List of works - Graham Anderson

A distinct subset of podoplanin (gp38) expressing F4/80+ macrophages mediate phagocytosis and are induced following zymosan peritonitis

scientific article published on 2 August 2010

A novel method of cell separation based on dual parameter immunomagnetic cell selection

scientific article published on 01 March 1999

A novel method to allow noninvasive, longitudinal imaging of the murine immune system in vivo

scientific article

A novel method to identify Post-Aire stages of medullary thymic epithelial cell differentiation

scientific article published on 26 August 2020

A roadmap for thymic epithelial cell development.

scientific article published on July 2009

A type 2 cytokine axis for thymus emigration.

scientific article published on 10 July 2017

AIRE's CARD revealed, a new structure for central tolerance provokes transcriptional plasticity

scientific article

Abrogation of CD30 and OX40 signals prevents autoimmune disease in FoxP3-deficient mice.

scientific article

Absence of thymus crosstalk in the fetus does not preclude hematopoietic induction of a functional thymus in the adult

scientific article published in September 2009

Affinity for self antigen selects Treg cells with distinct functional properties

scientific article published on August 2016

Aire controls the recirculation of murine Foxp3+ regulatory T-cells back to the thymus.

scientific article published on 29 December 2017

An epithelial progenitor pool regulates thymus growth

scientific article published on 01 November 2008

An essential role for medullary thymic epithelial cells during the intrathymic development of invariant NKT cells

scientific article published on 07 February 2014

An essential role for the IL-7 receptor during intrathymic expansion of the positively selected neonatal T cell repertoire

scientific article published on 01 September 2000

Analysis of cytokine gene expression in subpopulations of freshly isolated thymocytes and thymic stromal cells using semiquantitative polymerase chain reaction

scientific article published on 01 April 1993

Border control: Anatomical origins of the thymus medulla

scientific article published on 24 June 2015

CCR7 Controls Thymus Recirculation, but Not Production and Emigration, of Foxp3(+) T Cells

scientific article published on 27 January 2016

CCRL1/ACKR4 is expressed in key thymic microenvironments but is dispensable for T lymphopoiesis at steady state in adult mice

scientific article published on 16 January 2015

CD117⁺ CD3⁻ CD56⁻ OX40Lhigh cells express IL-22 and display an LTi phenotype in human secondary lymphoid tissues.

scientific article published on 25 May 2011

CD248/Endosialin is dynamically expressed on a subset of stromal cells during lymphoid tissue development, splenic remodeling and repair.

scientific article published on 3 July 2007

CXCR4, but not CXCR3, drives CD8 + T‐cell entry into and migration through the murine bone marrow

scientific article published on 15 February 2019

Cellular interactions in thymocyte development.

scientific article published on January 1996

Chemokine receptor expression defines heterogeneity in the earliest thymic migrants

article

Clonal Analysis Reveals Uniformity in the Molecular Profile and Lineage Potential of CCR9+ and CCR9− Thymus-Settling Progenitors ⬇️

scientific article published on March 18, 2011

Co-ordination of intrathymic self-representation

scientific article published on 01 September 2015

Con A activates an Akt/PKB dependent survival mechanism to modulate TCR induced cell death in double positive thymocytes.

scientific article published in June 2003

Context-Dependent Development of Lymphoid Stroma from Adult CD34(+) Adventitial Progenitors

scientific article

Control of the thymic medulla and its influence on αβT-cell development

scientific article

Critical synergy of CD30 and OX40 signals in CD4 T cell homeostasis and Th1 immunity to Salmonella.

scientific article published in March 2008

Cutting edge: lymphoid tissue inducer cells maintain memory CD4 T cells within secondary lymphoid tissue

scientific article published on August 2012

Development of functional thymic epithelial cells occurs independently of lymphostromal interactions.

scientific article published on 29 August 2005

Developmentally regulated availability of RANKL and CD40 ligand reveals distinct mechanisms of fetal and adult cross-talk in the thymus medulla

scientific article published on 14 November 2012

Differential requirement for CCR4 and CCR7 during the development of innate and adaptive αβT cells in the adult thymus.

scientific article

Differential requirement for CCR4 in the maintenance but not establishment of the invariant Vγ5(+) dendritic epidermal T-cell pool

scientific journal article

Differential requirement for mesenchyme in the proliferation and maturation of thymic epithelial progenitors.

scientific article published on 14 July 2003

Discrimination between maintenance- and differentiation-inducing signals during initial and intermediate stages of positive selection

scientific article published on 01 August 1997

Diversity in medullary thymic epithelial cells controls the activity and availability of iNKT cells

scientific article published on 04 May 2020

Dynamic changes in intrathymic ILC populations during murine neonatal development

article

Endothelial cells act as gatekeepers for LTβR-dependent thymocyte emigration

scientific article published on 13 November 2018

Enhanced selection of FoxP3+ T-regulatory cells protects CTLA-4-deficient mice from CNS autoimmune disease.

scholarly article

EphrinB1-EphB signaling regulates thymocyte-epithelium interactions involved in functional T cell development.

scientific article published in September 2007

Establishment and functioning of intrathymic microenvironments.

scientific article

Evolving strategies for cancer and autoimmunity: back to the future

scientific article (publication date: 2014)

Expression of the Ian family of putative GTPases during T cell development and description of an Ian with three sets of GTP/GDP-binding motifs

scientific journal article

Formation of the Intrathymic Dendritic Cell Pool Requires CCL21-Mediated Recruitment of CCR7+ Progenitors to the Thymus.

scientific article published on 21 May 2018

Function of CD4+CD3- cells in relation to B- and T-zone stroma in spleen

scientific article published on 03 October 2006

Generating intrathymic microenvironments to establish T-cell tolerance.

scientific article published on December 2007

Generation of both cortical and Aire(+) medullary thymic epithelial compartments from CD205(+) progenitors

scientific article published on 11 February 2013

Generation of diversity in thymic epithelial cells.

scientific article published on 20 March 2017

Hepatocyte Growth Factor Receptor c-Met Instructs T Cell Cardiotropism and Promotes T Cell Migration to the Heart via Autocrine Chemokine Release

scientific article

Heterogeneity of lymphoid tissue inducer cell populations present in embryonic and adult mouse lymphoid tissues.

scientific article

IgG Responses to Porins and Lipopolysaccharide within an Outer Membrane-Based Vaccine against Nontyphoidal Salmonella Develop at Discordant Rates

scientific article published on 6 March 2018

In vitro models of T cell development

scientific article published on 01 February 1999

Increased Production of IL-17A-Producing γδ T Cells in the Thymus of Filaggrin-Deficient Mice.

scientific article

Induction of thymocyte positive selection does not convey immediate resistance to negative selection.

scientific article published in February 2002

Invariant NKT Cells and Control of the Thymus Medulla

scientific article published on 01 May 2018

Involvement of CCR9 at multiple stages of adult T lymphopoiesis

article

Laying bare the nude mouse gene

scientific article published on 01 February 2015

Ly49H+ NK cells migrate to and protect splenic white pulp stroma from murine cytomegalovirus infection.

scientific article

Lymphoid tissue inducer cells and the evolution of CD4 dependent high-affinity antibody responses.

scientific article published on January 2010

Lymphoid tissue inducer cells in adaptive CD4 T cell dependent responses.

scientific article published on 14 April 2008

Lymphoid tissue inducer cells: innate cells critical for CD4+ T cell memory responses? ⬇️

scientific article published on January 19, 2012

Lymphoid tissue inducer cells: pivotal cells in the evolution of CD4 immunity and tolerance?

scientific article published on 29 February 2012

Lymphotoxin a-dependent and -independent signals regulate stromal organizer cell homeostasis during lymph node organogenesis.

scientific article published on 25 May 2007

Lymphotoxin signals from positively selected thymocytes regulate the terminal differentiation of medullary thymic epithelial cells

scientific article published on 22 September 2010

Lymphotoxin β Receptor Controls T Cell Progenitor Entry to the Thymus.

scientific article published on 22 August 2016

Lymphotoxin-β receptor signaling through NF-κB2-RelB pathway reprograms adipocyte precursors as lymph node stromal cells

scientific article published on 30 August 2012

Medullary Thymic epithelial cell progenitors: hidden in plain sight.

scientific article published on 8 May 2017

Mesenchymal cells regulate retinoic acid receptor-dependent cortical thymic epithelial cell homeostasis.

scientific article published on 13 April 2012

Microenvironmental regulation of Notch signalling in T cell development.

scientific article

Microenvironmental regulation of T cell development in the thymus.

scientific article

Modeling TCR signaling complex formation in positive selection.

scientific article published in September 2003

Mutation in the TCRα subunit constant gene (TRAC) leads to a human immunodeficiency disorder characterized by a lack of TCRαβ+ T cells

scientific article

NK cells protect secondary lymphoid tissue from cytomegalovirus via a CD30-dependent mechanism

scientific article published on 01 October 2009

Natural Th17 cells are critically regulated by functional medullary thymic microenvironments.

scientific article

Neonatal and adult CD4+ CD3- cells share similar gene expression profile, and neonatal cells up-regulate OX40 ligand in response to TL1A (TNFSF15).

scientific article published in September 2006

Normal T cell selection occurs in CD205-deficient thymic microenvironments

scientific article

OX40 and CD30 signals in CD4+ T‐cell effector and memory function: a distinct role for lymphoid tissue inducer cells in maintaining CD4+ T‐cell memory but not effector function ⬇️

scientific article published on November 1, 2011

OX40 ligand and CD30 ligand are expressed on adult but not neonatal CD4+CD3- inducer cells: evidence that IL-7 signals regulate CD30 ligand but not OX40 ligand expression

scientific article published on 01 June 2005

One for all and all for one: thymic epithelial stem cells and regeneration

scientific article

Ontogeny of stromal organizer cells during lymph node development.

scientific article

Osteoprotegerin-Mediated Homeostasis of Rank+ Thymic Epithelial Cells Does Not Limit Foxp3+ Regulatory T Cell Development.

scientific article published on 7 August 2015

PDGFRalpha-expressing mesenchyme regulates thymus growth and the availability of intrathymic niches

scientific article published on 28 September 2006

Piecing together the thymic puzzle.

scientific article

Positive selection by purified MHC class II+ thymic epithelial cells in vitro: costimulatory signals mediated by B7 are not involved.

scientific article published on January 1994

Positive selection of thymocytes: the long and winding road.

scientific article

Prdm1 Regulates Thymic Epithelial Function To Prevent Autoimmunity

scientific article published on 12 July 2017

Preparation of 2-dGuo-treated thymus organ cultures.

scientific article published on 28 August 2008

Progression through key stages of haemopoiesis is dependent on distinct threshold levels of c-Myb.

scientific article

Progressive Changes in CXCR4 Expression That Define Thymocyte Positive Selection Are Dispensable For Both Innate and Conventional αβT-cell Development

scientific article

RANK links thymic regulatory T cells to fetal loss and gestational diabetes in pregnancy

scientific article published on 23 December 2020

RANK signals from CD4(+)3(-) inducer cells regulate development of Aire-expressing epithelial cells in the thymic medulla

scientific article published on 14 May 2007

Rank signaling links the development of invariant γδ T cell progenitors and Aire(+) medullary epithelium

scientific article

Reaggregate thymus cultures.

scientific article published on 28 August 2008

Redefining epithelial progenitor potential in the developing thymus

scientific article published in September 2007

Redefining thymus medulla specialization for central tolerance

scientific article published on 22 August 2017

Relb acts downstream of medullary thymic epithelial stem cells and is essential for the emergence of RANK(+) medullary epithelial progenitors.

scientific article published on 25 January 2016

Resolving Salmonella infection reveals dynamic and persisting changes in murine bone marrow progenitor cell phenotype and function

scientific article published on 11 June 2014

Retinoic Acid Signaling in Thymic Epithelial Cells Regulates Thymopoiesis

scientific article published on 30 May 2018

Sequential phases in the development of Aire-expressing medullary thymic epithelial cells involve distinct cellular input

scientific article published in April 2008

Serial progression of cortical and medullary thymic epithelial microenvironments

scientific article

Splenic stromal cells mediate IL-7 independent adult lymphoid tissue inducer cell survival.

scientific article published in February 2010

Studies on T cell maturation on defined thymic stromal cell populations in vitro

scientific article published on September 1992

Synergistic OX40 and CD30 signals sustain CD8+ T cells during antigenic challenge.

scientific article published in August 2009

TSCOT+ thymic epithelial cell-mediated sensitive CD4 tolerance by direct presentation

scientific journal article

The Global Thymus Network: past, present and future

scientific article published on 08 April 2009

The primordial thymus: everything you need under one roof

scientific article published on 01 August 2014

The role of lymphoid tissue inducer cells in splenic white pulp development

scientific article published on 01 November 2007

The role of the thymus during T-lymphocyte development in vitro.

scientific article

The survival of memory CD4+ T cells within the gut lamina propria requires OX40 and CD30 signals

scientific article published on 28 September 2009

The thymic medulla is required for Foxp3+ regulatory but not conventional CD4+ thymocyte development

scientific article published on 25 March 2013

The thymus and T-cell commitment: the right niche for Notch?

scientific article published on July 2006

The thymus and rheumatology: should we care?

scientific article

Thymic Epithelial Cells.

scientific article published on 10 February 2017

Thymic function is maintained during Salmonella-induced atrophy and recovery

scientific article published on 19 September 2012

Thymus medulla fosters generation of natural Treg cells, invariant γδ T cells, and invariant NKT cells: what we learn from intrathymic migration

scientific article

Trans-endocytosis of CD80 and CD86: a molecular basis for the cell-extrinsic function of CTLA-4

scientific article

Transplantation of embryonic spleen tissue reveals a role for adult non-lymphoid cells in initiating lymphoid tissue organization.

scientific article published on January 2009

Use of explant technology in the study of in vitro immune responses

scientific article published on 01 July 1998

Wnt-4 protects thymic epithelial cells against dexamethasone-induced senescence.

scientific article

Wnt4 and LAP2alpha as pacemakers of thymic epithelial senescence

scientific article

List of works by Graham Anderson

A distinct subset of podoplanin (gp38) expressing F4/80+ macrophages mediate phagocytosis and are induced following zymosan peritonitis

A novel method of cell separation based on dual parameter immunomagnetic cell selection

A novel method to allow noninvasive, longitudinal imaging of the murine immune system in vivo

A novel method to identify Post-Aire stages of medullary thymic epithelial cell differentiation

A roadmap for thymic epithelial cell development.

A type 2 cytokine axis for thymus emigration.

AIRE's CARD revealed, a new structure for central tolerance provokes transcriptional plasticity

Abrogation of CD30 and OX40 signals prevents autoimmune disease in FoxP3-deficient mice.

Absence of thymus crosstalk in the fetus does not preclude hematopoietic induction of a functional thymus in the adult

Affinity for self antigen selects Treg cells with distinct functional properties

Aire controls the recirculation of murine Foxp3+ regulatory T-cells back to the thymus.

An epithelial progenitor pool regulates thymus growth

An essential role for medullary thymic epithelial cells during the intrathymic development of invariant NKT cells

An essential role for the IL-7 receptor during intrathymic expansion of the positively selected neonatal T cell repertoire

Analysis of cytokine gene expression in subpopulations of freshly isolated thymocytes and thymic stromal cells using semiquantitative polymerase chain reaction

Border control: Anatomical origins of the thymus medulla

CCR7 Controls Thymus Recirculation, but Not Production and Emigration, of Foxp3(+) T Cells

CCRL1/ACKR4 is expressed in key thymic microenvironments but is dispensable for T lymphopoiesis at steady state in adult mice

CD117⁺ CD3⁻ CD56⁻ OX40Lhigh cells express IL-22 and display an LTi phenotype in human secondary lymphoid tissues.

CD248/Endosialin is dynamically expressed on a subset of stromal cells during lymphoid tissue development, splenic remodeling and repair.

CXCR4, but not CXCR3, drives CD8 + T‐cell entry into and migration through the murine bone marrow

Cellular interactions in thymocyte development.

Chemokine receptor expression defines heterogeneity in the earliest thymic migrants

Clonal Analysis Reveals Uniformity in the Molecular Profile and Lineage Potential of CCR9+ and CCR9− Thymus-Settling Progenitors ⬇️

Co-ordination of intrathymic self-representation

Con A activates an Akt/PKB dependent survival mechanism to modulate TCR induced cell death in double positive thymocytes.

Context-Dependent Development of Lymphoid Stroma from Adult CD34(+) Adventitial Progenitors

Control of the thymic medulla and its influence on αβT-cell development

Critical synergy of CD30 and OX40 signals in CD4 T cell homeostasis and Th1 immunity to Salmonella.

Cutting edge: lymphoid tissue inducer cells maintain memory CD4 T cells within secondary lymphoid tissue

Development of functional thymic epithelial cells occurs independently of lymphostromal interactions.

Developmentally regulated availability of RANKL and CD40 ligand reveals distinct mechanisms of fetal and adult cross-talk in the thymus medulla

Differential requirement for CCR4 and CCR7 during the development of innate and adaptive αβT cells in the adult thymus.

Differential requirement for CCR4 in the maintenance but not establishment of the invariant Vγ5(+) dendritic epidermal T-cell pool

Differential requirement for mesenchyme in the proliferation and maturation of thymic epithelial progenitors.

Discrimination between maintenance- and differentiation-inducing signals during initial and intermediate stages of positive selection

Diversity in medullary thymic epithelial cells controls the activity and availability of iNKT cells

Dynamic changes in intrathymic ILC populations during murine neonatal development

Endothelial cells act as gatekeepers for LTβR-dependent thymocyte emigration

Enhanced selection of FoxP3+ T-regulatory cells protects CTLA-4-deficient mice from CNS autoimmune disease.

EphrinB1-EphB signaling regulates thymocyte-epithelium interactions involved in functional T cell development.

Establishment and functioning of intrathymic microenvironments.

Evolving strategies for cancer and autoimmunity: back to the future

Expression of the Ian family of putative GTPases during T cell development and description of an Ian with three sets of GTP/GDP-binding motifs

Formation of the Intrathymic Dendritic Cell Pool Requires CCL21-Mediated Recruitment of CCR7+ Progenitors to the Thymus.

Function of CD4+CD3- cells in relation to B- and T-zone stroma in spleen

Generating intrathymic microenvironments to establish T-cell tolerance.

Generation of both cortical and Aire(+) medullary thymic epithelial compartments from CD205(+) progenitors

Generation of diversity in thymic epithelial cells.

Hepatocyte Growth Factor Receptor c-Met Instructs T Cell Cardiotropism and Promotes T Cell Migration to the Heart via Autocrine Chemokine Release

Heterogeneity of lymphoid tissue inducer cell populations present in embryonic and adult mouse lymphoid tissues.

IgG Responses to Porins and Lipopolysaccharide within an Outer Membrane-Based Vaccine against Nontyphoidal Salmonella Develop at Discordant Rates

In vitro models of T cell development

Increased Production of IL-17A-Producing γδ T Cells in the Thymus of Filaggrin-Deficient Mice.

Induction of thymocyte positive selection does not convey immediate resistance to negative selection.

Invariant NKT Cells and Control of the Thymus Medulla

Involvement of CCR9 at multiple stages of adult T lymphopoiesis

Laying bare the nude mouse gene

Ly49H+ NK cells migrate to and protect splenic white pulp stroma from murine cytomegalovirus infection.

Lymphoid tissue inducer cells and the evolution of CD4 dependent high-affinity antibody responses.

Lymphoid tissue inducer cells in adaptive CD4 T cell dependent responses.

Lymphoid tissue inducer cells: innate cells critical for CD4+ T cell memory responses? ⬇️

Lymphoid tissue inducer cells: pivotal cells in the evolution of CD4 immunity and tolerance?

Lymphotoxin a-dependent and -independent signals regulate stromal organizer cell homeostasis during lymph node organogenesis.

Lymphotoxin signals from positively selected thymocytes regulate the terminal differentiation of medullary thymic epithelial cells

Lymphotoxin β Receptor Controls T Cell Progenitor Entry to the Thymus.

Lymphotoxin-β receptor signaling through NF-κB2-RelB pathway reprograms adipocyte precursors as lymph node stromal cells

Medullary Thymic epithelial cell progenitors: hidden in plain sight.

Mesenchymal cells regulate retinoic acid receptor-dependent cortical thymic epithelial cell homeostasis.

Microenvironmental regulation of Notch signalling in T cell development.

Microenvironmental regulation of T cell development in the thymus.

Modeling TCR signaling complex formation in positive selection.

Mutation in the TCRα subunit constant gene (TRAC) leads to a human immunodeficiency disorder characterized by a lack of TCRαβ+ T cells

NK cells protect secondary lymphoid tissue from cytomegalovirus via a CD30-dependent mechanism

Natural Th17 cells are critically regulated by functional medullary thymic microenvironments.

Neonatal and adult CD4+ CD3- cells share similar gene expression profile, and neonatal cells up-regulate OX40 ligand in response to TL1A (TNFSF15).

Normal T cell selection occurs in CD205-deficient thymic microenvironments

OX40 and CD30 signals in CD4+ T‐cell effector and memory function: a distinct role for lymphoid tissue inducer cells in maintaining CD4+ T‐cell memory but not effector function ⬇️

OX40 ligand and CD30 ligand are expressed on adult but not neonatal CD4+CD3- inducer cells: evidence that IL-7 signals regulate CD30 ligand but not OX40 ligand expression