List of works - Hendrik van Veen

A conserved mitochondrial ATP-binding cassette transporter exports glutathione polysulfide for cytosolic metal cofactor assembly

scientific article published on 8 July 2014

A critical role of a carboxylate in proton conduction by the ATP-binding cassette multidrug transporter LmrA.

scientific article published on 22 July 2005

A flexible cation binding site in the multidrug major facilitator superfamily transporter LmrP is associated with variable proton coupling

scientific article published on 14 May 2010

A functional steroid-binding element in an ATP-binding cassette multidrug transporter

scientific article

A high-throughput method for membrane protein solubility screening: the ultracentrifugation dispersity sedimentation assay

scientific article published on 13 June 2007

A multidrug ABC transporter with a taste for salt

scientific article published on 10 July 2009

A new dimer interface for an ABC transporter

scientific article published in September 2003

A new experimental approach to detect long-range conformational changes transmitted between the membrane and cytosolic domains of LmrA, a bacterial multidrug transporter

scientific article published in October 2002

ABC transporters and drug resistance in parasitic protozoa

scientific article

ABCG transporters: structure, substrate specificities and physiological roles : a brief overview.

scientific article published on December 2007

ATP-dependent substrate transport by the ABC transporter MsbA is proton-coupled

scientific article

Activation by gene amplification of pitB, encoding a third phosphate transporter of Escherichia coli K-12.

scientific article

An ABC transporter with a secondary-active multidrug translocator domain

scientific article published in December 2003

Antibiotic resistance: era of the multidrug pump.

scientific article

Arginine-482 is not essential for transport of antibiotics, primary bile acids and unconjugated sterols by the human breast cancer resistance protein (ABCG2).

scientific article published on January 2005

Assembly and operation of bacterial tripartite multidrug efflux pumps.

scientific article

Basic residues R260 and K357 affect the conformational dynamics of the major facilitator superfamily multidrug transporter LmrP

scientific article (publication date: 2012)

Caught in the act: ATP hydrolysis of an ABC-multidrug transporter followed by real-time magic angle spinning NMR.

scientific article published on 24 September 2008

Characterization of two phosphate transport systems in Acinetobacter johnsonii 210A.

scientific article

Cholate resistance in Lactococcus lactis is mediated by an ATP-dependent multispecific organic anion transporter.

scientific article

Cholic acid accumulation and its diminution by short-chain fatty acids in bifidobacteria

scientific article published in August 2003

Crystal structure of tripartite-type ABC transporter MacB from Acinetobacter baumannii

scientific article published on 6 November 2017

Dissection of the conformational cycle of the multidrug/lipidA ABC exporter MsbA.

scientific article published on November 2010

Drug efflux proteins in multidrug resistant bacteria.

scientific article published on August 1997

Drug-lipid A interactions on the Escherichia coli ABC transporter MsbA.

scientific article

Effects of nucleotide binding to LmrA: A combined MAS-NMR and solution NMR study.

scientific article published on 5 October 2015

Energetics of alanine, lysine, and proline transport in cytoplasmic membranes of the polyphosphate-accumulating Acinetobacter johnsonii strain 210A.

scientific article published on May 1994

Functional role of transmembrane helix 6 in drug binding and transport by the ABC transporter MsbA.

scientific article

Generation of a proton motive force by the excretion of metal-phosphate in the polyphosphate-accumulating Acinetobacter johnsonii strain 210A

scientific article published on 01 November 1994

Hoechst 33342 Is a Hidden "Janus" amongst Substrates for the Multidrug Efflux Pump LmrP

scientific article

Interaction of the breast cancer resistance protein with plant polyphenols

scientific article published on April 2004

MacB ABC transporter is a dimer whose ATPase activity and macrolide-binding capacity are regulated by the membrane fusion protein MacA.

scientific article published on 27 October 2008

MacB ABC transporter is a dimer whose ATPase activity and macrolide-binding capacity are regulated by the membrane fusion protein MacA. VOLUME 284 (2009) PAGES 1145-1154.

scientific article

Mass spectrometry of membrane transporters reveals subunit stoichiometry and interactions

scientific article

Mechanism and energetics of the secondary phosphate transport system of Acinetobacter johnsonii 210A

scientific article published on 01 September 1993

Membrane-bound ATPase contributes to hop resistance of Lactobacillus brevis.

scientific article

Metabolites of ginsenosides as novel BCRP inhibitors

scientific article published on 4 May 2006

Modulation of p-glycoprotein and breast cancer resistance protein by some prescribed corticosteroids

scientific article published on 25 January 2006

Molecular basis of multidrug transport by ABC transporters

scientific article published on 24 December 2008

Molecular basis of multidrug transport by ATP-binding cassette transporters: a proposed two-cylinder engine model.

scientific article

Molecular disruption of the power stroke in the ATP-binding cassette transport protein MsbA.

scientific article published on 10 January 2013

Molecular pharmacological characterization of two multidrug transporters in Lactococcus lactis.

scientific article

Molecular properties of bacterial multidrug transporters

scientific article (publication date: December 2000)

Multidrug efflux pumps: structure, function and regulation

scientific article published on 01 September 2018

Multidrug resistance in Lactococcus lactis: evidence for ATP-dependent drug extrusion from the inner leaflet of the cytoplasmic membrane.

scientific article

Multidrug resistance in lactic acid bacteria: molecular mechanisms and clinical relevance.

scientific article

Multidrug transport by the ABC transporter Sav1866 from Staphylococcus aureus

scientific article

Multidrug transport protein norM from vibrio cholerae simultaneously couples to sodium- and proton-motive force

scientific article

New light on multidrug binding by an ATP-binding-cassette transporter

scientific article

New structure model for the ATP-binding cassette multidrug transporter LmrA

scientific article published on 24 May 2007

On the energy-dependence of Hoechst 33342 transport by the ABC transporter LmrA.

scientific article published on 26 October 2007

Plasmodium falciparum expresses a multidrug resistance-associated protein

scientific article (publication date: 13 August 2004)

Powering the ABC multidrug exporter LmrA: How nucleotides embrace the ion-motive force

scientific article published on 19 September 2018

Probing the ATP hydrolysis cycle of the ABC multidrug transporter LmrA by pulsed EPR spectroscopy.

scientific article published on 21 March 2012

Probing the Molecular Dynamics of the ABC Multidrug Transporter LmrA by Deuterium Solid-State Nuclear Magnetic Resonance†

article

Promiscuous partnering and independent activity of MexB, the multidrug transporter protein from Pseudomonas aeruginosa

scientific article published in September 2010

Proton motive force-driven and ATP-dependent drug extrusion systems in multidrug-resistant Lactococcus lactis.

scientific article

Recent developments in the biochemistry and ecology of enhanced biological phosphorus removal.

scientific article published in March 2000

Relocation of active site carboxylates in major facilitator superfamily multidrug transporter LmrP reveals plasticity in proton interactions

scientific article (publication date: 5 December 2016)

Restrictive use of detergents in the functional reconstitution of the secondary multidrug transporter LmrP.

scientific article

Reversible transport by the ATP-binding cassette multidrug export pump LmrA: ATP synthesis at the expense of downhill ethidium uptake

scientific article published on 05 December 2003

S-decyl-glutathione nonspecifically stimulates the ATPase activity of the nucleotide-binding domains of the human multidrug resistance-associated protein, MRP1 (ABCC1).

scientific article

SUBSTRATE-BINDING SITES IN ABC TRANSPORTERS

Secondary and tertiary structure changes of reconstituted LmrA induced by nucleotide binding or hydrolysis. A fourier transform attenuated total reflection infrared spectroscopy and tryptophan fluorescence quenching analysis.

scientific article

Similarities between ATP-dependent and ion-coupled multidrug transporters.

scientific article

Sterol transport by the human breast cancer resistance protein (ABCG2) expressed in Lactococcus lactis

scientific article published on 28 March 2003

Structural biology: Last of the multidrug transporters.

scientific article

Structure and Dynamics of the Membrane-Embedded Domain of LmrA Investigated by Coupling Polarized ATR-FTIR Spectroscopy and1H/2H Exchange†

scientific article published on 01 October 2001

Structure and function of multidrug transporters.

scientific article

Structure of an antibacterial peptide ATP-binding cassette transporter in a novel outward occluded state

scientific article

Structure of the MacAB-TolC ABC-type tripartite multidrug efflux pump.

scientific article published on 15 May 2017

Structure, mechanism and cooperation of bacterial multidrug transporters

scientific article

Structure-function analysis of multidrug transporters in Lactococcus lactis.

scientific article

Structures and functions of mitochondrial ABC transporters.

scientific article

Substrate binding stabilizes a pre-translocation intermediate in the ATP-binding cassette transport protein MsbA

scientific article published on 13 June 2013

Substrate specificity of the two phosphate transport systems of Acinetobacter johnsonii 210A in relation to phosphate speciation in its aquatic environment

scientific article published on 01 June 1994

The ATP binding cassette multidrug transporter LmrA and lipid transporter MsbA have overlapping substrate specificities

scientific article

The Lactococcal lmrP Gene Encodes a Proton Motive Force- dependent Drug Transporter ⬇️

scientific article published on November 3, 1995

The choreography of multidrug export

scientific article published on June 2011

The homodimeric ATP-binding cassette transporter LmrA mediates multidrug transport by an alternating two-site (two-cylinder engine) mechanism

scientific article (publication date: June 2000)

The lactococcal secondary multidrug transporter LmrP confers resistance to lincosamides, macrolides, streptogramins and tetracyclines.

scientific article

The multidrug transporter LmrP protein mediates selective calcium efflux

scientific article

The purified and functionally reconstituted multidrug transporter LmrA of Lactococcus lactis mediates the transbilayer movement of specific fluorescent phospholipids.

scientific article published in December 1999

The secondary multidrug transporter LmrP contains multiple drug interaction sites.

scientific article published in October 1999

Towards the molecular mechanism of prokaryotic and eukaryotic multidrug transporters.

scientific article

Translocation of metal phosphate via the phosphate inorganic transport system of Escherichia coli.

scientific article

Tripartite transporters as mechano-transmitters in periplasmic alternating-access mechanisms

scientific article published on 16 September 2020

Tuning the drug efflux activity of an ABC transporter in vivo by in vitro selected DARPin binders

scientific article

Two Proton Translocation Pathways in a Secondary Active Multidrug Transporter

scientific article published on 01 January 2007

Understanding polyspecificity of multidrug ABC transporters: closing in on the gaps in ABCB1

scientific article

cGMP and glutathione-conjugate transport in human erythrocytes

scientific article published on September 2003

β-Lactam selectivity of multidrug transporters AcrB and AcrD resides in the proximal binding pocket

scientific article

List of works by Hendrik van Veen

A conserved mitochondrial ATP-binding cassette transporter exports glutathione polysulfide for cytosolic metal cofactor assembly

A critical role of a carboxylate in proton conduction by the ATP-binding cassette multidrug transporter LmrA.

A flexible cation binding site in the multidrug major facilitator superfamily transporter LmrP is associated with variable proton coupling

A functional steroid-binding element in an ATP-binding cassette multidrug transporter

A high-throughput method for membrane protein solubility screening: the ultracentrifugation dispersity sedimentation assay

A multidrug ABC transporter with a taste for salt

A new dimer interface for an ABC transporter

A new experimental approach to detect long-range conformational changes transmitted between the membrane and cytosolic domains of LmrA, a bacterial multidrug transporter

ABC transporters and drug resistance in parasitic protozoa

ABCG transporters: structure, substrate specificities and physiological roles : a brief overview.

ATP-dependent substrate transport by the ABC transporter MsbA is proton-coupled

Activation by gene amplification of pitB, encoding a third phosphate transporter of Escherichia coli K-12.

An ABC transporter with a secondary-active multidrug translocator domain

Antibiotic resistance: era of the multidrug pump.

Arginine-482 is not essential for transport of antibiotics, primary bile acids and unconjugated sterols by the human breast cancer resistance protein (ABCG2).

Assembly and operation of bacterial tripartite multidrug efflux pumps.

Basic residues R260 and K357 affect the conformational dynamics of the major facilitator superfamily multidrug transporter LmrP

Caught in the act: ATP hydrolysis of an ABC-multidrug transporter followed by real-time magic angle spinning NMR.

Characterization of two phosphate transport systems in Acinetobacter johnsonii 210A.

Cholate resistance in Lactococcus lactis is mediated by an ATP-dependent multispecific organic anion transporter.

Cholic acid accumulation and its diminution by short-chain fatty acids in bifidobacteria

Crystal structure of tripartite-type ABC transporter MacB from Acinetobacter baumannii

Dissection of the conformational cycle of the multidrug/lipidA ABC exporter MsbA.

Drug efflux proteins in multidrug resistant bacteria.

Drug-lipid A interactions on the Escherichia coli ABC transporter MsbA.

Effects of nucleotide binding to LmrA: A combined MAS-NMR and solution NMR study.

Energetics of alanine, lysine, and proline transport in cytoplasmic membranes of the polyphosphate-accumulating Acinetobacter johnsonii strain 210A.

Functional role of transmembrane helix 6 in drug binding and transport by the ABC transporter MsbA.

Generation of a proton motive force by the excretion of metal-phosphate in the polyphosphate-accumulating Acinetobacter johnsonii strain 210A

Hoechst 33342 Is a Hidden "Janus" amongst Substrates for the Multidrug Efflux Pump LmrP

Interaction of the breast cancer resistance protein with plant polyphenols

MacB ABC transporter is a dimer whose ATPase activity and macrolide-binding capacity are regulated by the membrane fusion protein MacA.

MacB ABC transporter is a dimer whose ATPase activity and macrolide-binding capacity are regulated by the membrane fusion protein MacA. VOLUME 284 (2009) PAGES 1145-1154.

Mass spectrometry of membrane transporters reveals subunit stoichiometry and interactions

Mechanism and energetics of the secondary phosphate transport system of Acinetobacter johnsonii 210A

Membrane-bound ATPase contributes to hop resistance of Lactobacillus brevis.

Metabolites of ginsenosides as novel BCRP inhibitors

Modulation of p-glycoprotein and breast cancer resistance protein by some prescribed corticosteroids

Molecular basis of multidrug transport by ABC transporters

Molecular basis of multidrug transport by ATP-binding cassette transporters: a proposed two-cylinder engine model.

Molecular disruption of the power stroke in the ATP-binding cassette transport protein MsbA.

Molecular pharmacological characterization of two multidrug transporters in Lactococcus lactis.

Molecular properties of bacterial multidrug transporters

Multidrug efflux pumps: structure, function and regulation

Multidrug resistance in Lactococcus lactis: evidence for ATP-dependent drug extrusion from the inner leaflet of the cytoplasmic membrane.

Multidrug resistance in lactic acid bacteria: molecular mechanisms and clinical relevance.

Multidrug transport by the ABC transporter Sav1866 from Staphylococcus aureus

Multidrug transport protein norM from vibrio cholerae simultaneously couples to sodium- and proton-motive force

New light on multidrug binding by an ATP-binding-cassette transporter

New structure model for the ATP-binding cassette multidrug transporter LmrA

On the energy-dependence of Hoechst 33342 transport by the ABC transporter LmrA.

Plasmodium falciparum expresses a multidrug resistance-associated protein

Powering the ABC multidrug exporter LmrA: How nucleotides embrace the ion-motive force

Probing the ATP hydrolysis cycle of the ABC multidrug transporter LmrA by pulsed EPR spectroscopy.

Probing the Molecular Dynamics of the ABC Multidrug Transporter LmrA by Deuterium Solid-State Nuclear Magnetic Resonance†

Promiscuous partnering and independent activity of MexB, the multidrug transporter protein from Pseudomonas aeruginosa

Proton motive force-driven and ATP-dependent drug extrusion systems in multidrug-resistant Lactococcus lactis.

Recent developments in the biochemistry and ecology of enhanced biological phosphorus removal.

Relocation of active site carboxylates in major facilitator superfamily multidrug transporter LmrP reveals plasticity in proton interactions

Restrictive use of detergents in the functional reconstitution of the secondary multidrug transporter LmrP.

Reversible transport by the ATP-binding cassette multidrug export pump LmrA: ATP synthesis at the expense of downhill ethidium uptake

S-decyl-glutathione nonspecifically stimulates the ATPase activity of the nucleotide-binding domains of the human multidrug resistance-associated protein, MRP1 (ABCC1).

SUBSTRATE-BINDING SITES IN ABC TRANSPORTERS

Secondary and tertiary structure changes of reconstituted LmrA induced by nucleotide binding or hydrolysis. A fourier transform attenuated total reflection infrared spectroscopy and tryptophan fluorescence quenching analysis.

Similarities between ATP-dependent and ion-coupled multidrug transporters.

Sterol transport by the human breast cancer resistance protein (ABCG2) expressed in Lactococcus lactis

Structural biology: Last of the multidrug transporters.

Structure and Dynamics of the Membrane-Embedded Domain of LmrA Investigated by Coupling Polarized ATR-FTIR Spectroscopy and1H/2H Exchange†

Structure and function of multidrug transporters.

Structure of an antibacterial peptide ATP-binding cassette transporter in a novel outward occluded state

Structure of the MacAB-TolC ABC-type tripartite multidrug efflux pump.

Structure, mechanism and cooperation of bacterial multidrug transporters

Structure-function analysis of multidrug transporters in Lactococcus lactis.

Structures and functions of mitochondrial ABC transporters.

Substrate binding stabilizes a pre-translocation intermediate in the ATP-binding cassette transport protein MsbA

Substrate specificity of the two phosphate transport systems of Acinetobacter johnsonii 210A in relation to phosphate speciation in its aquatic environment

The ATP binding cassette multidrug transporter LmrA and lipid transporter MsbA have overlapping substrate specificities

The Lactococcal lmrP Gene Encodes a Proton Motive Force- dependent Drug Transporter ⬇️

The choreography of multidrug export