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List of works by Mark D Lessard

3-Dimensional histological reconstruction and imaging of the murine pancreas

scientific article

3D mapping of nanoscale crosslink heterogeneities in microgels

scientific article published on 05 September 2018

4Pi microscopy reveals an impaired three-dimensional mitochondrial network of pancreatic islet beta-cells, an experimental model of type-2 diabetes.

scientific article

A new approach for the study of the chemical composition of bordered pit membranes: 4Pi and confocal laser scanning microscopy.

scientific article

A novel physiological role for ARF1 in the formation of bidirectional tubules from the Golgi

scientific article published on 20 April 2017

Activation-induced cytidine deaminase-initiated off-target DNA breaks are detected and resolved during S phase.

scientific article

Attenuation of murine lysosomal storage disease by allogeneic neonatal bone marrow transplantation using costimulatory blockade and donor lymphocyte infusion without myeloablation

scientific article published on 17 February 2006

Centriolar association of ALMS1 and likely centrosomal functions of the ALMS motif-containing proteins C10orf90 and KIAA1731

scientific article

Distribution of mitochondrial DNA nucleoids inside the linear tubules vs. bulk parts of mitochondrial network as visualized by 4Pi microscopy.

scientific article published on 2 April 2015

Donor cell expansion is delayed following nonablative in utero transplantation to treat murine mucopolysaccharidosis type VII

scientific article published on 01 November 2003

Donor cell replacement in mice transplanted in utero is limited by immune-independent mechanisms

scientific article published on 01 September 2003

Early onset of lysosomal storage disease in a murine model of mucopolysaccharidosis type VII: undegraded substrate accumulates in many tissues in the fetus and very young MPS VII mouse

scientific article published on 01 July 2005

Hypoxic HepG2 cell adaptation decreases ATP synthase dimers and ATP production in inflated cristae by mitofilin down-regulation concomitant to MICOS clustering.

scientific article published on 17 February 2016

Implementation of a 4Pi-SMS super-resolution microscope

scientific article published on 16 December 2020

In utero fetal liver cell transplantation without toxic irradiation alleviates lysosomal storage in mice with mucopolysaccharidosis type VII

scientific article published on 01 September 2001

Mitochondrial oxidative phosphorylation and energetic status are reflected by morphology of mitochondrial network in INS-1E and HEP-G2 cells viewed by 4Pi microscopy.

scientific article

Nonablative neonatal marrow transplantation attenuates functional and physical defects of beta-glucuronidase deficiency.

scientific article published in March 2001

Successful allogeneic neonatal bone marrow transplantation devoid of myeloablation requires costimulatory blockade

scientific article published on 01 September 2003

The impact of entropy on the spatial organization of synaptonemal complexes within the cell nucleus

scientific article

Three-dimensional adaptive optical nanoscopy for thick specimen imaging at sub-50-nm resolution

scientific article published on 31 May 2021

Three-dimensional sub-100 nm resolution fluorescence microscopy of thick samples

scientific article

Transplanted ER-MP12hi20-58med/hi myeloid progenitors produce resident macrophages from marrow that are therapeutic for lysosomal storage disease

scientific article published on 01 January 2004

Ultra-High Resolution 3D Imaging of Whole Cells.

scientific article published on 06 July 2016

p63(+)Krt5(+) distal airway stem cells are essential for lung regeneration.

scientific article published on 12 November 2014