List of works - Sahil Adriouch

A new genotoxicity assay based on p53 target gene induction

scientific article published on 29 May 2015

ADP-ribosylation of P2X7: a matter of life and death for regulatory T cells and natural killer T cells.

scientific article

ADP-ribosylation of membrane proteins: unveiling the secrets of a crucial regulatory mechanism in mammalian cells.

scientific article

AMPK Activation of PGC-1α/NRF-1-Dependent SELENOT Gene Transcription Promotes PACAP-Induced Neuroendocrine Cell Differentiation Through Tolerance to Oxidative Stress

article

Alternative splicing of the N-terminal cytosolic and transmembrane domains of P2X7 controls gating of the ion channel by ADP-ribosylation.

scientific article

CRISPR-Barcoding for Intratumor Genetic Heterogeneity Modeling and Functional Analysis of Oncogenic Driver Mutations.

scientific article published on 19 July 2016

Characterisation of the R276A gain-of-function mutation in the ectodomain of murine P2X7

scientific article published on 21 February 2009

Chromosomal instability but lack of transformation in human myoblast preparations.

scientific article published on January 2014

Clonal Proliferation and Stochastic Pruning Orchestrate Lymph Node Vasculature Remodeling.

scientific article published in October 2016

Contribution of genotoxic anticancer treatments to the development of multiple primary tumours in the context of germline TP53 mutations

article

Convergent alteration of granulopoiesis, chemotactic activity, and neutrophil apoptosis during mouse selection for high acute inflammatory response

scientific article

Corrigendum to “Evaluation and comparison of three different separation techniques for analysis of retroamide enantiomers and their biological evaluation against h -P2X7 receptor” [J. Chromatogr. B 986–987 (2015) 35–43]

scientific article published on 24 May 2016

Cutting edge: CD4-independent development of functional FoxP3+ regulatory T cells.

scientific article published in October 2009

Ecto-ADP-ribosyltransferase ARTC2.1 functionally modulates FcγR1 and FcγR2B on murine microglia

scientific article published on 28 November 2017

Evaluation and comparison of three different separation techniques for analysis of retroamide enantiomers and their biological evaluation against h-P2X7 receptor

scientific article published on 09 February 2015

Extracellular NAD and ATP: Partners in immune cell modulation.

scientific article

Extracellular NAD(+): a danger signal hindering regulatory T cells.

scientific article published on 24 May 2012

Generation of Pure Highly Functional Human Anti-Tumor Specific Cytotoxic T Lymphocytes With Stem Cell-Like Memory Features for Melanoma Immunotherapy

scientific article published on 08 September 2021

Genetic and Pharmacological Inactivation of the Purinergic P2RX7 Receptor Dampens Inflammation but Increases Tumor Incidence in a Mouse Model of Colitis-Associated Cancer

article

HACE1 is a putative tumor suppressor gene in B-cell lymphomagenesis and is down-regulated by both deletion and epigenetic alterations

scientific article published on 11 April 2016

Immunological tolerance to muscle autoantigens involves peripheral deletion of autoreactive CD8+ T cells

scientific article

Improved Immunological Tolerance Following Combination Therapy with CTLA-4/Ig and AAV-Mediated PD-L1/2 Muscle Gene Transfer.

scientific article

Intrinsic transgene immunogenicity gears CD8(+) T-cell priming after rAAV-mediated muscle gene transfer.

scientific article

Mechanical-stretch of C2C12 myoblasts inhibits expression of Toll-like receptor 3 (TLR3) and of autoantigens associated with inflammatory myopathies

scientific article

Monitoring Expression and Enzyme Activity of Ecto-ARTCs

scientific article published on 01 January 2018

Myoinjury transiently activates muscle antigen-specific CD8+ T cells in lymph nodes in a mouse model

article

Nanobody-Enhanced Targeting of AAV Gene Therapy Vectors

scientific article published on 16 September 2019

Novel biologics targeting the P2X7 ion channel

scientific article published on 12 April 2019

Oral-tolerization Prevents Immune Responses and Improves Transgene Persistence Following Gene Transfer Mediated by Adeno-associated Viral Vector

scientific article published on 12 August 2015

Overexpression of MHC class I in muscle of lymphocyte-deficient mice causes a severe myopathy with induction of the unfolded protein response.

scientific article published on 12 July 2013

P2X7 on Mouse T Cells: One Channel, Many Functions

scientific article published on 19 May 2015

P2X7 receptor induces mitochondrial failure in monocytes and compromises NLRP3 inflammasome activation during sepsis.

scientific article

Probing the expression and function of the P2X7 purinoceptor with antibodies raised by genetic immunization.

scientific article published on July 2005

Prophylactic Injection of Recombinant Alpha-Enolase Reduces Arthritis Severity in the Collagen-Induced Arthritis Mice Model

scientific article published on 24 August 2015

Pyroglutamide-Based P2X7 Receptor Antagonists Targeting Inflammatory Bowel Disease

scientific article published on 27 September 2019

Receptor Activator of NF-κB Orchestrates Activation of Antiviral Memory CD8 T Cells in the Spleen Marginal Zone.

scientific article published in November 2017

Role of M2-like macrophage recruitment during angiogenic growth factor therapy

scientific article published on 24 December 2014

Role of Toll-like receptors 2 and 4 in mediating endothelial dysfunction and arterial remodeling in primary arterial antiphospholipid syndrome

scientific article published in November 2014

Single domain antibodies: promising experimental and therapeutic tools in infection and immunity

scientific article

Suppression of asthma-like responses in different mouse strains by oral tolerance.

scientific article

Tuning IL-2 signaling by ADP-ribosylation of CD25.

scientific article published on 10 March 2015

Vector uncoating limits adeno-associated viral vector-mediated transduction of human dendritic cells and vector immunogenicity

scientific article published on 06 March 2019

List of works by Sahil Adriouch

A new genotoxicity assay based on p53 target gene induction

ADP-ribosylation of P2X7: a matter of life and death for regulatory T cells and natural killer T cells.

ADP-ribosylation of membrane proteins: unveiling the secrets of a crucial regulatory mechanism in mammalian cells.

AMPK Activation of PGC-1α/NRF-1-Dependent SELENOT Gene Transcription Promotes PACAP-Induced Neuroendocrine Cell Differentiation Through Tolerance to Oxidative Stress

Alternative splicing of the N-terminal cytosolic and transmembrane domains of P2X7 controls gating of the ion channel by ADP-ribosylation.

CRISPR-Barcoding for Intratumor Genetic Heterogeneity Modeling and Functional Analysis of Oncogenic Driver Mutations.

Characterisation of the R276A gain-of-function mutation in the ectodomain of murine P2X7

Chromosomal instability but lack of transformation in human myoblast preparations.

Clonal Proliferation and Stochastic Pruning Orchestrate Lymph Node Vasculature Remodeling.

Contribution of genotoxic anticancer treatments to the development of multiple primary tumours in the context of germline TP53 mutations

Convergent alteration of granulopoiesis, chemotactic activity, and neutrophil apoptosis during mouse selection for high acute inflammatory response

Corrigendum to “Evaluation and comparison of three different separation techniques for analysis of retroamide enantiomers and their biological evaluation against h -P2X7 receptor” [J. Chromatogr. B 986–987 (2015) 35–43]

Cutting edge: CD4-independent development of functional FoxP3+ regulatory T cells.

Ecto-ADP-ribosyltransferase ARTC2.1 functionally modulates FcγR1 and FcγR2B on murine microglia

Evaluation and comparison of three different separation techniques for analysis of retroamide enantiomers and their biological evaluation against h-P2X7 receptor

Extracellular NAD and ATP: Partners in immune cell modulation.

Extracellular NAD(+): a danger signal hindering regulatory T cells.

Generation of Pure Highly Functional Human Anti-Tumor Specific Cytotoxic T Lymphocytes With Stem Cell-Like Memory Features for Melanoma Immunotherapy

Genetic and Pharmacological Inactivation of the Purinergic P2RX7 Receptor Dampens Inflammation but Increases Tumor Incidence in a Mouse Model of Colitis-Associated Cancer

HACE1 is a putative tumor suppressor gene in B-cell lymphomagenesis and is down-regulated by both deletion and epigenetic alterations

Immunological tolerance to muscle autoantigens involves peripheral deletion of autoreactive CD8+ T cells

Improved Immunological Tolerance Following Combination Therapy with CTLA-4/Ig and AAV-Mediated PD-L1/2 Muscle Gene Transfer.

Intrinsic transgene immunogenicity gears CD8(+) T-cell priming after rAAV-mediated muscle gene transfer.

Mechanical-stretch of C2C12 myoblasts inhibits expression of Toll-like receptor 3 (TLR3) and of autoantigens associated with inflammatory myopathies

Monitoring Expression and Enzyme Activity of Ecto-ARTCs

Myoinjury transiently activates muscle antigen-specific CD8+ T cells in lymph nodes in a mouse model

Nanobody-Enhanced Targeting of AAV Gene Therapy Vectors

Novel biologics targeting the P2X7 ion channel

Oral-tolerization Prevents Immune Responses and Improves Transgene Persistence Following Gene Transfer Mediated by Adeno-associated Viral Vector

Overexpression of MHC class I in muscle of lymphocyte-deficient mice causes a severe myopathy with induction of the unfolded protein response.

P2X7 on Mouse T Cells: One Channel, Many Functions

P2X7 receptor induces mitochondrial failure in monocytes and compromises NLRP3 inflammasome activation during sepsis.

Probing the expression and function of the P2X7 purinoceptor with antibodies raised by genetic immunization.

Prophylactic Injection of Recombinant Alpha-Enolase Reduces Arthritis Severity in the Collagen-Induced Arthritis Mice Model

Pyroglutamide-Based P2X7 Receptor Antagonists Targeting Inflammatory Bowel Disease

Receptor Activator of NF-κB Orchestrates Activation of Antiviral Memory CD8 T Cells in the Spleen Marginal Zone.

Role of M2-like macrophage recruitment during angiogenic growth factor therapy

Role of Toll-like receptors 2 and 4 in mediating endothelial dysfunction and arterial remodeling in primary arterial antiphospholipid syndrome

Single domain antibodies: promising experimental and therapeutic tools in infection and immunity

Suppression of asthma-like responses in different mouse strains by oral tolerance.

Tuning IL-2 signaling by ADP-ribosylation of CD25.

Vector uncoating limits adeno-associated viral vector-mediated transduction of human dendritic cells and vector immunogenicity