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List of works by Alejandro Madrigal

16th IHIW: International Histocompatibility Working Group in Hematopoietic Cell Transplantation ⬇️

scientific article published on December 28, 2012

A comparison of viral microneutralization and haemagglutination inhibition assays as measures of seasonal inactivated influenza vaccine immunogenicity in the first year after reduced intensity conditioning, lymphocyte depleted allogeneic haematopoie

scientific article published on 13 December 2018

A donor-specific epigenetic classifier for acute graft-versus-host disease severity in hematopoietic stem cell transplantation

scientific article

A matter of identity - Phenotype and differentiation potential of human somatic stem cells.

scientific article published on 25 April 2015

A novel HLA-A allele, A*74:23, identified in an individual from Costa Rica

scientific article published on 27 October 2014

A novel HLA-DPB1 allele, DPB1*125:01, identified by sequence-based typing in an Indian individual.

scientific article published on 30 September 2010

A quantitative assay for Epstein-Barr Virus-specific immunity shows interferon-gamma producing CD8+ T cells increase during immunosuppression reduction to treat posttransplant lymphoproliferative disease.

scientific article

A review of the haematopoietic stem cell donation experience: is there room for improvement?

scientific article published on 27 January 2014

Allogeneic T cells: maestro in the co-ordination of the immune response after hematopoietic stem cell transplantation.

scientific article published on February 2014

Allogeneic and autologous transplantation for haematological diseases, solid tumours and immune disorders: definitions and current practice in Europe.

scientific article published in March 2006

Allogeneic hematopoietic stem cell donation-standardized assessment of donor outcome data: a consensus statement from the Worldwide Network for Blood and Marrow Transplantation (WBMT).

scientific article

An overview of HLA typing for hematopoietic stem cell transplantation

scientific article published on 01 January 2014

An update on graft-versus-host and graft-versus-leukemia reactions: a summary of the sixth International Symposium held in Schloss Ellmau, Germany, January 22-24, 2004

scientific article published on 01 November 2004

Assessing the toxic effects of DMSO on cord blood to determine exposure time limits and the optimum concentration for cryopreservation.

scientific article

Avoiding room temperature storage and delayed cryopreservation provide better postthaw potency in hematopoietic progenitor cell grafts.

scientific article published on 11 December 2012

B cell regulation in cancer and anti-tumor immunity.

scientific article

Caspase-8 polymorphisms result in reduced Alemtuzumab-induced T-cell apoptosis and worse survival after transplantation

scientific article published on 27 October 2014

Challenges and opportunities for HSCT outcome registries: perspective from international HSCT registries experts

scientific article published on 28 April 2014

Characterization of 5' promoter and exon 1-3 polymorphism of the RAET1E gene.

scientific article published on 28 October 2015

Clinical Grade Regulatory CD4+ T Cells (Tregs): Moving Toward Cellular-Based Immunomodulatory Therapies.

scientific article published on 13 February 2018

Clinical importance of HLA-DPB1 in haematopoietic cell transplantation

scientific article published on 01 April 2007

Cloning and sequencing full-length HLA-B and -C genes.

scientific article

Complete cDNA sequences of the HLA-DRB1*0402 and DRB1*11041 alleles.

scientific article published in October 2002

Cord blood Lin(-)CD45(-) embryonic-like stem cells are a heterogeneous population that lack self-renewal capacity

scientific article published on 28 June 2013

Cord blood serum affects T cells ability to produce and respond to IL-2.

scientific article published on April 2003

Cord blood transplants: early recovery of neutrophils from co-transplanted sibling haploidentical progenitor cells and lack of engraftment of cultured cord blood cells, as ascertained by analysis of DNA polymorphisms

scientific article published on 01 August 2001

Cytomegalovirus-specific CD8+ T cells targeting different peptide/HLA combinations demonstrate varying T-cell receptor diversity

scientific article published on 01 January 2012

Cytomegalovirus‐Specific Cellular Immune Responses and Viremia in Recipients of Allogeneic Stem Cell Transplants

article

Detection of vimentin-specific autoreactive CD8+ T cells in cardiac transplant patients.

scientific article published in May 2004

Differential activation of cord blood and peripheral blood natural killer cells by cytokines

scientific article published on 22 September 2014

Differential effects of mycophenolate mofetil and cyclosporine A on peripheral blood and cord blood natural killer cells activated with interleukin-2.

scientific article

Differential pathways govern CD4+ CD28- T cell proinflammatory and effector responses in patients with coronary artery disease

scientific article published on 01 October 2008

Diverging effects of HLA-DPB1 matching status on outcome following unrelated donor transplantation depending on disease stage and the degree of matching for other HLA alleles.

scientific article published on 19 November 2009

Diversity and characterisation of polymorphic 3' untranslated region haplotypes of MICA and MICB genes

scientific article published on 01 December 2018

Diversity and characterization of polymorphic 5' promoter haplotypes of MICA and MICB genes

scientific article

Ethnicity, length of time on the register and sex predict donor availability at the confirmatory typing stage.

scientific article published on 13 January 2014

Exploiting beneficial alloreactive T cells.

scientific article

Expression levels of MHC class I molecules are inversely correlated with promiscuity of peptide binding

scientific article published on 10 April 2015

Factors affecting reconstitution of the T cell compartment in allogeneic haematopoietic cell transplant recipients.

scientific article published on November 2003

Factors modulating circulation of hematopoietic progenitor cells in cord blood and neonates.

scientific article published in January 2009

Female donors and donors who are lighter than their recipient are less likely to meet the CD34+ cell dose requested for peripheral blood stem cell transplantation.

scientific article published on 27 May 2014

Flow cytometry assessment of apoptotic CD34+ cells by annexin V labeling may improve prediction of cord blood potency for engraftment

scientific article published on 24 August 2011

Frozen cord blood hematopoietic stem cells differentiate into higher numbers of functional natural killer cells in vitro than mobilized hematopoietic stem cells or freshly isolated cord blood hematopoietic stem cells

scientific article published on 29 January 2014

Functional impairment of human T-lymphocytes following PHA-induced expansion and retroviral transduction: implications for gene therapy.

scientific article published in October 2002

Further diversity at HLA-A and -B loci identified in Afro-Caribbean potential bone marrow donors.

scientific article published in January 2001

Further diversity of the 5' promoter region of the MHC class I-related chain B gene

scientific article published on 28 December 2015

Further polymorphism of the MICA gene.

scientific article published in February 2002

Further polymorphism of the RAET1E/ULBP4 gene in humans.

scientific article published on 22 May 2014

Generation of natural killer cells from hematopoietic stem cells in vitro for immunotherapy

scientific article published on 18 June 2012

Genomic sequence of the rare HLA-A*02:95 allele identified by sequence-based typing and cloning

scientific article published on 20 June 2014

HLA Typing for the Next Generation

scientific article published on 27 May 2015

HLA class I diversity in Kolla Amerindians.

scientific article published on February 2001

HLA class I mono-specific APCs and target cells: a method to standardise in vitro CD8+ T cell expansion and functional assays

scientific article published on 05 July 2006

HLA mismatches and hematopoietic cell transplantation: structural simulations assess the impact of changes in peptide binding specificity on transplant outcome.

scientific article published on January 2011

HLA tetramers and anti-CMV immune responses: from epitope to immunotherapy

scientific article published on 01 January 2002

HLA-A, -B, -C, -DQB1, and -DRB1,3,4,5 allele and haplotype frequencies in the Costa Rica Central Valley Population and its relationship to worldwide populations.

scientific article

HLA-A3 increases and HLA-DR1 decreases the risk of acute graft-versus-host disease after HLA-matched sibling bone marrow transplantation for chronic myelogenous leukaemia

scientific article published on 01 July 2001

HLA-B typing by reference strand mediated conformation analysis using a capillary-based semiautomated genetic analyzer

scientific article published on 01 April 2001

HLA-DPB1 matching status has significant implications for recipients of unrelated donor stem cell transplants

scientific article published on 18 October 2005

HLA-DRB1*03:49, a novel allele identified by group-specific sequence-based typing in a North European individual

scientific article published in November 2013

Harvests from bone marrow donors who weigh less than their recipients are associated with a significantly increased probability of a suboptimal harvest yield.

scientific article

Heat-shock protein 60-reactive CD4+CD28null T cells in patients with acute coronary syndromes.

scientific article published on March 2004

Hematopoietic SCT in Europe: data and trends in 2011.

scientific article

Hematopoietic SCT in Europe: data and trends in 2012 with special consideration of pediatric transplantation

scientific article

High-resolution HLA allele and haplotype frequencies in majority and minority populations of Costa Rica and Nicaragua: differential admixture proportions in neighboring countries.

scientific article published on 23 April 2018

Human KIR sequences 2003.

scientific article published on 28 June 2003

Hurdles in therapy with regulatory T cells

scientific article published on September 2015

Identification and nucleotide sequence of a new null allele, HLA B*3540N

scientific article published on 01 June 2002

Identification of HLA-A*2306.

scientific article

Identification of HLA-B*1566.

scientific article published in May 2002

Identification of a novel KIR3DL1*072 allele by sequence-based typing

scientific article published in February 2010

Identification of medically important pathogenic fungi by reference strand-mediated conformational analysis (RSCA).

scientific article

Identification of non-naïve CD4+CD45RA+ T cell subsets in adult allogeneic haematopoietic cell transplant recipients

scientific article published on 01 September 2003

Immunogenetic factors in donors and patients that affect the outcome of hematopoietic stem cell transplantation

scientific article published on 25 October 2007

Immunoglobulin heavy-chain gene rearrangement in adult acute lymphoblastic leukemia reveals preferential usage of J(H)-proximal variable gene segments

scientific article published on 01 May 2001

Immunotherapy after hematopoietic stem cell transplantation using umbilical cord blood-derived products

scientific article

Indications for allo- and auto-SCT for haematological diseases, solid tumours and immune disorders: current practice in Europe, 2015.

scientific article published on 23 March 2015

Individual quality assessment of autografting by probability estimation for clinical endpoints: a prospective validation study from the European group for blood and marrow transplantation.

scientific article

Interaction between natural killer cells and regulatory T cells: perspectives for immunotherapy

scientific article

Investigation of peptide involvement in T cell allorecognition using recombinant HLA class I multimers.

scientific article published on August 2005

KIR gene in ethnic and Mestizo populations from Mexico

scientific article published on 01 January 2006

Linkage of Patr-AL to Patr-A and- B in the major histocompatibility complex of the common chimpanzee (Pan troglodytes).

scientific article published on 11 April 2002

MHC typing in variant Creutzfeldt-Jakob disease.

scientific article published on February 2003

MHC-class-II are expressed in a subpopulation of human neural stem cells in vitro in an IFNγ-independent fashion and during development.

scientific article

MICA sequences 2000.

scientific article published in March 2001

Major histocompatibility complex class I-related chain A allele mismatching, antibodies, and rejection in renal transplantation

scientific article published on 24 May 2011

Methods for Functional Analysis of Stem Cells

scientific article published on 01 January 2014

Methods of detection of immune reconstitution and T regulatory cells by flow cytometry

scientific article published on January 2014

Multiple unit pooled umbilical cord blood is a viable source of therapeutic regulatory T cells.

scientific article published on January 2013

Natural Killer Cell Immunotherapy: From Bench to Bedside

scientific article published on 03 June 2015

Natural Killer Cells Improve Hematopoietic Stem Cell Engraftment by Increasing Stem Cell Clonogenicity In Vitro and in a Humanized Mouse Model.

scientific article published on 14 October 2015

Natural killer cells differentiated in vitro from cord blood CD34+ cells are more advantageous for use as an immunotherapy than peripheral blood and cord blood natural killer cells

scientific article published on 17 April 2017

No impact of NOD2/CARD15 on outcome after SCT: a reply

scientific article published on 11 August 2008

Novel alleles of the transforming growth factor β-1 regulatory region and exon 1.

scientific article

Predonation health-related quality of life scores predict time to recovery in hematopoietic stem cell donors.

scientific article published on 4 November 2014

Progress made towards the development of a CMV peptide vaccine.

scientific article published on May 2004

Prophylaxis and treatment of GVHD: EBMT-ELN working group recommendations for a standardized practice.

scientific article published on 29 July 2013

Quantitative and qualitative differences in use and trends of hematopoietic stem cell transplantation: a Global Observational Study.

scientific article published on 18 March 2013

RAET1/ULBP alleles and haplotypes among Kolla South American Indians

scientific article published on 13 February 2013

Recipient/donor HLA and CMV matching in recipients of T-cell-depleted unrelated donor haematopoietic cell transplants

scientific article published on 16 January 2017

Recommendations for a standard UK approach to incorporating umbilical cord blood into clinical transplantation practice: conditioning protocols and donor selection algorithms.

scientific article published on 12 January 2009

Regulatory T cells inhibit CD34+ cell differentiation into NK cells by blocking their proliferation.

scientific article published on 26 February 2016

Routine vaccination practice after adult and paediatric allogeneic haematopoietic stem cell transplant: a survey of UK NHS programmes

scientific article

Sequence of a novel HLA-A*0301 intronic variant (A*03010103)

scientific article published on 01 January 2005

Severe allergic reaction with anaphylaxis to G-CSF (lenograstim) in a healthy donor

scientific article published on 19 January 2009

Short tandem repeat (STR) haplotypes in HLA: an integrated 50-kb STR/linkage disequilibrium/gene map between the RING3 and HLA-B genes and identification of STR haplotype diversification in the class III region

scientific article published on 01 August 2001

Single molecule real-time DNA sequencing of HLA genes at ultra-high resolution from 126 International HLA and Immunogenetics Workshop cell lines.

scientific article published on 24 November 2017

Single nucleotide polymorphisms in the NOD2/CARD15 gene are associated with an increased risk of relapse and death for patients with acute leukemia after hematopoietic stem-cell transplantation with unrelated donors.

scientific article published on 27 August 2007

Sociodemographic and psychological determinants of influenza vaccine intention among recipients of autologous and allogeneic haematopoietic stem cell transplant: a cross-sectional survey of UK transplant recipients using a modified health belief mode

article

Subsequent donation requests among 2472 unrelated hematopoietic progenitor cell donors are associated with bone marrow harvest ⬇️

scientific article published on June 28, 2013

Ten years after the first inspection of a candidate European centre, an EBMT registry analysis suggests that clinical outcome is improved when hematopoietic SCT is performed in a JACIE accredited program

scientific article published on 07 March 2011

The EBMT activity survey: 1990-2010

scientific article

The European searchable tumour line database.

scientific article published on 27 January 2009

The degree of matching at HLA-DPB1 predicts for acute graft-versus-host disease and disease relapse following haematopoietic stem cell transplantation.

scientific article published in June 2003

The effect of cord blood sera on CD69 expression

scientific article published on 01 October 2002

The effect of interleukin-7 on the alloreactivity of human T cells depends on the timing of its administration in relation to the allostimulus

scientific article published on 01 April 2005

The effects of CAMPATH-1H on cell viability do not correlate to the CD52 density on the cell surface

scientific article

The impact of HLA genotyping on survival following unrelated donor haematopoietic stem cell transplantation.

scientific article published on 15 June 2010

The impact of improved JACIE standards on the care of related BM and PBSC donors

scientific article published on 10 November 2014

The importance of HLA-DPB1 in unrelated donor hematopoietic cell transplantation

scientific article published on 28 August 2007

The novel HLA-B*44 allele, HLA-B*44:220, identified by Single Molecule Real-Time DNA sequencing in a British Caucasoid male.

scientific article published on 5 June 2015

The role of Vδ2-negative γδ T cells during cytomegalovirus reactivation in recipients of allogeneic stem cell transplantation

scientific article published on 24 June 2010

The unique profile of cord blood natural killer cells balances incomplete maturation and effective killing function upon activation

scientific article published on 28 December 2011

The use of granulocyte-colony-stimulating factor in volunteer unrelated hemopoietic stem cell donors.

scientific article published on 28 March 2008

Three novel allelic variants of the RAET1E/ULBP4 gene in humans.

scientific article

Topical issues in unrelated donor haematopoietic stem cell transplants: a report from a workshop convened by the Anthony Nolan Trust in London - 2005.

scientific article

Transcription factors involved in the regulation of natural killer cell development and function: an update ⬇️

scientific article published on October 15, 2012

Two novel 5' promoter sequences of the MHC class I-related chain A gene.

scientific article published on 25 March 2015

Two novel MICA alleles, MICA*054 and MICA*056.

scientific article

Two sets of HLA Class II DRB and DQB1 alleles co-segregate among family members in a single maternal haplotype.

scientific article

UCB transplant supported by the co-infusion of a low number of highly purified CD34+ haploidentical cells: update of results

scientific article published on 01 April 2005

Umbilical Cord Blood Cytomegalovirus Serostatus Does Not Have an Impact on Outcomes of Umbilical Cord Blood Transplantation for Acute Leukemia

scientific article

Umbilical Cord Blood Natural Killer Cells, Their Characteristics, and Potential Clinical Applications.

scientific article published on 23 March 2017

Umbilical cord blood plasma contains soluble NKG2D ligands that mediate loss of natural killer cell function and cytotoxicity

scientific article

Unique Effects of Mycophenolate Mofetil on Cord Blood T Cells

scientific article published on 01 April 2014

Unrelated donor peripheral blood stem cell transplants incorporating pre-transplant in-vivo alemtuzumab are not associated with any increased risk of significant acute or chronic graft-versus-host disease.

scientific article published on 8 March 2011

Unrelated umbilical cord blood transplants in adults: Early recovery of neutrophils by supportive co-transplantation of a low number of highly purified peripheral blood CD34+ cells from an HLA-haploidentical donor.

scientific article published in June 2003

Uptake and use of recommendations for the diagnosis, severity scoring and management of chronic GVHD: an international survey of the EBMT-NCI Chronic GVHD Task Force.

scientific article published on 19 August 2013

Variations in practice in UK transplant centers: results of a related donor care survey

scientific article published on 05 September 2016

Vitamin D: is it important in haematopoietic stem cell transplantation? A review

scientific article published on 06 November 2018

[Treatment of umbilical cord blood units with interleukin-15 improves hematopoietic stem cell engraftment]

scientific article published on 17 June 2016

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