors

scientific article

JAK3 mutants transform hematopoietic cells through JAK1 activation, causing T-cell acute lymphoblastic leukemia in a mouse model

scientific article (publication date: 5 September 2014)

Mutant JAK3 phosphoproteomic profiling predicts synergism between JAK3 inhibitors and MEK/BCL2 inhibitors for the treatment of T-cell acute lymphoblastic leukemia.

scientific article published on 30 August 2017

Mutant JAK3 signaling is increased by loss of wild type JAK3 or by acquiring secondary JAK3 mutations in T-ALL.

scientific article published on 29 November 2017

Oncogenic cooperation between TCF7-SPI1 and NRAS(G12D) requires β-catenin activity to drive T-cell acute lymphoblastic leukemia

scientific article published on 06 July 2021

Overexpression of wild-type IL-7Rα promotes T-cell acute lymphoblastic leukemia/lymphoma

scientific article published on 01 September 2021

PHGDH heterogeneity potentiates cancer cell dissemination and metastasis

scientific article published in 2022

RNA sequencing unravels the genetics of refractory/relapsed T-cell acute lymphoblastic leukemia. Prognostic and therapeutic implications

scientific article published on 05 May 2016

Safe targeting of T cell acute lymphoblastic leukemia by pathology-specific NOTCH inhibition

scientific article published on 01 May 2019

Single-cell sequencing reveals the origin and the order of mutation acquisition in T-cell acute lymphoblastic leukemia.