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List of works by Christine Chomienne

1 alpha,25-dihydroxyvitamin D3 transrepresses retinoic acid transcriptional activity via vitamin D receptor in myeloid cells

scientific article

1-B-D arabinofuranosyl cytosine and all-trans retinoic acid in combination accelerates and increases monocyte differentiation of myeloid leukemic cells

scientific article published on 01 January 1986

A PML/retinoic acid receptor alpha fusion transcript is constantly detected by RNA-based polymerase chain reaction in acute promyelocytic leukemia ⬇️

scientific article published on June 15, 1992

A RP-UFLC Assay for Protein Tyrosine Phosphatases: Focus on Protein Tyrosine Phosphatase Non-Receptor Type 2 (PTPN2).

scientific article published on 4 June 2015

A new variant t(6;15;17)(q25;q22;q21) in acute promyelocytic leukemia: fluorescence in situ hybridization confirmation.

scientific article published on May 2005

A prospective study of bone marrow hematopoietic and mesenchymal stem cells in type 1 Gaucher disease patients

scientific article

A randomized comparison of all transretinoic acid (ATRA) followed by chemotherapy and ATRA plus chemotherapy and the role of maintenance therapy in newly diagnosed acute promyelocytic leukemia. The European APL Group

scientific article (publication date: 15 August 1999)

AK2 deficiency compromises the mitochondrial energy metabolism required for differentiation of human neutrophil and lymphoid lineages

scientific article

Acute promyelocytic leukemia: a model ofpersonalized medicine.

scientific article

Additional chromosomal abnormalities in patients with acute promyelocytic leukaemia (APL) do not confer poor prognosis: results of APL 93 trial

Age and aging in blood disorders: EHA theme of the year 2013-2014.

scientific article published in June 2013

All trans retinoic acid in acute promyelocytic leukemia

scientific article published on 01 January 1991

All trans retinoic acid treatment for patients with acute promyelocytic leukemia.

scientific article published in January 1992

All-trans retinoic acid as a differentiation therapy for acute promyelocytic leukemia. I. Clinical results

scientific article

All-trans retinoic acid in acute promyelocytic leukemias. II. In vitro studies: structure-function relationship.

scientific article

All-trans retinoic acid in adult chronic myelomonocytic leukemia: results of a pilot study.

scientific article

All-trans retinoic acid in relapsing malignant gliomas: clinical and radiological stabilization associated with the appearance of intratumoral calcifications.

scientific article published in September 1997

All-trans retinoic acid pharmacokinetics and bioavailability in acute promyelocytic leukemia: intracellular concentrations and biologic response relationship.

scientific article published in October 1995

All-trans-retinoic acid as a differentiating agent in the treatment of acute promyelocytic leukemia.

scientific article published on May 1995

All-trans-retinoic acid enhances apoptosis induction by tyrosine kinase inhibitors in the eosinophilic leukemia-derived EoL-1 cell line.

scientific article

Alteration of the PML proto-oncogene in leukemic cells does not abrogate expression of MHC class I antigens

scientific article published on 01 August 1999

Alterations of the retinoic acid receptor alpha (RAR alpha) gene in myeloid and lymphoid malignancies.

scientific article published in March 1999

Amino-terminal protein-protein interaction motif (POZ-domain) is responsible for activities of the promyelocytic leukemia zinc finger-retinoic acid receptor-alpha fusion protein

scientific article

An analysis of prognostic factors in preleukemia: interest of bone marrow scintigraphy

scientific article published on 01 April 1984

Analysis of the ten-eleven translocation 2 (TET2) gene in familial myeloproliferative neoplasms

scientific article published on 29 June 2009

Aplastic crisis and erythema infectiosum (fifth disease) revealing a hereditary spherocytosis in a familial human parvovirus infection

scientific article published on 01 January 1986

Apoptosis induction by retinoids in eosinophilic leukemia cells: implication of retinoic acid receptor-alpha signaling in all-trans-retinoic acid hypersensitivity.

scientific article published on June 2006

Arsenic Trioxide Enhances the NK Cell Cytotoxicity Against Acute Promyelocytic Leukemia While Simultaneously Inhibiting Its Bio-Genesis.

scientific article published on 14 June 2018

Assessing Bone Marrow Activity in Patients with Myelofibrosis: Results of a Pilot Study of 18F-FLT PET.

scientific article published on 30 March 2017

Auer rods and differentiation in acute promyelocytic leukemia

BCL-2 and Mutant NRAS Interact Physically and Functionally in a Mouse Model of Progressive Myelodysplasia

scientific article published on 01 December 2007

BCL-2 inhibition with ABT-737 prolongs survival in an NRAS/BCL-2 mouse model of AML by targeting primitive LSK and progenitor cells

scientific article published on 13 August 2013

BCL2L10 positive cells in bone marrow are an independent prognostic factor of azacitidine outcome in myelodysplastic syndrome and acute myeloid leukemia

scientific article published on 27 April 2017

Bexarotene via CBP/p300 induces suppression of NF-κB-dependent cell growth and invasion in thyroid cancer

scientific article

Biological features of primary APL blasts: their relevance to the understanding of granulopoiesis, leukemogenesis and patient management ⬇️

scientific article published on October 29, 2001

Biology and treatment of acute promyelocytic leukemia.

scientific article published on January 1996

Blood disorders stepping into the limelight

scientific article published on 27 January 2016

Bone marrow microenvironment in an in vitro model of Gaucher disease: consequences of glucocerebrosidase deficiency.

scientific article published on 18 October 2011

Bone marrow microenvironment in fanconi anemia: a prospective functional study in a cohort of fanconi anemia patients

scientific article published on 01 February 2010

CD11c gene expression in hairy cell leukemia is dependent upon activation of the proto-oncogenes ras and junD.

scientific article published on 6 February 2003

CD44 activation enhances acute monoblastic leukemia cell survival via Mcl-1 upregulation

scientific article published on 11 October 2011

CD44 targeting reduces tumour growth and prevents post-chemotherapy relapse of human breast cancers xenografts.

scientific article published on 24 February 2009

CD44-ligation induces, through ERK1/2 pathway, synthesis of cytokines TNF-alpha and IL-6 required for differentiation of THP-1 monoblastic leukemia cells

scientific article published on 27 May 2010

Cancer stem cell definitions and terminology: the devil is in the details

scientific article published on 11 October 2012

Changes in microrheology of acute promyelocytic leukemia cells during all-trans retinoic acid (ATRA) differentiation therapy: a mechanism for ATRA-induced hyperleukocytosis?

scientific article published on September 1995

Characterization of nuclear retinoic acid binding activity in sensitive leukemic cell lines: cell specific uptake of ATRA and RAR alpha protein modulation.

scientific article published on August 1995

Classification of myeloproliferative disorders in the JAK2 era: is there a role for red cell mass?

scientific article published on 23 August 2007

Clinical and molecular characterization of a rare syndrome of acute promyelocytic leukemia associated with translocation (11;17).

scientific article published on February 1995

Clinical and molecular response to interferon-α therapy in essential thrombocythemia patients with CALR mutations.

scientific article

Coexistence of a myeloproliferative disorder and secondary polycythemia in the same patient

scientific article published on 31 March 2012

Combined treatment with arsenic trioxide and all-trans-retinoic acid in patients with relapsed acute promyelocytic leukemia

scientific article published in June 2003

Comparison of human skeletal myoblasts and bone marrow-derived CD133+progenitors for the repair of infarcted myocardium

scientific article published on 01 July 2004

Comparison of newly diagnosed and relapsed patients with acute promyelocytic leukemia treated with arsenic trioxide: insight into mechanisms of resistance

scientific article

Contribution of GM-CSF and IL-8 to the CD44-induced differentiation of acute monoblastic leukemia

scientific article published on 04 October 2007

Cooperative action of 1alpha,25-dihydroxyvitamin D3 and retinoic acid in NB4 acute promyelocytic leukemia cell differentiation is transcriptionally controlled.

scientific article published on 21 September 2005

Correction for Cassinat et al., "New Role for Granulocyte Colony-Stimulating Factor-Induced Extracellular Signal-Regulated Kinase 1/2 in Histone Modification and Retinoic Acid Receptor α Recruitment to Gene Promoters: Relevance to Acute Promyelocyti

scientific article published on 29 June 2017

Costs of haematological disease high and rising.

scientific article published on 22 July 2016

Current data on GM-CSF (Granulocyte-Macrophage Colony Stimulating Factor) in acute myeloid leukemia

scientific article published on January 1, 1992

DNA topoisomerase II in therapy-related acute promyelocytic leukemia.

scientific article published in April 2005

DNA vaccination with all-trans retinoic acid treatment induces long-term survival and elicits specific immune responses requiring CD4+ and CD8+ T-cell activation in an acute promyelocytic leukemia mouse model

scientific article published on 19 November 2009

DNA-mediated adjuvant immunotherapy extends survival in two different mouse models of myeloid malignancies

scientific article published on 10 September 2015

Diagnostic value of bone marrow imaging with 111indium-transferrin and 99m technetium-colloids in myelofibrosis

scientific article published on 01 March 1985

Differential expression of c-myc and c-fos oncogenes during the differentiation of human leukemic cells by Ara-C

scientific article published on 01 April 1987

Differential uptake of all-trans retinoic acid by acute promyelocytic leukemic cells: evidence for its role in retinoic acid efficacy

scientific article published on 01 January 1995

Differentiation or death: the view from Versailles.

scientific article published in August 1998

Discrepancy between in vitro and in vivo passaged U-937 human leukemic cells: tumorigenicity and sensitivity to differentiating drugs

scientific article published on 01 May 1988

Distinct sensitivity of neuroblastoma cells for retinoid receptor agonists: evidence for functional receptor heterodimers

scientific article published on 01 October 1997

Does increasing the JAK2V617F assay sensitivity allow to identify more patients with MPN?

scientific article published on 4 May 2012

Early onset of chemotherapy can reduce the incidence of ATRA syndrome in newly diagnosed acute promyelocytic leukemia (APL) with low white blood cell counts: results from APL 93 trial

scientific article published on 01 February 2003

Effect of 5-aza-2′-deoxycytidine and vitamin D 3 analogs on growth and differentiation of human myeloid leukemic cells ⬇️

scientific article published on January 1, 1998

Effectiveness and pharmacokinetics of low-dose all-trans retinoic acid (25 mg/m2) in acute promyelocytic leukemia

scientific article published on 01 December 1993

Effects of anti-CD44 monoclonal antibodies on differentiation and apoptosis of human myeloid leukemia cell lines ⬇️

scientific article published on January 1, 2002

Endoplasmic reticulum calcium transport ATPase expression during differentiation of colon cancer and leukaemia cells.

scientific article published in October 2004

Engineering mouse models with myelodysplastic syndrome human candidate genes; how relevant are they?

scientific article

Enhanced calreticulin expression in red cells of polycythemia vera patients harboring the JAK2V617F mutation.

scientific article published on 6 April 2017

Epstein-Barr virus latent membrane protein 1 increases calcium influx through store-operated channels in B lymphoid cells.

scientific article

Erosion of the chronic myeloid leukaemia stem cell pool by PPARγ agonists

scientific article

Essential thrombocythemias without V617F JAK2 mutation are clonal hematopoietic stem cell disorders

scientific article published on 01 June 2006

Establishing optimal quantitative-polymerase chain reaction assays for routine diagnosis and tracking of minimal residual disease in JAK2-V617F-associated myeloproliferative neoplasms: a joint European LeukemiaNet/MPN&MPNr-EuroNet (COST action BM090

scientific article published on 17 July 2013

Evaluation of a new thyroglobulin sensitive assay in patients with differentiated thyroid cancer.

scientific article published in February 2015

Evolving characteristics and outcome of secondary acute promyelocytic leukemia (APL): A prospective analysis by the French-Belgian-Swiss APL group

scientific article

Extramedullary relapse in acute promyelocytic leukemia treated with all-trans retinoic acid and chemotherapy.

scientific article published in January 2006

Fanconi's anaemia associated with multicentric Bowen's disease and decreased NK cytotoxicity

scientific article published on 01 November 1993

Farnesyltransferase inhibitor tipifarnib (R115777) preferentially inhibits in vitro autonomous erythropoiesis of polycythemia vera patient cells.

scientific article published on 4 January 2005

Favourable outcome in an APL patient with PLZF/RARalpha fusion gene: quantitative real-time RT-PCR confirms molecular response.

scientific article

Feasibility of high-throughput sequencing in clinical routine cancer care: lessons from the cancer pilot project of the France Genomic Medicine 2025 plan

scientific article published on 01 July 2020

Flow cytometry comparison of CD34+ subsets in bone marrow and peripheral blood after priming with glycosylated or non-glycosylated rhG-CSF

scientific article published on 01 August 1999

Frequent antibody production against RARalpha in both APL mice and patients

scientific article published on 25 May 2006

From Noonan syndrome to juvenile myelomonocytic leukemia

scientific article published in June 2008

G-CSF activates STAT pathways in Kasumi-1 myeloid leukemic cells with the t(8; 21) translocation: basis for potential therapeutic efficacy

scientific article published on June 1, 1997

GEP analysis validates high risk MDS and acute myeloid leukemia post MDS mice models and highlights novel dysregulated pathways

scientific article published on 27 January 2016

Genetic typing of CBL, ASXL1, RUNX1, TET2 and JAK2 in juvenile myelomonocytic leukaemia reveals a genetic profile distinct from chronic myelomonocytic leukaemia

scientific article published on 19 October 2010

Germline mutations of the CBL gene define a new genetic syndrome with predisposition to juvenile myelomonocytic leukaemia.

scientific article published on 12 June 2010

Glucocerebrosidase deficiency dramatically impairs human bone marrow haematopoiesis in an in vitro model of Gaucher disease.

scientific article published on 9 May 2010

Granulocytic colony-stimulating factors (G-CSF and GM-CSF) in the treatment of adult acute myeloid leukemia

scientific article published on 01 January 1991

Granulocytic differentiation induced by retinoic acid in HL-60 cells is associated with changes in adenylate cyclase activity

scientific article published on 01 July 1986

Health, economic, and quality-of-life effects of erythropoietin and granulocyte colony-stimulating factor for the treatment of myelodysplastic syndromes: a randomized, controlled trial

scientific article published on 30 March 2004

Heterogeneity of neoplastic stem cells: theoretical, functional, and clinical implications.

scientific article published on 23 January 2013

High molecular response rate of polycythemia vera patients treated with pegylated interferon alpha-2a

scientific article

Histone deacetylase inhibitors (HDI) cause DNA damage in leukemia cells: a mechanism for leukemia-specific HDI-dependent apoptosis?

scientific article

Identification of JAK2 mutations in canine primary polycythemia.

scientific article

Impact of hydroxycarbamide and interferon-α on red cell adhesion and membrane protein expression in polycythemia vera.

scientific article published on 29 March 2018

In hematopoietic cells with a germline mutation of CBL, loss of heterozygosity is not a signature of juvenile myelo-monocytic leukemia.

scientific article published on 4 July 2013

In vitro all-trans retinoic acid (ATRA) sensitivity and cellular retinoic acid binding protein (CRABP) levels in relapse leukemic cells after remission induction by ATRA in acute promyelocytic leukemia.

scientific article

In vitro effects of retinoic acid

scientific article published on 01 January 1990

In vitro treatment with retinoids or the topoisomerase inhibitor, VP-16, evidences different functional apoptotic pathways in acute promyelocytic leukemic cells

scientific article published on 01 December 1995

Incidence, clinical features, and outcome of all trans-retinoic acid syndrome in 413 cases of newly diagnosed acute promyelocytic leukemia. The European APL Group.

scientific article published on October 1998

Induction of retinoic acid-binding protein in normal and malignant human myeloid cells by retinoic acid in acute promyelocytic leukemia patients

scientific article published on 01 June 1992

Induction of retinoid resistance by all-trans retinoic acid in acute promyelocytic leukemia after remission

scientific article published on July 1995

Induction of thrombospondin-1 by all-trans retinoic acid modulates growth and differentiation of HL-60 myeloid leukemia cells ⬇️

scientific article published on December 1, 1997

Induction treatment of acute promyelocytic leukemia using all-trans retinoic acid. Controversies about dosage, advantages and side-effect management

scientific article published on 01 January 1994

Inefficacy of the synthetic aromatic retinoid etretinate and of its free acid on the in-vitro differentiation of leukemic cells

scientific article published on 01 January 1986

Interferon-alpha therapy in bcr-abl-negative myeloproliferative neoplasms.

scientific article published on 09 October 2008

Interlaboratory development and validation of a HRM method applied to the detection of JAK2 exon 12 mutations in polycythemia vera patients

scientific article

Is Cytarabine Useful in the Treatment of Acute Promyelocytic Leukemia? Results of a Randomized Trial From the European Acute Promyelocytic Leukemia Group

article by Lionel Adès et al published 20 December 2006 in Journal of Clinical Oncology

Is the thrombopoietin assay useful for differential diagnosis of thrombocytopenia? Analysis of a cohort of 160 patients with thrombocytopenia and defined platelet life span.

scientific article

JAK2V617F activates Lu/BCAM-mediated red cell adhesion in polycythemia vera through an EpoR-independent Rap1/Akt pathway

scientific article

Juvenile chronic myelomonocytic leukemias: molecular and novel therapeutic basis.

scientific article published on September 1997

Juvenile myelomonocytic leukaemia and Noonan syndrome.

scientific article published on 5 August 2014

Juvenile myelomonocytic leukemia displays mutations in components of the RAS pathway and the PRC2 network.

scientific article published on 12 October 2015

Ligation of the CD44 adhesion molecule reverses blockage of differentiation in human acute myeloid leukemia

scientific article published on 01 June 1999

Lineage-specific modulation of calcium pump expression during myeloid differentiation.

scientific article published in June 1999

Lithium chloride antileukemic activity in acute promyelocytic leukemia is GSK-3 and MEK/ERK dependent.

scientific article published on 25 June 2015

Localization of the NRAS:BCL-2 complex determines anti-apoptotic features associated with progressive disease in myelodysplastic syndromes

scientific article published on 12 November 2012

Long-term follow-up of European APL 2000 trial, evaluating the role of cytarabine combined with ATRA and Daunorubicin in the treatment of nonelderly APL patients

scientific article

Long-term incidence of hematological evolution in three French prospective studies of hydroxyurea and pipobroman in polycythemia vera and essential thrombocythemia.

scientific article published on June 2006

Lu/BCAM-mediated cell adhesion as biological marker of JAK2V617F activity in erythrocytes of polycythemia vera patients.

scientific article

Mapping of the human CD11c (ITGAX) and CD11d (ITGAD) genes demonstrates that they are arranged in tandem separated by no more than 11.5 kb

scientific article

Mechanism of action of retinoids in a new therapeutic approach to acute promyelocytic leukemia

scientific article published on 01 January 1992

Midkine (MK), a retinoic acid (RA)-inducible gene product, produced in E. coli acts on neuronal and HL60 leukemia cells.

scientific article published in January 1993

Modulation of B-cell endoplasmic reticulum calcium homeostasis by Epstein-Barr virus latent membrane protein-1. ⬇️

scientific article

Modulation of endoplasmic reticulum calcium pump expression during lung cancer cell differentiation.

scientific article published on 11 December 2012

Mutations in exon 12 of JAK2 are mainly found in JAK2 V617F-negative polycythaemia vera patients.

scientific article published on 22 May 2008

Mutations in the ELA2 gene correlate with more severe expression of neutropenia: a study of 81 patients from the French Neutropenia Register.

scientific article published on 12 February 2004

New chimeric RNAs in acute myeloid leukemia

scientific article published on 2 August 2017

New role for granulocyte colony-stimulating factor-induced extracellular signal-regulated kinase 1/2 in histone modification and retinoic acid receptor α recruitment to gene promoters: relevance to acute promyelocytic leukemia cell differentiation.

scientific article

Occurrence of myelodysplastic syndrome in 2 patients with reticular dysgenesis

scientific article published on 31 March 2011

Oral 9-cis retinoic acid (Alitretinoin) in the treatment of myelodysplastic syndromes: results from a pilot study

scientific article published on 01 September 2000

Outcome of acute promyelocytic leukemia (APL) in children and adolescents: an analysis in two consecutive trials of the European APL Group.

scientific article published on 2 April 2012

Outcome of acute promyelocytic leukemia treated with all trans retinoic acid and chemotherapy in elderly patients: the European group experience.

scientific article published in February 2005

Outcome of childhood acute promyelocytic leukemia with all-trans-retinoic acid and chemotherapy.

scientific article published in April 2004

PML-RARA-targeted DNA vaccine induces protective immunity in a mouse model of leukemia.

scientific article published on 19 October 2003

PML-RARalpha ligand-binding domain deletion mutations associated with reduced disease control and outcome after first relapse of APL

scientific article published on 29 October 2009

PML/RAR alpha rearrangement in acute promyelocytic leukaemia with t(1;17) elucidated using fluorescence in situ hybridization

scientific article published on 01 August 1997

Partial restoration of all trans retinoic acid (ATRA) sensitivity by compactin in ATRA-resistant leukemic cells (ATRA-R HL-60)

scientific article published on 01 June 2000

Pegylated interferon-alfa-2a induces complete hematologic and molecular responses with low toxicity in polycythemia vera

article

Pharmacokinetic data on very-low-dose cytarabine

scientific article published on 01 June 1986

Pharmacokinetics of oral all-trans retinoic acid in patients with acute promyelocytic leukemia

scientific article published on December 1, 1991

Phase 2 clinical trial of 5-azacitidine, valproic acid, and all-trans retinoic acid in patients with high-risk acute myeloid leukemia or myelodysplastic syndrome

scientific article

Phenotypic and functional characterization of bone marrow mesenchymal stem cells derived from patients with multiple myeloma

scientific article published on 09 November 2006

Physical and functional interactions between cellular retinoic acid binding protein II and the retinoic acid-dependent nuclear complex.

scientific article

Post transcriptional control of the epigenetic stem cell regulator PLZF by sirtuin and HDAC deacetylases

scientific article published on 24 September 2015

Potentiation of the store-operated calcium entry (SOCE) induces phytohemagglutinin-activated Jurkat T cell apoptosis.

scientific article published on 24 April 2015

Preclinical modeling of myelodysplastic syndromes

scientific article

Preliminary experience in external quality control of RT-PCR PML-RAR alpha detection in promyelocytic leukemia

scientific article published on 01 December 1998

Present results of the treatment of myelodysplastic syndromes with low-dose cytosine arabinoside. Preliminary results of a cooperative protocol (38 patients) and review of the literature

scientific article published on January 1987

Prognostic implication of FLT3 and Ras gene mutations in patients with acute promyelocytic leukemia (APL): a retrospective study from the European APL Group

article

Quality of Life in hematology: European Hematology Association theme of the year ... and years to come ⬇️

scientific article published on January 1, 2013

Quantitation of minimal residual disease in acute promyelocytic leukemia patients with t(15;17) translocation using real-time RT-PCR

scientific article published on 01 February 2000

Raising hematology's European voice: the importance of calling yourself a hematologist ⬇️

scientific article published on April 1, 2012

Rationale and efficacy of proteasome inhibitor combined with arsenic trioxide in the treatment of acute promyelocytic leukemia.

scientific article published on 02 September 2016

Reactive oxygen species, DNA damage, and error-prone repair: a model for genomic instability with progression in myeloid leukemia?

scientific article published on 01 September 2007

Regulation of the transcriptional activity of nuclear receptors by the MEK/ERK1/2 pathway

scientific article published on 18 August 2012

Relationship between elevated levels of the alpha 1 acid glycoprotein in chronic myelogenous leukemia in blast crisis and pharmacological resistance to imatinib (Gleevec) in vitro and in vivo.

scientific article published in November 2003

Remembering John M. Goldman.

scientific article

Response

Retinoic acid modulates RAR alpha and RAR beta receptors in human glioma cell lines.

scientific article published in July 1999

Retinoic acid receptor alpha (RAralpha) Mutations in Human Leukemia.

scientific article

Retinoic acid receptors: involvement in acute promyelocytic leukemia.

scientific article published on May 1994

Retinoic acid therapy for promyelocytic leukaemia

scientific article published on 01 September 1989

Retinoic acid-induced apoptosis in leukemia cells is mediated by paracrine action of tumor-selective death ligand TRAIL.

scientific article

Retinoic acids in the treatment of acute promyelocytic leukemia

scientific article published on 01 January 1990

Retinoid acid supports granulocytic but not erythroid differentiation of myeloid progenitors in normal bone marrow cells

scientific article published on 01 August 1993

Retinoids and differentiation treatment: a strategy for treatment in cancer.

scientific article published on November 1994

Retroviral Transfer and Long-Term Expression of the Adrenoleukodystrophy Gene in Human CD34+Cells ⬇️

scientific article published on May 1, 1998

Risk of leukemic transformation in PV and ET patients.

scientific article published in June 2004

Screening for G-CSF receptor mutations in patients with secondary myeloid or lymphoid transformation of severe congenital neutropenia. A report from the French neutropenia register

scientific article published on 01 September 2004

Simultaneous determination of all-trans and 13-cis retinoic acids and their 4-oxo metabolites by adsorption liquid chromatography after solid-phase extraction

scientific article published on 01 April 1995

Structure-activity relationships of aromatic retinoids on the differentiation of the human histiocytic lymphoma cell line U-937

scientific article published on 01 January 1986

Successful xenografts of AML3 samples in immunodeficient NOD/shi-SCID IL2Rγ−/− mice

scientific article published on 13 June 2012

TET2 gene sequencing may be helpful for myeloproliferative neoplasm diagnosis

scientific article published on 16 January 2014

Targetable Alterations in Adult Patients With Soft-Tissue Sarcomas: Insights for Personalized Therapy.

scientific article published in October 2018

Targeted immunotherapy in acute myeloblastic leukemia: from animals to humans.

scientific article

Telomerase targeting by retinoids in cells from patients with myeloid leukemias of various subtypes, not only APL.

scientific article published on April 2006

The JAK2 46/1 haplotype in splanchnic vein thrombosis.

scientific article

The PML-RARα fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR ⬇️

scientific article published on August 23, 1991

The V617F JAK2 mutation and the increase in platelet CD36 in essential thrombocythemia are unrelated events

scientific article published on 15 June 2007

The boron-oxygen core of borinate esters is responsible for the store-operated calcium entry potentiation ability

scientific article

The effect of anti-CD44 monoclonal antibodies on differentiation and proliferation of human acute myeloid leukemia cells

scientific article published in August 2004

The epigenetic regulator PLZF represses L1 retrotransposition in germ and progenitor cells

scientific article published on 31 May 2013

The novel co‐activator CRABPII binds to RARα and RXRα via two nuclear receptor interacting domains and does not require the AF‐2 ‘core’ ⬇️

scientific article published on October 19, 2001

Towards a personalized pretransplantation conditioning in patients with myelodysplastic syndromes

scientific article published on 31 January 2018

Tracking the extramedullary PML-RARα-positive cell reservoirs in a preclinical model: Biomarker of long-term drug efficacy ⬇️

scientific article published on August 11, 2012

Transcriptional repression of microRNA genes by PML-RARA increases expression of key cancer proteins in acute promyelocytic leukemia

scientific article published on 21 October 2008

Transient hematologic and clinical effect of E21R in a child with end-stage juvenile myelomonocytic leukemia.

scientific article published in April 2002

Treatment of acute promyelocytic leukaemia.

scientific article

Treatment of first relapse in acute promyelocytic leukaemia with all-trans retinoic acid.

scientific article

Treatment of newly diagnosed acute promyelocytic leukemia (APL) by all transretinoic acid (ATRA) combined with chemotherapy: The European experience. European APL Group

article published in 1995

Treatment of polycythemia vera with hydroxyurea and pipobroman: final results of a randomized trial initiated in 1980.

scientific article published on 12 September 2011

Treatment of relapsing acute promyelocytic leukemia by all-trans retinoic acid therapy followed by timed sequential chemotherapy and stem cell transplantation. APL Study Group. Acute promyelocytic leukemia

scientific article published on 01 June 2000

Tretinoin with chemotherapy in newly diagnosed acute promyelocytic leukaemia. European APL Group

scientific article published on 01 April 1994

Type III aminoterminal propeptide of procollagen in some haematological malignancies

scientific article published on 01 March 1986

UV and clean air result in contamination-free PCR

scientific article published on 01 November 1999

Unexplained thrombocytosis: association of Baltimore polymorphism with germline MPL nonsense mutation.

scientific article

Use of animal models for the treatment of leukemias: Efficacy of DNA vaccination combined with ATRA.

scientific article published on February 2004

Use of the 46/1 haplotype to model JAK2(V617F) clonal architecture in PV patients: clonal evolution and impact of IFNα treatment.

scientific article

When can real-time quantitative RT-PCR effectively define molecular relapse in acute promyelocytic leukemia patients? (Results of the French Belgian Swiss APL Group).

scientific article

Yeast Assay Highlights the Intrinsic Genomic Instability of Human PML Intron 6 over Intron 3 and the Role of Replication Fork Proteins

scientific article published on 8 June 2015

[Cutaneous necrosis of the breast: a complication of oral anticoagulant treatment]

scientific article published on 01 January 1983

[Gene therapy of adrenoleukodystrophy]

scientific article published on 01 January 1996

[Nuclear receptors and ontogenesis of the hematopoietic tissue]

scientific article published on 01 January 1995

[Retinoic acid: its properties]

scientific article published on 01 October 1989

[Treatment of malignant hemopathies with all transretinoic acid]

scientific article published on 01 October 1997

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