List of works - Nicola Micale

1-Aryl-6,7-methylenedioxy-3 H -quinazolin-4-ones as anticonvulsant agents

scientific article published on 01 December 2003

5-phenyl-9H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-8(7H)-one.

scientific article published on 11 February 2003

7,8-Methylenedioxy-4H-2,3-benzodiazepin-4-ones as novel AMPA receptor antagonists

scientific article published on 01 April 1998

A SIMPLE AND EFFICIENT SYNTHESIS OF GYKI 52466 AND GYKI 52895

Antiproliferative Properties of a Few Auranofin-Related Gold(I) and Silver(I) Complexes in Leukemia Cells and their Interferences with the Ubiquitin Proteasome System

scientific article published on 28 September 2020

Characterization of the mechanism of anticonvulsant activity for a selected set of putative AMPA receptor antagonists

scientific article

Constrained peptidomimetics as antiplasmodial falcipain-2 inhibitors

scientific article published on 10 June 2010

Copper(ii) complexes with tridentate halogen-substituted Schiff base ligands: synthesis, crystal structures and investigating the effect of halogenation, leaving groups and ligand flexibility on antiproliferative activities

scientific article

Design and synthesis of a potent and selective peptidomimetic inhibitor of caspase-3.

scientific article

Design of 1-substituted 2-arylmethyl-4,5-methylenedioxybenzene derivatives as antiseizure agents.

scientific article

Development of Novel Peptidomimetics Containing a Vinyl Sulfone Moiety as Proteasome Inhibitors

article

Development of novel selective peptidomimetics containing a boronic acid moiety, targeting the 20S proteasome as anticancer agents

scientific article

Development of peptidomimetic boronates as proteasome inhibitors

article

Development of peptidomimetics with a vinyl sulfone warhead as irreversible falcipain-2 inhibitors.

scientific article published on 31 January 2008

Direct and Chemoselective Synthesis of Tertiary Difluoroketones via Weinreb Amide Homologation with a CHF2-Carbene Equivalent

scientific article published on 10 October 2019

Discovery of benzimidazole-based L. mexicana cysteine protease CPB2.8ΔCTE inhibitors as potential therapeutics for leishmaniasis.

scientific article published on 4 May 2018

Enantioselective recognition of 2,3-benzodiazepin-4-one derivatives with anticonvulsant activity on several polysaccharide chiral stationary phases

scientific article published on 24 May 2006

Enantioseparation, absolute configuration determination, and anticonvulsant activity of (±)-1-(4-aminophenyl)-7,8-methylenedioxy-1,2,3,5-tetrahydro-4H-2,3-benzodiazepin-4-one

scientific article published on 01 January 2007

Hydrogels for the Delivery of Plant-Derived (Poly)Phenols

scientific article published on 16 July 2020

Hydroxamic Acid-Based Histone Deacetylase (HDAC) Inhibitors Bearing a Pyrazole Scaffold and a Cinnamoyl Linker

scientific article published on 21 February 2019

Identification of a new series of amides as non-covalent proteasome inhibitors.

scientific article published on 25 January 2014

Inhibition of rhodesain as a novel therapeutic modality for human African trypanosomiasis

scientific article published on 7 May 2013

Mechanism of Inhibition of the GluA2 AMPA Receptor Channel Opening: the Role of 4-Methyl versus 4-Carbonyl Group on the Diazepine Ring of 2,3-Benzodiazepine Derivatives.

scientific article

Mechanism of falcipain-2 inhibition by α,β-unsaturated benzo[1,4]diazepin-2-one methyl ester

scientific article published on 11 September 2012

Mechanism of inhibition of GluA2 AMPA receptor channel opening by 2,3-benzodiazepine derivatives: functional consequences of replacing a 7,8-methylenedioxy with a 7,8-ethylenedioxy moiety

scientific article

New 7,8-ethylenedioxy-2,3-benzodiazepines as noncompetitive AMPA receptor antagonists

scientific article

Nonpeptidic vinyl and allyl phosphonates as falcipain-2 inhibitors

scientific article published on July 2008

Novel 2H-isoquinolin-3-ones as antiplasmodial falcipain-2 inhibitors.

scientific article published on 12 August 2009

Novel Peptidomimetic Cysteine Protease Inhibitors as Potential Antimalarial Agents

scientific article published on 01 June 2006

Novel peptidomimetics containing a vinyl ester moiety as highly potent and selective falcipain-2 inhibitors.

scientific article published on April 2009

Novel potent AMPA/kainate receptor antagonists: synthesis and anticonvulsant activity of a series of 2-[(4-alkylsemicarbazono)-(4-amino-phenyl)methyl]-4,5-methylenedioxyphenylacetic acid alkyl esters

scientific article published in September 2002

Optimization of peptidomimetic boronates bearing a P3 bicyclic scaffold as proteasome inhibitors

scientific article

Peptide-based proteasome inhibitors in anticancer drug design.

scientific article published on March 2014

Peptidomimetics containing a vinyl ketone warhead as falcipain-2 inhibitors

scientific article published on 03 March 2011

Peptidyl Fluoromethyl Ketones and Their Applications in Medicinal Chemistry

scientific article published on 03 September 2020

Ruthenium(ii) and palladium(ii) homo- and heterobimetallic complexes: synthesis, crystal structures, theoretical calculations and biological studies

scientific article published on 16 October 2019

Selected cytotoxic gold compounds cause significant inhibition of 20S proteasome catalytic activities

scientific article published on 11 August 2014

Selected gold compounds cause pronounced inhibition of Falcipain 2 and effectively block P. falciparum growth in vitro

scientific article published on 10 September 2011

Subunit-specific agonist activity at NR2A-, NR2B-, NR2C-, and NR2D-containing N-methyl-D-aspartate glutamate receptors

scientific article published on 10 July 2007

Synthesis and Anti-HIV Profile of a Novel Tetrahydroindazolylbenzamide Derivative Obtained by Oxazolone Chemistry

scientific article published on 15 December 2018

Synthesis and Anticonvulsant Activity of Novel and Potent 2,3-Benzodiazepine AMPA/Kainate Receptor Antagonists

scientific article published on 01 October 1999

Synthesis and anticonvulsant activity of new 2,3-benzodiazepines as AMPA receptor antagonists

scientific article published on 01 March 1999

Synthesis and anticonvulsant activity of novel and potent 1-aryl-7,8-methylenedioxy-1,2,3,5-tetrahydro-4H-2,3-benzodiazepin-4-ones

scientific article published on 01 February 2001

Synthesis and antitumor activity of 1,3-benzodioxole derivatives.

scientific article published in October 2002

Synthesis and cytotoxic activity of 1,3-benzodioxole derivatives. Note II.

scientific article published on May 2003

Synthesis and in vitro antitumour activity evaluation of 1-aryl-1H,3H-thiazolo[4,3-b]quinazolines

scientific article published on 01 December 2000

Synthesis and molecular modeling studies of derivatives of a highly potent peptidomimetic vinyl ester as falcipain-2 inhibitors.

scientific article

Synthesis of 2-semicarbazonomethyl-4,5-methylenedioxyphenylacetic acids as anticonvulsant agents

scientific article published on 01 March 2005

Synthesis of C3/C1-Substituted Tetrahydroisoquinolines.

scientific article published on 14 August 2015

Synthesis of Novel 3-(Alkylcarbamoyl)-2-aryl-1,2-dihydro-6,7-(methylenedioxy)-3H-quinazolin-4-ones as Anticonvulsant Agents

scientific article published on 01 March 2006

Synthesis of novel peptidomimetics as inhibitors of protozoan cysteine proteases falcipain-2 and rhodesain

scientific article published on 14 April 2010

Synthesis, Chiral Resolution and Pharmacological Evaluation of a 2,3-Benzodiazepine-Derived Noncompetitive AMPA Receptor Antagonist

scientific article published on 01 March 2009

Synthesis, chiral resolution, and enantiopharmacology of a potent 2,3-benzodiazepine derivative as noncompetitive AMPA receptor antagonist.

scientific article published in January 2006

List of works by Nicola Micale

1-Aryl-6,7-methylenedioxy-3 H -quinazolin-4-ones as anticonvulsant agents

5-phenyl-9H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-8(7H)-one.

7,8-Methylenedioxy-4H-2,3-benzodiazepin-4-ones as novel AMPA receptor antagonists

A SIMPLE AND EFFICIENT SYNTHESIS OF GYKI 52466 AND GYKI 52895

Antiproliferative Properties of a Few Auranofin-Related Gold(I) and Silver(I) Complexes in Leukemia Cells and their Interferences with the Ubiquitin Proteasome System

Characterization of the mechanism of anticonvulsant activity for a selected set of putative AMPA receptor antagonists

Constrained peptidomimetics as antiplasmodial falcipain-2 inhibitors

Copper(ii) complexes with tridentate halogen-substituted Schiff base ligands: synthesis, crystal structures and investigating the effect of halogenation, leaving groups and ligand flexibility on antiproliferative activities

Design and synthesis of a potent and selective peptidomimetic inhibitor of caspase-3.

Design of 1-substituted 2-arylmethyl-4,5-methylenedioxybenzene derivatives as antiseizure agents.

Development of Novel Peptidomimetics Containing a Vinyl Sulfone Moiety as Proteasome Inhibitors

Development of novel selective peptidomimetics containing a boronic acid moiety, targeting the 20S proteasome as anticancer agents

Development of peptidomimetic boronates as proteasome inhibitors

Development of peptidomimetics with a vinyl sulfone warhead as irreversible falcipain-2 inhibitors.

Direct and Chemoselective Synthesis of Tertiary Difluoroketones via Weinreb Amide Homologation with a CHF2-Carbene Equivalent

Discovery of benzimidazole-based L. mexicana cysteine protease CPB2.8ΔCTE inhibitors as potential therapeutics for leishmaniasis.

Enantioselective recognition of 2,3-benzodiazepin-4-one derivatives with anticonvulsant activity on several polysaccharide chiral stationary phases

Enantioseparation, absolute configuration determination, and anticonvulsant activity of (±)-1-(4-aminophenyl)-7,8-methylenedioxy-1,2,3,5-tetrahydro-4H-2,3-benzodiazepin-4-one

Hydrogels for the Delivery of Plant-Derived (Poly)Phenols

Hydroxamic Acid-Based Histone Deacetylase (HDAC) Inhibitors Bearing a Pyrazole Scaffold and a Cinnamoyl Linker

Identification of a new series of amides as non-covalent proteasome inhibitors.

Inhibition of rhodesain as a novel therapeutic modality for human African trypanosomiasis

Mechanism of Inhibition of the GluA2 AMPA Receptor Channel Opening: the Role of 4-Methyl versus 4-Carbonyl Group on the Diazepine Ring of 2,3-Benzodiazepine Derivatives.

Mechanism of falcipain-2 inhibition by α,β-unsaturated benzo[1,4]diazepin-2-one methyl ester

Mechanism of inhibition of GluA2 AMPA receptor channel opening by 2,3-benzodiazepine derivatives: functional consequences of replacing a 7,8-methylenedioxy with a 7,8-ethylenedioxy moiety

New 7,8-ethylenedioxy-2,3-benzodiazepines as noncompetitive AMPA receptor antagonists

Nonpeptidic vinyl and allyl phosphonates as falcipain-2 inhibitors

Novel 2H-isoquinolin-3-ones as antiplasmodial falcipain-2 inhibitors.

Novel Peptidomimetic Cysteine Protease Inhibitors as Potential Antimalarial Agents

Novel peptidomimetics containing a vinyl ester moiety as highly potent and selective falcipain-2 inhibitors.

Novel potent AMPA/kainate receptor antagonists: synthesis and anticonvulsant activity of a series of 2-[(4-alkylsemicarbazono)-(4-amino-phenyl)methyl]-4,5-methylenedioxyphenylacetic acid alkyl esters

Optimization of peptidomimetic boronates bearing a P3 bicyclic scaffold as proteasome inhibitors

Peptide-based proteasome inhibitors in anticancer drug design.

Peptidomimetics containing a vinyl ketone warhead as falcipain-2 inhibitors

Peptidyl Fluoromethyl Ketones and Their Applications in Medicinal Chemistry

Ruthenium(ii) and palladium(ii) homo- and heterobimetallic complexes: synthesis, crystal structures, theoretical calculations and biological studies

Selected cytotoxic gold compounds cause significant inhibition of 20S proteasome catalytic activities

Selected gold compounds cause pronounced inhibition of Falcipain 2 and effectively block P. falciparum growth in vitro

Subunit-specific agonist activity at NR2A-, NR2B-, NR2C-, and NR2D-containing N-methyl-D-aspartate glutamate receptors

Synthesis and Anti-HIV Profile of a Novel Tetrahydroindazolylbenzamide Derivative Obtained by Oxazolone Chemistry

Synthesis and Anticonvulsant Activity of Novel and Potent 2,3-Benzodiazepine AMPA/Kainate Receptor Antagonists

Synthesis and anticonvulsant activity of new 2,3-benzodiazepines as AMPA receptor antagonists

Synthesis and anticonvulsant activity of novel and potent 1-aryl-7,8-methylenedioxy-1,2,3,5-tetrahydro-4H-2,3-benzodiazepin-4-ones

Synthesis and antitumor activity of 1,3-benzodioxole derivatives.

Synthesis and cytotoxic activity of 1,3-benzodioxole derivatives. Note II.

Synthesis and in vitro antitumour activity evaluation of 1-aryl-1H,3H-thiazolo[4,3-b]quinazolines

Synthesis and molecular modeling studies of derivatives of a highly potent peptidomimetic vinyl ester as falcipain-2 inhibitors.

Synthesis of 2-semicarbazonomethyl-4,5-methylenedioxyphenylacetic acids as anticonvulsant agents

Synthesis of C3/C1-Substituted Tetrahydroisoquinolines.

Synthesis of Novel 3-(Alkylcarbamoyl)-2-aryl-1,2-dihydro-6,7-(methylenedioxy)-3H-quinazolin-4-ones as Anticonvulsant Agents

Synthesis of novel peptidomimetics as inhibitors of protozoan cysteine proteases falcipain-2 and rhodesain

Synthesis, Chiral Resolution and Pharmacological Evaluation of a 2,3-Benzodiazepine-Derived Noncompetitive AMPA Receptor Antagonist

Synthesis, chiral resolution, and enantiopharmacology of a potent 2,3-benzodiazepine derivative as noncompetitive AMPA receptor antagonist.