List of works - Jörg Kobarg

"Stop Ne(c)king around": How interactomics contributes to functionally characterize Nek family kinases

scientific article

A draft of the human septin interactome

scientific article

A spectroscopic analysis of the interaction between the human regulatory proteins RACK1 and Ki-1/57

scientific article published on 01 May 2006

A zinc metalloproteinase is responsible for the release of CD30 on human tumor cell lines

scientific article published on 01 November 1995

Analysis of the structural determinants for RNA binding of the human protein AUF1/hnRNP D.

scientific article

Analysis of the tyrosine phosphorylation and calcium fluxing of human CD6 isoforms with different cytoplasmatic domains.

scientific article published in November 1997

Arginine methylation analysis of the splicing-associated SR protein SFRS9/SRP30C.

scientific article

CGI-55 interacts with nuclear proteins and co-localizes to p80-coilin positive-coiled bodies in the nucleus

scientific article (publication date: 2006)

Characterization of a new family of proteins that interact with the C-terminal region of the chromatin-remodeling factor CHD-3

scientific article

Characterization of hNek6 interactome reveals an important role for its short N-terminal domain and colocalization with proteins at the centrosome

scientific article

Characterization of mouse ALCAM (CD166): the CD6-binding domain is conserved in different homologs and mediates cross-species binding

scientific journal article

Characterization of the human NEK7 interactome suggests catalytic and regulatory properties distinct from those of NEK6

scientific article

Characterization, mapping and partial cDNA sequence of the 57-kD intracellular Ki-1 antigen.

scientific article

Checking NEKs: Overcoming a Bottleneck in Human Diseases

scientific article published on 13 April 2020

Crystallization and preliminary X-ray study of β-mannosidase fromTrichoderma reesei

scientific article published on 01 March 2000

Defeating Bacterial Resistance and Preventing Mammalian Cells Toxicity Through Rational Design of Antibiotic-Functionalized Nanoparticles.

scientific article

Detection and possible prognostic relevance of p53 gene mutations in diffuse large B-cell lymphoma. An analysis of 51 cases and review of the literature.

scientific article published in October 2004

Evidence for the association of the human regulatory protein Ki-1/57 with the translational machinery.

scientific article

Expression of deletion mutants of the hepatitis B virus protein HBx in E. coli and characterization of their RNA binding activities.

scientific article published on April 2001

Expression of the NEK family in normal and cancer tissue: an immunohistochemical study

scientific article published on 06 January 2020

FEZ1 interacts with CLASP2 and NEK1 through coiled-coil regions and their cellular colocalization suggests centrosomal functions and regulation by PKC.

scientific article

FEZ2 has acquired additional protein interaction partners relative to FEZ1: functional and evolutionary implications

scientific article

Fasciculation and elongation zeta proteins 1 and 2: From structural flexibility to functional diversity

scientific article published on 01 February 2019

Fasciculation and elongation zeta-1 protein (FEZ1) interacts with the retinoic acid receptor and participates in transcriptional regulation of the Hoxb4 gene

scientific article published on 9 December 2017

From protein interaction profile to functional assignment: the human protein Ki-1/57 is associated with pre-mRNA splicing events

scientific article published on 09 May 2010

Functionalized Silica Nanoparticles As an Alternative Platform for Targeted Drug-Delivery of Water Insoluble Drugs.

scientific article published on March 2016

Genetic analysis of the maternally induced affinity enhancement in the non-Ox1 idiotypic antibody repertoire of the primary immune response to 2-phenyloxazolone.

scientific article published in January 1999

Human FEZ1 has characteristics of a natively unfolded protein and dimerizes in solution

scientific article published on 01 January 2009

Human FEZ1 protein forms a disulfide bond mediated dimer: implications for cargo transport.

scientific article published on September 2010

Human Nek6 is a monomeric mostly globular kinase with an unfolded short N-terminal domain.

scientific article

Human Nek7-interactor RGS2 is required for mitotic spindle organization

scientific article

Human Regulatory Protein Ki-1/57 Is a Target of SUMOylation and Affects PML Nuclear Body Formation.

scientific article

Human hnRNP Q re-localizes to cytoplasmic granules upon PMA, thapsigargin, arsenite and heat-shock treatments

scientific article (publication date: April 2009)

Human stanniocalcin-1 interacts with nuclear and cytoplasmic proteins and acts as a SUMO E3 ligase

scientific article

IIS--Integrated Interactome System: a web-based platform for the annotation, analysis and visualization of protein-metabolite-gene-drug interactions by integrating a variety of data sources and tools

scientific article (publication date: 2014)

Identification and characterization of proteins that selectively interact with isoforms of the mRNA binding protein AUF1 (hnRNP D)

scientific article

Identification of proteins that interact with the central coiled-coil region of the human protein kinase NEK1

scientific article

Insights into the full-length SRPK2 structure and its hydrodynamic behavior

scientific article published on 20 June 2019

Ki-1/57 and CGI-55 ectopic expression impact cellular pathways involved in proliferation and stress response regulation

scientific article published on 7 September 2014

Ki-1/57 interacts with PRMT1 and is a substrate for arginine methylation

scientific article

Kinase inhibitor profile for human nek1, nek6, and nek7 and analysis of the structural basis for inhibitor specificity.

scientific article published on 13 January 2015

Low-resolution structural studies of human Stanniocalcin-1

scientific article

NEK10 interactome and depletion reveal new roles in mitochondria

scientific article published on 28 April 2020

NEK5 interacts with LonP1 and its kinase activity is essential for the regulation of mitochondrial functions and mtDNA maintenance

scientific article published on 24 February 2021

NEK5 interacts with topoisomerase IIβ and is involved in the DNA damage response induced by etoposide

scientific article published on 15 May 2019

Nek5 interacts with mitochondrial proteins and interferes negatively in mitochondrial mediated cell death and respiration.

scientific article published on 26 February 2015

New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing

scientific article

Oncogenic IL7R gain-of-function mutations in childhood T-cell acute lymphoblastic leukemia

scientific article

Over-expression of GFP-FEZ1 causes generation of multi-lobulated nuclei mediated by microtubules in HEK293 cells.

scientific article

Potential Antileukemia Effect and Structural Analyses of SRPK Inhibition by N-(2-(Piperidin-1-yl)-5-(Trifluoromethyl)Phenyl)Isonicotinamide (SRPIN340)

scientific article

Proteomic Analysis of the Spatio-temporal Based Molecular Kinetics of Acute Spinal Cord Injury Identifies a Time- and Segment-specific Window for Effective Tissue Repair

scientific article

Selective synthesis of silver nanoparticles onto potassium hexaniobate: structural organisation with bactericidal properties.

scientific article published on 8 November 2013

Shape Tailored Magnetic Nanorings for Intracellular Hyperthermia Cancer Therapy.

scientific article published in November 2017

Shedding of the soluble form of CD30 from the Hodgkin-analogous cell line L540 is strongly inhibited by a new CD30-specific antibody (Ki-4).

scientific article published on February 1995

Solution structure of the human signaling protein RACK1.

scientific article

Structural analysis of intermolecular interactions in the kinesin adaptor complex fasciculation and elongation protein zeta 1/ short coiled-coil protein (FEZ1/SCOCO)

scientific article

Sweeter but deadlier: decoupling size, charge and capping effects in carbohydrate coated bactericidal silver nanoparticles

scientific article published in November 2013

Tailored silica-antibiotic nanoparticles: overcoming bacterial resistance with low cytotoxicity

scientific article published on 18 June 2014

The CATS (FAM64A) protein is a substrate of the Kinase Interacting Stathmin (KIS).

scientific article

The Drosophila melanogaster Eip74EF-PA transcription factor directly binds the sciarid BhC4-1 promoter

scientific article published on 3 October 2017

The Isoflavanoid (+)‐PTC Regulates Cell‐Cycle Progression and Mitotic Spindle Assembly in a Prostate Cancer Cell Line

scientific article published in 2022

The acidic domain of hnRNPQ (NSAP1) has structural similarity to Barstar and binds to Apobec1

scientific article published on 18 September 2006

The cysteine residues of the hepatitis B virus onco-protein HBx are not required for its interaction with RNA or with human p53.

scientific article

The methylation of the C-terminal region of hnRNPQ (NSAP1) is important for its nuclear localization

scientific article published on 01 July 2006

The molecular motor Myosin Va interacts with the cilia-centrosomal protein RPGRIP1L.

scientific article published on 07 March 2017

Use of a special Brazilian red-light emitting railroad worm Luciferase in bioassays of NEK7 protein Kinase and Creatine Kinase

scientific article published on 19 July 2017

Viral Inhibition Mechanism Mediated by Surface-Modified Silica Nanoparticles.

scientific article published on 10 June 2016

List of works by Jörg Kobarg

"Stop Ne(c)king around": How interactomics contributes to functionally characterize Nek family kinases

A draft of the human septin interactome

A spectroscopic analysis of the interaction between the human regulatory proteins RACK1 and Ki-1/57

A zinc metalloproteinase is responsible for the release of CD30 on human tumor cell lines

Analysis of the structural determinants for RNA binding of the human protein AUF1/hnRNP D.

Analysis of the tyrosine phosphorylation and calcium fluxing of human CD6 isoforms with different cytoplasmatic domains.

Arginine methylation analysis of the splicing-associated SR protein SFRS9/SRP30C.

CGI-55 interacts with nuclear proteins and co-localizes to p80-coilin positive-coiled bodies in the nucleus

Characterization of a new family of proteins that interact with the C-terminal region of the chromatin-remodeling factor CHD-3

Characterization of hNek6 interactome reveals an important role for its short N-terminal domain and colocalization with proteins at the centrosome

Characterization of mouse ALCAM (CD166): the CD6-binding domain is conserved in different homologs and mediates cross-species binding

Characterization of the human NEK7 interactome suggests catalytic and regulatory properties distinct from those of NEK6

Characterization, mapping and partial cDNA sequence of the 57-kD intracellular Ki-1 antigen.

Checking NEKs: Overcoming a Bottleneck in Human Diseases

Crystallization and preliminary X-ray study of β-mannosidase fromTrichoderma reesei

Defeating Bacterial Resistance and Preventing Mammalian Cells Toxicity Through Rational Design of Antibiotic-Functionalized Nanoparticles.

Detection and possible prognostic relevance of p53 gene mutations in diffuse large B-cell lymphoma. An analysis of 51 cases and review of the literature.

Evidence for the association of the human regulatory protein Ki-1/57 with the translational machinery.

Expression of deletion mutants of the hepatitis B virus protein HBx in E. coli and characterization of their RNA binding activities.

Expression of the NEK family in normal and cancer tissue: an immunohistochemical study

FEZ1 interacts with CLASP2 and NEK1 through coiled-coil regions and their cellular colocalization suggests centrosomal functions and regulation by PKC.

FEZ2 has acquired additional protein interaction partners relative to FEZ1: functional and evolutionary implications

Fasciculation and elongation zeta proteins 1 and 2: From structural flexibility to functional diversity

Fasciculation and elongation zeta-1 protein (FEZ1) interacts with the retinoic acid receptor and participates in transcriptional regulation of the Hoxb4 gene

From protein interaction profile to functional assignment: the human protein Ki-1/57 is associated with pre-mRNA splicing events

Functionalized Silica Nanoparticles As an Alternative Platform for Targeted Drug-Delivery of Water Insoluble Drugs.

Genetic analysis of the maternally induced affinity enhancement in the non-Ox1 idiotypic antibody repertoire of the primary immune response to 2-phenyloxazolone.

Human FEZ1 has characteristics of a natively unfolded protein and dimerizes in solution

Human FEZ1 protein forms a disulfide bond mediated dimer: implications for cargo transport.

Human Nek6 is a monomeric mostly globular kinase with an unfolded short N-terminal domain.

Human Nek7-interactor RGS2 is required for mitotic spindle organization

Human Regulatory Protein Ki-1/57 Is a Target of SUMOylation and Affects PML Nuclear Body Formation.

Human hnRNP Q re-localizes to cytoplasmic granules upon PMA, thapsigargin, arsenite and heat-shock treatments

Human stanniocalcin-1 interacts with nuclear and cytoplasmic proteins and acts as a SUMO E3 ligase

IIS--Integrated Interactome System: a web-based platform for the annotation, analysis and visualization of protein-metabolite-gene-drug interactions by integrating a variety of data sources and tools

Identification and characterization of proteins that selectively interact with isoforms of the mRNA binding protein AUF1 (hnRNP D)

Identification of proteins that interact with the central coiled-coil region of the human protein kinase NEK1

Insights into the full-length SRPK2 structure and its hydrodynamic behavior

Ki-1/57 and CGI-55 ectopic expression impact cellular pathways involved in proliferation and stress response regulation

Ki-1/57 interacts with PRMT1 and is a substrate for arginine methylation

Kinase inhibitor profile for human nek1, nek6, and nek7 and analysis of the structural basis for inhibitor specificity.

Low-resolution structural studies of human Stanniocalcin-1

NEK10 interactome and depletion reveal new roles in mitochondria

NEK5 interacts with LonP1 and its kinase activity is essential for the regulation of mitochondrial functions and mtDNA maintenance

NEK5 interacts with topoisomerase IIβ and is involved in the DNA damage response induced by etoposide

Nek5 interacts with mitochondrial proteins and interferes negatively in mitochondrial mediated cell death and respiration.

New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing

Oncogenic IL7R gain-of-function mutations in childhood T-cell acute lymphoblastic leukemia

Over-expression of GFP-FEZ1 causes generation of multi-lobulated nuclei mediated by microtubules in HEK293 cells.

Potential Antileukemia Effect and Structural Analyses of SRPK Inhibition by N-(2-(Piperidin-1-yl)-5-(Trifluoromethyl)Phenyl)Isonicotinamide (SRPIN340)

Proteomic Analysis of the Spatio-temporal Based Molecular Kinetics of Acute Spinal Cord Injury Identifies a Time- and Segment-specific Window for Effective Tissue Repair

Selective synthesis of silver nanoparticles onto potassium hexaniobate: structural organisation with bactericidal properties.

Shape Tailored Magnetic Nanorings for Intracellular Hyperthermia Cancer Therapy.

Shedding of the soluble form of CD30 from the Hodgkin-analogous cell line L540 is strongly inhibited by a new CD30-specific antibody (Ki-4).

Solution structure of the human signaling protein RACK1.

Structural analysis of intermolecular interactions in the kinesin adaptor complex fasciculation and elongation protein zeta 1/ short coiled-coil protein (FEZ1/SCOCO)

Sweeter but deadlier: decoupling size, charge and capping effects in carbohydrate coated bactericidal silver nanoparticles

Tailored silica-antibiotic nanoparticles: overcoming bacterial resistance with low cytotoxicity

The CATS (FAM64A) protein is a substrate of the Kinase Interacting Stathmin (KIS).

The Drosophila melanogaster Eip74EF-PA transcription factor directly binds the sciarid BhC4-1 promoter

The Isoflavanoid (+)‐PTC Regulates Cell‐Cycle Progression and Mitotic Spindle Assembly in a Prostate Cancer Cell Line

The acidic domain of hnRNPQ (NSAP1) has structural similarity to Barstar and binds to Apobec1

The cysteine residues of the hepatitis B virus onco-protein HBx are not required for its interaction with RNA or with human p53.

The methylation of the C-terminal region of hnRNPQ (NSAP1) is important for its nuclear localization

The molecular motor Myosin Va interacts with the cilia-centrosomal protein RPGRIP1L.

Use of a special Brazilian red-light emitting railroad worm Luciferase in bioassays of NEK7 protein Kinase and Creatine Kinase

Viral Inhibition Mechanism Mediated by Surface-Modified Silica Nanoparticles.