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List of works by Hui Y Lan

A novel method of microwave treatment for detection of cytoplasmic and nuclear antigens by flow cytometry.

scientific article

A novel, simple, reliable, and sensitive method for multiple immunoenzyme staining: use of microwave oven heating to block antibody crossreactivity and retrieve antigens

scientific article published on 01 January 1995

A simple, reliable, and sensitive method for nonradioactive in situ hybridization: use of microwave heating to improve hybridization efficiency and preserve tissue morphology

scientific article published on 01 March 1996

A small-molecule macrophage migration inhibitory factor antagonist protects against glomerulonephritis in lupus-prone NZB/NZW F1 and MRL/lpr mice.

scientific article

Activation of p53 promotes renal injury in acute aristolochic acid nephropathy

scientific article

Additive renoprotective effects of B2-kinin receptor blocker and PPAR-γ agonist in uninephrectomized db/db mice.

scientific article published on 2 May 2011

Advanced glycation end products activate Smad signaling via TGF-beta-dependent and independent mechanisms: implications for diabetic renal and vascular disease

scientific article published on 22 April 2003

Advanced glycation end-products induce tubular CTGF via TGF-beta-independent Smad3 signaling

scientific article

Amelioration of albuminuria in ROCK1 knockout mice with streptozotocin-induced diabetic kidney disease

scientific article published on 04 October 2011

Angiotensin II up-regulates angiotensin I-converting enzyme (ACE), but down-regulates ACE2 via the AT1-ERK/p38 MAP kinase pathway.

scientific article published on 10 April 2008

Application of microRNAs in diabetes mellitus

scientific article published on 29 April 2014

Asiatic acid inhibits liver fibrosis by blocking TGF-beta/Smad signaling in vivo and in vitro

scientific article

Blockade of NFkappaB activation and renal inflammation by ultrasound-mediated gene transfer of Smad7 in rat remnant kidney.

scientific article

Bone marrow-derived macrophage contributes to fibrosing steatohepatitis through activating hepatic stellate cells

scientific article published on 07 May 2019

Bradykinin and high glucose promote renal tubular inflammation.

scientific article published on 18 November 2009

C-Reactive Protein Promotes Diabetic Kidney Disease in db/db Mice via the CD32b-Smad3-mTOR signaling Pathway.

scientific article published on 25 May 2016

C-reactive protein and ageing.

scientific article

C-reactive protein promotes acute kidney injury by impairing G1/S-dependent tubular epithelium cell regeneration.

scientific article published on May 2014

C-reactive protein promotes acute kidney injury via Smad3-dependent inhibition of CDK2/cyclin E.

scientific article published on 25 July 2016

C-reactive protein promotes acute renal inflammation and fibrosis in unilateral ureteral obstructive nephropathy in mice.

scientific article published on 7 March 2011

C-reactive protein promotes cardiac fibrosis and inflammation in angiotensin II-induced hypertensive cardiac disease.

scientific article published on 15 February 2010

C-reactive protein promotes diabetic kidney disease in a mouse model of type 1 diabetes ⬇️

scientific article published on July 9, 2011

C5a receptor deficiency attenuates T cell function and renal disease in MRLlpr mice.

scientific article

CD44 and hyaluronan expression in the development of experimental crescentic glomerulonephritis

scientific article published on 01 April 1997

CXCL9, but not CXCL10, promotes CXCR3-dependent immune-mediated kidney disease.

scientific article published on 12 March 2008

Calcineurin inhibitors cyclosporin A and tacrolimus protect against podocyte injury induced by puromycin aminonucleoside in rodent models

scientific article published on September 2016

Chaihuang-Yishen granule inhibits diabetic kidney disease in rats through blocking TGF-β/Smad3 signaling.

scientific article

Characteristics of albumin processing during renal passage in anti-Thy1 and anti-glomerular basement membrane glomerulonephritis

scientific article published on 01 March 2000

Chemokines in renal injury.

scientific article published on 07 April 2011

Comparison of free fructose and glucose to sucrose in the ability to cause fatty liver

scientific article

Critical role of macrophage migration inhibitory factor activity in experimental autoimmune diabetes

scientific article published on 24 March 2005

De novo glomerular osteopontin expression in rat crescentic glomerulonephritis

scientific article published on 01 January 1998

Deficiency of Smad7 enhances cardiac remodeling induced by angiotensin II infusion in a mouse model of hypertension

scientific article

Deoxyspergualin suppresses local macrophage proliferation in rat renal allograft rejection

scientific article published on 01 September 1994

Deregulation of E-cadherin-catenin complex in precancerous lesions of gastric adenocarcinoma.

scientific article

Diabetes complications: the microRNA perspective.

scientific article

Dialyzer reuse: interaction between dialyzer membrane, disinfectant (formalin), and blood during dialyzer reprocessing

scientific article published on 01 January 1996

Differential effects of advanced glycation end-products on renal tubular cell inflammation

scientific article published on 01 May 2011

Differential regulation of VEGF by TGF-beta and hypoxia in rat proximal tubular cells.

scientific article published on 8 June 2004

Disruption of Smad4 impairs TGF-β/Smad3 and Smad7 transcriptional regulation during renal inflammation and fibrosis in vivo and in vitro ⬇️

scientific article published on November 2, 2011

Disruption of Smad7 promotes ANG II-mediated renal inflammation and fibrosis via Sp1-TGF-β/Smad3-NF.κB-dependent mechanisms in mice.

scientific article

Diverse roles of TGF-β receptor II in renal fibrosis and inflammation in vivo and in vitro.

scientific article published on 22 February 2012

Dragon (repulsive guidance molecule RGMb) inhibits E-cadherin expression and induces apoptosis in renal tubular epithelial cells.

scientific article published on 19 September 2013

Dual deficiency of angiotensin-converting enzyme-2 and Mas receptor enhances angiotensin II-induced hypertension and hypertensive nephropathy

scientific article published on 24 September 2020

Early differential expression of oncostatin M in obstructive nephropathy

scientific article

Effect of interleukin-10 treatment on crescentic glomerulonephritis in rats.

scientific article published in June 1997

Effects of cyclosporine in osteopontin null mice

scientific article published on 01 July 2002

Elevated Uric Acid Increases Blood Pressure in the Rat by a Novel Crystal-Independent Mechanism ⬇️

scientific article published on November 1, 2001

Elevation of plasma level of macrophage migration inhibitory factor in patients with acute myocardial infarction

scientific article published on 01 October 2001

Enhanced Cancer Immunotherapy with Smad3-Silenced NK-92 Cells

scientific article published on 18 June 2018

Essential role for Smad3 in angiotensin II-induced tubular epithelial-mesenchymal transition.

scientific article published on August 2010

Essential role of Smad3 in angiotensin II-induced vascular fibrosis

scientific article

Evidence for vascular macrophage migration inhibitory factor in destabilization of human atherosclerotic plaques

scientific article published on 01 January 2005

Exosomal miRNA-19b-3p of tubular epithelial cells promotes M1 macrophage activation in kidney injury

scientific article published on 16 May 2019

Expression of human tissue factor pathway inhibitor on vascular smooth muscle cells inhibits secretion of macrophage migration inhibitory factor and attenuates atherosclerosis in ApoE-/- mice

scientific article published on 12 February 2015

Expression of macrophage migration inhibitory factor in human glomerulonephritis

scientific article published on 01 February 2000

Expression profile of macrophage migration-inhibitory factor in human gingiva and reconstituted human gingival epithelia stimulated by Porphyromonas gingivalis lipopolysaccharide.

scientific article published on 9 January 2013

Four-and-a-half LIM protein 2 promotes invasive potential and epithelial-mesenchymal transition in colon cancer.

scientific article

Gene expression profile in colon cancer cells with respect to XIAP expression status.

scientific article published on 13 August 2008

Helicobacter pylori infection is associated with increased expression of macrophage migratory inhibitory factor--by epithelial cells, T cells, and macrophages--in gastric mucosa.

scientific article

Hyperuricemia exacerbates chronic cyclosporine nephropathy.

scientific article

Hyperuricemia induces a primary renal arteriolopathy in rats by a blood pressure-independent mechanism.

scientific article

ICAM-1 directs migration and localization of interstitial leukocytes in experimental glomerulonephritis

scientific article published on 01 January 1994

IL-1 up-regulates osteopontin expression in experimental crescentic glomerulonephritis in the rat.

scientific article published on March 1999

Identification of Genes Associated with Smad3-dependent Renal Injury by RNA-seq-based Transcriptome Analysis.

scientific article

Identification of Smad3-related transcriptomes in type-2 diabetic nephropathy by whole transcriptome RNA sequencing

scientific article published on 25 December 2020

Identification of XAF1 as a novel cell cycle regulator through modulating G(2)/M checkpoint and interaction with checkpoint kinase 1 in gastrointestinal cancer.

scientific article

Identification of novel long noncoding RNAs associated with TGF-β/Smad3-mediated renal inflammation and fibrosis by RNA sequencing.

scientific article

Immunoregulatory activity in adult rat testicular interstitial fluid: relationship with intratesticular CD8+ lymphocytes following treatment with ethane dimethane sulfonate and testosterone implants

scientific article published on 01 April 1998

Impaired TGF-beta signalling enhances peritoneal inflammation induced by E. coli in rats.

scientific article

Inflammatory processes in renal fibrosis.

scientific article published on July 2014

Inhibitory role of Smad7 in hepatocarcinogenesis in mice and in vitro.

scientific article

Initiation and evolution of interstitial leukocytic infiltration in experimental glomerulonephritis.

scientific article published in September 1991

Interleukin 17A promotes hepatocellular carcinoma metastasis via NF-kB induced matrix metalloproteinases 2 and 9 expression.

scientific article

Interleukin-1 receptor antagonist halts the progression of established crescentic glomerulonephritis in the rat

scientific article published on 01 May 1995

Intrarenal metabolomics reveals the association of local organic toxins with the progression of diabetic kidney disease

scientific article published on 17 November 2011

Intrinsic renal cells are the major source of interleukin-1 beta synthesis in normal and diseased rat kidney

scientific article published on 01 June 1997

Kallistatin protects against diabetic nephropathy in db/db mice by suppressing AGE-RAGE-induced oxidative stress.

scientific article published on 4 November 2015

Kidney-targeting Smad7 gene transfer inhibits renal TGF-β/MAD homologue (SMAD) and nuclear factor κB (NF-κB) signalling pathways, and improves diabetic nephropathy in mice ⬇️

scientific article published on November 16, 2011

LRNA9884, a Novel Smad3-Dependent Long Noncoding RNA, Promotes Diabetic Kidney Injury in db/db Mice via Enhancing MCP-1-Dependent Renal Inflammation

scientific article published on 02 May 2019

Latent Transforming Growth Factor-β1 Protects against Bleomycin-Induced Lung Injury in Mice

scientific article published on 01 December 2014

Leukocyte populations of the adult rat testis following removal of the Leydig cells by treatment with ethane dimethane sulfonate and subcutaneous testosterone implants.

scientific article

Local macrophage and myofibroblast proliferation in progressive renal injury in the rat remnant kidney

scientific article published on 01 August 1998

Local macrophage proliferation in human glomerulonephritis ⬇️

scientific article published on July 1, 1998

Local macrophage proliferation in the progression of glomerular and tubulointerstitial injury in rat anti-GBM glomerulonephritis

scientific article published on 01 September 1995

Local regulation of macrophage subsets in the adult rat testis: examination of the roles of the seminiferous tubules, testosterone, and macrophage-migration inhibitory factor.

scientific article

Long Noncoding RNA Arid2-IR Is a Novel Therapeutic Target for Renal Inflammation

scientific article published on 6 March 2015

Loss of XIAP sensitizes colon cancer cells to PPARgamma independent antitumor effects of troglitazone and 15-PGJ2.

scientific article published on 13 May 2008

Loss of angiotensin-converting enzyme 2 enhances TGF-β/Smad-mediated renal fibrosis and NF-κB-driven renal inflammation in a mouse model of obstructive nephropathy

article

Loss of miR-29 in myoblasts contributes to dystrophic muscle pathogenesis

scientific article published on 20 March 2012

Macrophage migration inhibitory factor (MIF)--potential perspectives for immune-intervention in renal disease

scientific article published on 01 November 1998

Macrophage migration inhibitory factor expression correlates with inflammatory changes in human chronic hepatitis B infection.

scientific article published in June 2005

Macrophage migration inhibitory factor expression in human renal allograft rejection

scientific article published on 01 December 1998

Macrophage migration inhibitory factor expression in male and female ethanol-fed rats.

scientific article published in December 2001

Macrophage migration inhibitory factor induces MMP-9 expression in macrophages via the MEK-ERK MAP kinase pathway.

scientific article published on February 2007

Macrophage migration inhibitory factor induces MMP-9 expression: implications for destabilization of human atherosclerotic plaques

scientific article published on 01 January 2005

Macrophage migratory inhibitory factor (MIF) expression in acute graft-versus-host disease (GVHD) in allogeneic hemopoietic stem cell transplant recipients

scientific article published on 01 September 2002

Macrophages promote renal fibrosis through direct and indirect mechanisms

scientific article

Mechanism of chronic aristolochic acid nephropathy: role of Smad3.

scientific article

Mice overexpressing latent TGF-beta1 are protected against renal fibrosis in obstructive kidney disease

scientific article published on 30 April 2008

MicroRNA-29b inhibits diabetic nephropathy in db/db mice

scientific article

MicroRNA-29b inhibits peritoneal fibrosis in a mouse model of peritoneal dialysis

scientific article published on 21 July 2014

MicroRNAs in Diabetic Kidney Disease

scientific article

MicroRNAs in renal fibrosis

scientific article

N-Acetyl-seryl-aspartyl-lysyl-proline Alleviates Renal Fibrosis Induced by Unilateral Ureteric Obstruction in BALB/C Mice.

scientific article

Novel lncRNA Erbb4-IR Promotes Diabetic Kidney Injury in db/db Mice by Targeting miR-29b.

scientific article published on 8 December 2017

Oncogene functions of FHL2 are independent from NF-kappaBIalpha in gastrointestinal cancer

scientific article published on 28 August 2008

Opposing roles for Smad2 and Smad3 in peritoneal fibrosis in vivo and in vitro

scientific article published on 10 June 2014

Osteopontin expression in progressive renal injury in remnant kidney: role of angiotensin II

scientific article published on 01 October 2000

Pancreatic duodenal homeobox-1 (PDX1) functions as a tumor suppressor in gastric cancer.

scientific article

Partial loss of Smad7 function impairs bone remodeling, osteogenesis and enhances osteoclastogenesis in mice

scientific article published on 03 July 2014

Peroxisome proliferator-activated receptor-gamma contributes to the inhibitory effects of Embelin on colon carcinogenesis.

scientific article

Polymeric IgA increases the synthesis of macrophage migration inhibitory factor by human mesangial cells in IgA nephropathy

scientific article published on 01 January 2003

Renal inflammation is modulated by potassium in chronic kidney disease: possible role of Smad7

scientific article published on 18 July 2007

Renoprotection by rosiglitazone in accelerated type 2 diabetic nephropathy: Role of STAT1 inhibition and nephrin restoration.

scientific article published on July 2010

Renoprotective effect of berberine on type 2 diabetic nephropathy in rats

scientific article published on 01 June 2015

Ribosomal protein S19 is a novel therapeutic agent in inflammatory kidney disease.

scientific article published in May 2013

Role for macrophage migration inhibitory factor in acute respiratory distress syndrome.

scientific article published in April 2003

Role of ERK1/2 and p38 mitogen-activated protein kinases in the regulation of thrombospondin-1 by TGF-beta1 in rat proximal tubular cells and mouse fibroblasts.

scientific article published on 16 February 2005

Role of JAK/STAT pathway in IL-6-induced activation of vascular smooth muscle cells

scientific journal article

Role of NAD(P)H oxidase in transforming growth factor-beta1-induced monocyte chemoattractant protein-1 and interleukin-6 expression in rat renal tubular epithelial cells.

scientific article published on 3 February 2009

Role of TGF-beta signaling in extracellular matrix production under high glucose conditions.

scientific article published on June 2003

Role of macrophage migration inhibition factor in kidney disease

scientific article published on 25 July 2008

Role of the TGF-β/BMP-7/Smad pathways in renal diseases

scientific article

SMAD3 promotes autophagy dysregulation by triggering lysosome depletion in tubular epithelial cells in diabetic nephropathy

scientific article published on 12 October 2020

Signaling mechanism of renal fibrosis in unilateral ureteral obstructive kidney disease in ROCK1 knockout mice

scientific article published on 27 September 2006

Smad2 protects against TGF-beta/Smad3-mediated renal fibrosis.

scientific article

Smad3 mediates ANG II-induced hypertensive kidney disease in mice ⬇️

scientific article published on January 11, 2012

Smad3 mediates cardiac inflammation and fibrosis in angiotensin II-induced hypertensive cardiac remodeling

scientific article published on 15 March 2010

Smad7 as a therapeutic agent for chronic kidney diseases.

scientific article published on May 2008

Smad7 gene therapy ameliorates an autoimmune crescentic glomerulonephritis in mice.

scientific article published on 2 May 2007

Smad7 gene transfer attenuates angiogenesis in peritoneal dialysis rats

scientific article published on 01 February 2013

Smad7 gene transfer inhibits peritoneal fibrosis

scientific article published on 12 September 2007

Smad7 inhibits AngII-mediated hypertensive nephropathy in a mouse model of hypertension

scientific article published on 01 August 2014

Smad7 inhibits angiotensin II-induced hypertensive cardiac remodelling.

scientific article published on 12 June 2013

Smad7 suppresses renal fibrosis via altering expression of TGF-β/Smad3-regulated microRNAs

scientific article published on 4 December 2012

Smad7 transgene attenuates peritoneal fibrosis in uremic rats treated with peritoneal dialysis

scientific article published on 12 September 2007

Stanniocalcin-1 regulates endothelial gene expression and modulates transendothelial migration of leukocytes

scientific article

Suppression of experimental crescentic glomerulonephritis by the interleukin-1 receptor antagonist

scientific article published on 01 February 1993

Suppression of malignancy by Smad3 in mouse embryonic stem cell formed teratoma ⬇️

scientific article published on October 1, 2013

TGF-β in renal fibrosis: triumphs and challenges

scientific article published on 01 April 2020

TGF-β/Smad signaling in kidney disease.

scientific article published on May 2012

TGF-β/Smad signaling in renal fibrosis

scientific article

TGF-β/Smad3 signaling promotes renal fibrosis by inhibiting miR-29

scientific article

TGF-β: the master regulator of fibrosis

scientific article published on 25 April 2016

The Emerging Role of Innate Immunity in Chronic Kidney Diseases

scientific article published on 04 June 2020

The ICAM-1/LFA-1 interaction in glomerular leukocytic accumulation in anti-GBM glomerulonephritis.

scientific article

The Mincle/Syk/NF-κB Signalling Circuit is Essential for Maintaining the Protumoral Activities of Tumor-associated Macrophages

scientific article published on 12 June 2020

The decreased expression of electron transfer flavoprotein β is associated with tubular cell apoptosis in diabetic nephropathy

scientific article published on 18 March 2016

The protective role of Smad7 in diabetic kidney disease: mechanism and therapeutic potential

scientific article

Therapeutic Effects of Tangshen Formula on Diabetic Nephropathy in Rats

scientific article published on 25 January 2016

Therapeutic effects of cytokine blockade in glomerulonephritis ⬇️

scientific article published on 01 January 1998

Tissue kallikrein mediates pro-inflammatory pathways and activation of protease-activated receptor-4 in proximal tubular epithelial cells

scientific article

Transferrin but not albumin mediates stimulation of complement C3 biosynthesis in human proximal tubular epithelial cells

scientific article published on 01 January 2001

Transforming Growth Factor-β: A Multifunctional Regulator of Cancer Immunity

scientific article published on 23 October 2020

Transforming growth factor beta1 promotes chromosomal instability in human papillomavirus 16 E6E7-infected cervical epithelial cells.

scientific article

Transforming growth factor-beta and Smad signalling in kidney diseases.

scientific article

Transforming growth factor-beta regulates tubular epithelial-myofibroblast transdifferentiation in vitro

scientific journal article

Transforming growth factor-β signalling in renal fibrosis: from Smads to non-coding RNAs

scientific article published on 28 June 2018

Transforming growth factor-β/Smad signalling in diabetic nephropathy.

scientific article published on August 2012

Transforming growth factor-β1 mediates psoriasis-like lesions via a Smad3-dependent mechanism in mice.

scientific article

Treatment of established peritoneal fibrosis by gene transfer of Smad7 in a rat model of peritoneal dialysis.

scientific article

Tubular epithelial-myofibroblast transdifferentiation in progressive tubulointerstitial fibrosis in 5/6 nephrectomized rats.

scientific article published on September 1998

Tubular phenotypic change in progressive tubulointerstitial fibrosis in human glomerulonephritis.

scientific article published on October 2001

Tubule-Specific Mst1/2 Deficiency Induces CKD via YAP and Non-YAP Mechanisms

scientific article published on 06 April 2020

Tubules are the major site of M-CSF production in experimental kidney disease: correlation with local macrophage proliferation

scientific article published on 01 August 2001

Ultrasound-contrast agent mediated naked gene delivery in the peritoneal cavity of adult rat.

scientific article published on 25 October 2007

Ultrasound-microbubble-mediated gene transfer of inducible Smad7 blocks transforming growth factor-beta signaling and fibrosis in rat remnant kidney.

scientific article published on March 2005

Up-regulation of macrophage colony-stimulating factor (M-CSF) and migration inhibitory factor (MIF) expression and monocyte recruitment during lipid-induced glomerular injury in the exogenous hypercholesterolaemic (ExHC) rat

scientific article published on 01 May 1997

Up-regulation of macrophage migration inhibitory factor in infants with acute neonatal necrotizing enterocolitis.

scientific article published in June 2005

Upregulation of Angiotensin (1-7)-Mediated Signaling Preserves Endothelial Function Through Reducing Oxidative Stress in Diabetes.

scientific article

Uric acid stimulates monocyte chemoattractant protein-1 production in vascular smooth muscle cells via mitogen-activated protein kinase and cyclooxygenase-2.

scientific article published on 12 May 2003

Validity of leptin receptor-deficiency (db/db) type 2 diabetes mellitus mice as a model of secondary osteoporosis

scientific article published on 10 June 2016

XIAP-associated factor 1 (XAF1) suppresses angiogenesis in mouse endothelial cells.

scientific article

c-Jun N-terminal kinase (JNK1) upregulates XIAP-associated factor 1 (XAF1) through interferon regulatory factor 1 (IRF-1) in gastrointestinal cancer.

scientific article

miR-21 is a key therapeutic target for renal injury in a mouse model of type 2 diabetes.

scientific article

miR-29 inhibits bleomycin-induced pulmonary fibrosis in mice.

scientific article

miR-29b as a therapeutic agent for angiotensin II-induced cardiac fibrosis by targeting TGF-β/Smad3 signaling

scientific article published on 26 February 2014

miR-30a Negatively Regulates TGF-β1–Induced Epithelial-Mesenchymal Transition and Peritoneal Fibrosis by Targeting Snai1 ⬇️

scientific article published on July 3, 2013

miRNA-29b improves bone healing in mouse fracture model.

scientific article published on 22 April 2016

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