List of works - Sophie Susen

1/1 plasma to red blood cell ratio: an evidence-based practice?

scientific article published on 29 April 2011

A Laboratory Phenotype/Genotype Correlation of 1167 French Patients From 670 Families With von Willebrand Disease: A New Epidemiologic Picture

scientific article published on March 2016

A novel ELISA-based diagnosis of acquired von Willebrand disease with increased VWF proteolysis.

scientific article published on 21 January 2016

Acquired von Willebrand syndrome after continuous-flow mechanical device support contributes to a high prevalence of bleeding during long-term support and at the time of transplantation

scientific article

Acquired von Willebrand syndrome in aortic stenosis.

scientific article

Aldosterone, mortality, and acute ischaemic events in coronary artery disease patients outside the setting of acute myocardial infarction or heart failure

scientific article

Alterations in neutrophil production and function at an early stage in the high-fructose rat model of metabolic syndrome

scientific article published in August 2014

Ambivalent effect of aortic stenosis on von Willebrand factor and thrombin generation. Is transvalvular gradient the guilty party?

scientific article published on 02 September 2011

Antibody-Based Protection of von Willebrand Factor Degradation

scientific article published on 01 June 2016

Antibody-based prevention of von Willebrand factor degradation mediated by circulatory assist devices.

scientific article published on 17 July 2014

Are there any additional mechanisms for haemolysis in HELLP syndrome?

scientific article published on 9 April 2016

Arterial Pulsatility and Circulating von Willebrand Factor in Patients on Mechanical Circulatory Support

Atherosclerotic-like process in aortic stenosis: activation of the tissue factor-thrombin pathway and potential role through osteopontin alteration.

scientific article published on 04 August 2010

Beneficial effects of fenofibrate on plaque thrombogenicity and plaque stability in atherosclerotic rabbits

scientific article published on 23 April 2008

Bioprosthetic Total Artificial Heart Induces a Profile of Acquired Hemocompatibility With Membranes Recellularization

Blood outgrowth endothelial cells from cord blood and peripheral blood: angiogenesis-related characteristicsin vitro: a rebuttal

scientific article published on 01 March 2009

CT-ADP Point-of-Care Assay Predicts 30-Day Paravalvular Aortic Regurgitation and Bleeding Events following Transcatheter Aortic Valve Replacement

scientific article published on 28 March 2018

Circulatory support devices: fundamental aspects and clinical management of bleeding and thrombosis.

scientific article published on 25 August 2015

Clinical and prognostic implications of low or high level of von Willebrand factor in patients with Waldenstrom macroglobulinemia.

scientific article published on 14 August 2012

Clinico-Biological Features and Clonal Hematopoiesis in Patients with Severe COVID-19

scientific article published on 21 July 2020

Coagulation biomarkers are independent predictors of increased oxygen requirements in COVID-19

scientific article published on 17 August 2020

Comparison of blood activation in the wound, active vent, and cardiopulmonary bypass circuit

scientific article published on 01 August 2008

Compliance with evidence-based clinical management guidelines in bleeding trauma patients

scientific article published in November 2016

Decellularized heart valve as a scaffold for in vivo recellularization: deleterious effects of granulocyte colony-stimulating factor.

scientific article

Detection of monocyte tissue factor after endotoxin stimulation: comparison of one functional and three immunological methods

scientific article published on 01 July 1995

Dietary CML-enriched protein induces functional arterial aging in a RAGE-dependent manner in mice.

scientific article published on 20 March 2015

Dietary lipid lowering modifies plaque phenotype in rabbit atheroma after angioplasty: a potential role of tissue factor

scientific article published on 22 September 2003

Difference in mobilization of progenitor cells after myocardial infarction in smoking versus non-smoking patients: insights from the BONAMI trial.

scientific article

Drug-eluting stents: trading restenosis for thrombosis?

scientific article published on July 2007

Dyslipidemia shifts the tissue factor/tissue factor pathway inhibitor balance toward increased thrombogenicity in atherosclerotic plaques

Egfl7 Represses the Vasculogenic Potential of Human Endothelial Progenitor Cells

scientific article published on 4 October 2017

Endothelial progenitor cells are selectively mobilised immediately after coronary artery bypass grafting or valve surgery

Evaluation of dabigatran, rivaroxaban and apixaban target-specific assays in a multicenter French study.

scientific article published on 4 September 2017

Evidence for time-dependent activation of monocytes in the systemic circulation in unstable angina but not in acute myocardial infarction or in stable angina

scientific article published on 01 October 1994

Free leptin, carotid plaque phenotype and relevance to related symptomatology: insights from the OPAL-Lille carotid endarterectomy study

scientific article

French lyophilized plasma versus fresh frozen plasma for the initial management of trauma-induced coagulopathy: a randomized open-label trial.

scientific article published on 23 December 2017

Frequency of abdominal aortic aneurysm in patients undergoing coronary artery bypass grafting

scientific article published on 21 April 2010

From normal to pathological hemostasis.

scientific article published on June 2006

Functional impairment of von Willebrand factor in hypertrophic cardiomyopathy: relation to rest and exercise obstruction

scientific article published on 22 September 2008

Gastrointestinal bleeding from angiodysplasia in von Willebrand disease: improved diagnosis and outcome prediction using videocapsule on top of conventional endoscopy

scientific article published on 28 October 2020

Hemostasis and Thrombosis: Clinical Usefulness of Combined use of Platelet Aggregation Test and Anti PF4-H. Antibodies Elisa test for the Diagnosis of Heparin Induced Thrombocytopenia

scientific article

High-dose tranexamic acid reduces blood loss in postpartum haemorrhage

scientific article published on 15 April 2011

High-sensitivity C-reactive protein: potential adjunct for risk stratification in patients with stable congestive heart failure

scientific article published on 23 September 2005

Human Alternative Macrophages Populate Calcified Areas of Atherosclerotic Lesions and Display Impaired RANKL-Induced Osteoclastic Bone Resorption Activity

scientific article published on 24 April 2017

Identification of tissue factor in experimental aortic valve sclerosis

scientific article published on 6 March 2008

Immunomodulatory effect of pentoxifylline during human allograft rejection: involvement of tumor necrosis factor-alpha and adhesion molecules

scientific article published on 01 March 2000

Impact of initial clinical presentation on clopidogrel low response

scientific article published on 23 September 2013

In Response

scientific article published on 01 April 2015

In vivo autologous recellularization of a tissue-engineered heart valve: are bone marrow mesenchymal stem cells the best candidates?

scientific article published on 12 July 2007

Inflammation triggers colony forming endothelial cell mobilization after angioplasty in chronic lower limb ischemia

scientific article published on 01 January 2008

Inhibition of tissue factor-factor VIIa proteolytic activity blunts hepatic metastasis in colorectal cancer

scientific article

Interleukin 8 is differently expressed and modulated by PAR-1 activation in early and late endothelial progenitor cells.

scientific article published on 23 July 2008

Intracoronary autologous mononucleated bone marrow cell infusion for acute myocardial infarction: results of the randomized multicenter BONAMI trial

scientific article

Intraoperative cell savage for life-threatening haemorrhagic caesarean section

Intravenous thrombolysis for acute ischaemic stroke in patients on direct oral anticoagulants Expert opinion of the Societe Francaise de Neurologie Vasculaire (SFNV) [French Vascular Neurology Society] and the Groupe Francais d'etudes sur l'Hemostas

scientific article published on 23 January 2018

Leptin induces osteoblast differentiation of human valvular interstitial cells via the Akt and ERK pathways

scientific article published on 18 March 2017

Letters to the Editors: letter in response to Bhogal and colleagues

scientific article published on 18 September 2020

M1 and M2 macrophage proteolytic and angiogenic profile analysis in atherosclerotic patients reveals a distinctive profile in type 2 diabetes

article

Management Of Antiplatelet Therapy In Patients Undergoing Elective Invasive Procedures Proposals From The French Working Group On Perioperative Hemostasis (Gihp) And The French Study Group On Thrombosis And Hemostasis (Gfht) In Collaboration With Th

scientific article published on 5 January 2018

Management of Severe Bleeding in Patients Treated with Direct Oral Anticoagulants: An Observational Registry Analysis

scientific article published on 14 April 2017

Management of antiplatelet therapy in patients undergoing elective invasive procedures: Proposals from the French Working Group on perioperative hemostasis (GIHP) and the French Study Group on thrombosis and hemostasis (GFHT). In collaboration with

scientific article published on 03 February 2018

Management of bleeding and emergency invasive procedures in patients on dabigatran: Updated guidelines from the French Working Group on Perioperative Haemostasis (GIHP) - September 2016

scientific article published on 02 May 2018

Management of bleeding and invasive procedures in haemophilia A patients with inhibitor treated with emicizumab (Hemlibra® ): Proposals from the French network on inherited bleeding disorders (MHEMO), the French Reference Centre on Haemophilia, in c

scientific article published on 11 July 2019

Management of direct oral anticoagulants in patients undergoing elective surgeries and invasive procedures: Updated guidelines from the French Working Group on Perioperative Hemostasis (GIHP) - September 2015.

scientific article

Management of major bleeding complications and emergency surgery in patients on long-term treatment with direct oral anticoagulants, thrombin or factor-Xa inhibitors: proposals of the working group on perioperative haemostasis (GIHP) - March 2013.

scientific article published on 25 June 2013

Massive transfusion: assessing higher plasma: blood ratios and earlier plasma administration.

scientific article published in March 2011

Medical advances in the treatment of postpartum hemorrhage

scientific article

Meta-Analysis of Abdominal Aortic Aneurysm in Patients With Coronary Artery Disease

scientific article published on 14 August 2015

Metabolic syndrome and collateral vessel formation in patients with documented occluded coronary arteries: association with hyperglycaemia, insulin-resistance, adiponectin and plasminogen activator inhibitor-1.

scientific article published on 22 January 2009

Microparticle phenotypes are associated with driver mutations and distinct thrombotic risks in essential thrombocythemia.

scientific article published on 31 May 2016

Monocyte tissue factor response is decreased in patients with hyperlipidemia

scientific article published on 01 November 1999

On the versatility of von Willebrand factor

scientific article published on 10 July 2013

Pentoxifylline prevents upregulation of monocyte tissue factor in renal transplant recipients undergoing post-graft complications

scientific article published on 01 November 2000

Peripheral arterial revascularization: which antithrombotic agents?

scientific article (publication date: November 2001)

Plasma/platelets/red blood cell ratio in the management of the bleeding traumatized patient: does it matter?

scientific article published on April 2012

Poor agreement between light transmission aggregometry, Verify Now P2Y₁₂ and vasodilatator-stimulated phosphoprotein for clopidogrel low-response assessment: a potential explanation of negative results of recent randomized trials.

scientific article published on 31 October 2013

Position of the French Working Group on Perioperative Haemostasis (GIHP) on viscoelastic tests: what role for which indication in bleeding situations?

scientific article published on 17 January 2018

Postpartum haemorrhage related early increase in D-dimers is inhibited by tranexamic acid: haemostasis parameters of a randomized controlled open labelled trial.

scientific article

Postprocedural aortic regurgitation in balloon-expandable and self-expandable transcatheter aortic valve replacement procedures: analysis of predictors and impact on long-term mortality: insights from the FRANCE2 Registry.

scientific article

Prevention of thrombotic risk in hospitalized patients with COVID-19 and hemostasis monitoring

scientific article published on 19 June 2020

Prognostic significance of circulating levels of angiogenic cytokines in patients with congestive heart failure

scientific article published on 01 July 2005

Prognostic value of hemoglobin decline over the GRACE score in patients hospitalized for an acute coronary syndrome.

scientific article published on 12 May 2011

Prophylaxis of thromboembolic events during urologic surgery

scientific article published in August 2005

Protein kinase C signaling dysfunction in von Willebrand disease (p.V1316M) type 2B platelets

scientific article published on 01 June 2018

Real-Time Monitoring of von Willebrand Factor in the Catheterization Laboratory: The Seatbelt of Mini-Invasive Transcatheter Aortic Valve Replacement?

scientific article published on 01 September 2018

Relevance of tissue factor in cardiovascular disease

scientific article

Response to letter regarding article, "postprocedural aortic regurgitation in balloon-expandable and self-expandable transcatheter aortic valve replacement procedures: analysis of predictors and impact on long-term mortality: insights from the FRANC

scientific article published on 01 January 2015

Serum hepatocyte growth factor levels predict long-term clinical outcome after percutaneous coronary revascularization.

scientific article published on 16 August 2005

Standardization of extracellular vesicle measurements by flow cytometry through vesicle diameter approximation

scientific article published on 26 April 2018

Standardization of platelet-derived microparticle enumeration by flow cytometry with calibrated beads: results of the International Society on Thrombosis and Haemostasis SSC Collaborative workshop.

scientific article

Surgery and invasive procedures in patients on long-term treatment with direct oral anticoagulants: Thrombin or factor-Xa inhibitors. Recommendations of the Working Group on perioperative haemostasis and the French Study Group on thrombosis and haemo

article

Sustained quality of life improvement after intracoronary injection of autologous bone marrow cells in the setting of acute myocardial infarction: results from the BONAMI trial.

scientific article

TRAnexamic acid in hemorrhagic CESarean section (TRACES) randomized placebo controlled dose-ranging pharmacobiological ancillary trial: study protocol for a randomized controlled trial.

scientific article published in March 2018

The Carmat Bioprosthetic Total Artificial Heart Is Associated With Early Hemostatic Recovery and no Acquired von Willebrand Syndrome in Calves

scientific article published in March 2017

The place of fibrinogen concentrates in the management of perioperative bleeding: A position paper from the Francophone Working Group on Perioperative Haemostasis (GIHP)

scientific article published on 13 April 2018

The presence of apoptotic bone marrow cells impairs the efficacy of cardiac cell therapy

scientific article published on 19 November 2010

The proteome and secretome of human arterial smooth muscle cells

scientific article

Therapeutic and pharmaco-biological, dose-ranging multicentre trial to determine the optimal dose of TRAnexamic acid to reduce blood loss in haemorrhagic CESarean delivery (TRACES): study protocol for a randomised, double-blind, placebo-controlled t

scientific article published in March 2018

Tissue factor pathway inhibitor-2 gene methylation is associated with low expression in carotid atherosclerotic plaques

scientific article published on 19 October 2008

Transducin-like enhancer of split-1 is expressed and functional in human macrophages.

scientific article published on 30 December 2015

Transfusion and postpartum haemorrhage

scientific article published on 10 November 2010

Trauma-induced coagulopathy

scientific article published on 31 July 2013

Treatment of massive bleeding with prothrombin complex concentrate: argument against

scientific article published in December 2010

Two new antithrombin variants support a role for K114 and R13 in heparin binding

scientific article published on 01 February 2003

Updates in the perioperative and emergency management of non-vitamin K antagonist oral anticoagulants

scientific article published on 29 April 2015

Von Willebrand Factor Multimers during Transcatheter Aortic-Valve Replacement

scientific article published in July 2016

Von Willebrand disease: Clinical conundrums

scientific article published on 01 May 2018

[Cell therapy to treat heart failure]

scientific article published on 01 June 2003

[Direct oral anticoagulant associated bleeding].

scientific article

[Hormone replacement therapy and venous thromboembolism]

scientific article

[Management of major bleeding complications and emergency surgery in patients on long-term treatment with direct oral anticoagulants, thrombin or factor-Xa inhibitors. Proposals of the Working Group on Perioperative Haemostasis (GIHP) - March 2013]

scientific article published on 30 August 2013

[Management of massive bleeding in 2013: seven questions and answers]

scientific article published on 12 April 2013

von Willebrand Factor as a Biological Sensor of Blood Flow to Monitor Percutaneous Aortic Valve Interventions

article by Eric Van Belle et al published 27 March 2015 in Circulation Research

von Willebrand Factor for Aortic Valve Intervention: From Bench to Real-Time Bedside Assessment

scientific article published on 01 May 2018

List of works by Sophie Susen

1/1 plasma to red blood cell ratio: an evidence-based practice?

A Laboratory Phenotype/Genotype Correlation of 1167 French Patients From 670 Families With von Willebrand Disease: A New Epidemiologic Picture

A novel ELISA-based diagnosis of acquired von Willebrand disease with increased VWF proteolysis.

Acquired von Willebrand syndrome after continuous-flow mechanical device support contributes to a high prevalence of bleeding during long-term support and at the time of transplantation

Acquired von Willebrand syndrome in aortic stenosis.

Aldosterone, mortality, and acute ischaemic events in coronary artery disease patients outside the setting of acute myocardial infarction or heart failure

Alterations in neutrophil production and function at an early stage in the high-fructose rat model of metabolic syndrome

Ambivalent effect of aortic stenosis on von Willebrand factor and thrombin generation. Is transvalvular gradient the guilty party?

Antibody-Based Protection of von Willebrand Factor Degradation

Antibody-based prevention of von Willebrand factor degradation mediated by circulatory assist devices.

Are there any additional mechanisms for haemolysis in HELLP syndrome?

Arterial Pulsatility and Circulating von Willebrand Factor in Patients on Mechanical Circulatory Support

Atherosclerotic-like process in aortic stenosis: activation of the tissue factor-thrombin pathway and potential role through osteopontin alteration.

Beneficial effects of fenofibrate on plaque thrombogenicity and plaque stability in atherosclerotic rabbits

Bioprosthetic Total Artificial Heart Induces a Profile of Acquired Hemocompatibility With Membranes Recellularization

Blood outgrowth endothelial cells from cord blood and peripheral blood: angiogenesis-related characteristicsin vitro: a rebuttal

CT-ADP Point-of-Care Assay Predicts 30-Day Paravalvular Aortic Regurgitation and Bleeding Events following Transcatheter Aortic Valve Replacement

Circulatory support devices: fundamental aspects and clinical management of bleeding and thrombosis.

Clinical and prognostic implications of low or high level of von Willebrand factor in patients with Waldenstrom macroglobulinemia.

Clinico-Biological Features and Clonal Hematopoiesis in Patients with Severe COVID-19

Coagulation biomarkers are independent predictors of increased oxygen requirements in COVID-19

Comparison of blood activation in the wound, active vent, and cardiopulmonary bypass circuit

Compliance with evidence-based clinical management guidelines in bleeding trauma patients

Decellularized heart valve as a scaffold for in vivo recellularization: deleterious effects of granulocyte colony-stimulating factor.

Detection of monocyte tissue factor after endotoxin stimulation: comparison of one functional and three immunological methods

Dietary CML-enriched protein induces functional arterial aging in a RAGE-dependent manner in mice.

Dietary lipid lowering modifies plaque phenotype in rabbit atheroma after angioplasty: a potential role of tissue factor

Difference in mobilization of progenitor cells after myocardial infarction in smoking versus non-smoking patients: insights from the BONAMI trial.

Drug-eluting stents: trading restenosis for thrombosis?

Dyslipidemia shifts the tissue factor/tissue factor pathway inhibitor balance toward increased thrombogenicity in atherosclerotic plaques

Egfl7 Represses the Vasculogenic Potential of Human Endothelial Progenitor Cells

Endothelial progenitor cells are selectively mobilised immediately after coronary artery bypass grafting or valve surgery

Evaluation of dabigatran, rivaroxaban and apixaban target-specific assays in a multicenter French study.

Evidence for time-dependent activation of monocytes in the systemic circulation in unstable angina but not in acute myocardial infarction or in stable angina

Free leptin, carotid plaque phenotype and relevance to related symptomatology: insights from the OPAL-Lille carotid endarterectomy study

French lyophilized plasma versus fresh frozen plasma for the initial management of trauma-induced coagulopathy: a randomized open-label trial.

Frequency of abdominal aortic aneurysm in patients undergoing coronary artery bypass grafting

From normal to pathological hemostasis.

Functional impairment of von Willebrand factor in hypertrophic cardiomyopathy: relation to rest and exercise obstruction

Gastrointestinal bleeding from angiodysplasia in von Willebrand disease: improved diagnosis and outcome prediction using videocapsule on top of conventional endoscopy

Hemostasis and Thrombosis: Clinical Usefulness of Combined use of Platelet Aggregation Test and Anti PF4-H. Antibodies Elisa test for the Diagnosis of Heparin Induced Thrombocytopenia

High-dose tranexamic acid reduces blood loss in postpartum haemorrhage

High-sensitivity C-reactive protein: potential adjunct for risk stratification in patients with stable congestive heart failure

Human Alternative Macrophages Populate Calcified Areas of Atherosclerotic Lesions and Display Impaired RANKL-Induced Osteoclastic Bone Resorption Activity

Identification of tissue factor in experimental aortic valve sclerosis

Immunomodulatory effect of pentoxifylline during human allograft rejection: involvement of tumor necrosis factor-alpha and adhesion molecules

Impact of initial clinical presentation on clopidogrel low response

In Response

In vivo autologous recellularization of a tissue-engineered heart valve: are bone marrow mesenchymal stem cells the best candidates?

Inflammation triggers colony forming endothelial cell mobilization after angioplasty in chronic lower limb ischemia

Inhibition of tissue factor-factor VIIa proteolytic activity blunts hepatic metastasis in colorectal cancer

Interleukin 8 is differently expressed and modulated by PAR-1 activation in early and late endothelial progenitor cells.

Intracoronary autologous mononucleated bone marrow cell infusion for acute myocardial infarction: results of the randomized multicenter BONAMI trial

Intraoperative cell savage for life-threatening haemorrhagic caesarean section

Intravenous thrombolysis for acute ischaemic stroke in patients on direct oral anticoagulants Expert opinion of the Societe Francaise de Neurologie Vasculaire (SFNV) [French Vascular Neurology Society] and the Groupe Francais d'etudes sur l'Hemostas

Leptin induces osteoblast differentiation of human valvular interstitial cells via the Akt and ERK pathways

Letters to the Editors: letter in response to Bhogal and colleagues

M1 and M2 macrophage proteolytic and angiogenic profile analysis in atherosclerotic patients reveals a distinctive profile in type 2 diabetes

Management Of Antiplatelet Therapy In Patients Undergoing Elective Invasive Procedures Proposals From The French Working Group On Perioperative Hemostasis (Gihp) And The French Study Group On Thrombosis And Hemostasis (Gfht) In Collaboration With Th

Management of Severe Bleeding in Patients Treated with Direct Oral Anticoagulants: An Observational Registry Analysis

Management of antiplatelet therapy in patients undergoing elective invasive procedures: Proposals from the French Working Group on perioperative hemostasis (GIHP) and the French Study Group on thrombosis and hemostasis (GFHT). In collaboration with

Management of bleeding and emergency invasive procedures in patients on dabigatran: Updated guidelines from the French Working Group on Perioperative Haemostasis (GIHP) - September 2016

Management of bleeding and invasive procedures in haemophilia A patients with inhibitor treated with emicizumab (Hemlibra® ): Proposals from the French network on inherited bleeding disorders (MHEMO), the French Reference Centre on Haemophilia, in c

Management of direct oral anticoagulants in patients undergoing elective surgeries and invasive procedures: Updated guidelines from the French Working Group on Perioperative Hemostasis (GIHP) - September 2015.

Management of major bleeding complications and emergency surgery in patients on long-term treatment with direct oral anticoagulants, thrombin or factor-Xa inhibitors: proposals of the working group on perioperative haemostasis (GIHP) - March 2013.

Massive transfusion: assessing higher plasma: blood ratios and earlier plasma administration.

Medical advances in the treatment of postpartum hemorrhage

Meta-Analysis of Abdominal Aortic Aneurysm in Patients With Coronary Artery Disease

Metabolic syndrome and collateral vessel formation in patients with documented occluded coronary arteries: association with hyperglycaemia, insulin-resistance, adiponectin and plasminogen activator inhibitor-1.

Microparticle phenotypes are associated with driver mutations and distinct thrombotic risks in essential thrombocythemia.

Monocyte tissue factor response is decreased in patients with hyperlipidemia

On the versatility of von Willebrand factor

Pentoxifylline prevents upregulation of monocyte tissue factor in renal transplant recipients undergoing post-graft complications

Peripheral arterial revascularization: which antithrombotic agents?

Plasma/platelets/red blood cell ratio in the management of the bleeding traumatized patient: does it matter?

Poor agreement between light transmission aggregometry, Verify Now P2Y₁₂ and vasodilatator-stimulated phosphoprotein for clopidogrel low-response assessment: a potential explanation of negative results of recent randomized trials.

Position of the French Working Group on Perioperative Haemostasis (GIHP) on viscoelastic tests: what role for which indication in bleeding situations?

Postpartum haemorrhage related early increase in D-dimers is inhibited by tranexamic acid: haemostasis parameters of a randomized controlled open labelled trial.

Postprocedural aortic regurgitation in balloon-expandable and self-expandable transcatheter aortic valve replacement procedures: analysis of predictors and impact on long-term mortality: insights from the FRANCE2 Registry.