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List of works by Luigi Messori

(S)-(+)-2-[2-(Biphenyl-2-yl)-1-methylethyl]-4,5-dihydro-1H-imidazolium hydrogen oxalate

2D-DIGE analysis of ovarian cancer cell responses to cytotoxic gold compounds

scientific article

A BINOL-based chiral polyammonium receptor for highly enantioselective recognition and fluorescence sensing of (S,S)-tartaric acid in aqueous solution

article

A case of extensive protein platination: the reaction of lysozyme with a Pt(ii)–terpyridine complex

scientific article published on 01 July 2018

A comparative study of adduct formation between the anticancer ruthenium(III) compound HInd trans-[RuCl4(Ind)2] and serum proteins.

scientific article

A comparative study of aluminum(III), gallium(III), indium(III), and thallium(III) binding to human serum transferrin

scholarly article by Wesley R Harris & Luigi Messori published June 2002 in Coordination Chemistry Reviews

A gold-containing drug against parasitic polyamine metabolism: the X-ray structure of trypanothione reductase from Leishmania infantum in complex with auranofin reveals a dual mechanism of enzyme inhibition

scientific article

A multi-technique approach to predicting the molecular structure of cuprizone in the gas phase and in the crystalline state

A novel class of peptides with facilitating action on neuronal nicotinic receptors of rat chromaffin cells in vitro: functional and molecular dynamics studies

scientific article published in January 2002

A spectroscopic study of the reaction of NAMI, a novel ruthenium(III)anti-neoplastic complex, with bovine serum albumin

scientific article published on 01 February 2000

A two-dimensional NMR study of Co(II)7 rabbit liver metallothionein

scientific article published on 01 January 1993

Acid-sensitive polyethylene glycol conjugates of doxorubicin: preparation, in vitro efficacy and intracellular distribution

article

Activity of Rat Cytosolic Thioredoxin Reductase Is Strongly Decreased bytrans-[Bis(2-amino-5- methylthiazole)tetrachlororuthenate(III)]: First Report of Relevant Thioredoxin Reductase Inhibition for a Ruthenium Compound

scientific article published on 02 November 2007

Alkyne Functionalization of a Photoactivated Ruthenium Polypyridyl Complex for Click-Enabled Serum Albumin Interaction Studies

scientific article published on 12 May 2020

Aluminum, copper, iron and zinc differentially alter amyloid-Aβ(1-42) aggregation and toxicity

scientific article published on 3 March 2011

Antiangiogenic properties of selected ruthenium(III) complexes that are nitric oxide scavengers.

scientific article published on May 2003

Antimalarial properties of green tea.

scientific article published on 11 December 2006

Antiproliferative Properties of a Few Auranofin-Related Gold(I) and Silver(I) Complexes in Leukemia Cells and their Interferences with the Ubiquitin Proteasome System

scientific article published on 28 September 2020

Arsenoplatin-1 Is a Dual Pharmacophore Anticancer Agent

scientific article published on 15 April 2019

Auranofin and its Analogues Show Potent Antimicrobial Activity against Multidrug-Resistant Pathogens: Structure-Activity Relationships

scientific article published on 05 November 2018

Biological properties of two gold(III) complexes: AuCl3 (Hpm) and AuCl2 (pm)

scientific article published on 01 May 1997

Biological role of adduct formation of the ruthenium(III) complex NAMI-A with serum albumin and serum transferrin.

scientific article published on November 2003

Biophysical characterisation of adducts formed between anticancer metallodrugs and selected proteins: new insights from X-ray diffraction and mass spectrometry studies

scientific article published on 08 January 2008

Butyltin(IV) benzoates: inhibition of thioredoxin reductase, tumor cell growth inhibition, and interactions with proteins

scientific article published on 23 December 2012

Cell and Cell-Free Mechanistic Studies on Two Gold(III) Complexes with Proven Antitumor Properties

Challenges associated with metal chelation therapy in Alzheimer's disease

scientific article

Chelation therapy for neurodegenerative diseases

scientific article published on July 2009

Chemistry and biology of three representative gold(III) compounds as prospective anticancer agents

Chemistry, antiproliferative properties, tumor selectivity, and molecular mechanisms of novel gold(III) compounds for cancer treatment: a systematic study

scientific article

Clioquinol decreases amyloid-beta burden and reduces working memory impairment in a transgenic mouse model of Alzheimer's disease

scientific article

Clioquinol, a drug for Alzheimer's disease specifically interfering with brain metal metabolism: structural characterization of its zinc(II) and copper(II) complexes

scientific article

Comparison of the Antiproliferative Activity of Two Antitumour Ruthenium(III) Complexes With Their Apotransferrin and Transferrin-Bound Forms in a Human Colon Cancer Cell Line.

scientific article

Conjugates of Gold Nanoparticles and Antitumor Gold(III) Complexes as a Tool for Their AFM and SERS Detection in Biological Tissue ⬇️

scientific article published on 13 December 2019

Controlling with light the interaction between trans-tetrapyridyl ruthenium complexes and an oligonucleotide

scientific article published on 12 December 2017

Copper and zinc dismetabolism in the mouse brain upon chronic cuprizone treatment.

scientific article published in July 2005

Crystallographic evidence for decomposition of dimethylformamide in the presence of ruthenium(III) chloride

article

Cytotoxic Profile and Peculiar Reactivity with Biomolecules of a Novel "Rule-Breaker" Iodidoplatinum(II) Complex

scientific article published on 21 July 2010

DOTAP/DOPE and DC-Chol/DOPE lipoplexes for gene delivery studied by circular dichroism and other biophysical techniques

article

Decomposition of ascorbic acid in the presence of cadmium ions leads to formation of a polymeric cadmium oxalate species with peculiar structural features

scientific article published in August 2002

ESI MS studies highlight the selective interaction of Auranofin with protein free thiols

scientific article published on 21 April 2020

ESI mass spectrometry and X-ray diffraction studies of adducts between anticancer platinum drugs and hen egg white lysozyme

scientific article

ESI–MS Characterisation of Protein Adducts of Anticancer Ruthenium(II)-Arene PTA (RAPTA) Complexes

scientific article published on 01 May 2007

EXAFS studies on copper transferrin

EXAFS studies on the oxalate adduct of iron transferrin

Effects of chronic treatment with sodium tetrachloroaurate(III) in mice and membrane models

scientific article published on 01 December 2004

Emerging protein targets for anticancer metallodrugs: inhibition of thioredoxin reductase and cathepsin B by antitumor ruthenium(II)-arene compounds

scientific article published on 4 October 2008

Exploiting soft and hard X-ray absorption spectroscopy to characterize metallodrug/protein interactions: the binding of [trans-RuCl4(Im)(dimethylsulfoxide)][ImH] (Im = imidazole) to bovine serum albumin

scientific article published on 23 August 2008

Exploring Metallodrug–Protein Interactions by ESI Mass Spectrometry: The Reaction of Anticancer Platinum Drugs with Horse Heart Cytochrome c

scholarly article by Angela Casini et al published 10 April 2006 in ChemMedChem

Exploring metallodrug-protein interactions by mass spectrometry: comparisons between platinum coordination complexes and an organometallic ruthenium compound

scientific article published on 14 March 2009

Exploring the Reactions of β-Amyloid (Aβ) Peptide 1–28 with AlIIIand FeIIIIons

scientific article published on 30 June 2011

Exploring the biochemical mechanisms of cytotoxic gold compounds: a proteomic study

scientific article

Formation of Supramolecular Structures between DNA and Starburst Dendrimers Studied by EPR, CD, UV, and Melting Profiles

Formation of titanium(IV) transferrin by reaction of human serum apotransferrin with titanium complexes

scientific article published on 01 January 1999

Gold complexes inhibit mitochondrial thioredoxin reductase: consequences on mitochondrial functions

scientific article published in October 2004

Gold compounds as anticancer agents: chemistry, cellular pharmacology, and preclinical studies

scientific article published on May 2010

Gold compounds as cysteine protease inhibitors: perspectives for pharmaceutical application as antiparasitic agents

scientific article

Gold(III) complexes with 2-substituted pyridines as experimental anticancer agents: solution behavior, reactions with model proteins, antiproliferative properties

scientific article

Gold(III) complexes with bipyridyl ligands: solution chemistry, cytotoxicity, and DNA binding properties

scientific article

Gold(III) compounds as anticancer agents: relevance of gold-protein interactions for their mechanism of action

scientific article published on 28 November 2007

Hypericins and thioredoxin reductase: Biochemical and docking studies disclose the molecular basis for effective inhibition by naphthodianthrones

scientific article

Impact of ring size on the copper(II) coordination abilities of cyclic tetrapeptides.

scientific article

Insights into the molecular mechanisms of protein platination from a case study: the reaction of anticancer platinum(II) iminoethers with horse heart cytochrome c.

scientific article published on 9 October 2007

Interaction of a gold(i) dicarbene anticancer drug with human telomeric DNA G-quadruplex: solution and computationally aided X-ray diffraction analysis

Interactions of Selected Gold(III) Complexes with Calf Thymus DNA

scientific article published on 01 February 2001

Investigation of the effects of copper ions on protein aggregation using a model system.

scientific article published in April 2004

Mass spectrometric analysis of ubiquitin–platinum interactions of leading anticancer drugs: MALDI versus ESI

article

Mechanisms of cytotoxicity of selected organogold(III) compounds

scientific article published on October 2005

Mechanistic studies on two dinuclear organogold(III) compounds showing appreciable antiproliferative properties and a high redox stability

scientific article

Medicinal gold compounds form tight adducts with the copper chaperone Atox-1: biological and pharmacological implications

scientific article published on 01 December 2012

Metal compounds as inhibitors of β-amyloid aggregation. Perspectives for an innovative metallotherapeutics on Alzheimer's disease

scholarly article by Daniela Valensin et al published October 2012 in Coordination Chemistry Reviews

Metal ion physiopathology in neurodegenerative disorders

scientific article

Metal-Induced Conformational Heterogeneity of Transferrins: A Spectroscopic Study of Indium(III) and Other Metal(III)-Substituted Transferrins

scientific article published on 01 January 1995

Metal-based compounds as prospective antileishmanial agents: inhibition of trypanothione reductase by selected gold complexes

scientific article published on 23 August 2013

Metal-based drugs for malaria, trypanosomiasis and leishmaniasis: recent achievements and perspectives

scientific article

Modeling of copper(II) sites in proteins based on histidyl and glycyl residues

scientific article published in November 2003

Molecular Mechanisms and Proposed Targets for Selected Anticancer Gold Compounds ⬇️

scientific article published on January 1, 2011

Molecular recognition of metal complexes by DNA: a comparative study of the interactions of the parent complexes [PtCl(TERPY)]Cl and [AuCl(TERPY)]Cl2 with double stranded DNA.

scientific article published in January 2005

Molecular structure, solution chemistry and biological properties of the novel [ImH][trans-IrCl(4)(Im)(DMSO)], (I) and of the orange form of [(DMSO)(2)H][trans-IrCl(4)(DMSO)(2)], (II), complexes

scientific article published in May 2003

NAMI-A and KP1019/1339, Two Iconic Ruthenium Anticancer Drug Candidates Face-to-Face: A Case Story in Medicinal Inorganic Chemistry

scientific article published on 24 May 2019

Native mass spectrometry of human carbonic anhydrase I and its inhibitor complexes

scientific article published on 14 September 2020

New Copper(II)/Cyclic Tetrapeptide System That Easily Oxidizes to Copper(III) under Atmospheric Oxygen

scientific article published on 03 November 2007

New platinum-oxicam complexes as anti-cancer drugs. Synthesis, characterization, release studies from smart hydrogels, evaluation of reactivity with selected proteins and cytotoxic activity in vitro

scientific article published on 27 March 2010

New uses for old drugs. Auranofin, a clinically established antiarthritic metallodrug, exhibits potent antimalarial effects in vitro: Mechanistic and pharmacological implications

scientific article published on 21 February 2008

On the Different Mode of Action of Au(I)/Ag(I)-NHC Bis-Anthracenyl Complexes Towards Selected Target Biomolecules

scientific article published on 20 November 2020

Outstanding plasmodicidal properties within a small panel of metallic compounds: Hints for the development of new metal-based antimalarials

scientific article published on 17 October 2008

Peculiar mechanistic and structural features of the carboplatin-cytochrome c system revealed by ESI-MS analysis

scientific article

Potential pathogenic role of beta-amyloid(1-42)-aluminum complex in Alzheimer's disease

scientific article published on 22 October 2007

Proanthocyanidin glycosides from the leaves of Quercus ilex L. (Fagaceae)

Promising in Vitro anti-Alzheimer Properties for a Ruthenium(III) Complex

scientific article

Protein interactions of dirhodium tetraacetate: a structural study

scientific article published on 01 February 2020

Protein metalation by metal-based drugs: X-ray crystallography and mass spectrometry studies.

scientific article

Protein metalation by metal-based drugs: reactions of cytotoxic gold compounds with cytochrome c and lysozyme

scientific article published on 07 November 2012

Proteomic analysis of ovarian cancer cell responses to cytotoxic gold compounds

scientific article published on 10 February 2012

Rationalization of the inhibition activity of structurally related organometallic compounds against the drug target cathepsin B by DFT.

scientific article published on 14 May 2010

Reaction with Proteins of a Five-Coordinate Platinum(II) Compound ⬇️

journal article from 'International Journal of Molecular Sciences' published in 2019

Reactions of a tetranuclear Pt-thiosemicarbazone complex with model proteins

scientific article published on 10 January 2018

Reactions of gold(III) complexes with serum albumin

scientific article published on 01 December 2003

Reactions of medicinally relevant gold compounds with the C-terminal motif of thioredoxin reductase elucidated by MS analysis

article

Reactions of metallodrugs with proteins: selective binding of phosphane-based platinum(ii) dichlorides to horse heart cytochrome c probed by ESI MS coupled to enzymatic cleavage

scientific article published on 22 September 2011

Reactivity and biological properties of a series of cytotoxic PtI2(amine)2 complexes, either cis or trans configured

scientific article

Reactivity of an antimetastatic organometallic ruthenium compound with metallothionein-2: relevance to the mechanism of action

scientific article published on 11 August 2009

Ruthenium anticancer drugs and proteins: a study of the interactions of the ruthenium(III) complex imidazolium trans-[tetrachloro(dimethyl sulfoxide)(imidazole)ruthenate(III)] with hen egg white lysozyme and horse heart cytochrome c

scholarly article by Angela Casini et al published 7 August 2007 in Journal of Biological Inorganic Chemistry

Selected cytotoxic gold compounds cause significant inhibition of 20S proteasome catalytic activities

scientific article published on 11 August 2014

Selected gold compounds cause pronounced inhibition of Falcipain 2 and effectively block P. falciparum growth in vitro

scientific article published on 10 September 2011

Short-chain oligopeptides with copper(II) binding properties: The impact of specific structural modifications on the copper(II) coordination abilities

scientific article published on 9 January 2009

Simple and rapid physico-chemical methods to examine action of antimalarial drugs with hemin: its application to Artemisia annua constituents

scientific article published in January 2002

Solution NMR Structure of a Ligand/Hybrid-2-G-Quadruplex Complex Reveals Rearrangements that Affect Ligand Binding

Solution NMR Structure of a Ligand/Hybrid-2-G-Quadruplex Complex Reveals Rearrangements that Affect Ligand Binding.

scientific article published on 19 May 2017

Solution behaviour and biomolecular interactions of two cytotoxic trans-platinum(II) complexes bearing aliphatic amine ligands

scientific article

Solution chemistry and cytotoxic properties of novel organogold(III) compounds

scientific article

Solution studies of the antitumor complex dichloro 1,2-propylendiaminetetraacetate ruthenium (III) and of its interactions with proteins

scientific article published on 01 August 1998

Spectral characterization of ruthenium(III) transferrin

scientific article published on 01 February 1993

Spectral characterization of vanadium-transferrin systems

Spectrophotometric and ESI-MS/HPLC studies reveal a common mechanism for the reaction of various artemisinin analogues with hemin

scientific article published in November 2003

Spectroscopic and potentiometric study of the SOD mimic system copper(II)/acetyl-L-histidylglycyl-L-histidylglycine.

scientific article

Stability of an organometallic ruthenium-ubiquitin adduct in the presence of glutathione: relevance to antitumour activity

scientific article published on 23 August 2008

Structural Characterization of a Gold/Serum Albumin Complex

scientific article published on 30 July 2019

Structural and solution chemistry, antiproliferative effects, and DNA and protein binding properties of a series of dinuclear gold(III) compounds with bipyridyl ligands

scientific article published on September 2006

Structural and solution chemistry, protein binding and antiproliferative profiles of gold(I)/(III) complexes bearing the saccharinato ligand

scientific article published on 30 November 2010

Structural characterization, solution studies, and DFT calculations on a series of binuclear gold(III) oxo complexes: relationships to biological properties

scientific article

Structural effects of titanium citrate on the human erythrocyte membrane.

scientific article published on 5 January 2005

Structural features of a new dinuclear platinum(II) complex with significant antiproliferative activity

scientific article published in October 2003

Structural investigation of cisplatin-protein interactions: selective platination of His19 in a cuprozinc superoxide dismutase

scientific article published in February 2006

Structure of a terbium(III)-quinizarine complex: the first crystallographic model for metalloanthracyclines

scientific article published in May 2003

Structure, solution chemistry, antiproliferative actions and protein binding properties of non-conventional platinum(II) compounds with sulfur and phosphorus donors

scientific article published on 6 January 2011

Structure-activity relationships in a series of auranofin analogues showing remarkable antiproliferative properties

scientific article published on 28 March 2020

Structure-function relationships within Keppler-type antitumor ruthenium(III) complexes: the case of 2-aminothiazolium[trans-tetrachlorobis(2-aminothiazole)ruthenate(III)].

scientific article published in July 2005

Study of ruthenium(II) complexes with anticancer drugs as ligands. Design of metal-based phototherapeutic agents

scientific article published in December 2003

Synthesis and Mode of Action Studies on Iridium(I)-NHC Anticancer Drug Candidates

scholarly article by Yvonne Gothe et al published 24 May 2018 in European Journal of Inorganic Chemistry

Synthesis, structural characterization, solution behavior, and in vitro antiproliferative properties of a series of gold complexes with 2-(2'-pyridyl)benzimidazole as ligand: comparisons of gold(III) versus gold(I) and mononuclear versus binuclear d

scientific article

Synthesis, structural characterization, solution chemistry, and preliminary biological studies of the ruthenium(III) complexes [TzH][trans-RuCl4(Tz)2] and [TzH][trans-RuCl4(DMSO)(Tz)].(DMSO), the thiazole analogues of antitumor ICR and NAMI-A.

scientific article

The C2 variant of human serum transferrin retains the iron binding properties of the native protein.

scientific article published in September 2005

The NAMI A – human ferritin system: a biophysical characterization

scientific article published on 01 August 2018

The copper(II) binding properties of the cyclic peptide c(HGHK).

scientific article published in December 2004

The copper(II) coordination abilities of three novel cyclic tetrapeptides with -His-Xaa-His- motif

scientific article published on 21 November 2006

The crystal structure of the complex between a disaccharide anthracycline and the DNA hexamer d(CGATCG) reveals two different binding sites involving two DNA duplexes

scientific article (publication date: March 2003)

The disaccharide anthracycline MEN 10755 binds human serum albumin to a non-classical drug binding site

scientific article

The first step of arsenoplatin-1 aggregation in solution unveiled by solving the crystal structure of its protein adduct

scientific article published on 15 December 2020

The influence of auranofin, a clinically established antiarthritic gold drug, on bone metabolism: analysis of its effects on human multipotent adipose-derived stem cells, taken as a model

scientific article published in August 2008

The mode of action of anticancer gold-based drugs: a structural perspective

scientific article

The molecular mechanisms of antimetastatic ruthenium compounds explored through DIGE proteomics

scientific article

The pH dependent properties of metallotransferrins: a comparative study

scientific article published on 01 October 1997

The reaction of artemisinin with hemin: a further insight into the mechanism

The reaction of artemisinins with hemoglobin: a unified picture

scientific article published on 10 January 2006

The x-ray structure of the adduct between NAMI-A and carbonic anhydrase provides insights into the reactivity of this metallodrug with proteins

scientific article

Thioredoxin reductase, an emerging target for anticancer metallodrugs. Enzyme inhibition by cytotoxic gold(iii) compounds studied with combined mass spectrometry and biochemical assays

Thioredoxin reductase: A target for gold compounds acting as potential anticancer drugs

Trace copper(II) or zinc(II) ions drastically modify the aggregation behavior of amyloid-beta1-42: an AFM study

scientific article

Trans-cis-cis-[RuCl2(DMSO)2(2-amino-5-methyl-thiazole)2], (PMRu52), a novel ruthenium(II) compound acting as a strong inhibitor of cathepsin B.

scientific article published on 9 October 2009

Unravelling the chemical nature of copper cuprizone

scientific article published on 11 April 2007

[Au2(phen(2Me))2(μ-O)2](PF6)2, a Novel Dinuclear Gold(III) Complex Showing Excellent Antiproliferative Properties

scientific article published on 2 July 2010

fac-{Ru(CO)(3)}(2+) selectively targets the histidine residues of the beta-amyloid peptide 1-28. Implications for new Alzheimer's disease treatments based on ruthenium complexes

scientific article published in June 2010

fac-{Ru(CO)3}2+-core complexes and design of metal-based drugs. synthesis, structure, and reactivity of Ru-thiazole derivative with serum proteins and absorption-release studies with acryloyl and silica hydrogels as carriers in physiological media

scientific article published in January 2007

pH-dependent properties of cobalt(II) carboxypeptidase A-inhibitor complexes

scientific article published on 01 April 1992

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