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List of works by Tim R Blower

A complex suite of loci and elements in eukaryotic type II topoisomerases determine selective sensitivity to distinct poisoning agents

scientific article published on 01 September 2019

A nucleotidyltransferase toxin inhibits growth of Mycobacterium tuberculosis through inactivation of tRNA acceptor stems

scientific article published on 29 July 2020

A processed noncoding RNA regulates an altruistic bacterial antiviral system

scientific article

A promiscuous antitoxin of bacteriophage T4 ensures successful viral replication.

scientific article

A widespread family of WYL-domain transcriptional regulators co-localizes with diverse phage defence systems and islands

scientific article published on 01 May 2022

AbiEi Binds Cooperatively to the Type IV abiE Toxin-Antitoxin Operator Via a Positively-Charged Surface and Causes DNA Bending and Negative Autoregulation.

scientific article

Allophycocyanin A is a carbon dioxide receptor in the cyanobacterial phycobilisome

scientific article published in 2022

Anticancer RuII and RhIII Piano-Stool Complexes that are Histone Deacetylase Inhibitors

scientific article published on 12 October 2016

Anticancer Ruthenium Complexes with HDAC Isoform Selectivity

scientific article published on 21 May 2020

Balancing at survival's edge: the structure and adaptive benefits of prokaryotic toxin-antitoxin partners.

scientific article published on February 2011

Co-evolution of quaternary organization and novel RNA tertiary interactions revealed in the crystal structure of a bacterial protein-RNA toxin-antitoxin system.

scientific article published on 8 September 2015

Crystal structure and stability of gyrase-fluoroquinolone cleaved complexes from Mycobacterium tuberculosis.

scientific article published on 20 January 2016

DNA driven self-assembly of micron-sized rods using DNA-grafted bacteriophage fd virions

scientific article published on March 2015

Evolution of Pectobacterium Bacteriophage ΦM1 To Escape Two Bifunctional Type III Toxin-Antitoxin and Abortive Infection Systems through Mutations in a Single Viral Gene.

scientific article published on 3 February 2017

Fluoroquinolone interactions with Mycobacterium tuberculosis gyrase: Enhancing drug activity against wild-type and resistant gyrase

scientific article published on 20 January 2016

Identification and classification of bacterial Type III toxin-antitoxin systems encoded in chromosomal and plasmid genomes.

scientific article

Mechanism of Action of Mycobacterium tuberculosis Gyrase Inhibitors: A Novel Class of Gyrase Poisons

scientific article published on 17 May 2018

Mutagenesis and functional characterization of the RNA and protein components of the toxIN abortive infection and toxin-antitoxin locus of Erwinia

scientific article

Recognition of DNA Supercoil Geometry by Mycobacterium tuberculosis Gyrase.

scientific article published on 18 September 2017

The phage abortive infection system, ToxIN, functions as a protein-RNA toxin-antitoxin pair

scientific article

The phage defence island of a multidrug resistant plasmid uses both BREX and type IV restriction for complementary protection from viruses

scientific article published on 01 November 2021

Viral evasion of a bacterial suicide system by RNA-based molecular mimicry enables infectious altruism.

scientific article