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List of works by Augusto Villanueva

A Hepatocellular Carcinoma 5-Gene Score Associated With Survival of Patients After Liver Resection

article

A conditional transposon-based insertional mutagenesis screen for genes associated with mouse hepatocellular carcinoma.

scientific article published on 22 February 2009

A genomic and clinical prognostic index for hepatitis C-related early-stage cirrhosis that predicts clinical deterioration

scientific article

A hepatic stellate cell gene expression signature associated with outcomes in hepatitis C cirrhosis and hepatocellular carcinoma after curative resection

scientific article published on 4 June 2015

A molecular signature to discriminate dysplastic nodules from early hepatocellular carcinoma in HCV cirrhosis.

scientific article

A phenotypical map of disseminated hepatocellular carcinoma suggests clonal constraints in metastatic sites

scientific article published on 21 February 2019

A pilot study of ultra-deep targeted sequencing of plasma DNA identifies driver mutations in hepatocellular carcinoma.

scientific article published on 9 April 2018

Accuracy of plasma levels of polymorphonuclear elastase as early prognostic marker of acute pancreatitis in routine clinical conditions

scientific article published on 01 January 2006

Advances in targeted therapies for hepatocellular carcinoma in the genomic era.

scientific article published on 09 June 2015

Biología celular y genética en el cáncer de hígado

scientific article published on 01 June 2007

Cancer gene discovery in hepatocellular carcinoma

scientific article

Carcinogen-induced hepatic tumors in KLF6+/- mice recapitulate aggressive human hepatocellular carcinoma associated with p53 pathway deregulation.

scientific article

Cell population genetics and deep sequencing: A novel approach for drivers discovery in hepatocellular carcinoma

article

Circulating tumor cells and cholangiocarcinoma

scientific article published on 11 September 2015

Clinical Trial Watch: Reports from the EASL International Liver Congress (ILC), Vienna, April 2015.

scientific article published on 18 June 2015

Combining clinical, pathology, and gene expression data to predict recurrence of hepatocellular carcinoma

scientific article

DNA methylation-based prognosis and epidrivers in hepatocellular carcinoma

scientific article published on 18 March 2015

DNA-PK-A candidate driver of hepatocarcinogenesis and tissue biomarker that predicts response to treatment and survival.

scientific article

Depicting the role of TP53 in hepatocellular carcinoma progression ⬇️

scientific article published on May 14, 2011

Divergent evolutionary trajectories in transplanted tumor models

scientific article published in October 2017

Effect of HCV clearance with direct-acting antiviral agents on HCC

scientific article published on 01 September 2016

Emerging signaling pathways in hepatocellular carcinoma.

scientific article published on September 2012

Enhanced hepatocarcinogenesis in mouse models and human hepatocellular carcinoma by coordinate KLF6 depletion and increased messenger RNA splicing ⬇️

scientific article published on August 27, 2012

Epigenetic priming in chronic liver disease impacts the transcriptional and genetic landscapes of hepatocellular carcinoma

scientific article published on 29 December 2021

Erratum: Advances in targeted therapies for hepatocellular carcinoma in the genomic era

scientific article published on 23 June 2015

Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targets

scientific article

Focal gains of VEGFA and molecular classification of hepatocellular carcinoma

scientific article published on August 2008

Gene expression in fixed tissues and outcome in hepatocellular carcinoma.

scientific article

Gene signatures in the management of hepatocellular carcinoma

scientific article published on August 1, 2012

Gene-expression signature of vascular invasion in hepatocellular carcinoma.

scientific article published on 13 April 2011

Genetic Landscape and Biomarkers of Hepatocellular Carcinoma.

scientific article published on 19 June 2015

Genetic profiling of hepatocellular carcinoma using next-generation sequencing.

scientific article published on June 2016

Genetically engineered mouse models: future tools to predict clinical trial results in oncology?

scientific article published in June 2013

Genomic tracing of the elusive liver cancer ancestor

scientific article published on 31 May 2010

Genomics and signaling pathways in hepatocellular carcinoma.

scientific article published on February 2007

Hepatocellular Carcinoma

scientific article published on 01 April 2019

Hepatocellular carcinoma enters the sequencing era.

scientific article published on 29 September 2011

High-density single cell mRNA sequencing to characterize circulating tumor cells in hepatocellular carcinoma

scientific article published on 01 August 2018

IGF activation in a molecular subclass of hepatocellular carcinoma and pre-clinical efficacy of IGF-1R blockage.

scientific article

IGF2 Is Up-regulated by Epigenetic Mechanisms in Hepatocellular Carcinomas and Is an Actionable Oncogene Product in Experimental Models

scientific article published on 7 September 2016

Identification of an Immune-specific Class of Hepatocellular Carcinoma, Based on Molecular Features

scientific article published on 14 June 2017

Impact of intra-individual molecular heterogeneity in personalized treatment of hepatocellular carcinoma

scientific article published on 01 December 2012

Intratumor molecular and phenotypic diversity in hepatocellular carcinoma

scientific article published on 27 January 2015

Intratumoral heterogeneity and clonal evolution in liver cancer

scientific article published on 15 January 2020

Linking molecular classification of hepatocellular carcinoma and personalized medicine: preliminary steps.

scientific article published on July 2008

Liquid biopsy in liver cancer

scientific article published on April 2015

Liver Cancer Cell of Origin, Molecular Class, and Effects on Patient Prognosis.

scientific article published on 30 December 2016

Liver cancer in 2013: Mutational landscape of HCC--the end of the beginning.

scientific article published on 07 January 2014

Liver capsule: Molecular-based signatures in hepatocellular carcinoma

scientific article published on 25 March 2016

Lymphotoxins: new targets for hepatocellular carcinoma

scientific article published on October 2009

Management of small hepatocellular carcinoma in cirrhosis: focus on portal hypertension

scientific article published on February 2013

Medical therapies for hepatocellular carcinoma: a critical view of the evidence ⬇️

scientific article published on November 13, 2012

Mixed hepatocellular cholangiocarcinoma tumors: Cholangiolocellular carcinoma is a distinct molecular entity

scientific article published on 23 January 2017

Molecular Liver Cancer Prevention in Cirrhosis by Organ Transcriptome Analysis and Lysophosphatidic Acid Pathway Inhibition

scientific article published on December 2016

Molecular epidemiology in HCV-related hepatocellular carcinoma: first steps.

scientific article published on 25 January 2012

Molecular pathogenesis of hepatocellular carcinoma.

scientific article published on 8 February 2011

Molecular predictors of prevention of recurrence in HCC with sorafenib as adjuvant treatment and prognostic factors in the phase 3 STORM trial

scientific article published on 14 August 2018

Molecular profiling to predict hepatocellular carcinoma outcome

scientific article published on April 2009

Molecular targeted therapies in hepatocellular carcinoma: From pre-clinical models to clinical trials

article

Mutations in circulating tumor DNA predict primary resistance to systemic therapies in advanced hepatocellular carcinoma

scientific article published on 23 October 2020

Natural history of nonalcoholic steatohepatitis/nonalcoholic fatty liver disease-hepatocellular carcinoma: Magnitude of the problem from a hepatology clinic perspective

scientific article published on 27 October 2016

Neoadjuvant therapies for hepatocellular carcinoma before liver transplantation: a critical appraisal.

scientific article published on December 2006

New strategies in hepatocellular carcinoma: genomic prognostic markers.

scientific article

Notch signaling is activated in human hepatocellular carcinoma and induces tumor formation in mice

scientific article

Pathogenesis of hepatocellular carcinoma and molecular therapies.

scientific article published on May 2009

Pivotal role of mTOR signaling in hepatocellular carcinoma

scientific article published on 20 August 2008

Preclinical overview of sorafenib, a multikinase inhibitor that targets both Raf and VEGF and PDGF receptor tyrosine kinase signaling

scientific article

Prognostic gene expression signature for patients with hepatitis C-related early-stage cirrhosis

scientific article published on 17 January 2013

Progress towards molecular patient stratification of hepatocellular carcinoma: Lost in translation?

scientific article

Randomized trials and endpoints in advanced HCC: Role of PFS as a surrogate of survival

scientific article published on 31 March 2019

Ras promotes growth by alternative splicing-mediated inactivation of the KLF6 tumor suppressor in hepatocellular carcinoma.

scientific article published on 13 February 2008

Rethinking future development of molecular therapies in hepatocellular carcinoma: a bottom-up approach.

scientific article published on 30 March 2013

Sex bias occurrence of hepatocellular carcinoma in Poly7 molecular subclass is associated with EGFR.

scientific article

Signaling pathways in hepatocellular carcinoma.

scientific article published on 22 December 2011

Systematic review: evidence-based management of hepatocellular carcinoma--an updated analysis of randomized controlled trials.

scientific article

Targeted therapies for hepatocellular carcinoma.

scientific article published on 13 March 2011

The Impact of Translational Research in Hepatology

scientific article published on 01 January 2019

The future of patient-derived tumor xenografts in cancer treatment

scientific article

The transition from inflammation to cancer in the liver

scientific article published on 27 October 2016

The usual SASPects of liver cancer

scientific article published on June 2015

Transplantation for hepatocellular carcinoma--worth waiting for?

scientific article published on 01 August 2014

Trunk mutational events present minimal intra- and inter-tumoral heterogeneity in hepatocellular carcinoma

scientific article published on 23 August 2017

Tumour evolution in hepatocellular carcinoma

scientific article published on 02 December 2019

Tumour initiating cells and IGF/FGF signalling contribute to sorafenib resistance in hepatocellular carcinoma

scientific article published on 11 December 2015

UHRF1 overexpression drives DNA hypomethylation and hepatocellular carcinoma

scientific article published on 30 January 2014

Unique genomic profile of fibrolamellar hepatocellular carcinoma

scientific article

Update in the therapeutic management of irritable bowel syndrome.

scientific article

VEGF Signaling in Cancer Treatment ⬇️

scientific article published on January 1, 2014

Why men are at higher risk for hepatocellular carcinoma?

scientific article

Wnt-pathway activation in two molecular classes of hepatocellular carcinoma and experimental modulation by sorafenib.

scientific article

[Genomic prognostic markers in hepatocellular carcinoma]

scientific article published on 16 December 2011

miRNA Delivery: Emerging Therapy for Hepatocellular Carcinoma

scientific article published on 25 January 2010

microRNAs: new ways to block tumor angiogenesis?

scientific article published on 09 June 2012

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