List of works - Brian J McHugh

Blood Neutrophils Are Reprogrammed in Bronchiectasis

Cathelicidin host defence peptide augments clearance of pulmonary Pseudomonas aeruginosa infection by its influence on neutrophil function in vivo

scientific article

Cathelicidin is a "fire alarm", generating protective NLRP3-dependent airway epithelial cell inflammatory responses during infection with Pseudomonas aeruginosa

article

Differential response to bacteria, and TOLLIP expression, in the human respiratory tract.

scientific article

Genetic basis of transferase-deficient galactosaemia in Ireland and the population history of the Irish Travellers.

scientific article

Human cathelicidin production by the cervix

scientific article

IL-1β-Induced Protection of Keratinocytes against Staphylococcus aureus-Secreted Proteases Is Mediated by Human β-Defensin 2.

scientific article published on 09 September 2016

Integrin activation by Fam38A uses a novel mechanism of R-Ras targeting to the endoplasmic reticulum

scientific article

Invadolysin: a novel, conserved metalloprotease links mitotic structural rearrangements with cell migration

scientific article

Loss of the integrin-activating transmembrane protein Fam38A (Piezo1) promotes a switch to a reduced integrin-dependent mode of cell migration

scientific article

Mammalian NOTCH-1 activates beta1 integrins via the small GTPase R-Ras.

scientific article

Mannose-binding lectin deficiency and disease severity in non-cystic fibrosis bronchiectasis: a prospective study

scientific article published on 28 January 2013

Microbial host interactions and impaired wound healing in mice and humans: defining a role for BD14 and NOD2.

scientific article

Phospholipase C epsilon suppresses integrin activation

scientific article published on 8 August 2006

Regulation of chromosome condensation and segregation

scientific article

Short- and long-term antibiotic treatment reduces airway and systemic inflammation in non-cystic fibrosis bronchiectasis

scientific article

The human cathelicidin LL-37 has antiviral activity against respiratory syncytial virus.

scientific article

Vitamin-D deficiency is associated with chronic bacterial colonisation and disease severity in bronchiectasis

scientific article published on 16 October 2012

List of works by Brian J McHugh

Blood Neutrophils Are Reprogrammed in Bronchiectasis

Cathelicidin host defence peptide augments clearance of pulmonary Pseudomonas aeruginosa infection by its influence on neutrophil function in vivo

Cathelicidin is a "fire alarm", generating protective NLRP3-dependent airway epithelial cell inflammatory responses during infection with Pseudomonas aeruginosa

Differential response to bacteria, and TOLLIP expression, in the human respiratory tract.

Genetic basis of transferase-deficient galactosaemia in Ireland and the population history of the Irish Travellers.

Human cathelicidin production by the cervix

IL-1β-Induced Protection of Keratinocytes against Staphylococcus aureus-Secreted Proteases Is Mediated by Human β-Defensin 2.

Integrin activation by Fam38A uses a novel mechanism of R-Ras targeting to the endoplasmic reticulum

Invadolysin: a novel, conserved metalloprotease links mitotic structural rearrangements with cell migration

Loss of the integrin-activating transmembrane protein Fam38A (Piezo1) promotes a switch to a reduced integrin-dependent mode of cell migration

Mammalian NOTCH-1 activates beta1 integrins via the small GTPase R-Ras.

Mannose-binding lectin deficiency and disease severity in non-cystic fibrosis bronchiectasis: a prospective study

Microbial host interactions and impaired wound healing in mice and humans: defining a role for BD14 and NOD2.

Phospholipase C epsilon suppresses integrin activation

Regulation of chromosome condensation and segregation

Short- and long-term antibiotic treatment reduces airway and systemic inflammation in non-cystic fibrosis bronchiectasis

The human cathelicidin LL-37 has antiviral activity against respiratory syncytial virus.

Vitamin-D deficiency is associated with chronic bacterial colonisation and disease severity in bronchiectasis