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List of works by Peter Valent

"Occult" mastocytosis with activating c-kit point mutation evolving into systemic mastocytosis associated with plasma cell myeloma and secondary amyloidosis.

scientific article published on August 2006

10th anniversary of the Austrian MDS Platform: aims and ongoing projects.

scientific article published on 25 November 2014

123I-vasoactive intestinal peptide (VIP) receptor scanning: Update of imaging results in patients with adenocarcinomas and endocrine tumors of the gastrointestinal tract

scientific article published on 01 August 1996

1995 Mack-Forster Award Lecture. Review. Mast cell differentiation antigens: expression in normal and malignant cells and use for diagnostic purposes.

scientific article

A case of bone marrow mastocytosis associated with multiple myeloma

scientific article published on 01 March 1998

A case of smouldering mastocytosis with peripheral blood eosinophilia and lymphadenopathy

scientific article published on 01 June 2002

A human monoclonal IgE antibody defines a highly allergenic fragment of the major timothy grass pollen allergen, Phl p 5: molecular, immunological, and structural characterization of the epitope-containing domain.

scientific article

A hybrid molecule resembling the epitope spectrum of grass pollen for allergy vaccination.

scientific article published in May 2005

A hypoallergenic cat vaccine based on Fel d 1-derived peptides fused to hepatitis B PreS.

scientific article

A hypoallergenic hybrid molecule with increased immunogenicity consisting of derivatives of the major grass pollen allergens, Phl p 2 and Phl p 6

scientific article published on 01 July 2008

A hypoallergenic peptide mix containing T cell epitopes of the clinically relevant house dust mite allergens

scientific article published on 03 October 2019

A kinase profile-adapted drug combination elicits synergistic cooperative effects on leukemic cells carrying BCR-ABL1T315I in Ph+ CML

scientific article published on 28 December 2018

A molecular model of type I allergy: identification and characterization of a nonanaphylactic anti-human IgE antibody fragment that blocks the IgE-FcepsilonRI interaction and reacts with receptor-bound IgE.

scientific article published in September 2001

A new human mast cell line expressing a functional IgE receptor converts to tumorigenic growth by KIT D816V transfection

scientific article published on 27 March 2014

A novel effective and safe consolidation for patients over 60 years with acute myeloid leukemia: intermediate dose cytarabine (2 x 1 g/m2 on days 1, 3, and 5).

scientific article published on June 2004

A phase I study of lenalidomide in patients with chronic myelomonocytic leukemia (CMML) - AGMT_CMML-1.

scientific article published on 30 August 2017

A randomized, open-label, phase I/II trial to investigate the maximum tolerated dose of the Polo-like kinase inhibitor BI 2536 in elderly patients with refractory/relapsed acute myeloid leukaemia

scientific article published on 16 August 2013

A recombinant hypoallergenic parvalbumin mutant for immunotherapy of IgE-mediated fish allergy.

scientific article published in May 2007

Aberrant expression of CD30 in aggressive systemic mastocytosis and mast cell leukemia: a differential diagnosis to consider in aggressive hematopoietic CD30-positive neoplasms.

scientific article published on 24 January 2011

Acute myeloid leukaemia with t(8;21) associated with "occult" mastocytosis. Report of an unusual case and review of the literature.

scientific article published on March 2004

Additional prognostic impact of the percentage of erythroid cells in the bone marrow of patients with myelodysplastic syndromes

scientific article published on 28 December 2018

Advanced systemic mastocytosis: from molecular and genetic progress to clinical practice

scientific article

Advances in the Classification and Treatment of Mastocytosis: Current Status and Outlook toward the Future.

scientific article

Aggressive B-cell lymphomas in patients with myelofibrosis receiving JAK1/2 inhibitor therapy

scientific article published on 14 June 2018

Aggressive systemic mastocytosis with sarcoma-like growth in the skeleton, leukemic progression, and partial loss of mast cell differentiation antigens

scientific article published on 01 December 2007

Aleukemic mast cell leukemia with abnormal immunophenotype and c-kit mutation D816V

scientific article published on 01 November 2004

All systems red.

scientific article published on 25 October 2014

Allergen cleavage by effector cell-derived proteases regulates allergic inflammation.

scientific article published on 3 April 2006

Allergen-specific immunotherapy with a monophosphoryl lipid A-adjuvanted vaccine: reduced seasonally boosted immunoglobulin E production and inhibition of basophil histamine release by therapy-induced blocking antibodies.

scientific article published in September 2003

Allogeneic hematopoietic cell transplantation in systemic mastocytosis: is there a high risk for veno-occlusive disease?

scientific article published on 17 December 2015

Altered IgE epitope presentation: A model for hypoallergenic activity revealed for Bet v 1 trimer.

scientific article published on 18 November 2010

Amplification of ribosomal RNA genes in acute myeloid leukemia

scientific article published on 01 September 2001

Amplification of the AML1(CBFA2) gene on ring chromosomes in a patient with acute myeloid leukemia and a constitutional ring chromosome 21

scientific article published on 01 January 2001

Amplification of the MLL gene on double minutes, a homogeneously staining region, and ring chromosomes in five patients with acute myeloid leukemia or myelodysplastic syndrome

scientific article published on 01 April 2000

An in vitro model for the allergen-IgE-FcARI interaction

scientific article published on 01 February 1999

An increased bone mineral density is an adverse prognostic factor in patients with systemic mastocytosis

scientific article published on 24 January 2020

Anaemia of the elderly (AOE): does it exist and does it matter in clinical practice?

scientific article published on 01 October 2008

Anemia at older age: etiologies, clinical implications and management

scientific article published on 15 November 2017

Angiosarcoma of bone marrow with unusual expression of chymase: diagnosis in a trephine biopsy specimen

scientific article published on October 2007

Antibody conjugates bispecific for intercellular adhesion molecule 1 and allergen prevent migration of allergens through respiratory epithelial cell layers

scientific article published on 11 March 2015

Autoantibody reactivity in a case of Schnitzler's syndrome: evidence for a Th1-like response and detection of IgG2 anti-FcepsilonRIalpha antibodies

scientific article published on 01 August 2000

Autocrine fibroblast growth factor 18 signaling mediates Wnt-dependent stimulation of CD44-positive human colorectal adenoma cells.

scientific article published on 12 March 2014

Autoimmune thrombocytopenia in non-Hodgkin's lymphomas.

scientific article

B cell epitopes of the major timothy grass pollen allergen, phl p 1, revealed by gene fragmentation as candidates for immunotherapy

scientific article published on 01 August 1999

BCR-ABL1 compound mutants display differential and dose-dependent responses to ponatinib

scientific article

BCR/ABL induces expression of vascular endothelial growth factor and its transcriptional activator, hypoxia inducible factor-1alpha, through a pathway involving phosphoinositide 3-kinase and the mammalian target of rapamycin.

scientific article published on 18 July 2002

BET-Bromodomain Inhibitors Engage the Host Immune System and Regulate Expression of the Immune Checkpoint Ligand PD-L1

scientific article

BRD4: a BET(ter) target for the treatment of AML?

scientific article published on 21 January 2014

BTK inhibition is a potent approach to block IgE-mediated histamine release in human basophils

scientific article

Basophils are not the key antigen-presenting cells in allergic patients

scientific article published on 16 February 2012

Biology and clinical features of myeloid neoplasms with inv(3)(q21q26) or t(3;3)(q21q26).

scientific article published in November 2007

Bone marrow microvessel density and its prognostic significance in AML

scientific article published on 01 July 2004

C5a stimulates production of plasminogen activator inhibitor-1 in human mast cells and basophils.

scientific article published on July 2002

CCI-779 plus cisplatin is highly effective against human melanoma in a SCID mouse xenotranplantation model.

scientific article published on 22 March 2007

CCL2 is a KIT D816V-dependent modulator of the bone marrow microenvironment in systemic mastocytosis.

scientific article published on 16 November 2016

CD44 is a RAS/STAT5-regulated invasion receptor that triggers disease expansion in advanced mastocytosis

scientific article published on 17 July 2018

CD44-positive colorectal adenoma cells express the potential stem cell markers musashi antigen (msi1) and ephrin B2 receptor (EphB2).

scientific article published on October 2007

CD52 is a molecular target in advanced systemic mastocytosis.

scientific article published on 23 April 2014

CDK6 coordinates JAK2 V617F mutant MPN via NF-κB and apoptotic networks

scientific article published on 11 January 2019

CDK6 is an essential direct target of NUP98-fusion proteins in acute myeloid leukemia

scientific article published on 28 April 2020

CEBPA-mutated leukemia is sensitive to genetic and pharmacological targeting of the MLL1 complex

scientific article published on 24 January 2019

Cancer stem cells in basic science and in translational oncology: can we translate into clinical application?

scientific article

Carrier-bound Alt a 1 peptides without allergenic activity for vaccination against Alternaria alternata allergy.

scientific article published on June 2012

Carrier-bound nonallergenic Der p 2 peptides induce IgG antibodies blocking allergen-induced basophil activation in allergic patients.

scientific article

Cell surface membrane antigen phenotype of human gastrointestinal mast cells

scientific article published on 20 September 2005

Cell surface structures on human basophils and mast cells: biochemical and functional characterization

scientific article published on January 1, 1992

Characterization of Der p 21, a new important allergen derived from the gut of house dust mites.

scientific article

Characterization of folded recombinant Der p 5, a potential diagnostic marker allergen for house dust mite allergy

scientific article

Characterization of human prostate mast cells and their increase in periprostatic vein thrombosis

scientific article published on 01 July 2001

Characterization of prostaglandin (PG)-binding sites expressed on human basophils. Evidence for a prostaglandin E1, I2, and a D2 receptor ⬇️

scientific article published on June 25, 1992

Characterization of recombinant cat albumin

scientific article published on 01 December 2003

Characterization of wild-type recombinant Bet v 1a as a candidate vaccine against birch pollen allergy.

scientific article

Characterization of123I-vascular endothelial growth factor-binding sites expressed on human tumour cells: Possible implication for tumour scintigraphy

scientific article published on 01 March 2001

Chemical proteomic profiles of the BCR-ABL inhibitors imatinib, nilotinib, and dasatinib reveal novel kinase and nonkinase targets

scientific article published on 24 August 2007

Chronic mast cell leukemia (MCL) with KIT S476I: a rare entity defined by leukemic expansion of mature mast cells and absence of organ damage

scientific article published on 11 September 2014

Chronic mast cell leukemia: a novel leukemia-variant with distinct morphological and clinical features

scientific article

Chronic myelomonocytic leukemia patients with RAS pathway mutations show high in vitro myeloid colony formation in the absence of exogenous growth factors.

scientific article published on 2 September 2016

Cigarette smoke facilitates allergen penetration across respiratory epithelium.

scientific article

Circulating myeloid colony-forming cells predict survival in myelodysplastic syndromes.

scientific article published on 22 March 2003

Classification and response criteria in mast cell disorders: time to revise?

scientific article published on 03 February 2011

Classification and response criteria in mastocytosis: is there a need to revise?

scientific article published on 01 June 2010

Clinical Impact of Inherited and Acquired Genetic Variants in Mastocytosis

scientific article published on 02 January 2021

Clinical Impact of Skin Lesions in Mastocytosis: A Multicenter Study of the European Competence Network on Mastocytosis

scientific article published in July 2021

Clinical Outcomes of 217 Patients with Acute Erythroleukemia According to Treatment Type and Line: A Retrospective Multinational Study.

scientific article published on 14 April 2017

Clinical and biologic diversity of leukemias occurring in patients with mastocytosis.

scientific article published in May 2000

Clinical and laboratory parameters of mast cell activation as basis for the formulation of diagnostic criteria.

scientific article published on 16 May 2011

Clinical and prognostic significance of histamine monitoring in patients with CML during treatment with imatinib (STI571)

scientific article published on 05 September 2007

Clinical perspectives of concepts on neoplastic stem cells and stem cell-resistance in chronic myeloid leukemia.

scientific article published on April 2008

Clinical, Hematologic, Biologic and Molecular Characteristics of Patients with Myeloproliferative Neoplasms and a Chronic Myelomonocytic Leukemia-Like Phenotype

scientific article published on 14 July 2020

Clofarabine/cyclophosphamide for debulking before stem cell transplantation

scientific article published on 01 August 2014

Clonal Hematopoiesis of Indeterminate Potential: A Multidisciplinary Challenge in Personalized Hematology

scientific article published on 20 August 2020

Clonal Hematopoiesis with Oncogenic Potential (CHOP): Separation from CHIP and Roads to AML

scientific article published on 12 February 2019

Clonal architecture in patients with myelodysplastic syndromes and double or minor complex abnormalities: Detailed analysis of clonal composition, involved abnormalities, and prognostic significance

scientific article published on 24 September 2018

Clustering of comorbidities is related to age and sex and impacts clinical outcome in myelodysplastic syndromes.

scientific article published on 11 March 2014

Co-operating STAT5 and AKT signaling pathways in chronic myeloid leukemia and mastocytosis: possible new targets of therapy

scientific article published on March 2014

Coalesced Multicentric Analysis of 2,351 Patients With Myelodysplastic Syndromes Indicates an Underestimation of Poor-Risk Cytogenetics of Myelodysplastic Syndromes in the International Prognostic Scoring System ⬇️

scientific article published on April 25, 2011

Cold antibody autoimmune hemolytic anemia and lymphoproliferative disorders: a retrospective study of 20 patients including clinical, hematological, and molecular findings

scientific article published on 20 May 2014

Combination treatment of acute myeloblastic leukemia with rhGM-CSF and standard induction chemotherapy

scientific article published on 01 January 1993

Comorbidity predicts survival in myelodysplastic syndromes or secondary acute myeloid leukaemia after allogeneic stem cell transplantation.

scientific article published in December 2008

Comorbidity, iron overload and HFE variants: a new prognostic complex in MDS?

scientific article published on 10 July 2009

Comparative analysis of IL6 and IL6 receptor gene polymorphisms in mastocytosis

scientific article

Comparative immunophenotypic analysis of human mast cells, blood basophils and monocytes

scientific article published on 01 April 1996

Comparative oncology: The paradigmatic example of canine and human mast cell neoplasms

scientific article published on 24 September 2018

Consensus Opinion on Allogeneic Hematopoietic Cell Transplantation in Advanced Systemic Mastocytosis.

scientific article published on 27 April 2016

Constitutive activation of Stat5 promotes its cytoplasmic localization and association with PI3-kinase in myeloid leukemias

scientific article published on 12 October 2006

Conversion of Der p 23, a new major house dust mite allergen, into a hypoallergenic vaccine.

scientific article

Conversion of the major birch pollen allergen, Bet v 1, into two nonanaphylactic T cell epitope-containing fragments: candidates for a novel form of specific immunotherapy

scientific article published on April 1997

Correlation of RAS-Pathway Mutations and Spontaneous Myeloid Colony Growth with Progression and Transformation in Chronic Myelomonocytic Leukemia-A Retrospective Analysis in 337 Patients

scientific article published on 24 April 2020

Current treatment options in patients with mastocytosis: status in 2015 and future perspectives

scientific article

Cutaneous manifestations in patients with mastocytosis: Consensus report of the European Competence Network on Mastocytosis; the American Academy of Allergy, Asthma & Immunology; and the European Academy of Allergology and Clinical Immunology

scientific article published on 15 October 2015

Cytokine Regulation of Microenvironmental Cells in Myeloproliferative Neoplasms

scientific article

Dasatinib inhibits the growth and survival of neoplastic human eosinophils (EOL-1) through targeting of FIP1L1-PDGFRalpha.

scientific article

Dasatinib-induced immunosuppression and recurrent respiratory tract infections

scientific article published on 11 December 2014

Deferasirox induces regression of iron overload in patients with myelodysplastic syndromes.

scientific article

Der p 11 is a major allergen for house dust mite-allergic patients suffering from atopic dermatitis.

scientific article

Detection of c-kit mutation Asp 816 to Val in microdissected bone marrow infiltrates in a case of systemic mastocytosis associated with chronic myelomonocytic leukaemia.

scientific article published on August 2000

Detection of c-kit point mutation Asp-816 --> Val in microdissected pooled single mast cells and leukemic cells in a patient with systemic mastocytosis and concomitant chronic myelomonocytic leukemia.

scientific article

Detection of molecular targets on the surface of CD34+/CD38-- stem cells in various myeloid malignancies.

scientific article

Detection of novel leukocyte differentiation antigens on basophils and mast cells by HLDA8 antibodies.

scientific article published on September 2006

Detection of vascular endothelial growth factor (VEGF) and VEGF receptors Flt-1 and KDR in canine mastocytoma cells.

scientific article published on 17 November 2006

Development and characterization of a recombinant, hypoallergenic, peptide-based vaccine for grass pollen allergy.

scientific article published on 13 November 2014

Diagnosis and classification of mast cell proliferative disorders: delineation from immunologic diseases and non-mast cell hematopoietic neoplasms.

scientific article published in July 2004

Diagnosis and management of mastocytosis: an emerging challenge in applied hematology

scientific article

Diagnosis of mastocytosis: general histopathological aspects, morphological criteria, and immunohistochemical findings.

scientific article published in July 2001

Diagnosis, Classification and Management of Mast Cell Activation Syndromes (MCAS) in the Era of Personalized Medicine

scientific article published on 27 November 2020

Diagnosis, management and response criteria of iron overload in myelodysplastic syndromes (MDS): updated recommendations of the Austrian MDS platform

scientific article published on 02 January 2018

Diagnostic and prognostic value of new biochemical and immunohistochemical parameters in chronic myeloid leukemia.

scientific article published on April 2008

Diagnostic and subdiagnostic accumulation of mast cells in the bone marrow of patients with anaphylaxis: Monoclonal mast cell activation syndrome.

scientific article published on 20 October 2006

Diagnostic criteria and classification of mastocytosis in 2014.

scientific article published on May 2014

Diagnostic value of histology and immunohistochemistry in myelodysplastic syndromes.

scientific article published on 2 July 2007

Diagnostic value of immunostaining for tryptase in patients with mastocytosis

scientific article published on 01 September 1998

Differential response of human basophils and mast cells to recombinant chemokines

scientific article published on 01 May 1995

Differing clinical features between Japanese and Caucasian patients with myelodysplastic syndromes: Analysis from the International Working Group for Prognosis of MDS

scientific article published on 06 September 2018

Digital PCR: A Sensitive and Precise Method for KIT D816V Quantification in Mastocytosis

scientific article

Dissection of the IgE and T-cell recognition of the major group 5 grass pollen allergen Phl p 5.

scientific article published on 31 October 2013

Division of the major birch pollen allergen, Bet v 1, into two non-anaphylactic fragments.

scientific article

Doctor, I Think I Am Suffering from MCAS: Differential Diagnosis and Separating Facts from Fiction

scientific article published on 01 April 2019

Does cord blood contain enough progenitor cells for transplantation?

scientific article published in January 1994

Does high-dose cytarabine cause cumulative toxicity in patients undergoing consolidation therapy for acute myeloid leukemia?

scientific article published on 02 May 2013

Dose study of the multikinase inhibitor, LY2457546, in patients with relapsed acute myeloid leukemia to assess safety, pharmacokinetics, and pharmacodynamics

scientific article

Drug-induced inhibition of phosphorylation of STAT5 overrides drug resistance in neoplastic mast cells.

scientific article published on 29 November 2017

E- and p-selectins are essential for repopulation of chronic myelogenous and chronic eosinophilic leukemias in a scid mouse xenograft model

scientific article

Effects of cyclosporin A and FK-506 on stem cell factor-induced histamine secretion and growth of human mast cells

scientific article published on 01 August 1996

Effects of dental amalgam and heavy metal cations on cytokine production by peripheral blood mononuclear cellsin vitro

scientific article published on 01 October 1998

Effects of ibrutinib on proliferation and histamine release in canine neoplastic mast cells

scientific article published on 13 August 2019

Effects of interferon-alpha2b treatment on ex vivo differentiation of mast cells from circulating progenitor cells in a patient with systemic mastocytosis.

scientific article published on December 2000

Effects of the CD33-targeted drug gemtuzumab ozogamicin (Mylotarg) on growth and mediator secretion in human mast cells and blood basophils.

scientific article published on January 2007

Efficacy and Safety of Midostaurin in Advanced Systemic Mastocytosis

scientific article (publication date: 30 June 2016)

Elevated tryptase levels selectively cluster in myeloid neoplasms: a novel diagnostic approach and screen marker in clinical haematology

scientific article published on 12 June 2009

Emerging stem cell concepts for imatinib-resistant chronic myeloid leukaemia: implications for the biology, management, and therapy of the disease.

scientific article published on 05 June 2008

Emerging therapeutic targets in myeloproliferative neoplasms and peripheral T-cell leukemia and lymphomas

scientific article published on 17 November 2017

Emerging translational science discoveries, clonal approaches, and treatment trends in chronic myeloproliferative neoplasms

scientific article published on 20 June 2019

Endogenous erythroid colony formation in chronic myeloid leukemia: a recurrent finding associated with persistent minimal residual disease under imatinib.

scientific article published on 4 September 2013

Enumeration and immunohistochemical characterisation of bone marrow basophils in myeloproliferative disorders using the basophil specific monoclonal antibody 2D7.

scientific article published on 3 February 2006

Eosinophilia in systemic mastocytosis: clinical and molecular correlates and prognostic significance

scientific article published on 23 April 2007

Epitope specificity determines cross-protection of a SIT-induced IgG4 antibody

scientific article

Evaluation of angiogenesis and vascular endothelial growth factor expression in the bone marrow of patients with aplastic anemia.

scientific article

Evaluation of antileukaemic effects of rapamycin in patients with imatinib-resistant chronic myeloid leukaemia.

scientific article published in January 2008

Evaluation of biologic activity of tryptase secreted from blast cells in acute myeloid leukemia.

scientific article

Evaluation of cooperative antileukemic effects of nilotinib and vildagliptin in Ph+ chronic myeloid leukemia

scientific article published on 12 October 2017

Evaluation of in vitro effects of various targeted drugs on plasma cells and putative neoplastic stem cells in patients with multiple myeloma.

scientific article published on 25 August 2016

Evaluation of in vivo antineoplastic effects of rapamycin in patients with chemotherapy-refractory AML.

scientific article published on 7 October 2009

Evaluation of mast cell activation syndromes: impact of pathology and immunohistology.

scientific article published on 27 April 2012

Evaluation of neoplastic human mast cells by tryptase-immunoelectron microscopy.

scientific article published in February 2006

Evaluation of normal and neoplastic human mast cells for expression of CD172a (SIRPalpha), CD47, and SHP-1.

scientific article

Evaluation of treatment responses and colony-forming progenitor cells in 50 patients with aplastic anemia after immunosuppressive therapy or hematopoietic stem cell transplantation: a single-center experience.

scientific article published on 18 January 2014

Exploring the curative potential of BCR-ABL1-targeting drugs for chronic myeloid leukaemia.

scientific article published on 19 October 2010

Expression and prognostic significance of different mRNA 5'-end variants of the oncogene EVI1 in 266 patients with de novo AML: EVI1 and MDS1/EVI1 overexpression both predict short remission duration

scientific article

Expression of CD25 on leukemic stem cells in BCR-ABL1+ CML: Potential diagnostic value and functional implications.

scientific article published on 27 April 2017

Expression of a Major Plant Allergen as Membrane-Anchored and Secreted Protein in Human Cells with Preserved T Cell and B Cell Epitopes

article

Expression of cell surface antigens on mast cells: mast cell phenotyping.

scientific article published in January 2006

Expression of fibrinolytic antigens in redistributed cardiac mast cells in auricular thrombosis

scientific article published on 01 November 1997

Expression of homing receptors and related molecules on human mast cells and basophils: a comparative analysis using multi-color flow cytometry and toluidine blue/immunofluorescence staining techniques.

scientific article

Expression of mast cell tryptase by myeloblasts in a group of patients with acute myeloid leukemia.

scientific article published in October 2001

Expression of the C5a receptor (CD88) on synovial mast cells in patients with rheumatoid arthritis

scientific article published on 01 February 1998

Expression of the target receptor CD33 in CD34+/CD38-/CD123+ AML stem cells

scientific article published on 01 January 2007

Expression, epitope analysis, and functional role of the LFA-2 antigen detectable on neoplastic mast cells.

scientific article

Extensive pleural and pericardial effusion in chronic myeloid leukemia during treatment with dasatinib at 100 mg or 50 mg daily

scientific article

Extracorporeal IgE Immunoadsorption in Allergic Asthma: Safety and Efficacy.

scientific article published on 12 February 2017

FDG positron emission tomography in patients with systemic mastocytosis.

scientific article published in November 2002

FIP1L1/PDGFRA is a molecular marker of chronic eosinophilic leukaemia but not for systemic mastocytosis.

scientific article published in February 2007

Familial hypertryptasemia with associated mast cell activation syndrome.

scientific article published on 30 July 2014

Fatty acid synthase is a metabolic marker of cell proliferation rather than malignancy in ovarian cancer and its precursor cells.

scientific article published on 3 November 2014

Fetuin in human bone marrow: detection in foetal tissue and patients with mastocytosis

scientific article published on 01 August 2001

First-in-human response of BCL-2 inhibitor venetoclax in T-cell prolymphocytic leukemia.

scientific article published on 27 September 2017

Formation of disulfide bonds and homodimers of the major cat allergen Fel d 1 equivalent to the natural allergen by expression in Escherichia coli.

scientific article

Frequent occurrence of T cell-mediated late reactions revealed by atopy patch testing with hypoallergenic rBet v 1 fragments.

scientific article published on 28 October 2015

Functional characterization, localization, and inhibitor sensitivity of the TPR-FGFR1 fusion in 8p11 myeloproliferative syndrome.

scientific article published on 22 September 2015

Fusion proteins consisting of Bet v 1 and Phl p 5 form IgE-reactive aggregates with reduced allergenic activity

scientific article published on 08 March 2019

Gene expression and mutation-guided synthetic lethality eradicates proliferating and quiescent leukemia cells

scientific article published on 8 May 2017

Generation of an allergy vaccine by disruption of the three-dimensional structure of the cross-reactive calcium-binding allergen, Phl p 7.

scientific article published on May 2004

Genetic engineering of a hypoallergenic trimer of the major birch pollen allergen Bet v 1

scientific article published on 24 July 2001

Genetic engineering of recombinant hypoallergenic oligomers of the major birch pollen allergen, Bet v 1: candidates for specific immunotherapy

scientific article published on 01 February 1999

Genetic engineering of trimers of hypoallergenic fragments of the major birch pollen allergen, Bet v 1, for allergy vaccination

scientific article

Gliotoxin Targets Nuclear NOTCH2 in Human Solid Tumor Derived Cell Lines In Vitro and Inhibits Melanoma Growth in Xenograft Mouse Model

scientific article

Gliotoxin is a potent NOTCH2 transactivation inhibitor and efficiently induces apoptosis in chronic lymphocytic leukaemia (CLL) cells.

scientific article

Glucocorticosteroids rescue basophils from dasatinib-augmented immunoglobulin E-mediated histamine release.

scientific article

Growth-inhibitory effects of four tyrosine kinase inhibitors on neoplastic feline mast cells exhibiting a Kit exon 8 ITD mutation.

scientific article

Heterogeneity of neoplastic stem cells: theoretical, functional, and clinical implications.

scientific article published on 23 January 2013

High activation of STAT5A drives peripheral T-cell lymphoma and leukemia

scientific article published on 31 January 2020

High dose intermittent ARA-C (HiDAC) for consolidation of patients with de novo AML: a single center experience.

scientific article published on 25 January 2005

High frequency of concomitant mastocytosis in patients with acute myeloid leukemia exhibiting the transforming KIT mutation D816V.

scientific article published on 24 April 2010

High level expression of birch pollen profilin (Bet v 2) in Escherichia coli: purification and characterization of the recombinant allergen.

scientific article

High-level expression in Escherichia coli and purification of recombinant plant profilins: comparison of IgE-binding capacity and allergenic activity

scientific article published on 01 September 1996

Histopathological and immunohistochemical aspects of mastocytosis.

scientific article

Hitting two oncogenic machineries in cancer cells: cooperative effects of the multi-kinase inhibitor ponatinib and the BET bromodomain blockers JQ1 or dBET1 on human carcinoma cells.

scientific article published on 29 May 2018

How I treat patients with advanced systemic mastocytosis.

scientific article

Human erythroleukemia genetics and transcriptomes identify master transcription factors as functional disease drivers

scientific article published on 29 April 2020

Human leukaemic stem cells: a novel target of therapy.

scientific article published in August 2004

Hymenoptera-venom-induced upregulation of the basophil activation marker ecto-nucleotide pyrophosphatase/phosphodiesterase 3 in sensitized individuals.

scientific article published in December 2001

Hyperfibrinolysis in a case of myelodysplastic syndrome with leukemic spread of mast cells

scientific article published on 01 May 1999

Hypoallergenic derivatives of Fel d 1 obtained by rational reassembly for allergy vaccination and tolerance induction.

scientific article published on June 2014

Hypoallergenic derivatives of the major birch pollen allergen Bet v 1 obtained by rational sequence reassembly.

scientific article

Hypofibrinogenemia in non-M3 acute myeloid leukemia. Incidence, clinical and laboratory characteristics and prognosis ⬇️

scientific article published on August 1, 1998

ICON: Eosinophil Disorders ⬇️

scientific article published on December 1, 2012

ICUS, IDUS, CHIP and CCUS: Diagnostic Criteria, Separation from MDS and Clinical Implications

scientific article published on 01 June 2018

IL-3 promotes basophilic differentiation of KU812 cells through high affinity binding sites.

scientific article published on September 1990

IL-4 downregulates expression of the target receptor CD30 in neoplastic canine mast cells.

scientific article published on 9 August 2016

Ibuprofen inhibits pyrogen-dependent expression of VCAM-1 and ICAM-1 on human endothelial cells

scientific article published on 01 January 1996

Identification of CD13, CD107a, and CD164 as novel basophil-activation markers and dissection of two response patterns in time kinetics of IgE-dependent upregulation

scientific article

Identification of Der p 23, a peritrophin-like protein, as a new major Dermatophagoides pteronyssinus allergen associated with the peritrophic matrix of mite fecal pellets.

scientific article

Identification of MCL1 as a novel target in neoplastic mast cells in systemic mastocytosis: inhibition of mast cell survival by MCL1 antisense oligonucleotides and synergism with PKC412.

scientific article published on April 2007

Identification of Ponatinib as a potent inhibitor of growth, migration, and activation of neoplastic eosinophils carrying FIP1L1-PDGFRA

scientific article

Identification of Profilin as a Novel Pollen Allergen; IgE Autoreactivity in Sensitized Individuals ⬇️

scientific article published on August 2, 1991

Identification of a leukemia-initiating stem cell in human mast cell leukemia

scientific article published on 05 April 2019

Identification of bromodomain-containing protein-4 as a novel marker and epigenetic target in mast cell leukemia

scientific article published on 9 June 2015

Identification of campath-1 (CD52) as novel drug target in neoplastic stem cells in 5q-patients with MDS and AML.

scientific article published on 5 May 2014

Identification of common allergenic structures in mugwort and ragweed pollen

scientific article published on 01 February 1998

Identification of heat shock protein 32 (Hsp32) as a novel survival factor and therapeutic target in neoplastic mast cells.

scientific article published on 9 April 2007

Identification of heat shock protein 32 (Hsp32) as a novel target in acute lymphoblastic leukemia

scientific article published on March 2014

Identification of mTOR as a novel bifunctional target in chronic myeloid leukemia: dissection of growth-inhibitory and VEGF-suppressive effects of rapamycin in leukemic cells.

scientific article published on 22 March 2005

Identification of mcl-1 as a BCR/ABL-dependent target in chronic myeloid leukemia (CML): evidence for cooperative antileukemic effects of imatinib and mcl-1 antisense oligonucleotides.

scientific article

Identification of oncostatin M as a STAT5-dependent mediator of bone marrow remodeling in KIT D816V-positive systemic mastocytosis

scientific article

Identification of the Ki-1 antigen (CD30) as a novel therapeutic target in systemic mastocytosis.

scientific article

Idiopathic cytopenia of undetermined significance (ICUS) and idiopathic dysplasia of uncertain significance (IDUS), and their distinction from low risk MDS ⬇️

scientific article published on September 13, 2011

Idiopathic cytopenia of undetermined significance (ICUS) versus low risk MDS: the diagnostic interface.

scientific article

IgA autoreactivity: a feature common to inflammatory bowel and connective tissue diseases

scientific article published on 01 April 2002

IgG subclass reactivity to human cardiac myosin in cardiomyopathy patients is indicative of a Th1-like autoimmune disease

scientific article published on 01 February 1999

Image-based ex-vivo drug screening for patients with aggressive haematological malignancies: interim results from a single-arm, open-label, pilot study

scientific article published on 15 November 2017

Imatinib-resistant chronic myeloid leukemia (CML): Current concepts on pathogenesis and new emerging pharmacologic approaches.

scientific article published in December 2007

Immunization with purified natural and recombinant allergens induces mouse IgG1 antibodies that recognize similar epitopes as human IgE and inhibit the human IgE-allergen interaction and allergen-induced basophil degranulation.

scientific article published in June 1998

Immunoglobulin E response to human proteins in atopic patients

scientific article published on 01 August 1996

Immunohistochemical assessment of CD25 is equally sensitive and diagnostic in mastocytosis compared to flow cytometry.

scientific article published on 20 March 2008

Immunohistochemical detection of VEGF in the bone marrow of patients with acute myeloid leukemia. Correlation between VEGF expression and the FAB category.

scientific article published in May 2003

Immunohistochemical detection of VEGF in the bone marrow of patients with chronic myeloid leukemia and correlation with the phase of disease.

scientific article published in April 2004

Immunohistochemical detection of histidine decarboxylase in neoplastic mast cells in patients with systemic mastocytosis.

scientific article published on 7 February 2006

Immunologic characterization of purified recombinant timothy grass pollen (Phleum pratense) allergens (Phl p 1, Phl p2, Phl p 5)

scientific article published on 01 March 1996

Immunological characterization and antibacterial function of persisting granulocytes in leukemic patients receiving pulse cytosine arabinoside-consolidation chemotherapy on days 1, 3, and 5.

scientific article published in February 2006

Immunophenotypic analysis of HL-60 cells during basophilic differentiation

scientific article published on 01 July 1996

Immunophenotypic characterization of human bone marrow endosteal cells

scientific article published on 01 June 1999

Immunotherapy-Based Targeting and Elimination of Leukemic Stem Cells in AML and CML ⬇️

scientific article published on 29 August 2019

Impact of adjunct cytogenetic abnormalities for prognostic stratification in patients with myelodysplastic syndrome and deletion 5q

scientific article published on 30 September 2010

Impact of cytogenetics on the prognosis of adults with de novo AML in first relapse

scientific article published on 01 February 2004

Implications of STAT3 and STAT5 signaling on gene regulation and chromatin remodeling in hematopoietic cancer

article

Improved outcome in patients with chronic myelogenous leukemia after allogeneic hematopoietic stem cell transplantation over the past 25 years: a single-center experience.

scientific article published in July 2010

Improvement of cardiac function, mitral regurgitation and pulmonary hypertension in a patient with chronic eosinophilic leukemia (CEL) after low dose imatinib therapy.

scientific article published on 15 April 2008

In human macrophages the complement component C5a induces the expression of oncostatin M via AP-1 activation.

scientific article

In vitro and in vivo effects of JAK2 inhibition in chronic myelomonocytic leukemia

scientific article published on 9 May 2016

In vitro and in vivo studies of three radiolabelled somatostatin analogues:123I-Octreotide (OCT),123I-Tyr-3-OCT and111In-TIRA-d-Phe-1-OCT

scientific article published on 01 October 1996

In vitro effects of histamine receptor 1 antagonists on proliferation and histamine release in canine neoplastic mast cells

scientific article published on 13 September 2020

In vivo effects of imatinib mesylate on human haematopoietic progenitor cells.

scientific article

Increase of bone marrow lymphocytes in systemic mastocytosis: reactive lymphocytosis or malignant lymphoma? Immunohistochemical and molecular findings on routinely processed bone marrow biopsy specimens.

scientific article published on August 2003

Increased angiogenesis in the bone marrow of patients with systemic mastocytosis.

scientific article published on May 2002

Individual hymenoptera venom compounds induce upregulation of the basophil activation marker ectonucleotide pyrophosphatase/phosphodiesterase 3 (CD203c) in sensitized patients.

scientific article published in October 2002

Individualized management and therapy of myelodysplastic syndromes

scientific article

Indolent systemic mastocytosis associated with atypical small lymphocytic lymphoma: a rare form of concomitant lymphoproliferative disease.

scientific article published on 2 May 2008

Indolent systemic mastocytosis with elevated serum tryptase, absence of skin lesions, and recurrent severe anaphylactoid episodes.

scientific article published on 17 February 2005

Induction of IgE antibodies with predefined specificity in rhesus monkeys with recombinant birch pollen allergens, Bet v 1 and Bet v 2

scientific article published on 01 January 1996

Induction of antibody responses to new B cell epitopes indicates vaccination character of allergen immunotherapy

scientific article published on 01 June 1999

Induction of apoptosis in the human mast cell leukemia cell line HMC-1 by various antineoplastic drugs.

scientific article published on March 2003

Induction of specific histamine release from basophils with purified natural and recombinant birch pollen allergens.

scientific article

Inhalation scintigraphy with iodine-123-labeled interferon gamma-1b: pulmonary deposition and dose escalation study in healthy volunteers

scientific article published on 01 September 1997

Inhibition of STAT5: a therapeutic option in BCR-ABL1-driven leukemia

scientific article

Inhibition of allergen-induced histamine release from human basophils by cyclosporine A and FK-506

scientific article published on 01 September 1997

Inhibition of stem cell factor dependent formation of human mast cells by interleukin-3 and interleukin-4

scientific article published on 01 November 1994

Intensive consolidation with G-CSF support: Tolerability, safety, reduced hospitalization, and efficacy in acute myeloid leukemia patients ≥60 years.

scientific article published on 11 July 2017

Interleukin 3 activates human blood basophils via high-affinity binding sites.

scientific article

Interleukin 4 promotes expression of mast cell ICAM-1 antigen ⬇️

scientific article published on April 15, 1991

Interleukin-13 promoter gene polymorphism -1112C/T is associated with the systemic form of mastocytosis

scientific article

Interleukin-3 promotes the expression of E-NPP3/CD203C on human blood basophils in healthy subjects and in patients with birch pollen allergy.

scientific article

Interleukin-33: a regulator of basophils

scientific article published on 01 February 2009

International Working Group-Myeloproliferative Neoplasms Research and Treatment (IWG-MRT) & European Competence Network on Mastocytosis (ECNM) consensus response criteria in advanced systemic mastocytosis.

scientific article published on 16 January 2013

Intranasal administration of allergen increases specific IgE whereas intranasal omalizumab does not increase serum IgE levels-A pilot study.

scientific article

Iron overload in myelodysplastic syndromes (MDS) - diagnosis, management, and response criteria: a proposal of the Austrian MDS platform

scientific article published on 24 January 2008

Is ruxolitinib a potentially useful drug in hematological malignancies with RAS pathway hyperactivation?

scientific article published on December 2016

Isolation of a high-affinity Bet v 1-specific IgG-derived ScFv from a subject vaccinated with hypoallergenic Bet v 1 fragments.

scientific article published on 20 February 2018

Isolation of an immunodominant IgE hapten from an epitope expression cDNA library. Dissection of the allergic effector reaction.

scientific article published on November 1994

KIT D816 mutated/CBF-negative acute myeloid leukemia: a poor-risk subtype associated with systemic mastocytosis

scientific article published on 11 January 2019

KIT D816V and the cytokine storm in mastocytosis: production and role of interleukin-6

scientific article published on 01 January 2020

KIT mutation analysis in mast cell neoplasms: recommendations of the European Competence Network on Mastocytosis

scientific article

KIT polymorphisms and mutations determine responses of neoplastic mast cells to bafetinib (INNO-406).

scientific article published on 26 May 2010

Karyotype plus NPM1 mutation status defines a group of elderly patients with AML (≥60 years) who benefit from intensive post-induction consolidation therapy

scientific article published on 19 September 2016

Kit and c-kit mutations in mastocytosis: a short overview with special reference to novel molecular and diagnostic concepts.

scientific article

Large maculopapular cutaneous lesions are associated with favorable outcome in childhood-onset mastocytosis.

scientific article

Lenalidomide therapy in systemic mastocytosis.

scientific article published on 21 July 2008

Liposomal cytarabine for treatment of myeloid central nervous system relapse in chronic myeloid leukaemia occurring during imatinib therapy

scientific article published on 28 August 2007

Location of a VIPoma by iodine-123-vasoactive intestinal peptide scintigraphy

scientific article published on 01 September 1998

Long-term treatment with imatinib results in profound mast cell deficiency in Ph+ chronic myeloid leukemia

scientific article published on February 2015

Low blood counts: immune mediated, idiopathic, or myelodysplasia.

scientific article published on January 2012

Low erythropoietin production as non-oncogenic co-factor contributing to disease-manifestation in low-risk MDS: a hypothesis supported by unique case reports.

scientific article published on 15 April 2008

Low-level expression of proapoptotic Bcl-2-interacting mediator in leukemic cells in patients with chronic myeloid leukemia: role of BCR/ABL, characterization of underlying signaling pathways, and reexpression by novel pharmacologic compounds.

scientific article

Ludwig Boltzmann Cluster Oncology (LBC ONC): first 10 years and future perspectives

scientific article published on 13 July 2018

MLL-fusion-driven leukemia requires SETD2 to safeguard genomic integrity.

scientific article published on 18 May 2018

Maintenance therapy with histamine plus IL-2 induces a striking expansion of two CD56bright NK cell subpopulations in patients with acute myeloid leukemia and supports their activation

scientific article published on 21 June 2016

Major response of PNH to an AML chemotherapy protocol

scientific article published on 22 March 2018

Massive release of the histamine-degrading enzyme diamine oxidase during severe anaphylaxis in mastocytosis patients

scientific article published on 01 January 2019

Mast Cells, Mastocytosis, and Related Disorders

scientific article published on July 2015

Mast cell activation syndrome: Importance of consensus criteria and call for research

scientific article published on 19 June 2018

Mast cell activation syndrome: Proposed diagnostic criteria.

scientific article

Mast cell activation syndromes: definition and classification.

scientific article

Mast cell-derived proteases control allergic inflammation through cleavage of IgE

scientific article published on 29 September 2007

Mast cell-lineage versus basophil lineage involvement in myeloproliferative and myelodysplastic syndromes: diagnostic role of cell-immunophenotyping.

scientific article published on July 1996

Mast cells are augmented in deep vein thrombosis and express a profibrinolytic phenotype

scientific article published on 01 February 1999

Mastocytosis: 2016 updated WHO classification and novel emerging treatment concepts

scientific article published on 28 December 2016

Mastocytosis: a disease of the hematopoietic stem cell

scientific article published on 03 October 2008

Mastocytosis: immunophenotypical features of the transformed mast cells are unique among hematopoietic cells

scientific article published on May 2014

Mechanisms, safety and efficacy of a B cell epitope-based vaccine for immunotherapy of grass pollen allergy

scientific article published on 20 August 2016

Mediator-Related Symptoms and Anaphylaxis in Children with Mastocytosis

scientific article published on 7 March 2021

Mediator-Related Symptoms and Anaphylaxis in Children with Mastocytosis

scientific article published in February 2021

Mesenchymal Stem and Progenitor Cells in Normal and Dysplastic Hematopoiesis-Masters of Survival and Clonality?

scientific article

Metabolic drug survey highlights cancer cell dependencies and vulnerabilities

scientific article published in 2021

Microarray-based Detection of Allergen-Reactive IgE in Patients with Mastocytosis

scientific article published on 26 April 2020

Midostaurin: a magic bullet that blocks mast cell expansion and activation

scientific article published on 30 August 2017

Molecular Aspects of Allergens and Allergy.

scientific article

Molecular Background, Clinical Features and Management of Pediatric Mastocytosis: Status 2021

scientific article published on 4 March 2021

Molecular Basis and Clinical Application of Growth-Factor-Independent In Vitro Myeloid Colony Formation in Chronic Myelomonocytic Leukemia

scientific article published on 22 August 2020

Molecular and functional characterization of the urokinase receptor on human mast cells.

scientific article published on March 1997

Molecular and immunologic characterization of a highly cross-reactive two EF-hand calcium-binding alder pollen allergen, Aln g 4: structural basis for calcium-modulated IgE recognition.

scientific article

Molecular and immunological characterization of a novel timothy grass (Phleum pratense) pollen allergen, Phl p 11.

scientific article published in September 2002

Molecular and immunological characterization of arginine kinase from the Indianmeal moth, Plodia interpunctella, a novel cross-reactive invertebrate pan-allergen.

scientific article

Molecular characterization of an autoallergen, Hom s 1, identified by serum IgE from atopic dermatitis patients

scientific article

Molecular evolution of hypoallergenic hybrid proteins for vaccination against grass pollen allergy.

scientific article published on 18 March 2015

Molecular profiling of myeloid progenitor cells in multi-mutated advanced systemic mastocytosis identifies KIT D816V as a distinct and late event.

scientific article published on 8 January 2015

Molecular quantification of tissue disease burden is a new biomarker and independent predictor of survival in mastocytosis

scientific article published on 31 January 2020

Molecular, Structural and Immunological Characterization of Der p 18, a Chitinase-Like House Dust Mite Allergen

scientific article

Monoclonal B-cell lymphocytosis (MBL) with normal lymphocyte counts is associated with decreased numbers of normal circulating B-cell subsets

scientific article published on 08 June 2012

Monosomal karyotype in MDS: explaining the poor prognosis?

scientific article published on 21 June 2013

Morphologic and immunophenotypic properties of neoplastic cells in a case of mast cell sarcoma

scientific article (publication date: July 2003)

Morphologic properties of neoplastic mast cells: delineation of stages of maturation and implication for cytological grading of mastocytosis

scientific article published on 01 July 2001

Multi-level suppression of receptor-PI3K-mTORC1 by fatty acid synthase inhibitors is crucial for their efficacy against ovarian cancer cells

scientific article published on 10 January 2017

Multidisciplinary Challenges in Mastocytosis and How to Address with Personalized Medicine Approaches

scientific article published on 18 June 2019

Multidisciplinary Management of Mastocytosis: Nordic Expert Group Consensus

scientific article published on 22 December 2015

Mutation analysis of C-KIT in patients with myelodysplastic syndromes without mastocytosis and cases of systemic mastocytosis.

scientific article published in May 2001

Myelodysplastic syndromes, aging, and age: correlations, common mechanisms, and clinical implications.

scientific article published on October 2007

Myeloid leukemias express a broad spectrum of VEGF receptors including neuropilin-1 (NRP-1) and NRP-2.

scientific article

Myeloproliferative neoplasms and inflammation: whether to target the malignant clone or the inflammatory process or both

scientific article published on 8 February 2016

NDEL1-PDGFRB fusion gene in a myeloid malignancy with eosinophilia associated with resistance to tyrosine kinase inhibitors

scientific article published on 30 August 2016

NI-1: a novel canine mastocytoma model for studying drug resistance and IgER-dependent mast cell activation. ⬇️

scientific article published on 15 May 2012

NOTCH2 links protein kinase C delta to the expression of CD23 in chronic lymphocytic leukaemia (CLL) cells.

scientific article published on 8 December 2009

NOX4-driven ROS formation mediates PTP inactivation and cell transformation in FLT3ITD-positive AML cells

scientific article published on 26 August 2015

Neoplastic stem cells: current concepts and clinical perspectives.

scientific article published on 25 February 2010

New Comprehensive Cytogenetic Scoring System for Primary Myelodysplastic Syndromes (MDS) and Oligoblastic Acute Myeloid Leukemia After MDS Derived From an International Database Merge ⬇️

scientific article published on February 13, 2012

New developments in the field of mastocytosis and mast cell activation syndromes: a summary of the Annual Meeting of the European Competence Network on Mastocytosis (ECNM) 2019

scientific article published on 26 December 2019

New insights into the pathogenesis of the hyperimmunoglobulinaemia E syndrome

scientific article published on 01 November 2005

New insights into the prognostic impact of the karyotype in MDS and correlation with subtypes: evidence from a core dataset of 2124 patients

scientific article published on 28 August 2007

Next-generation sequencing identifies major DNA methylation changes during progression of Ph+ chronic myeloid leukemia

scientific article published on 23 May 2016

Nilotinib and imatinib are comparably effective in reducing growth of human eosinophil leukemia cells in a newly established xenograft model

scientific article

Nilotinib as frontline and second-line therapy in chronic myeloid leukemia: open questions.

scientific article published on 07 September 2011

Nilotinib is superior to imatinib as first-line therapy of chronic myeloid leukemia: the ENESTnd study.

scientific article published on 9 November 2010

Nilotinib-induced vasculopathy: identification of vascular endothelial cells as a primary target site.

scientific article published on 31 July 2017

Non-NAD-like PARP1 inhibitor enhanced synthetic lethal effect of NAD-like PARP inhibitors against BRCA1-deficient leukemia

scientific article published on 02 October 2018

Non-anaphylactic surface-exposed peptides of the major birch pollen allergen, Bet v 1, for preventive vaccination.

scientific article published in October 2004

Normal ABL1 is a tumor suppressor and therapeutic target in human and mouse leukemias expressing oncogenic ABL1 kinases

scientific article published on 10 February 2016

Normal and pathological erythropoiesis in adults: from gene regulation to targeted treatment concepts

article

Normal bone marrow function over 6 years in a patient with dysplastic hematopoiesis and a complex karyotype.

scientific article published in June 2004

Novel targeted therapies for eosinophil-associated diseases and allergy

scientific article

Numbers of colony-forming progenitors in patients with systemic mastocytosis: potential diagnostic implications and comparison with myeloproliferative disorders

scientific article published on 01 July 2003

O-GlcNAcylation of STAT5 controls tyrosine phosphorylation and oncogenic transcription in STAT5-dependent malignancies

scientific article published on 11 January 2017

On the way to targeted therapy of mast cell neoplasms: identification of molecular targets in neoplastic mast cells and evaluation of arising treatment concepts.

scientific article published in August 2004

Overexpression of complement receptors and related antigens on the surface of bone marrow mast cells in patients with systemic mastocytosis

scientific article published on 01 January 2003

Palbociclib treatment of FLT3-ITD+ AML cells uncovers a kinase-dependent transcriptional regulation of FLT3 and PIM1 by CDK6.

scientific article published on 20 April 2016

Pathogenesis, classification and treatment of mastocytosis: state of the art in 2010 and future perspectives.

scientific article published on August 2010

Pathogenesis, classification, and treatment of myelodysplastic syndromes (MDS).

scientific article

Pathogenesis, clinical features, and treatment advances in mastocytosis.

scientific article published on January 2006

Paul Ehrlich (1854-1915) and His Contributions to the Foundation and Birth of Translational Medicine.

scientific article

Peripheral arterial disease outcomes and association with suPAR: A bridge to myeloid precursors or mast cells or both?

scientific article published on 8 July 2017

Pharmacologic inhibition of STAT5 in acute myeloid leukemia

scientific article published on 2 February 2018

Phenotypic Characterization of Human Skin Mast Cells by Combined Staining with Toluidine Blue and CD Antibodies ⬇️

scientific article published on October 1, 1998

Phenotyping and Target Expression Profiling of CD34+/CD38- and CD34+/CD38+ Stem- and Progenitor cells in Acute Lymphoblastic Leukemia.

scientific article published on 15 May 2018

Phenotyping of human melanoma cells reveals a unique composition of receptor targets and a subpopulation co-expressing ErbB4, EPO-R and NGF-R.

scientific article published on 29 January 2014

Phorbol ester 12-O-tetradecanoylphorbol-13-acetate down-regulates expression of the c-kit proto-oncogene product

scientific article published on 01 September 1993

Possible therapeutic potential of a recombinant group 2 grass pollen allergen-specific antibody fragment.

scientific article published on 20 November 2013

Preclinical human models and emerging therapeutics for advanced systemic mastocytosis

scientific article published on 05 July 2018

Prevention of latex allergy by selection of low-allergen gloves

scientific article published on 01 April 2000

Probability of remaining in unsustained complete remission after steroid therapy withdrawal in patients with primary warm-antibody reactive autoimmune hemolytic anemia.

scientific article

Profilins constitute a novel family of functional plant pan-allergens.

scientific article published on February 1992

Prognosis of patients with a second relapse of acute myeloid leukemia.

scientific article published in December 2000

Prognostic factors for intensive care unit admission, intensive care outcome, and post-intensive care survival in patients with de novo acute myeloid leukemia: a single center experience ⬇️

scientific article published on November 11, 2010

Prognostic impact of age and gender in 897 untreated patients with primary myelodysplastic syndromes.

scientific article published on 15 July 2009

Prognostic impact of blast cell counts in dysplastic bone marrow disorders (MDS and CMML I) with concomitant fibrosis.

scientific article published on 17 November 2013

Prognostic impact of eosinophils in mastocytosis: analysis of 2350 patients collected in the ECNM Registry

scientific article published on 18 November 2019

Progressive peripheral arterial occlusive disease and other vascular events during nilotinib therapy in CML.

scientific article published on 27 April 2011

Proposed Diagnostic Algorithm for Patients with Suspected Mast Cell Activation Syndrome

scientific article published on 05 February 2019

Proposed Terminology and Classification of Pre-Malignant Neoplastic Conditions: A Consensus Proposal

scientific article published on 26 November 2017

Proposed diagnostic algorithm for patients with suspected mastocytosis: a proposal of the European Competence Network on Mastocytosis.

scientific article published on 19 May 2014

Proposed diagnostic criteria and classification of basophilic leukemias and related disorders

scientific article published on 16 January 2017

Proposed diagnostic criteria for classical chronic myelomonocytic leukemia (CMML), CMML variants and pre-CMML conditions

scientific article published on 02 May 2019

Proteome analysis identifies L1CAM/CD171 and DPP4/CD26 as novel markers of human skin mast cells

scientific article

Purification of human basophils and mast cells by multistep separation technique and mAb to CDw17 and CD117/c-kit

scientific article published on 01 May 1995

Purification, structural and immunological characterization of a timothy grass (Phleum pratense) pollen allergen, Phl p 4, with cross-reactive potential.

scientific article published in September 2002

Quantification of human diamine oxidase.

scientific article published on 29 December 2016

Quantitative assessment of the CD26+ leukemic stem cell compartment in chronic myeloid leukemia: patient-subgroups, prognostic impact, and technical aspects.

scientific article published on 29 April 2016

Quantitative, phenotypic, and functional evaluation of basophils in myelodysplastic syndromes ⬇️

scientific article published on October 1, 2001

RAS mutations drive proliferative chronic myelomonocytic leukemia via a KMT2A-PLK1 axis

scientific article published on 18 May 2021

RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia

scientific article (publication date: 3 August 2011)

Rapid identification of compound mutations in patients with Philadelphia-positive leukaemias by long-range next generation sequencing.

scientific article published on 20 December 2013

Recognition sites for microbes and components of the immune system on human mast cells: relationship to CD antigens and implications for host defense.

scientific article published on July 2007

Recombinant allergens promote expression of aminopeptidase-n (CD13) on basophils in allergic patients.

scientific article published in January 2008

Recombinant carp parvalbumin, the major cross-reactive fish allergen: a tool for diagnosis and therapy of fish allergy.

scientific article

Recombinant human megakaryocyte growth and development factor increases levels of circulating haemopoietic progenitor cells post chemotherapy in patients with acute myeloid leukaemia ⬇️

scientific article published on July 1, 1998

Redistribution, homing and organ-invasion of neoplastic stem cells in myeloid neoplasms

scientific article published on 10 August 2019

Reducing allergenicity by altering allergen fold: a mosaic protein of Phl p 1 for allergy vaccination.

scientific article

Reduction of the in vivo allergenicity of Der p 2, the major house-dust mite allergen, by genetic engineering.

scientific article published on 4 March 2008

Refined diagnostic criteria and classification of mast cell leukemia (MCL) and myelomastocytic leukemia (MML): a consensus proposal

scientific article

Refinements in response criteria in systemic mastocytosis: reply to a proposal

scientific article published on 26 April 2010

Response to therapy with interferon alpha-2b and prednisolone in aggressive systemic mastocytosis: report of five cases and review of the literature.

scientific article published on March 2004

Results from a Genome-Wide Association Study (GWAS) in Mastocytosis Reveal New Gene Polymorphisms Associated with WHO Subgroups

scientific article published on 31 July 2020

Revealing the pathogenesis of the 5q- syndrome

scientific article published on 01 August 2008

Revisiting guidelines for integration of flow cytometry results in the WHO classification of myelodysplastic syndromes-proposal from the International/European LeukemiaNet Working Group for Flow Cytometry in MDS.

scientific article

Risk and Management of Patients with Mastocytosis and MCAS in the SARS-CoV-2 (COVID-19) Pandemic: Expert Opinions

scientific article published on 16 June 2020

Risk factors and management of severe life-threatening anaphylaxis in patients with clonal mast cell disorders

scientific article published on July 2014

Risk factors and mechanisms contributing to TKI-induced vascular events in patients with CML.

scientific article published on 12 May 2017

Role of interleukins in the regulation of basophil development and secretion.

scientific article published on January 2010

SETD2 and histone H3 lysine 36 methylation deficiency in advanced systemic mastocytosis

scientific article

STAT5 is Expressed in CD34+/CD38- Stem Cells and Serves as a Potential Molecular Target in Ph-Negative Myeloproliferative Neoplasms

scientific article published on 21 April 2020

STAT5BN642H is a driver mutation for T cell neoplasia

scientific article published on 4 December 2017

Serum tryptase levels in patients with mastocytosis: correlation with mast cell burden and implication for defining the category of disease.

scientific article

Severe life-threatening or disabling anaphylaxis in patients with systemic mastocytosis: a single-center experience.

scientific article published on 25 November 2011

Simultaneous Targeting of PARP1 and RAD52 Triggers Dual Synthetic Lethality in BRCA-Deficient Tumor Cells.

scientific article published in June 2018

Simvastatin reduces expression of cytokines interleukin-6, interleukin-8, and monocyte chemoattractant protein-1 in circulating monocytes from hypercholesterolemic patients.

scientific article

Simvastatin reduces the expression of adhesion molecules in circulating monocytes from hypercholesterolemic patients.

scientific article

Specific Activation of Human Mast Cells by the Ligand for c-Kit: Comparison between Lung, Uterus and Heart Mast Cells ⬇️

scientific article published on January 1, 1993

Spectrum of associated clonal hematologic non-mast cell lineage disorders occurring in patients with systemic mastocytosis.

scientific article

Splenic mastocytosis: report of two cases and detection of the transforming somatic C-KIT mutation D816V.

scientific article

Splenomegaly, elevated alkaline phosphatase and mutations in the SRSF2/ASXL1/RUNX1 gene panel are strong adverse prognostic markers in patients with systemic mastocytosis.

scientific article published on 15 July 2016

Stable non-transforming minimal residual disease in Philadelphia chromosome positive acute lymphoblastic leukemia after autologous transplantation: origin from neoplastic yet ‘pre-leukemic’ stem cells? ⬇️

scientific article published on April 4, 2011

Standard treatment of Ph+ CML in 2010: how, when and where not to use what BCR/ABL1 kinase inhibitor?

scientific article

Standardization of flow cytometry in myelodysplastic syndromes: a report from an international consortium and the European LeukemiaNet Working Group

scientific article published on 06 February 2012

Standards and Impact of Hematopathology in Myelodysplastic Syndromes (MDS) ⬇️

scientific article published on November 1, 2010

Stat5 tetramer formation is associated with leukemogenesis

scientific article published on 01 January 2005

Successful allogeneic hematopoietic stem cell transplantation for acute myeloid leukemia during respiratory failure and invasive mechanical ventilation.

scientific article

Successful treatment with arsenic trioxide of a patient with ATRA-resistant relapse of acute promyelocytic leukemia

scientific article published on 01 July 1999

Survival, prognostic factors and rates of leukemic transformation in 381 untreated patients with MDS and del(5q): a multicenter study.

scientific article published on 13 January 2012

Sustained remission including marked regression of a paravertebral plasmacytoma in a patient with heavily pretreated, relapsed multiple myeloma after treatment with bortezomib.

scientific article published on 16 June 2005

Symptomatic venous thromboembolism in acute leukemia. Incidence, risk factors, and impact on prognosis.

scientific article published in January 2005

Synergistic antiproliferative effects of KIT tyrosine kinase inhibitors on neoplastic canine mast cells.

scientific article published on 2 August 2007

Synergistic growth-inhibitory effects of two tyrosine kinase inhibitors, dasatinib and PKC412, on neoplastic mast cells expressing the D816V-mutated oncogenic variant of KIT.

scientific article published on November 2007

Systemic mastocytosis

scientific article published on 01 January 2008

Systemic mastocytosis (SM) associated with chronic eosinophilic leukemia (SM-CEL): detection of FIP1L1/PDGFRalpha, classification by WHO criteria, and response to therapy with imatinib.

scientific article published on 6 January 2006

Systemic mastocytosis associated with acute myeloid leukaemia: report of two cases and detection of the c-kit mutation Asp-816 to Val

scientific article published on 01 December 1998

Systemic mastocytosis associated with chronic idiopathic myelofibrosis: a distinct subtype of systemic mastocytosis associated with a [corrected] clonal hematological non-mast [corrected] cell lineage disorder carrying the activating point mutations

scientific article

Systems-pharmacology dissection of a drug synergy in imatinib-resistant CML.

scientific article

TKI rotation-induced persistent deep molecular response in multi-resistant blast crisis of Ph+ CML

scientific article

Target interaction profiling of midostaurin and its metabolites in neoplastic mast cells predicts distinct effects on activation and growth

scientific article

Targeting Nuclear NOTCH2 by Gliotoxin Recovers a Tumor-Suppressor NOTCH3 Activity in CLL

scientific article published on 18 June 2020

Targeting of Hsp32 in solid tumors and leukemias: a novel approach to optimize anticancer therapy.

scientific article

Targeting of VEGF-dependent transendothelial migration of cancer cells by bevacizumab.

scientific article

Targeting of heat-shock protein 32/heme oxygenase-1 in canine mastocytoma cells is associated with reduced growth and induction of apoptosis.

scientific article

Targeting of leukemia-initiating cells to develop curative drug therapies: straightforward but nontrivial concept.

scientific article published on January 2011

Targeting of mTOR is associated with decreased growth and decreased VEGF expression in acute myeloid leukaemia cells.

scientific article published in May 2009

Targeting the JAK2-STAT5 pathway in CML.

scientific article published on August 2014

The Austrian biodatabase for chronic myelomonocytic leukemia (ABCMML) : A representative and useful real-life data source for further biomedical research

scientific article published on 18 July 2019

The Btk tyrosine kinase is a major target of the Bcr-Abl inhibitor dasatinib

scholarly article

The Data Registry of the European Competence Network on Mastocytosis (ECNM): Set Up, Projects, and Perspectives

scientific article published on 08 November 2018

The European Competence Network on Mastocytosis (ECNM).

scientific article

The Hsp32 inhibitors SMA-ZnPP and PEG-ZnPP exert major growth-inhibitory effects on D34+/CD38+ and CD34+/CD38- AML progenitor cells

scientific article published on 01 January 2012

The IPSS-R has prognostic impact in untreated patients with MDS del(5q)

scientific article published on 23 July 2018

The IgE-reactive autoantigen Hom s 2 induces damage of respiratory epithelial cells and keratinocytes via induction of IFN-gamma.

scientific article published on 13 December 2007

The Italian Mastocytosis Registry: 6-year experience from a hospital-based registry

scientific article published on 12 September 2018

The JAK2 blocker TG101209 is a potent inhibitor of clonogenic progenitor cell growth in patients with chronic myeloid leukaemia

scientific article published on 21 February 2017

The JAK2/STAT5 signaling pathway as a potential therapeutic target in canine mastocytoma.

scientific article

The KIT and PDGFRA switch-control inhibitor DCC-2618 blocks growth and survival of multiple neoplastic cell types in advanced mastocytosis.

scientific article published on 8 February 2018

The Mastocytosis Society Survey on Mast Cell Disorders: Part 2-Patient Clinical Experiences and Beyond

scientific article published on 08 August 2018

The Mastocytosis Society survey on mast cell disorders: patient experiences and perceptions

scientific article published on 3 December 2013

The PI3 kinase/mTOR blocker NVP-BEZ235 overrides resistance against irreversible ErbB inhibitors in breast cancer cells.

scientific article published on 3 November 2010

The basophil activation marker defined by antibody 97A6 is identical to the ectonucleotide pyrophosphatase/phosphodiesterase 3

scientific article (publication date: 15 May 2001)

The basophil-specific ectoenzyme E-NPP3 (CD203c) as a marker for cell activation and allergy diagnosis

scientific article

The chemokine interleukin-8 and the surface activation protein CD69 are markers for Bcr-Abl activity in chronic myeloid leukemia.

scientific article published on 23 July 2008

The complement component C5a induces the expression of plasminogen activator inhibitor-1 in human macrophages via NF-kappaB activation.

scientific article

The growth and differentiation of mast cells ⬇️

scientific article published on January 1, 1991

The immunoglobulin E-allergen interaction: a target for therapy of type I allergic diseases.

scientific article published in July 1998

The impact of molecular targets in cancer drug development: major hurdles and future strategies.

scientific article

The mast cell as site of tissue-type plasminogen activator expression and fibrinolysis.

scientific article published on January 1999

The pan-BCL-2-blocker obatoclax (GX15-070) and the PI3-kinase/mTOR-inhibitor BEZ235 produce cooperative growth-inhibitory effects in ALL cells.

scientific article published on 28 June 2017

The phenotype of human eosinophils, basophils, and mast cells.

scientific article published in December 1994

The riddle of the mast cell: kit(CD117)-ligand as the missing link?

scientific article

The role of epigenetics in the regulation of apoptosis in myelodysplastic syndromes and acute myeloid leukemia.

scientific article published on 12 October 2013

The serum tryptase test: an emerging robust biomarker in clinical hematology.

scientific article

The surface membrane antigen phenotype of human blood basophils.

scientific article published in December 1994

The transcription factor MAZR preferentially acts as a transcriptional repressor in mast cells and plays a minor role in the regulation of effector functions in response to FcεRI stimulation.

scientific article

The tryptase positive compact round cell infiltrate of the bone marrow (TROCI-BM): a novel histopathological finding requiring the application of lineage specific markers

scientific article published on March 2006

The underestimated role of basophils in Ph chronic myeloid leukaemia

Therapeutic Vulnerabilities in -Mutant AML Unmasked by Palbociclib

scientific article published on 11 December 2018

Transcriptional plasticity promotes primary and acquired resistance to BET inhibition

scientific article published on 14 September 2015

Transjugular intrahepatic portosystemic shunt for treatment of portal hypertension due to extramedullary hematopoiesis in idiopathic myelofibrosis

scientific article published on 01 June 2002

Transposon-mediated generation of BCR-ABL1-expressing transgenic cell lines for unbiased sensitivity testing of tyrosine kinase inhibitors

scientific article published on 27 October 2016

Treatment concepts for elderly patients with acute myeloid leukemia.

scientific article

Treatment responses to cladribine and dasatinib in rapidly progressing aggressive mastocytosis.

scientific article published in November 2008

Trimolecular complex formation of IgE, Fc epsilon RI, and a recombinant nonanaphylactic single-chain antibody fragment with high affinity for IgE.

scientific article

Tumor stem cell research - basis and challenge for diagnosis and therapy

scientific article published on 22 July 2010

Twins with different personalities: STAT5B—but not STAT5A—has a key role in BCR/ABL-induced leukemia

scientific article published on 24 January 2019

Tyrosine kinase inhibitor-induced defects in DNA repair sensitize FLT3(ITD)-positive leukemia cells to PARP1 inhibitors.

scientific article

Unique effects of KIT D816V in BaF3 cells: induction of cluster formation, histamine synthesis, and early mast cell differentiation antigens.

scientific article

Up-regulation of LDL-receptor expression by LDL-immunoapheresis in patients with familial hypercholesterolemia

scientific article published on 01 September 1999

Update on genetic and molecular markers associated with myelodysplastic syndromes.

scientific article published on March 2009

Urticaria pigmentosa and mastocytosis: the role of immunophenotyping in diagnosis and determining response to treatment.

scientific article published on July 2006

Use of interleukin-11 to stimulate platelet production in myelodysplastic syndromes.

scientific article

Vaccination with genetically engineered allergens prevents progression of allergic disease.

scholarly article

Vaccination with genetically modified birch pollen allergens: Immune and clinical effects on oral allergy syndrome

scientific article published on 09 February 2007

Validation of WHO classification-based Prognostic Scoring System (WPSS) for myelodysplastic syndromes and comparison with the revised International Prognostic Scoring System (IPSS-R). A study of the International Working Group for Prognosis in Myelo

scientific article

Variability of PD-L1 expression in mastocytosis

scientific article published on 01 February 2018

Vascular safety issues in CML patients treated with BCR/ABL1 kinase inhibitors.

scientific article published on 18 December 2014

Vasoactive intestinal peptide receptor scintigraphy

scientific article published on 01 October 1995

Vasoactive intestinal peptide-receptor imaging for the localization of intestinal adenocarcinomas and endocrine tumors

scientific article published on 01 October 1994

What Have Mast Cells To Do with Edema Formation, the Consecutive Repair and Fibrinolysis? ⬇️

scientific article published on January 1, 1998

Why the 20% + 2 Tryptase Formula Is a Diagnostic Gold Standard for Severe Systemic Mast Cell Activation and Mast Cell Activation Syndrome

scientific article published on 28 June 2019

[Mastocytosis and eosinophilic leukemia: diagnostics and classification]

scientific article published on 01 November 2012

cFinder: definition and quantification of multiple haplotypes in a mixed sample

scientific article published on 7 September 2015

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