List of works - Filipa Mendes

99mTc(I)/Re(I) tricarbonyl complexes for in vivo targeting of melanotic melanoma: Synthesis and biological evaluation

scientific article

A Multifunctional Radiotheranostic Agent for Dual Targeting of Breast Cancer Cells

scientific article

A comparison of 14 antibodies for the biochemical detection of the cystic fibrosis transmembrane conductance regulator protein.

scientific article

Anthracene-terpyridine metal complexes as new G-quadruplex DNA binders.

scientific article

Antibodies for CFTR studies.

scientific article published in August 2004

Anticancer activity of structurally related ruthenium(II) cyclopentadienyl complexes

scientific article published on 23 February 2014

Application of microwave-assisted heating to the synthesis of Pt(II) complexes

article published in 2015

Assessment of CFTR localisation in native airway epithelial cells obtained by nasal brushing.

scientific article published in August 2004

BAG-1 stabilizes mutant F508del-CFTR in a ubiquitin-like-domain-dependent manner

scientific article published on 5 October 2012

Biophysical characterization and antineoplastic activity of new bis(thiosemicarbazonato) Cu(II) complexes

scientific article

Combining imaging and anticancer properties with new heterobimetallic Pt(ii)/M(i) (M = Re, 99mTc) complexes

scientific article published on 6 February 2017

Copper(II) Complexes of Phenanthroline and Histidine Containing Ligands: Synthesis, Characterization and Evaluation of their DNA Cleavage and Cytotoxic Activity

scientific article published on 7 November 2016

Copper(II) complexes with tridentate pyrazole-based ligands: synthesis, characterization, DNA cleavage activity and cytotoxicity

scientific article published on 26 January 2011

Cytotoxic gold compounds: synthesis, biological characterization and investigation of their inhibition properties of the zinc finger protein PARP-1.

scientific article published on 31 January 2012

Design and biological evaluation of new platinum(II) complexes bearing ligands with DNA-targeting ability

scientific article

Enhanced Cytotoxicity and Reactivity of a Novel Platinum(IV) Family with DNA-Targeting Naphthalimide Ligands

scientific article

Establishment and characterization of a novel polarized MDCK epithelial cellular model for CFTR studies.

scientific article published on January 2005

Evaluation of Acridine Orange Derivatives as DNA-Targeted Radiopharmaceuticals for Auger Therapy: Influence of the Radionuclide and Distance to DNA

scientific article

Evaluation of cellular uptake, cytotoxicity and cellular ultrastructural effects of heteroleptic oxidovanadium(IV) complexes of salicylaldimines and polypyridyl ligands

scientific article published on 9 November 2016

Immunohistochemistry of CFTR in native tissues and primary epithelial cell cultures.

scientific article published in August 2004

Impact of the cystic fibrosis mutation F508del-CFTR on renal cyst formation and growth

scientific article published on 08 August 2012

Improved Fmoc-solid-phase peptide synthesis of an extracellular loop of CFTR for antibody selection by the phage display technology

scientific article published on 12 May 2020

In Vivo Pretargeting Based on Cysteine-Selective Antibody Modification with IEDDA Bioorthogonal Handles for Click Chemistry

scientific article published on 09 December 2020

Iron and copper complexes with antioxidant activity as inhibitors of the metastatic potential of glioma cells

scientific article published on 30 March 2020

Isostructural Re(i)/99mTc(i) tricarbonyl complexes for cancer theranostics

scientific article published on 01 May 2015

Metal-Based Inhibition of Poly(ADP-ribose) Polymerase − The Guardian Angel of DNA ⬇️

scientific article published on March 3, 2011

Metalloprobes for functional monitoring of tumour multidrug resistance by nuclear imaging

scientific article published on 07 March 2011

Mono- and dicationic Re(I)/(99m)Tc(I) tricarbonyl complexes for the targeting of energized mitochondria

scientific article published on 26 February 2013

New ternary bipyridine–terpyridine copper(ii) complexes as self-activating chemical nucleases

scholarly article in RSC Advances, vol. 4 no. 106, 2014

Nonconventionaltrans-Platinum Complexes Functionalized with RDG Peptides: Chemical and Cytototoxicity Studies

Novel heterobimetallic radiotheranostic: preparation, activity, and biodistribution

scientific article published on 21 January 2014

Novel structures of platinum complexes bearing N‑bisphosphonates and study of their biological properties

scientific article published on 18 November 2018

Prolonged treatment of cells with genistein modulates the expression and function of the cystic fibrosis transmembrane conductance regulator.

scientific article published on 28 January 2008

Pt(II) complexes with bidentate and tridentate pyrazolyl-containing chelators: synthesis, structural characterization and biological studies.

scientific article published on 21 April 2011

Radiobiological Characterization of CuCl₂ as a Simple Tool for Prostate Cancer Theranostics

scientific article published on 11 November 2018

Radiohalogenated 4-anilinoquinazoline-based EGFR-TK inhibitors as potential cancer imaging agents

scientific article

Re and Tc tricarbonyl complexes: from the suppression of NO biosynthesis in macrophages to in vivo targeting of inducible nitric oxide synthase.

scientific article published on 2 November 2010

Re(I) and Tc(I) complexes for targeting nitric oxide synthase: influence of the chelator in the affinity for the enzyme.

scientific article

S-nitrosoglutathione increases cystic fibrosis transmembrane regulator maturation.

scientific article

Studies of the myocardial uptake and excretion mechanisms of a novel 99mTc heart perfusion agent ⬇️

scientific article published on November 12, 2011

Study of the synthesis, antiproliferative properties, and interaction with DNA and polynucleotides of cisplatin-like Pt(II) complexes containing carcinogenic polyaromatic amines.

scientific article published on 20 July 2013

Synthesis and biological studies of pyrazolyl-diamine Pt(II) complexes containing polyaromatic DNA-binding groups

scientific article

Synthesis, characterization and biological evaluation of (99m)Tc/Re-tricarbonyl quinolone complexes

scientific article published on 21 December 2015

Targeting of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Protein with a Technetium-99m Imaging Probe

scientific article published on 12 June 2018

Technetium-99m complexes of l-arginine derivatives for targeting amino acid transporters

scientific article published on 14 June 2017

The human DnaJ homologue (Hdj)-1/heat-shock protein (Hsp) 40 co-chaperone is required for the in vivo stabilization of the cystic fibrosis transmembrane conductance regulator by Hsp70

scientific article

Tricarbonyl M(I) (M = Re, (99m)Tc) complexes bearing acridine fluorophores: synthesis, characterization, DNA interaction studies and nuclear targeting

scientific article published on 20 July 2010

Unravelling the antitumoral potential of novel bis(thiosemicarbazonato) Zn(II) complexes: structural and cellular studies

scientific article published on 24 November 2018

Unusually common cystic fibrosis mutation in Portugal encodes a misprocessed protein.

scientific article published on November 2003

[(Cp-R)M(CO)3] (M=Re or 99mTc) Arylsulfonamide, arylsulfamide, and arylsulfamate conjugates for selective targeting of human carbonic anhydrase IX

scientific article

[RuII(η⁵-C₅H₅)(bipy)(PPh₃)]⁺, a promising large spectrum antitumor agent: cytotoxic activity and interaction with human serum albumin.

scientific article

List of works by Filipa Mendes

99mTc(I)/Re(I) tricarbonyl complexes for in vivo targeting of melanotic melanoma: Synthesis and biological evaluation

A Multifunctional Radiotheranostic Agent for Dual Targeting of Breast Cancer Cells

A comparison of 14 antibodies for the biochemical detection of the cystic fibrosis transmembrane conductance regulator protein.

Anthracene-terpyridine metal complexes as new G-quadruplex DNA binders.

Antibodies for CFTR studies.

Anticancer activity of structurally related ruthenium(II) cyclopentadienyl complexes

Application of microwave-assisted heating to the synthesis of Pt(II) complexes

Assessment of CFTR localisation in native airway epithelial cells obtained by nasal brushing.

BAG-1 stabilizes mutant F508del-CFTR in a ubiquitin-like-domain-dependent manner

Biophysical characterization and antineoplastic activity of new bis(thiosemicarbazonato) Cu(II) complexes

Combining imaging and anticancer properties with new heterobimetallic Pt(ii)/M(i) (M = Re, 99mTc) complexes

Copper(II) Complexes of Phenanthroline and Histidine Containing Ligands: Synthesis, Characterization and Evaluation of their DNA Cleavage and Cytotoxic Activity

Copper(II) complexes with tridentate pyrazole-based ligands: synthesis, characterization, DNA cleavage activity and cytotoxicity

Cytotoxic gold compounds: synthesis, biological characterization and investigation of their inhibition properties of the zinc finger protein PARP-1.

Design and biological evaluation of new platinum(II) complexes bearing ligands with DNA-targeting ability

Enhanced Cytotoxicity and Reactivity of a Novel Platinum(IV) Family with DNA-Targeting Naphthalimide Ligands

Establishment and characterization of a novel polarized MDCK epithelial cellular model for CFTR studies.

Evaluation of Acridine Orange Derivatives as DNA-Targeted Radiopharmaceuticals for Auger Therapy: Influence of the Radionuclide and Distance to DNA

Evaluation of cellular uptake, cytotoxicity and cellular ultrastructural effects of heteroleptic oxidovanadium(IV) complexes of salicylaldimines and polypyridyl ligands

Immunohistochemistry of CFTR in native tissues and primary epithelial cell cultures.

Impact of the cystic fibrosis mutation F508del-CFTR on renal cyst formation and growth

Improved Fmoc-solid-phase peptide synthesis of an extracellular loop of CFTR for antibody selection by the phage display technology

In Vivo Pretargeting Based on Cysteine-Selective Antibody Modification with IEDDA Bioorthogonal Handles for Click Chemistry

Iron and copper complexes with antioxidant activity as inhibitors of the metastatic potential of glioma cells

Isostructural Re(i)/99mTc(i) tricarbonyl complexes for cancer theranostics

Metal-Based Inhibition of Poly(ADP-ribose) Polymerase − The Guardian Angel of DNA ⬇️

Metalloprobes for functional monitoring of tumour multidrug resistance by nuclear imaging

Mono- and dicationic Re(I)/(99m)Tc(I) tricarbonyl complexes for the targeting of energized mitochondria

New ternary bipyridine–terpyridine copper(ii) complexes as self-activating chemical nucleases

Nonconventionaltrans-Platinum Complexes Functionalized with RDG Peptides: Chemical and Cytototoxicity Studies

Novel heterobimetallic radiotheranostic: preparation, activity, and biodistribution

Novel structures of platinum complexes bearing N‑bisphosphonates and study of their biological properties

Prolonged treatment of cells with genistein modulates the expression and function of the cystic fibrosis transmembrane conductance regulator.

Pt(II) complexes with bidentate and tridentate pyrazolyl-containing chelators: synthesis, structural characterization and biological studies.

Radiobiological Characterization of CuCl₂ as a Simple Tool for Prostate Cancer Theranostics

Radiohalogenated 4-anilinoquinazoline-based EGFR-TK inhibitors as potential cancer imaging agents

Re and Tc tricarbonyl complexes: from the suppression of NO biosynthesis in macrophages to in vivo targeting of inducible nitric oxide synthase.

Re(I) and Tc(I) complexes for targeting nitric oxide synthase: influence of the chelator in the affinity for the enzyme.

S-nitrosoglutathione increases cystic fibrosis transmembrane regulator maturation.

Studies of the myocardial uptake and excretion mechanisms of a novel 99mTc heart perfusion agent ⬇️

Study of the synthesis, antiproliferative properties, and interaction with DNA and polynucleotides of cisplatin-like Pt(II) complexes containing carcinogenic polyaromatic amines.

Synthesis and biological studies of pyrazolyl-diamine Pt(II) complexes containing polyaromatic DNA-binding groups

Synthesis, characterization and biological evaluation of (99m)Tc/Re-tricarbonyl quinolone complexes

Targeting of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Protein with a Technetium-99m Imaging Probe

Technetium-99m complexes of l-arginine derivatives for targeting amino acid transporters

The human DnaJ homologue (Hdj)-1/heat-shock protein (Hsp) 40 co-chaperone is required for the in vivo stabilization of the cystic fibrosis transmembrane conductance regulator by Hsp70

Tricarbonyl M(I) (M = Re, (99m)Tc) complexes bearing acridine fluorophores: synthesis, characterization, DNA interaction studies and nuclear targeting

Unravelling the antitumoral potential of novel bis(thiosemicarbazonato) Zn(II) complexes: structural and cellular studies

Unusually common cystic fibrosis mutation in Portugal encodes a misprocessed protein.

[(Cp-R)M(CO)3] (M=Re or 99mTc) Arylsulfonamide, arylsulfamide, and arylsulfamate conjugates for selective targeting of human carbonic anhydrase IX

[RuII(η⁵-C₅H₅)(bipy)(PPh₃)]⁺, a promising large spectrum antitumor agent: cytotoxic activity and interaction with human serum albumin.