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List of works by Chin Wee Tan

A hypermorphic epithelial β-catenin mutation facilitates intestinal tumorigenesis in mice in response to compounding WNT-pathway mutations

scientific article

Analysis of Wnt signaling β-catenin spatial dynamics in HEK293T cells.

scientific article

Analysis of Wnt signalling dynamics during colon crypt development in 3D culture.

scientific article published on 18 June 2015

Colon cryptogenesis: asymmetric budding

scientific article

Colon organoid formation and cryptogenesis are stimulated by growth factors secreted from myofibroblasts.

scientific article published on 21 June 2018

Colonic myofibroblast cell line stimulates colonoid formation.

scientific article published on 30 January 2014

Controlling seepage in discrete particle simulations of biological systems.

scientific article published on 2 December 2015

Discrete Element Framework for Modelling Extracellular Matrix, Deformable Cells and Subcellular Components

scientific article published on 9 October 2015

Imbalance of the renin-angiotensin system may contribute to inflammation and fibrosis in IBD: a novel therapeutic target?

scientific article published on 13 August 2019

LRIG1 extracellular domain: structure and function analysis

scientific article

Loss of Bcl-G, a Bcl-2 family member, augments the development of inflammation-associated colorectal cancer

scientific article published on 11 July 2019

Mathematical model of TGF-βsignalling: feedback coupling is consistent with signal switching.

scientific article

Partial inhibition of gp130-Jak-Stat3 signaling prevents Wnt-β-catenin-mediated intestinal tumor growth and regeneration.

scientific article published on 30 September 2014

Preclinical small molecule WEHI-7326 overcomes drug resistance and elicits response in patient-derived xenograft models of human treatment-refractory tumors

scientific article published on 12 March 2021

Profiling of lung SARS-CoV-2 and influenza virus infection dissects virus-specific host responses and gene signatures

scientific article published on 02 June 2022

Repurposing the selective estrogen receptor modulator to suppress gastrointestinal cancer growth

scientific article published on 01 April 2019

Specification, annotation, visualization and simulation of a large rule-based model for ERBB receptor signaling.

scientific article

TGF-β and IL-6 family signalling crosstalk: an integrated model

scientific article

Transcriptomic profiling of cardiac tissues from <scp>SARS‐CoV</scp>‐2 patients identifies <scp>DNA</scp> damage

scientific article published in 2022

Wnt signalling pathway parameters for mammalian cells

scientific article

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