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List of works by Harm H Kampinga

A PCR amplification strategy for unrestricted generation of chimeric genes.

scientific article published on 27 May 2008

A long-term flow cytometry assay to analyze the role of specific genes of Drosophila melanogaster S2 cells in surviving genotoxic stress

scientific article

Acquisition of thermotolerance induced by heat and arsenite in HeLa S3 cells: multiple pathways to induce tolerance?

scientific article published on February 1, 1992

Alteration of protein folding and degradation in motor neuron diseases: Implications and protective functions of small heat shock proteins.

scientific article published on 29 September 2011

An Image Analysis Technique for Detection of Radiation-induced DNA Fragmentation after CHEF Electrophoresis

scientific article published on 01 August 1993

BAG3 directly interacts with mutated alphaB-crystallin to suppress its aggregation and toxicity

scientific article

BAG3 induces the sequestration of proteasomal clients into cytoplasmic puncta: implications for a proteasome-to-autophagy switch.

scientific article

BRCA1 and BRCA2 heterozygosity and repair of X-ray-induced DNA damage

scientific article published on 01 April 2002

Barcoding heat shock proteins to human diseases: looking beyond the heat shock response

scientific article published on April 2014

Beat shock proteins and atrial fibrillation.

scientific article published on January 2007

Brain death induces renal expression of heme oxygenase-1 and heat shock protein 70.

scientific article published on 29 January 2013

Calpain inhibition prevents pacing-induced cellular remodeling in a HL-1 myocyte model for atrial fibrillation.

scientific article published on June 2004

Cell biological effects of hyperthermia alone or combined with radiation or drugs: a short introduction to newcomers in the field.

scientific article

Cell biology. A cell death avenue evolved from a life-saving path

scientific article published on 01 June 2014

Cells overexpressing Hsp27 show accelerated recovery from heat-induced nuclear protein aggregation.

scientific article published on November 1994

Cellular protein quality control and the evolution of aggregates in spinocerebellar ataxia type 3 (SCA3).

scientific article published in October 2012

Changes in expression of injury after irradiation of increasing volumes in rat lung.

scientific article published in April 2007

Chaperoned by prebiotic inorganic polyphosphate molecules: an ancient transcription-independent mechanism to restore protein homeostasis.

scientific article

Chaperones in Polyglutamine Aggregation: Beyond the Q-Stretch.

scientific article published on 23 March 2017

Chemo- and radiosensitivity testing in a patient with ataxia telangiectasia and Hodgkin disease.

scientific article

Comparison of three rat strains for development of radiation-induced lung injury after hemithoracic irradiation

scientific article published on 01 March 2001

Computational analysis of the human HSPH/HSPA/DNAJ family and cloning of a human HSPH/HSPA/DNAJ expression library

scientific article

Correlation between slowly repairable double-strand breaks and thermal radiosensitization in the human HeLa S3 cell line ⬇️

scientific article published on September 1, 1997

Cytokine treatment improves parenchymal and vascular damage of salivary glands after irradiation

scientific article

Cytotoxicity of artemisinin-related endoperoxides to Ehrlich ascites tumor cells.

scientific article published in June 1993

Cytotoxicity of flavonoids and sesquiterpene lactones from Arnica species against the GLC4 and the COLO 320 cell lines.

scientific article published on October 1994

DNA damage induction and tumour cell radiosensitivity: PFGE and halo measurements ⬇️

scientific article published on 01 May 1998

DNA double strand breaks do not play a role in heat-induced cell killing

scientific article published on 01 November 2005

DNA polymerase activity in heat killing and hyperthermic radiosensitization of mammalian cells as observed after fractionated heat treatments

scientific article published on 01 March 1986

DNAJ proteins and protein aggregation diseases.

scientific article published on January 2012

DNAJB6 is a peptide-binding chaperone which can suppress amyloid fibrillation of polyglutamine peptides at substoichiometric molar ratios.

scientific article published on August 2013

DNAJs: more than substrate delivery to HSPA

scientific article

De novo CoA biosynthesis is required to maintain DNA integrity during development of the Drosophila nervous system.

scientific article published on 10 April 2008

Deficiency of hepatocystin induces autophagy through an mTOR-dependent pathway.

scientific article published in July 2011

Differences in heat-induced cell killing as determined in three mammalian cell lines do not correspond with the extent of heat radiosensitization

scientific article published on 01 October 1986

Different anti-aggregation and pro-degradative functions of the members of the mammalian sHSP family in neurological disorders.

scientific article published on 25 March 2013

Distinguishing aggregate formation and aggregate clearance using cell-based assays

scientific article published on 27 January 2016

Dynamic changes in the localization of thermally unfolded nuclear proteins associated with chaperone-dependent protection

scientific article

Dysfunctional BRCA1 is only indirectly linked to multiple centrosomes.

scientific article

ERCC1, hRad51, and BRCA1 protein expression in relation to tumour response and survival of stage III/IV NSCLC patients treated with chemotherapy

article

Early to late sparing of radiation damage to the parotid gland by adrenergic and muscarinic receptor agonists

scientific article

Effect of hyperthermia on DNA loop-size in HeLa S3 cells.

scientific article published in February 1988

Effects of different small HSPB members on contractile dysfunction and structural changes in a Drosophila melanogaster model for Atrial Fibrillation

scientific article published on 13 July 2011

Elevated mutant dynorphin A causes Purkinje cell loss and motor dysfunction in spinocerebellar ataxia type 23.

scientific article published on 12 July 2015

Enhanced proliferation of acinar and progenitor cells by prophylactic pilocarpine treatment underlies the observed amelioration of radiation injury to parotid glands.

scientific article published on 10 January 2009

Feasibility of measuring radiation-induced DNA double strand breaks and their repair by pulsed field gel electrophoresis in freshly isolated cells from the mouse RIF-1 tumor

scientific article published on 01 August 1996

Function, evolution, and structure of J-domain proteins

scientific article published on 26 November 2018

Functional diversity between HSP70 paralogs due to variable interactions with specific co-chaperones

scientific article published on 13 April 2020

Grp/DChk1 is required for G2-M checkpoint activation in Drosophila S2 cells, whereas Dmnk/DChk2 is dispensable

scientific article published on May 2005

Guidelines for the nomenclature of the human heat shock proteins

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

HSP DNAJB8 controls tumor-initiating ability in renal cancer stem-like cells.

scientific article published on 2 May 2012

HSPA1A-independent suppression of PARK2 C289G protein aggregation by human small heat shock proteins

scientific article

HSPB1, HSPB6, HSPB7 and HSPB8 protect against RhoA GTPase-induced remodeling in tachypaced atrial myocytes

scientific article (publication date: 2011)

HSPB7 is the most potent polyQ aggregation suppressor within the HSPB family of molecular chaperones ⬇️

scientific article published on September 15, 2010

HSPBs: Small proteins with big implications in human disease ⬇️

scientific article published on June 19, 2012

Heat shock protein (Hsp) 40 mutants inhibit Hsp70 in mammalian cells

scientific article (publication date: 17 December 1999)

Heat shock protein 70 (Hsp70) stimulates proliferation and cytolytic activity of natural killer cells

scientific article published in November 1999

Heat shock protein upregulation protects against pacing-induced myolysis in HL-1 atrial myocytes and in human atrial fibrillation

scientific article published on 31 July 2006

Heat shock proteins and Bcl-2 expression and function in relation to the differential hyperthermic sensitivity between leukemic and normal hematopoietic cells

scientific article published on January 2007

Heat shock proteins as potential targets for protective strategies in neurodegeneration

scientific article published on 19 April 2016

Heat-induced intranuclear protein aggregation and thermal radiosensitization

scientific article published on 01 February 1995

Heat-shock treatment selectively affects induction and repair of cyclobutane pyrimidine dimers in transcriptionally active genes in ultraviolet-irradiated human fibroblasts

scientific article published on 01 September 1993

Hsp70 and Hsp40 Chaperone Activities in the Cytoplasm and the Nucleus of Mammalian Cells ⬇️

scientific article published on December 26, 1997

Hsp70 protects mitotic cells against heat-induced centrosome damage and division abnormalities

scientific article published on June 2005

HspB8 participates in protein quality control by a non-chaperone-like mechanism that requires eIF2{alpha} phosphorylation

scientific article published on 29 December 2008

Hydroximic acid derivatives: pleiotropic HSP co-inducers restoring homeostasis and robustness.

scientific article published on January 2013

Hyperthermia, thermotolerance and topoisomerase II inhibitors ⬇️

scientific article published on August 1, 1995

Hyperthermic radiosensitization: mode of action and clinical relevance

scientific article published on 01 April 2001

Identification of the Drosophila ortholog of HSPB8: implication of HSPB8 loss of function in protein folding diseases.

scientific article

In response to Drs. Anscher and Kong

scientific article published on 01 September 2005

Induction of heat shock response protects the heart against atrial fibrillation.

scientific article published on 16 November 2006

Interaction between the cytostatic effects of quercetin and 5-fluorouracil in two human colorectal cancer cell lines

scientific article published on 01 December 1994

Interaction of hyperthermia and radiation in tolerant and nontolerant HeLa S3 cells: role of DNA polymerase inactivation

scientific article published on 01 March 1989

Interaction of the molecular chaperone DNAJB6 with growing amyloid-beta 42 (Aβ42) aggregates leads to sub-stoichiometric inhibition of amyloid formation

scientific article (publication date: 7 November 2014)

Intravital correlated microscopy reveals differential macrophage and microglial dynamics during resolution of neuroinflammation

scientific article

Kadota Fund International Forum 2004. Application of thermal stress for the improvement of health, 15-18 June 2004, Awaji Yumebutai International Conference Center, Awaji Island, Hyogo, Japan. Final report.

scientific article published on March 2008

Keratinocyte growth factor prevents radiation damage to salivary glands by expansion of the stem/progenitor pool

scientific article published on 31 July 2008

Levels of DNAJB family members (HSP40) correlate with disease onset in patients with spinocerebellar ataxia type 3.

scientific article published on 19 August 2010

Loco-regional differences in pulmonary function and density after partial rat lung irradiation.

scientific article published in October 2003

Measurement of Chaperone-Mediated Effects on Polyglutamine Protein Aggregation by the Filter Trap Assay

scientific article published in January 2018

Mechanism of hyperthermic potentiation of cisplatin action in cisplatin-sensitive and -resistant tumour cells.

scientific article published on January 1997

Mobilization of bone marrow stem cells by granulocyte colony-stimulating factor ameliorates radiation-induced damage to salivary glands

scientific article published in March 2006

Modulation of polyglutamine inclusion formation by the Hsp70 chaperone machine.

scientific article published on 8 August 2007

Molecular biology: It takes two to untangle

scientific article published on 05 August 2015

Molecular mechanisms of remodeling in human atrial fibrillation.

scientific article

Molecular mechanisms used by chaperones to reduce the toxicity of aberrant protein oligomers.

scientific article

Mutations in potassium channel kcnd3 cause spinocerebellar ataxia type 19.

scientific article published in December 2012

Optimum dose range for the amelioration of long term radiation-induced hyposalivation using prophylactic pilocarpine treatment.

scientific article published on 19 November 2007

Overexpression of cystathionine γ-lyase suppresses detrimental effects of spinocerebellar ataxia type 3.

scientific article

Overexpression of the cochaperone CHIP enhances Hsp70-dependent folding activity in mammalian cells.

scientific article

Peripheral blood stem cells differ from bone marrow stem cells in cell cycle status, repopulating potential, and sensitivity toward hyperthermic purging in mice mobilized with cyclophosphamide and granulocyte colony-stimulating factor.

scientific article published in June 2002

Polarised asymmetric inheritance of accumulated protein damage in higher eukaryotes

scientific article (publication date: December 2006)

Polyglutamine aggregation in Huntington's disease and spinocerebellar ataxia type 3: similar mechanisms in aggregate formation

scientific article published on 11 June 2015

Post-irradiation dietary vitamin E does not affect the development of radiation-induced lung damage in rats.

scientific article published in July 2004

Preservation of the rat parotid gland function after radiation by prophylactic pilocarpine treatment: radiation dose dependency and compensatory mechanisms

scientific article published on 01 September 1999

Protection of salivary function by concomitant pilocarpine during radiotherapy: a double-blind, randomized, placebo-controlled study

scientific article published on 14 September 2007

Protein refolding in peroxisomes is dependent upon an HSF1-regulated function.

scientific article

Purging of acute myeloid leukaemia cells from stem cell grafts by hyperthermia: enhancement of the therapeutic index by the tetrapeptide AcSDKP and the alkyl-lysophospholipid ET-18-OCH(3)

scientific article published on 01 December 2000

Quantification of transforming growth factor-beta in biological material using cells transfected with a plasminogen activator inhibitor-1 promoter-luciferase construct

scientific article published on 01 April 1997

Radiation and transforming growth factor-beta cooperate in transcriptional activation of the profibrotic plasminogen activator inhibitor-1 gene.

scientific article published on August 2005

Radiation damage to the heart enhances early radiation-induced lung function loss.

scientific article

Radiation induced DNA damage and damage repair in three human tumour cell lines

scientific article published on 01 January 1996

Reconstitution of active telomerase in primary human foreskin fibroblasts: effects on proliferative characteristics and response to ionizing radiation.

scientific article published on May 2004

Reduction of cellular cisplatin resistance by hyperthermia—a review ⬇️

scientific article published on September 1, 1997

Regulation of stress-induced intracellular sorting and chaperone function of Hsp27 (HspB1) in mammalian cells.

scientific article

Relation between radiation-induced whole lung functional loss and regional structural changes in partial irradiated rat lung.

scientific article published in April 2006

Renal expression of heat shock proteins after brain death induction in rats.

scientific article published in January 2005

Repair of UV-induced pyrimidine(6-4)pyrimidone photoproducts is selectively inhibited in transcriptionally active genes after heat treatment of human fibroblasts

scientific article published on 01 May 1995

Rescue of salivary gland function after stem cell transplantation in irradiated glands

scientific article published on 30 April 2008

Rescue of αB Crystallin (HSPB5) Mutants Associated Protein Aggregation by Co-Expression of HSPB5 Partners

scientific article published on 11 May 2015

Resistance to heat radiosensitization and protein damage in thermotolerant and thermoresistant cells

scientific article published on 01 March 1997

RhoA Activation Sensitizes Cells to Proteotoxic Stimuli by Abrogating the HSF1-Dependent Heat Shock Response

scientific article published on 20 July 2015

Role of DNA-PK subunits in radiosensitization by hyperthermia

scientific article published on 01 August 1999

Role of lipid peroxidation and DNA damage in paraquat toxicity and the interaction of paraquat with ionizing radiation

scientific article published on February 18, 1992

SCA14 mutation V138E leads to partly unfolded PKCγ associated with an exposed C-terminus, altered kinetics, phosphorylation and enhanced insolubilization

scientific article published on 13 November 2013

Sensitization to cisplatin action by step-down heating in cDDP-sensitive and -resistant cells.

scientific article published in May 1995

Sensitizing for cis-diamminedichloroplatinum(II) action by hyperthermia in resistant cells

scientific article published on 01 July 1993

Significance of plasma transforming growth factor-beta levels in radiotherapy for non-small-cell lung cancer

scientific article published in April 2004

Small heat shock proteins, protein degradation and protein aggregation diseases.

scientific article published in January 2011

Specific protein homeostatic functions of small heat-shock proteins increase lifespan.

scientific article published on 25 December 2015

Spinocerebellar ataxia type 19/22 mutations alter heterocomplex Kv4.3 channel function and gating in a dominant manner

scientific article

Strand break repair, DNA polymerase activity and heat radiosensitization in thermotolerant cells

scientific article published on 01 April 1985

Stress at the Korean Mountains: meeting report of the 8th International Workshop on the Molecular Biology of Stress Responses ⬇️

scientific article published on October 2, 2010

Structural and functional diversities between members of the human HSPB, HSPH, HSPA, and DNAJ chaperone families.

scientific article published on 17 June 2008

Stwl modifies chromatin compaction and is required to maintain DNA integrity in the presence of perturbed DNA replication.

scientific article published on 03 December 2008

Synergistic action of calcium-ionophores and hyperthermia is best interpreted as thermal enhancement of calcium toxicity

scientific article published on 01 June 1993

The Copper Metabolism MURR1 domain protein 1 (COMMD1) modulates the aggregation of misfolded protein species in a client-specific manner

scientific article

The HSP70 chaperone machinery: J proteins as drivers of functional specificity

scientific article (publication date: August 2010)

The HSPB8-BAG3 chaperone complex is upregulated in astrocytes in the human brain affected by protein aggregation diseases.

scientific article published in February 2012

The N terminus of the small heat shock protein HSPB7 drives its polyQ aggregation-suppressing activity

scientific article published on 16 May 2019

The S/T-Rich Motif in the DNAJB6 Chaperone Delays Polyglutamine Aggregation and the Onset of Disease in a Mouse Model.

scientific article published on 12 April 2016

The growing world of small heat shock proteins: from structure to functions

scientific article published on 31 March 2017

The impact of heart irradiation on dose-volume effects in the rat lung

scientific article published on 01 October 2007

The regulation of the autophagic network and its implications for human disease

scientific article

The small heat shock proteins family: The long forgotten chaperones ⬇️

scientific article published on March 18, 2012

Thermal protein denaturation and protein aggregation in cells made thermotolerant by various chemicals: role of heat shock proteins

scientific article published on 01 August 1995

Thermostability of a nuclear-targeted luciferase expressed in mammalian cells. Destabilizing influence of the intranuclear microenvironment

scientific article published on 01 December 1995

Thermotolerance and nuclear protein aggregation: protection against initial damage or better recovery?

scientific article published on 01 September 1995

Transforming growth factor-beta plasma dynamics and post-irradiation lung injury in lung cancer patients.

scientific article published in May 2004

Versatile members of the DNAJ family show Hsp70 dependent anti-aggregation activity on RING1 mutant parkin C289G.

scientific article

ΔNp73 enhances promoter activity of TGF-β induced genes

scientific article

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