Search filters

List of works by Ling Peng

19F NMR: a valuable tool for studying biological events.

scientific article published on October 2013

2-Difluoromethylene-4-methylenepentanoic Acid, A Paradoxical Probe Able To Mimic the Signaling Role of 2-Oxoglutaric Acid in Cyanobacteria

scientific article published on 05 May 2011

2-Nitrobenzylarsonium Compounds That Photorelease Heavy-Atom Cholinergic Ligands for Time-Resolved Crystallographic Studies on Cholinesterases

scientific article published on 01 October 1998

A "click" chemistry constructed affinity system for 2-oxoglutaric acid receptors and binding proteins

scientific article published on 01 September 2014

A bola-phospholipid bearing tetrafluorophenylazido chromophore as a promising lipid probe for biomembrane photolabeling studies.

scientific article published on 20 June 2013

A dual targeting dendrimer-mediated siRNA delivery system for effective gene silencing in cancer therapy

article

A novel arylethynyltriazole acyclonucleoside inhibits proliferation of drug-resistant pancreatic cancer cells.

scientific article published on 21 August 2010

A novel bitriazolyl acyclonucleoside endowed with dual antiproliferative and immunomodulatory activity

scientific article published on 21 May 2012

A self-assembling amphiphilic dendrimer nanotracer for SPECT imaging

scientific article published on 01 December 2019

Adaptive amphiphilic dendrimer-based nanoassemblies as robust and versatile siRNA delivery systems

scientific article published on 12 September 2014

Amphiphilic Dendrimer Vectors for RNA Delivery: State-of-the-Art and Future Perspective

scientific article published in 2022

An amphiphilic dendrimer for effective delivery of small interfering RNA and gene silencing in vitro and in vivo

scientific article published on 24 July 2012

An efficient mixed-ligand Pd catalytic system to promote C-N coupling for the synthesis of N-arylaminotriazole nucleosides

scientific article published on 20 January 2012

Anticancer drug nanomicelles formed by self-assembling amphiphilic dendrimer to combat cancer drug resistance.

scientific article

Arginine-terminated generation 4 PAMAM dendrimer as an effective nanovector for functional siRNA delivery in vitro and in vivo

scientific article published on 11 February 2014

Arylethynyltriazole acyclonucleosides inhibit hepatitis C virus replication

scientific article published on 15 April 2008

Biochemical Evaluation of Photolabile Precursors of Choline and of Carbamylcholine for Potential Time-Resolved Crystallographic Studies on Cholinesterases†

scientific article published on 01 August 1996

Bitriazolyl acyclonucleosides synthesized via Huisgen reaction using internal alkynes show antiviral activity against tobacco mosaic virus.

scientific article published on 5 November 2010

Blocking Stemness and Metastatic Properties of Ovarian Cancer Cells by Targeting p70S6K with Dendrimer Nanovector-Based siRNA Delivery.

scientific article published on 16 November 2017

C-S coupling using a mixed-ligand Pd catalyst: a highly effective strategy for synthesizing arylthio-substituted heterocycles.

scientific article

Carbon/Nitrogen Metabolic Balance: Lessons from Cyanobacteria

scientific article published on 03 October 2018

Cooperative binding and self-assembling behavior of cationic low molecular-weight dendrons with RNA molecules.

scientific article published on 9 January 2006

Copper(ii) binding to flexible triethanolamine-core PAMAM dendrimers: a combined experimental/in silico approach

scientific article published on 01 January 2014

Designing and repurposing drugs to target intrinsically disordered proteins for cancer treatment: using NUPR1 as a paradigm

scientific article published on 16 May 2019

Discovery of novel arylethynyltriazole ribonucleosides with selective and effective antiviral and antiproliferative activity

scientific article

Downregulation of TLX induces TET3 expression and inhibits glioblastoma stem cell self-renewal and tumorigenesis.

scientific article published on 3 February 2016

E2F signature is predictive for the pancreatic adenocarcinoma clinical outcome and sensitivity to E2F inhibitors, but not for the response to cytotoxic-based treatments.

scientific article

Efficient and innocuous delivery of small interfering RNA to microglia using an amphiphilic dendrimer nanovector

scientific article published on 28 August 2019

Efficient delivery of sticky siRNA and potent gene silencing in a prostate cancer model using a generation 5 triethanolamine-core PAMAM dendrimer

scientific article

Flavonoid-alkylphospholipid conjugates elicit dual inhibition of cancer cell growth and lipid accumulation

scientific article published on 04 July 2019

Genome-wide profiling identified a set of miRNAs that are differentially expressed in glioblastoma stem cells and normal neural stem cells.

scientific article

Heterocyst differentiation and pattern formation in cyanobacteria: a chorus of signals.

scientific article

High resolution magic angle spinning NMR to investigate ligand-receptor binding events for mass-limited samples in liquids

scientific article published on 15 October 2011

Impact of siRNA overhangs for dendrimer-mediated siRNA delivery and gene silencing.

scientific article published on 25 July 2013

Importance of size-to-charge ratio in construction of stable and uniform nanoscale RNA/dendrimer complexes.

scientific article published on 2 October 2007

Ligand-based design identifies a potent NUPR1 inhibitor exerting anticancer activity via necroptosis

scientific article published on 28 March 2019

Ligand-mediated highly effective and selective C-N coupling for synthesizing bioactive N-aryltriazole acyclonucleosides.

scientific article published on 18 November 2010

Liver Activation of Hepatocellular Nuclear Factor-4α by Small Activating RNA Rescues Dyslipidemia and Improves Metabolic Profile

scientific article published on 21 November 2019

Mastering Dendrimer Self-Assembly for Efficient siRNA Delivery: From Conceptual Design to In Vivo Efficient Gene Silencing

scientific article

Mimicking the 2-oxoglutaric acid signalling function using molecular probes: insights from structural and functional investigations

scientific article published on 01 July 2014

Mix and Match: Coassembly of Amphiphilic Dendrimers and Phospholipids Creates Robust, Modular, and Controllable Interfaces

scientific article

Mixed-ligand catalysts: a powerful tool in transition-metal- catalyzed cross-coupling reactions

scientific article published on 01 March 2014

Molecular and Genetic Analysis of Two Closely Linked Genes That Encode, Respectively, a Protein Phosphatase 1/2A/2B Homolog and a Protein Kinase Homolog in the Cyanobacterium Anabaena sp. Strain PCC 7120

scientific article published on May 1, 1998

Mutually induced formation of host-guest complexes between p-sulfonated calix[8]arene and photolabile cholinergic ligands

scientific article published on 01 December 2002

N-aryltriazole ribonucleosides with potent antiproliferative activity against drug-resistant pancreatic cancer.

scientific article published on 3 March 2010

Natural killer cells modulate motor neuron-immune cell cross talk in models of Amyotrophic Lateral Sclerosis

scientific article published on 14 April 2020

Negative dendritic effect on enzymatic hydrolysis of dendrimer conjugates

scientific article published on 01 June 2018

Novel RNA oligonucleotide improves liver function and inhibits liver carcinogenesis in vivo.

scientific article

Novel aryltriazole acyclic C-azanucleosides as anticancer candidates

scientific article published on 24 November 2020

Novel triazole nucleoside analogues promote anticancer activity via both apoptosis and autophagy

scientific article published on 29 July 2020

Novel triazole ribonucleoside down-regulates heat shock protein 27 and induces potent anticancer activity on drug-resistant pancreatic cancer.

scientific article published on October 2009

Nucleoside analog inhibits microRNA-214 through targeting heat-shock factor 1 in human epithelial ovarian cancer.

scientific article published on 22 October 2013

PAMAM dendrimers for efficient siRNA delivery and potent gene silencing

scientific article published on 10 May 2006

PAMAM dendrimers mediate siRNA delivery to target Hsp27 and produce potent antiproliferative effects on prostate cancer cells.

scientific article

Pd(dba)2 vs Pd2(dba)3: an in-depth comparison of catalytic reactivity and mechanism via mixed-ligand promoted C-N and C-S coupling reactions

scientific article published on 31 July 2014

Pd-catalyzed oxidative C-H alkenylation for synthesizing arylvinyltriazole nucleosides

scientific article published on 01 January 2015

Photoactivatable lipid probes for studying biomembranes by photoaffinity labeling.

scientific article published on 15 August 2013

Photoactivatable phospholipids bearing tetrafluorophenylazido chromophores exhibit unprecedented protonation-state-dependent 19F NMR signals

scientific article published on 18 July 2011

Photochemical labeling of membrane-associated and channel-forming domains of proteins directed by energy transfer.

scientific article

Polycationic dendrimers interact with RNA molecules: polyamine dendrimers inhibit the catalytic activity of Candida ribozymes.

scientific article published on 9 December 2004

Potent drugless dendrimers

scientific article published on 01 September 2017

Promoting siRNA delivery via enhanced cellular uptake using an arginine-decorated amphiphilic dendrimer

scientific article published on March 2015

Rationalizing the F⋯S interaction discovered within a tetrafluorophenylazido-containing bola-phospholipid

scientific article published on 08 February 2012

S-aryltriazole acyclonucleosides: synthesis and biological evaluation against hepatitis C virus

scientific article published on 28 April 2010

Self-Assembling Supramolecular Dendrimers for Biomedical Applications: Lessons Learned from Poly(amidoamine) Dendrimers

scientific article published on 04 December 2020

Self-assembling supramolecular dendrimer nanosystem for PET imaging of tumors

article published in the Proceedings of the National Academy of Sciences of the United States of America

Shape separation of gold nanoparticles using a pH-responsive amphiphilic dendrimer according to their shape anisotropy distinction.

scientific article published on 30 September 2014

Structural Requirements of 2-Oxoglutaric Acid Analogues To Mimic Its Signaling Function

scientific article published on 29 August 2013

Structural characterization of new defective molecules in poly(amidoamide) dendrimers by combining mass spectrometry and nuclear magnetic resonance

scientific article published on 31 October 2014

Structural characterization of poly(amino)ester dendrimers and related impurities by electrospray tandem mass spectrometry

scientific article published on 01 August 2010

Structurally flexible triethanolamine core PAMAM dendrimers are effective nanovectors for DNA transfection in vitro and in vivo to the mouse thymus.

scientific article published on 22 November 2011

Studying the signaling role of 2-oxoglutaric acid using analogs that mimic the ketone and ketal forms of 2-oxoglutaric acid

scientific article published on 01 August 2006

Surface Charge of Supramolecular Nanosystems for In Vivo Biodistribution: A MicroSPECT/CT Imaging Study

scientific article published on 14 August 2020

Synthesis and use of an amphiphilic dendrimer for siRNA delivery into primary immune cells

scientific article published on 04 December 2020

Synthesis of bitriazolyl nucleosides and unexpectedly different reactivity of azidotriazole nucleoside isomers in the Huisgen reaction

scientific article published on 25 April 2007

Synthesis of poly(amino)ester dendrimers via active cyanomethyl ester intermediates

scientific article published on 17 November 2010

Systemic Administration of Combinatorial dsiRNAs via Nanoparticles Efficiently Suppresses HIV-1 Infection in Humanized Mice

scientific article published on September 27, 2011

Targeted delivery of Dicer-substrate siRNAs using a dual targeting peptide decorated dendrimer delivery system.

scientific article

Targeting heat shock factor 1 with a triazole nucleoside analog to elicit potent anticancer activity on drug-resistant pancreatic cancer

scientific article published on January 20, 2012

Targeting heat shock response pathways to treat pancreatic cancer

scientific article published on October 1, 2011

Targeting the Stress-Induced Protein NUPR1 to Treat Pancreatic Adenocarcinoma

scientific article published on 17 November 2019

Thermostable ionizable lipid-like nanoparticle (iLAND) for RNAi treatment of hyperlipidemia

scientific article published on 16 February 2022