List of works by Clara V Alvarez

A GRFa2/Prop1/stem (GPS) cell niche in the pituitary

scientific article

Acipimox-mediated plasma free fatty acid depression per se stimulates growth hormone (GH) secretion in normal subjects and potentiates the response to other GH-releasing stimuli

scientific article published on 01 March 1996

Craniopharyngiomas express embryonic stem cell markers (SOX2, OCT4, KLF4, and SOX9) as pituitary stem cells but do not coexpress RET/GFRA3 receptors.

scientific article

Deletion of miRNA processing enzyme Dicer in POMC-expressing cells leads to pituitary dysfunction, neurodegeneration and development of obesity.

scientific article

Early evolutionary divergence between papillary and anaplastic thyroid cancers

scientific article published on 01 November 2019

Effect of neurotensin on growth hormone release in vivo

scientific article published on 01 January 1993

Energy balance regulation by thyroid hormones at central level

scientific article published on 23 May 2013

Expression of epithelial phenotype is enhanced by v-Ha-ras in rat endometrial cells immortalized by SV40 T antigen.

scientific article published on August 1993

Expression of exogenous proteins and short hairpin RNAs in human primary thyrocytes

scientific article published on 01 February 2010

Future perspectives in adult stem cell turnover: Implications for endocrine physiology and disease

scientific article published on 9 December 2016

GHRH proliferative action on somatotrophs is cell-type specific and dependent on Pit-1/GHF-1 expression.

scientific article

Ghrelin localization in the medulla of rat and human adrenal gland and in pheochromocytomas

scientific article published on 01 January 2008

Hypothalamic effects of thyroid hormones on metabolism.

scientific article published on 25 April 2014

Hypothalamic fatty acid metabolism mediates the orexigenic action of ghrelin.

scientific article published in May 2008

Identification of a paired box gene 8–peroxisome proliferator-activated receptor gamma (PAX8–PPARγ) rearrangement mosaicism in a patient with an autonomous functioning follicular thyroid carcinoma bearing an activating mutation in the TSH recept

article

Localization of growth hormone receptors in rat and human thyroid cells.

scientific article published on 9 October 2001

MKK6 controls T3-mediated browning of white adipose tissue

scientific article published on 11 October 2017

Mechanistic investigations into the encapsulation and release of small molecules and proteins from a supramolecular nucleoside gel in vitro and in vivo

scientific article published on 31 October 2019

Mitochondrial cristae-remodeling protein OPA1 in POMC neurons couples Ca<sup>2+</sup> homeostasis with adipose tissue lipolysis ⬇️

scientific article published on 02 August 2021

Pharmacological and Genetic Manipulation of p53 in Brown Fat at Adult But Not Embryonic Stages Regulates Thermogenesis and Body Weight in Male Mice

scientific article published on 16 May 2016

Physicochemical, pharmacokinetic and pharmacodynamic analyses of amphiphilic cyclodextrin-based nanoparticles designed to enhance intestinal delivery of insulin

scientific article published on 31 July 2018

Pituitary Cell Turnover: From Adult Stem Cell Recruitment through Differentiation to Death

scientific article

Plitidepsin has a cytostatic effect in human undifferentiated (anaplastic) thyroid carcinoma.

scientific article published on November 2005

Potent SHC tyrosine phosphorylation by epidermal growth factor at low receptor density or in the absence of receptor autophosphorylation sites

scientific journal article

Protamine nanocapsules as carriers for oral peptide delivery

scientific article published on 18 October 2018

Prothymosin alpha mRNA is expressed in competent and proliferating rat thyroid cells (FRTL-5) but is not sufficient to elicit cell progression through the cell cycle.

scientific article published on December 1993

Prothymosin alpha mRNA levels are invariant throughout the cell cycle ⬇️

scientific article published on April 25, 1992

Regulation of prothymosin alpha mRNA levels in rat pituitary tumor cells

scientific article published on 01 June 1993

Rewiring of the apoptotic TGF-β-SMAD/NFκB pathway through an oncogenic function of p27 in human papillary thyroid cancer.

scientific article published on 25 July 2016

Role of ghrelin in reproduction.

scientific article published on March 2007

Sequential Colocalization of ERa, PR, and AR Hormone Receptors Using Confocal Microscopy Enables New Insights into Normal Breast and Prostate Tissue and Cancers

scientific article published on 30 November 2020

Sirt1 inhibits the transcription factor CREB to regulate pituitary growth hormone synthesis

scientific journal article

Somatotropinomas, but not nonfunctioning pituitary adenomas, maintain a functional apoptotic RET/Pit1/ARF/p53 pathway that is blocked by excess GDNF.

scientific article published on 19 August 2014

Structural Requirements of the Epidermal Growth Factor Receptor for Tyrosine Phosphorylation of eps8 and eps15, Substrates Lacking Src SH2 Homology Domains ⬇️

scientific article published on July 7, 1995

TGF-beta-induced apoptosis in human thyrocytes is mediated by p27kip1 reduction and is overridden in neoplastic thyrocytes by NF-kappaB activation

scientific article published on 01 October 2003

TGF-beta1 actions on FRTL-5 cells provide a model for the physiological regulation of thyroid growth.

scientific article

Tackling Thyroid Cancer in Europe-The Challenges and Opportunities

scientific article published on 25 August 2022

The Molecular Registry of Pituitary Adenomas (REMAH): A bet of Spanish Endocrinology for the future of individualized medicine and translational research.

scientific article published on 15 April 2016

The dependence receptor Ret induces apoptosis in somatotrophs through a Pit-1/p53 pathway, preventing tumor growth.

scientific article published on 22 March 2007

The orexigenic effect of orexin-A revisited: dependence of an intact growth hormone axis.

scientific article published on 16 July 2013

The syndrome of central hypothyroidism and macroorchidism: IGSF1 controls TRHR and FSHB expression by differential modulation of pituitary TGFβ and Activin pathways.

scientific article published on 06 March 2017

Unmasking a new prognostic marker and therapeutic target from the GDNF-RET/PIT1/p14ARF/p53 pathway in acromegaly.

scientific article published on 8 April 2019

Why Should Growth Hormone (GH) Be Considered a Promising Therapeutic Agent for Arteriogenesis? Insights from the GHAS Trial

scientific article published on 27 March 2020

dsRNAi-mediated silencing of PIAS2beta specifically kills anaplastic carcinomas by mitotic catastrophe

scientific article published in 2024

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