List of works - Antonio Leonardi

ABIN-1 binds to NEMO/IKKgamma and co-operates with A20 in inhibiting NF-kappaB

scientific article

APE1/Ref-1 interacts with NPM1 within nucleoli and plays a role in the rRNA quality control process.

scientific article

Analysis of the conformation and stability of rat TTF-1 homeodomain by circular dichroism

scientific article published on 01 November 1994

BIPHASIC CONTROL OF NF-κB ACTIVATION INDUCED BY THE TRIGGERING OF HLA-DR ANTIGENS EXPRESSED ON B CELLS

scientific article published on 01 May 1997

CIKS/DDX3X interaction controls the stability of the Zc3h12a mRNA induced by IL-17

scientific article

COMMD7 as a novel NEMO interacting protein involved in the termination of NF-κB signaling

scientific article published on 8 June 2015

Calcium interaction with bovine thyroglobulin: stoichiometry and structural consequences of calcium binding

scientific article published on 01 December 1991

Cancer-Selective Targeting of the NF-κB Survival Pathway with GADD45β/MKK7 Inhibitors

scientific article published on 8 December 2014

Cancer-selective targeting of the NF-κB survival pathway with GADD45β/MKK7 inhibitors

scientific article

Central role of the scaffold protein tumor necrosis factor receptor-associated factor 2 in regulating endoplasmic reticulum stress-induced apoptosis

scientific article published on 18 November 2005

Clinical proof of concept for a safe and effective NF-κB-targeting strategy in multiple myeloma

scientific article published on 26 September 2018

Cyclic AMP modulates the functional plasticity of immature dendritic cells by inhibiting Src-like kinases through protein kinase A-mediated signaling.

scientific article

Cytokine expression and ultrastructural alterations in fresh-frozen, freeze-dried and γ-irradiated human amniotic membranes

scientific article published on 12 April 2016

Diatom-derived oxylipins induce cell death in sea urchin embryos activating caspase-8 and caspase 3/7.

scientific article published on 22 April 2016

Down-regulation of wild-type p53-induced phosphatase 1 (Wip1) plays a critical role in regulating several p53-dependent functions in premature senescent tumor cells.

scientific article published on 23 April 2013

Effect of p53 activity on the sensitivity of human glioblastoma cells to PARP-1 inhibitor in combination with topoisomerase I inhibitor or radiation

scientific article published on 2 September 2014

Effects of a novel Nodal-targeting monoclonal antibody in melanoma

scientific article published on 9 October 2015

Endoplasmic reticulum stress causes thyroglobulin retention in this organelle and triggers activation of nuclear factor-kappa B via tumor necrosis factor receptor-associated factor 2.

scientific article published in June 2002

Expression of functional tissue factor in activated T-lymphocytes in vitro and in vivo: A possible contribution of immunity to thrombosis?

scientific article published on 3 May 2016

Folding of thyroglobulin in the calnexin/calreticulin pathway and its alteration by loss of Ca2+ from the endoplasmic reticulum

scientific journal article

Fructose induces prothrombotic phenotype in human endothelial cells : A new role for "added sugar" in cardio-metabolic risk

scientific article published on 24 June 2015

Generation and Characterization of Monoclonal Antibodies against a Cyclic Variant of Hepatitis C Virus E2 Epitope 412-422.

scientific article published on 27 January 2016

Human urotensin II induces tissue factor and cellular adhesion molecules expression in human coronary endothelial cells: an emerging role for urotensin II in cardiovascular disease.

scientific article published on 12 February 2008

Hypomorphic NOTCH3 mutation in an Italian family with CADASIL features

article

Mice deficient in nuclear factor (NF)-kappa B/p52 present with defects in humoral responses, germinal center reactions, and splenic microarchitecture

scientific article published in January 1998

NF-kappaB in solid tumors.

scientific article published on 7 September 2006

NF-κB Essential Modulator (NEMO) Is Critical for Thyroid Function.

scientific article published on 19 January 2016

NF-κB Mediates the Expression of TBX15 in Cancer Cells.

scientific article

NF-κB-dependent cytokine secretion controls Fas expression on chemotherapy-induced premature senescent tumor cells ⬇️

scientific article published on January 31, 2011

NGAL controls the metastatic potential of anaplastic thyroid carcinoma cells.

scientific article

New Anti-Nodal Monoclonal Antibodies Targeting the Nodal Pre-Helix Loop Involved in Cripto-1 Binding

scientific article

Novel STAT1 gain-of-function mutation and suppurative infections.

scientific article

Novel toll-like receptor 9 agonist induces epidermal growth factor receptor (EGFR) inhibition and synergistic antitumor activity with EGFR inhibitors.

scientific article published in January 2006

Physical and functional interaction of CARMA1 and CARMA3 with Ikappa kinase gamma-NFkappaB essential modulator

scientific article

Pregnancy-associated plasma protein-A promotes TF procoagulant activity in human endothelial cells by Akt-NF-κB axis.

scientific article

Presence of dityrosine bridges in thyroglobulin and their relationship with iodination.

scientific article published on July 1994

Promoter identification of CIKS, a novel NF-kappaB activating gene, and regulation of its expression

scientific article published on March 2003

Protection against Pseudomonas aeruginosa lung infection in mice by recombinant OprF-pulsed dendritic cell immunization

scientific article

Role of NF-kappaB in thyroid cancer.

scientific article published on 30 October 2009

Specific inhibition of the redox activity of ape1/ref-1 by e3330 blocks tnf-α-induced activation of IL-8 production in liver cancer cell lines

scientific article

TNF receptor-associated factor 1 is a positive regulator of the NF-kappaB alternative pathway

scientific article

TRAF2 and p38 are involved in B cells CD40-mediated APE/Ref-1 nuclear translocation: a novel pathway in B cell activation

scientific article published on 27 June 2007

TUCAN/CARDINAL and DRAL participate in a common pathway for modulation of NF-kappaB activation.

scientific article

Targeted next-generation sequencing revealed MYD88 deficiency in a child with chronic yersiniosis and granulomatous lymphadenitis

scientific article published on 26 November 2015

The adipokine apelin-13 induces expression of prothrombotic tissue factor.

scientific article

The adipokine visfatin induces tissue factor expression in human coronary artery endothelial cells: another piece in the adipokines puzzle

scientific article

Tumor necrosis factor (TNF) receptor-associated factor 7 is required for TNFα-induced Jun NH2-terminal kinase activation and promotes cell death by regulating polyubiquitination and lysosomal degradation of c-FLIP protein.

scientific article published on 3 January 2012

List of works by Antonio Leonardi

ABIN-1 binds to NEMO/IKKgamma and co-operates with A20 in inhibiting NF-kappaB

APE1/Ref-1 interacts with NPM1 within nucleoli and plays a role in the rRNA quality control process.

Analysis of the conformation and stability of rat TTF-1 homeodomain by circular dichroism

BIPHASIC CONTROL OF NF-κB ACTIVATION INDUCED BY THE TRIGGERING OF HLA-DR ANTIGENS EXPRESSED ON B CELLS

CIKS/DDX3X interaction controls the stability of the Zc3h12a mRNA induced by IL-17

COMMD7 as a novel NEMO interacting protein involved in the termination of NF-κB signaling

Calcium interaction with bovine thyroglobulin: stoichiometry and structural consequences of calcium binding

Cancer-Selective Targeting of the NF-κB Survival Pathway with GADD45β/MKK7 Inhibitors

Cancer-selective targeting of the NF-κB survival pathway with GADD45β/MKK7 inhibitors

Central role of the scaffold protein tumor necrosis factor receptor-associated factor 2 in regulating endoplasmic reticulum stress-induced apoptosis

Clinical proof of concept for a safe and effective NF-κB-targeting strategy in multiple myeloma

Cyclic AMP modulates the functional plasticity of immature dendritic cells by inhibiting Src-like kinases through protein kinase A-mediated signaling.

Cytokine expression and ultrastructural alterations in fresh-frozen, freeze-dried and γ-irradiated human amniotic membranes

Diatom-derived oxylipins induce cell death in sea urchin embryos activating caspase-8 and caspase 3/7.

Down-regulation of wild-type p53-induced phosphatase 1 (Wip1) plays a critical role in regulating several p53-dependent functions in premature senescent tumor cells.

Effect of p53 activity on the sensitivity of human glioblastoma cells to PARP-1 inhibitor in combination with topoisomerase I inhibitor or radiation

Effects of a novel Nodal-targeting monoclonal antibody in melanoma

Endoplasmic reticulum stress causes thyroglobulin retention in this organelle and triggers activation of nuclear factor-kappa B via tumor necrosis factor receptor-associated factor 2.

Expression of functional tissue factor in activated T-lymphocytes in vitro and in vivo: A possible contribution of immunity to thrombosis?

Folding of thyroglobulin in the calnexin/calreticulin pathway and its alteration by loss of Ca2+ from the endoplasmic reticulum

Fructose induces prothrombotic phenotype in human endothelial cells : A new role for "added sugar" in cardio-metabolic risk

Generation and Characterization of Monoclonal Antibodies against a Cyclic Variant of Hepatitis C Virus E2 Epitope 412-422.

Human urotensin II induces tissue factor and cellular adhesion molecules expression in human coronary endothelial cells: an emerging role for urotensin II in cardiovascular disease.

Hypomorphic NOTCH3 mutation in an Italian family with CADASIL features

Mice deficient in nuclear factor (NF)-kappa B/p52 present with defects in humoral responses, germinal center reactions, and splenic microarchitecture

NF-kappaB in solid tumors.

NF-κB Essential Modulator (NEMO) Is Critical for Thyroid Function.

NF-κB Mediates the Expression of TBX15 in Cancer Cells.

NF-κB-dependent cytokine secretion controls Fas expression on chemotherapy-induced premature senescent tumor cells ⬇️

NGAL controls the metastatic potential of anaplastic thyroid carcinoma cells.

New Anti-Nodal Monoclonal Antibodies Targeting the Nodal Pre-Helix Loop Involved in Cripto-1 Binding

Novel STAT1 gain-of-function mutation and suppurative infections.

Novel toll-like receptor 9 agonist induces epidermal growth factor receptor (EGFR) inhibition and synergistic antitumor activity with EGFR inhibitors.

Physical and functional interaction of CARMA1 and CARMA3 with Ikappa kinase gamma-NFkappaB essential modulator

Pregnancy-associated plasma protein-A promotes TF procoagulant activity in human endothelial cells by Akt-NF-κB axis.

Presence of dityrosine bridges in thyroglobulin and their relationship with iodination.

Promoter identification of CIKS, a novel NF-kappaB activating gene, and regulation of its expression

Protection against Pseudomonas aeruginosa lung infection in mice by recombinant OprF-pulsed dendritic cell immunization

Role of NF-kappaB in thyroid cancer.

Specific inhibition of the redox activity of ape1/ref-1 by e3330 blocks tnf-α-induced activation of IL-8 production in liver cancer cell lines

TNF receptor-associated factor 1 is a positive regulator of the NF-kappaB alternative pathway

TRAF2 and p38 are involved in B cells CD40-mediated APE/Ref-1 nuclear translocation: a novel pathway in B cell activation

TUCAN/CARDINAL and DRAL participate in a common pathway for modulation of NF-kappaB activation.

Targeted next-generation sequencing revealed MYD88 deficiency in a child with chronic yersiniosis and granulomatous lymphadenitis

The adipokine apelin-13 induces expression of prothrombotic tissue factor.

The adipokine visfatin induces tissue factor expression in human coronary artery endothelial cells: another piece in the adipokines puzzle

Tumor necrosis factor (TNF) receptor-associated factor 7 is required for TNFα-induced Jun NH2-terminal kinase activation and promotes cell death by regulating polyubiquitination and lysosomal degradation of c-FLIP protein.