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List of works by Francoise Debart

1H and 31P-NMR assignments of the non-exchangeable protons of the consensus acceptor exon:intron junction d(CpTpApCpApGpGpT)

scientific article published on 01 June 1986

5-Propynylamino α-deoxyuridine promotes DNA duplex stabilization of anionic and neutral but not cationic α-oligonucleotides

scientific article published on 18 November 2006

A 2′,2′-disulfide-bridged dinucleotide conformationally locks RNA hairpins

scientific article published on 01 May 2018

A Whole Base-Labile Strategy for RNA Synthesis with 2'-O-acetalester Protections

scientific article published on 01 January 2008

A versatile post-synthetic method on a solid support for the synthesis of RNA containing reduction-responsive modifications.

scientific article published on 30 June 2016

Anomeric inversion (from beta to alpha) in methylphosphonate oligonucleosides enhances their affinity for DNA and RNA.

scientific article

Bacillus subtilis RNA deprotection enzyme RppH recognizes guanosine in the second position of its substrates

scientific article

Binding of the Methyl Donor S-Adenosyl-l-Methionine to Middle East Respiratory Syndrome Coronavirus 2'-O-Methyltransferase nsp16 Promotes Recruitment of the Allosteric Activator nsp10.

scientific article published on 28 December 2016

Cap-proximal nucleotides via differential eIF4E binding and alternative promoter usage mediate translational response to energy stress

scientific article published on 8 February 2017

Combining Chemical Synthesis and Enzymatic Methylation to Access Short RNAs with Various 5' Caps

scientific article published on 27 May 2019

Conjugation of Doxorubicin to siRNA Through Disulfide-based Self-immolative Linkers

scientific article published on 11 June 2020

Development of specific dengue virus 2'-O- and N7-methyltransferase assays for antiviral drug screening.

scientific article published on 12 June 2013

Direct synthesis of partially modified 2'-O-pivaloyloxymethyl RNAs by a base-labile protecting group strategy and their potential for prodrug-based gene-silencing applications

scientific article published on 24 October 2014

Efficient Solid-Phase Chemical Synthesis of 5′-Triphosphates of DNA, RNA, and their Analogues

scientific article published on 01 May 2010

Esterase-triggered fluorescence of fluorogenic oligonucleotides.

scientific article published in November 1997

FTIR and UV spectroscopy studies of triplex formation between alpha-oligonucleotides with non-ionic phoshoramidate linkages and DNA targets.

scientific article published in December 2003

FTIR and UV spectroscopy studies of triplex formation between pyrimidine methoxyethylphosphoramidates alpha-oligodeoxynucleotides and ds DNA targets.

scientific article published in June 2002

FTO controls reversible m6Am RNA methylation during snRNA biogenesis

scientific article published on 18 February 2019

FTO-mediated cytoplasmic m<sup>6</sup>A<sub>m</sub> demethylation adjusts stem-like properties in colorectal cancer cell

scientific article published on 19 March 2021

First Evaluation of Acyloxymethyl or Acylthiomethyl Groups as Biolabile 2‘-O-Protections of RNA†

scientific article published on 01 August 2006

Gymnotic delivery and gene silencing activity of reduction-responsive siRNAs bearing lipophilic disulfide-containing modifications at 2′-position

article

Highly stable DNA triplexes formed with cationic phosphoramidate pyrimidine alpha-oligonucleotides.

scientific article published in July 2005

Identification of the m6Am Methyltransferase PCIF1 Reveals the Location and Functions of m6Am in the Transcriptome

scientific article published on 03 July 2019

Imidazolethyl-phosphoramidate alpha-oligonucleotides.

scientific article published on May 2003

La-related protein 1 (LARP1) repression of TOP mRNA translation is mediated through its cap-binding domain and controlled by an adjacent regulatory region.

scientific article

Lipophilic 2'-O-Acetal Ester RNAs: Synthesis, Thermal Duplex Stability, Nuclease Resistance, Cellular Uptake, and siRNA Activity after Spontaneous Naked Delivery.

scientific article published on 29 August 2016

Molecular basis for nucleotide conservation at the ends of the dengue virus genome.

scientific article

Novel strategies towards construction of non-ionic and achiral backbones in antisense oligonucleotides ⬇️

scientific article published on January 1, 1992

Potent Inhibition of SARS-CoV-2 nsp14 <i>N</i>7-Methyltransferase by Sulfonamide-Based Bisubstrate Analogues

scientific article published on 19 April 2022

Step-by-step control by MALDI-TOF MS of an oligonucleotide synthesis on standard CPG solid-support.

scientific article

Stimuli-responsive oligonucleotides in prodrug-based approaches for gene silencing.

scientific article published on 19 February 2018

Structure and conformation of the duplex consensus 5'-splice site d[(CpApGpGpTpApApGpT).(ApCpTpTpApCpCpTpG)] deduced from high field 1H-NMR of the non-exchangeable and imino protons

scientific article published on 01 August 1987

Structure and conformation of the duplex consensus acceptor exon:intron junction d[(CpTpApCpApGpGpT). (ApCpCpTpGpTpApG)] deduced from high-field 1H-NMR of non-exchangeable and imino protons

scientific article published on 01 December 1986

Synthesis and Preliminary Evaluation of pro-RNA 2′-O-Masked with Biolabile Pivaloyloxymethyl Groups in an RNA Interference Assay

scientific article published on 16 June 2011

Synthesis of 5' cap-0 and cap-1 RNAs using solid-phase chemistry coupled with enzymatic methylation by human (guanine-N⁷)-methyl transferase.

scientific article published on 14 February 2012

Synthesis, DNA binding, and biological evaluation of synthetic precursors and novel analogues of netropsin

scientific article (publication date: May 1989)

Synthesis, binding, nuclease resistance and cellular uptake properties of 2'-O-acetalester-modified oligonucleotides containing cationic groups

scientific article published on 29 July 2015

The methyltransferase domain of the Respiratory Syncytial Virus L protein catalyzes cap N7 and 2'-O-methylation

scientific article published on 06 May 2021

The methyltransferase domain of the Sudan ebolavirus L protein specifically targets internal adenosines of RNA substrates, in addition to the cap structure

article

Toward high yield synthesis of peptide-oligonucleotide chimera through a disulfide bridge: a simplified method for oligonucleotide activation.

scientific article published in November 2005

Toward the identification of viral cap-methyltransferase inhibitors by fluorescence screening assay

scientific article published on July 2017

Use of MALDI-TOF mass spectrometry to monitor solid-phase synthesis of oligonucleotides

scientific article

X-ray structure and activities of an essential Mononegavirales L-protein domain

scientific article

[Ebola virus L protein harbors a new enzymatic activity involved in the internal methylation of RNAs].

scientific article published on 01 November 2018

mRNA maturation in giant viruses: variation on a theme.

scientific article

α-OLIGONUCLEOTIDES WITH ANIONIC PHOSPHODIESTER AND CATIONIC PHOSPHORAMIDATE LINKAGES ENHANCED STABILITY OF DNA TRIPLE HELIX

scientific article published on 01 April 2001

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