List of works - Tommi Nyrönen

A linear open-chain piperazine-pyridine ligand and its meso-helical Co complex

A structure-activity relationship study of catechol-O-methyltransferase inhibitors combining molecular docking and 3D QSAR methods

scientific article

An MO study of neutral C8 high-symmetry clusters

An in silico approach to discovering novel inhibitors of human sirtuin type 2.

scientific article published in December 2004

BODIL: a molecular modeling environment for structure-function analysis and drug design

scientific article published in June 2004

BRUTUS: optimization of a grid-based similarity function for rigid-body molecular superposition. 1. Alignment and virtual screening applications.

scientific article published in June 2005

Best practices in bioinformatics training for life scientists

scientific article published on 25 June 2013

Bioinformatics Training Network (BTN): a community resource for bioinformatics trainers.

scientific article

Bioinformatics training: a review of challenges, actions and support requirements.

scientific article published on 18 June 2010

Common ELIXIR Service for Researcher Authentication and Authorisation

Comparing the quality and predictiveness between 3D QSAR models obtained from manual and automated alignment

scientific article

Computational and functional analysis of the androgen receptor antagonist atraric acid and its derivatives

scientific article published on June 2013

Computationally identified novel diphenyl- and phenylpyridine androgen receptor antagonist structures

scientific article

Delivering ICT infrastructure for biomedical research

Determinants of antagonist binding at the alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor subunit, GluR-D. Role of the conserved arginine 507 and glutamate 727 residues

scientific article published in December 2002

Docking and three-dimensional quantitative structure-activity relationship (3D QSAR) analyses of nonsteroidal progesterone receptor ligands

scientific article published on 01 July 2006

Empirical validation of an automated approach to data use oversight

scientific article published on 10 November 2021

Future opportunities and trends for e-infrastructures and life sciences: going beyond the grid to enable life science data analysis

scientific article

Glucuronidation Converts Clopidogrel to a Strong Time-Dependent Inhibitor of CYP2C8: A Phase II Metabolite as a Perpetrator of Drug–Drug Interactions

scientific article published on 27 June 2014

Model structures of alpha-2 adrenoceptors in complex with automatically docked antagonist ligands raise the possibility of interactions dissimilar from agonist ligands

scientific article

Molecular evolution of adrenoceptors and dopamine receptors: implications for the binding of catecholamines

scientific article published in March 2006

Molecular mechanism for agonist-promoted alpha(2A)-adrenoceptor activation by norepinephrine and epinephrine.

scientific article published in May 2001

Molecular mechanisms of ligand-receptor interactions in transmembrane domain V of the alpha2A-adrenoceptor

scientific article

Orchestrating differential data access for translational research: a pilot implementation

scientific article

Registered access: authorizing data access

scientific article published on 2 August 2018

SOMA--workflow for small molecule property calculations on a multiplatform computing grid

scientific article published on March 2006

SOMA2 – open source framework for molecular modelling workflows

Small molecule designed to target metal binding site in the alpha2I domain inhibits integrin function.

scientific article published on 21 April 2007

Structural basis for computational screening of non-steroidal androgen receptor ligands

scientific article

The Data Use Ontology to streamline responsible access to human biomedical datasets

scientific article published on 10 November 2021

Three-dimensional Models of α2A-Adrenergic Receptor Complexes Provide a Structural Explanation for Ligand Binding

scientific article published in Journal of Biological Chemistry

Three-dimensional structure-activity relationships of nonsteroidal ligands in complex with androgen receptor ligand-binding domain.

scientific article published in February 2005

“RKKH” Peptides from the Snake Venom Metalloproteinase ofBothrops jararacaBind Near the Metal Ion-dependent Adhesion Site of the Human Integrin α2I-domain

scientific article published in Journal of Biological Chemistry

List of works by Tommi Nyrönen

A linear open-chain piperazine-pyridine ligand and its meso-helical Co complex

A structure-activity relationship study of catechol-O-methyltransferase inhibitors combining molecular docking and 3D QSAR methods

An MO study of neutral C8 high-symmetry clusters

An in silico approach to discovering novel inhibitors of human sirtuin type 2.

BODIL: a molecular modeling environment for structure-function analysis and drug design

BRUTUS: optimization of a grid-based similarity function for rigid-body molecular superposition. 1. Alignment and virtual screening applications.

Best practices in bioinformatics training for life scientists

Bioinformatics Training Network (BTN): a community resource for bioinformatics trainers.

Bioinformatics training: a review of challenges, actions and support requirements.

Common ELIXIR Service for Researcher Authentication and Authorisation

Comparing the quality and predictiveness between 3D QSAR models obtained from manual and automated alignment

Computational and functional analysis of the androgen receptor antagonist atraric acid and its derivatives

Computationally identified novel diphenyl- and phenylpyridine androgen receptor antagonist structures

Delivering ICT infrastructure for biomedical research

Determinants of antagonist binding at the alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor subunit, GluR-D. Role of the conserved arginine 507 and glutamate 727 residues

Docking and three-dimensional quantitative structure-activity relationship (3D QSAR) analyses of nonsteroidal progesterone receptor ligands

Empirical validation of an automated approach to data use oversight

Future opportunities and trends for e-infrastructures and life sciences: going beyond the grid to enable life science data analysis

Glucuronidation Converts Clopidogrel to a Strong Time-Dependent Inhibitor of CYP2C8: A Phase II Metabolite as a Perpetrator of Drug–Drug Interactions

Model structures of alpha-2 adrenoceptors in complex with automatically docked antagonist ligands raise the possibility of interactions dissimilar from agonist ligands

Molecular evolution of adrenoceptors and dopamine receptors: implications for the binding of catecholamines

Molecular mechanism for agonist-promoted alpha(2A)-adrenoceptor activation by norepinephrine and epinephrine.

Molecular mechanisms of ligand-receptor interactions in transmembrane domain V of the alpha2A-adrenoceptor

Orchestrating differential data access for translational research: a pilot implementation

Registered access: authorizing data access

SOMA--workflow for small molecule property calculations on a multiplatform computing grid

SOMA2 – open source framework for molecular modelling workflows

Small molecule designed to target metal binding site in the alpha2I domain inhibits integrin function.

Structural basis for computational screening of non-steroidal androgen receptor ligands

The Data Use Ontology to streamline responsible access to human biomedical datasets

Three-dimensional Models of α2A-Adrenergic Receptor Complexes Provide a Structural Explanation for Ligand Binding

Three-dimensional structure-activity relationships of nonsteroidal ligands in complex with androgen receptor ligand-binding domain.

“RKKH” Peptides from the Snake Venom Metalloproteinase ofBothrops jararacaBind Near the Metal Ion-dependent Adhesion Site of the Human Integrin α2I-domain