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List of works by Norelle L Daly

A Synthetic mirror image of kalata B1 reveals that cyclotide activity is independent of a protein receptor

scientific article

A Tarantula-Venom Peptide Antagonizes the TRPA1 Nociceptor Ion Channel by Binding to the S1–S4 Gating Domain

scientific article

A comparison of the self-association behavior of the plant cyclotides kalata B1 and kalata B2 via analytical ultracentrifugation.

scientific article published on 15 October 2003

A defined α-helix in the bifunctional O-glycosylated natriuretic peptide TcNPa from the venom of Tropidechis carinatus.

scientific article published on 3 March 2015

A new family of cystine knot peptides from the seeds of Momordica cochinchinensis.

scientific article

A novel conotoxin inhibitor of Kv1.6 channel and nAChR subtypes defines a new superfamily of conotoxins.

scientific article published in July 2006

Acyclic permutants of naturally occurring cyclic proteins. Characterization of cystine knot and beta-sheet formation in the macrocyclic polypeptide kalata B1.

scientific article published in June 2000

Alanine scanning mutagenesis of the prototypic cyclotide reveals a cluster of residues essential for bioactivity.

scientific article

Albumins and their processing machinery are hijacked for cyclic peptides in sunflower

scientific article published on 20 March 2011

Alpha-selenoconotoxins, a new class of potent alpha7 neuronal nicotinic receptor antagonists

scientific article published on 24 February 2006

An engineered cyclic peptide alleviates symptoms of inflammation in a murine model of inflammatory bowel disease

scientific article published on 4 May 2017

Atypical alpha-conotoxin LtIA from Conus litteratus targets a novel microsite of the alpha3beta2 nicotinic receptor

scientific article

Backbone Cyclization Turns a Venom Peptide into a Stable and Equipotent Ligand at Both Muscle and Neuronal Nicotinic Receptors

scientific article published on 16 October 2020

Beta-arrestin 2 is required for complement C1q expression in macrophages and constrains factor-independent survival

scientific article published on 26 September 2009

Bioactive cystine knot proteins ⬇️

scientific article published on February 27, 2011

Capped acyclic permutants of the circular protein kalata B1.

scientific article published in November 2004

Carcinogenic Parasite Secretes Growth Factor That Accelerates Wound Healing and Potentially Promotes Neoplasia

scientific article

Characterisation of a Novel A-Superfamily Conotoxin

scientific article published on 20 May 2020

Chemical synthesis and biosynthesis of the cyclotide family of circular proteins

scientific article

Chemical synthesis and structure of the prokineticin Bv8

scientific article

Conopressin-T from Conus tulipa reveals an antagonist switch in vasopressin-like peptides

scientific article published on 2 January 2008

Conotoxin Φ-MiXXVIIA from the Superfamily G2 Employs a Novel Cysteine Framework that Mimics Granulin and Displays Anti-Apoptotic Activity

scientific article published on 5 October 2017

Conserved structural and sequence elements implicated in the processing of gene-encoded circular proteins

scientific article

Cyclic MrIA: a stable and potent cyclic conotoxin with a novel topological fold that targets the norepinephrine transporter

scientific article published on 01 November 2006

Cyclic Peptides Arising by Evolutionary Parallelism via Asparaginyl-Endopeptidase-Mediated Biosynthesis

scientific article

Cyclic thrombospondin-1 mimetics: grafting of a thrombospondin sequence into circular disulfide-rich frameworks to inhibit endothelial cell migration

scientific article

Cyclization of conotoxins to improve their biopharmaceutical properties.

scientific article published on 10 December 2010

Cyclotides: a patent review

scientific article

Cyclotides: macrocyclic peptides with applications in drug design and agriculture

scientific article published on October 2009

Decoding the membrane activity of the cyclotide kalata B1: the importance of phosphatidylethanolamine phospholipids and lipid organization on hemolytic and anti-HIV activities

scientific article

Design and Therapeutic Applications of Cyclotides ⬇️

scientific article published on December 1, 2009

Design and synthesis of truncated EGF-A peptides that restore LDL-R recycling in the presence of PCSK9 in vitro

scientific article

Design of substrate-based BCR-ABL kinase inhibitors using the cyclotide scaffold

scientific article

Development of Novel Melanocortin Receptor Agonists Based on the Cyclic Peptide Framework of Sunflower Trypsin Inhibitor-1.

scientific article published on 31 March 2018

Development of a Potent Wound Healing Agent Based on the Liver Fluke Granulin Structural Fold.

scientific article

Differences in the average single molecule activities of E. coli beta-galactosidase: effect of source, enzyme molecule age and temperature of induction

scientific article published on August 2003

Discovery and characterization of a linear cyclotide from Viola odorata: implications for the processing of circular proteins

scientific article

Discovery and structures of the cyclotides: novel macrocyclic peptides from plants

article

Discovery of an unusual biosynthetic origin for circular proteins in legumes

scientific article

Discovery of cyclotides in the fabaceae plant family provides new insights into the cyclization, evolution, and distribution of circular proteins.

scientific article

Discovery, structure and biological activities of cyclotides.

scientific article published on 23 May 2009

Discovery, structure and biological activities of the cyclotides

scientific article

Dual-targeting anti-angiogenic cyclic peptides as potential drug leads for cancer therapy

scientific article published on 13 October 2016

Effects of arginine 10 to lysine substitution on ω-conotoxin CVIE and CVIF block of Cav2.2 channels.

scientific article

Effects of cyclization on stability, structure, and activity of α-conotoxin RgIA at the α9α10 nicotinic acetylcholine receptor and GABA(B) receptor

scientific article published on 15 September 2011

Efficient backbone cyclization of linear peptides by a recombinant asparaginyl endopeptidase

scientific article published on 18 December 2015

Engineering of an Anti-Inflammatory Peptide Based on the Disulfide-Rich Linaclotide Scaffold

scientific article published on 6 October 2018

Engineering of conotoxins for the treatment of pain

scientific article published on December 2011

Engineering pro-angiogenic peptides using stable, disulfide-rich cyclic scaffolds

scientific article published on 28 October 2011

Engineering stable peptide toxins by means of backbone cyclization: stabilization of the alpha-conotoxin MII.

scientific article

Exploring the therapeutic potential of jellyfish venom.

scientific article

Folding of Truncated Granulin Peptides

scientific article published on 06 August 2020

High-affinity cyclic peptide matriptase inhibitors

scientific article published on 2 April 2013

Holocyclotoxin-1, a cystine knot toxin from Ixodes holocyclus

scientific article

Identification and Characterization of a Peptide from the Stony Coral Heliofungia actiniformis

scientific article published on 09 November 2020

Identification and characterization of a new family of cell-penetrating peptides: cyclic cell-penetrating peptides

scientific article

Identifying the immunomodulatory components of helminths

scientific article

In vivo efficacy of anuran trypsin inhibitory peptides against staphylococcal skin infection and the impact of peptide cyclization

scientific article

Inhibition of neuronal nicotinic acetylcholine receptor subtypes by alpha-Conotoxin GID and analogues

scientific article

Isolation and characterization of cytotoxic cyclotides from Viola philippica.

scientific article published on 23 June 2011

Isolation and characterization of cytotoxic cyclotides from Viola tricolor

scientific article published on 16 May 2010

Isolation and characterization of novel cyclotides from Viola hederaceae: solution structure and anti-HIV activity of vhl-1, a leaf-specific expressed cyclotide.

scientific article published on 11 April 2005

Isolation and characterization of peptides from Momordica cochinchinensis seeds

scientific article

Isolation and characterization of α-conotoxin LsIA with potent activity at nicotinic acetylcholine receptors

scientific article published on 4 August 2013

Isolation of an orally active insecticidal toxin from the venom of an Australian tarantula

scientific article

Isolation, sequencing, and structure-activity relationships of cyclotides.

scientific article published on September 2010

Isolation, solution structure, and insecticidal activity of kalata B2, a circular protein with a twist: do Möbius strips exist in nature?

scientific article published in January 2005

Isolation, structure, and activity of GID, a novel alpha 4/7-conotoxin with an extended N-terminal sequence

scientific article

Kalata B8, a novel antiviral circular protein, exhibits conformational flexibility in the cystine knot motif

scientific article published on February 2006

Knots in rings. The circular knotted protein Momordica cochinchinensis trypsin inhibitor-II folds via a stable two-disulfide intermediate.

scientific article published on 23 January 2006

Lipid core peptide targeting the cathepsin D hemoglobinase of Schistosoma mansoni as a component of a schistosomiasis vaccine

scientific article

Microcin J25 has a threaded sidechain-to-backbone ring structure and not a head-to-tail cyclized backbone

scientific article

Molecular engineering of conotoxins: the importance of loop size to alpha-conotoxin structure and function

scientific article published in September 2008

NMR and protein structure in drug design: application to cyclotides and conotoxins

scientific article

NMR as a tool for elucidating the structures of circular and knotted proteins.

scientific article published on 25 January 2007

NMR of conotoxins: structural features and an analysis of chemical shifts of post-translationally modified amino acids.

scientific article published on July 2006

Novel inhibitor cystine knot peptides from Momordica charantia

scientific article published in 2013

Oxidative folding of the cystine knot motif in cyclotide proteins.

scientific article

Oxytocic plant cyclotides as templates for peptide G protein-coupled receptor ligand design

scientific article

Phosphatidylethanolamine binding is a conserved feature of cyclotide-membrane interactions

scientific article

Potential therapeutic applications of the cyclotides and related cystine knot mini-proteins

scientific article published on May 2007

Quantification of small cyclic disulfide‐rich peptides ⬇️

scientific article published on January 1, 2012

RegIIA: an α4/7-conotoxin from the venom of Conus regius that potently blocks α3β4 nAChRs.

scientific article published on 16 November 2011

Retrocyclin-2: a potent anti-HIV theta-defensin that forms a cyclic cystine ladder structural motif.

scientific article published in January 2009

Retrocyclin-2: structural analysis of a potent anti-HIV theta-defensin

scientific article

Revisiting Inflammatory Bowel Disease: Pathology, Treatments, Challenges and Emerging Therapeutics Including Drug Leads from Natural Products

scientific article published on 28 April 2020

Role of phosphorylation in the conformation of tau peptides implicated in Alzheimer's disease.

scientific article published in August 2000

STRUCTURE AND FUNCTION OF PLANT TOXINS (WITH EMPHASIS ON CYSTINE KNOT TOXINS)

article

Small Molecules in the Venom of the Scorpion Hormurus waigiensis

scientific article published on 31 July 2020

Solution Structure, Membrane Interactions, and Protein Binding Partners of the Tetraspanin Sm-TSP-2, a Vaccine Antigen from the Human Blood FlukeSchistosoma mansoni

scientific article

Solution structure and characterization of the LGR8 receptor binding surface of insulin-like peptide 3.

scientific article

Solution structure and novel insights into the determinants of the receptor specificity of human relaxin-3.

scientific article

Solution structure by NMR of circulin A: a macrocyclic knotted peptide having anti-HIV activity

scientific article

Solution structure of BSTI: a new trypsin inhibitor from skin secretions of Bombina bombina

scientific article

Solution structure of alpha-conotoxin ImI by 1H nuclear magnetic resonance

scientific article

Solution structure of chi-conopeptide MrIA, a modulator of the human norepinephrine transporter

scientific article

Solution structure of the cyclotide palicourein: implications for the development of a pharmaceutical framework

scientific article

Solution structure, aggregation behavior, and flexibility of human relaxin-2

scientific article

Solving the alpha-conotoxin folding problem: efficient selenium-directed on-resin generation of more potent and stable nicotinic acetylcholine receptor antagonists.

scientific article published in March 2010

Stabilization of α-Conotoxin AuIB: Influences of Disulfide Connectivity and Backbone Cyclization

scientific article published on 20 August 2010

Structural Insights into the Role of the Cyclic Backbone in a Squash Trypsin Inhibitor

scientific article

Structural Variants of a Liver Fluke Derived Granulin Peptide Potently Stimulate Wound Healing

scientific article published on 24 September 2018

Structural and biochemical characteristics of the cyclotide kalata B5 from Oldenlandia affinis

scientific article

Structural and functional characterization of the conserved salt bridge in mammalian paneth cell alpha-defensins: solution structures of mouse CRYPTDIN-4 and (E15D)-CRYPTDIN-4.

scientific article published on 20 July 2006

Structural diversity of arthropod venom toxins

scientific article published on 21 July 2018

Structural insights into the function of relaxins

scientific article

Structural plasticity of the cyclic-cystine-knot framework: implications for biological activity and drug design.

scientific article published in February 2006

Structural properties of relaxin chimeras.

scientific article

Structural studies of conotoxins

scientific article

Structure and Biological Activity of a Turripeptide from Unedogemmula bisaya Venom.

scientific article published in November 2017

Structure and activity of alpha-conotoxin PeIA at nicotinic acetylcholine receptor subtypes and GABA(B) receptor-coupled N-type calcium channels

scientific article

Structure of catalytic domain of Matriptase in complex with Sunflower trypsin inhibitor-1

scientific article

Structure of human insulin-like peptide 5 and characterization of conserved hydrogen bonds and electrostatic interactions within the relaxin framework

scientific article

Structure of the R3/I5 Chimeric Relaxin Peptide, a Selective GPCR135 and GPCR142 Agonist

scientific article

Structure of α-conotoxin BuIA: influences of disulfide connectivity on structural dynamics ⬇️

scientific article

Structures of muO-conotoxins from Conus marmoreus. I nhibitors of tetrodotoxin (TTX)-sensitive and TTX-resistant sodium channels in mammalian sensory neurons.

scientific article

Structures of naturally occurring circular proteins from bacteria

scientific article

Synthesis and structural analysis of the N-terminal domain of the thyroid hormone-binding protein transthyretin

scientific article

Synthesis, Pharmacological and Structural Characterization of Novel Conopressins from Conus miliaris

scientific article published on 06 March 2020

The A-chain of human relaxin family peptides has distinct roles in the binding and activation of the different relaxin family peptide receptors

scientific article published on 22 April 2008

The Aromatic Head Group of Spider Toxin Polyamines Influences Toxicity to Cancer Cells

scientific article published on 27 October 2017

The C-terminal propeptide of a plant defensin confers cytoprotective and subcellular targeting functions

scientific article published on 05 February 2014

The Cyclic Cystine Ladder in  -Defensins Is Important for Structure and Stability, but Not Antibacterial Activity

scientific article

The N-terminal pro-domain of the kalata B1 cyclotide precursor is intrinsically unstructured

scientific article published on 26 August 2016

The absolute structural requirement for a proline in the P3'-position of Bowman-Birk protease inhibitors is surmounted in the minimized SFTI-1 scaffold

scientific article published on 09 June 2006

The biological activity of the prototypic cyclotide kalata b1 is modulated by the formation of multimeric pores

scientific article

The cyclic cystine knot miniprotein MCoTI-II is internalized into cells by macropinocytosis.

scientific article published on 7 July 2007

The cyclotide family of circular miniproteins: nature's combinatorial peptide template.

scientific article

The cyclotide fingerprint in oldenlandia affinis: elucidation of chemically modified, linear and novel macrocyclic peptides

scientific article published on 01 June 2007

The cystine knot motif in toxins and implications for drug design.

scientific article

The discovery and development of a natural combinatorial peptide template: the cyclotides

scientific article published on 01 January 2009

The role of the cyclic peptide backbone in the anti-HIV activity of the cyclotide kalata B1

scientific article published on 01 September 2004

The self-association of the cyclotide kalata B2 in solution is guided by hydrophobic interactions.

scientific article published on September 2013

The three-dimensional structure of the analgesic alpha-conotoxin, RgIA.

scientific article

The α-defensin salt-bridge induces backbone stability to facilitate folding and confer proteolytic resistance

scientific article

Three-dimensional structure of a cysteine-rich repeat from the low-density lipoprotein receptor

scientific article

Three-dimensional structure of the second cysteine-rich repeat from the human low-density lipoprotein receptor

scientific article

Total Synthesis of the Analgesic Conotoxin MrVIB through Selenocysteine-Assisted Folding

article

Transforming conotoxins into cyclotides: Backbone cyclization of P-superfamily conotoxins

scientific article

Twists, knots, and rings in proteins. Structural definition of the cyclotide framework

scientific article

Venomics: A Mini-Review

article

Vicinal Disulfide Constrained Cyclic Peptidomimetics: a Turn Mimetic Scaffold Targeting the Norepinephrine Transporter

scientific article published on 24 September 2013

α-Conotoxin ImI Incorporating Stable Cystathionine Bridges Maintains Full Potency and Identical Three-Dimensional Structure

scientific article published on 15 September 2011

α-Conotoxin MrIC is a biased agonist at α7 nicotinic acetylcholine receptors.

scientific article

θ-Defensins Prevent HIV-1 Env-mediated Fusion by Binding gp41 and Blocking 6-Helix Bundle Formation

scientific article published in Journal of Biological Chemistry

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