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List of works by Razelle Kurzrock

A First-in-Human Study of Conatumumab in Adult Patients with Advanced Solid Tumors ⬇️

scientific article published on October 14, 2010

A Multicenter Phase I Trial of PX-866, an Oral Irreversible Phosphatidylinositol 3-Kinase Inhibitor, in Patients with Advanced Solid Tumors ⬇️

scientific article published on June 12, 2012

A Phase I Trial of the VEGF Receptor Tyrosine Kinase Inhibitor Pazopanib in Combination with the MEK Inhibitor Trametinib in Advanced Solid Tumors and Differentiated Thyroid Cancers

scientific article published on 11 June 2019

A Phase I, Open-Label Study of Siltuximab, an Anti–IL-6 Monoclonal Antibody, in Patients with B-cell Non-Hodgkin Lymphoma, Multiple Myeloma, or Castleman Disease ⬇️

scientific article published on May 9, 2013

A Phase II Basket Trial of Dual Anti-CTLA-4 and Anti-PD-1 Blockade in Rare Tumors (DART SWOG 1609) in Patients with Nonpancreatic Neuroendocrine Tumors

scientific article published on 22 January 2020

A Tale of Two Histiocytic Disorders ⬇️

scientific article published on January 8, 2013

A cancer trial scandal and its regulatory backlash

scientific article published in January 2014

A comparison of the pharmacokinetics of the anticancer MET inhibitor foretinib free base tablet formulation to bisphosphate salt capsule formulation in patients with solid tumors.

scientific article

A first-in-human study of AMG 208, an oral MET inhibitor, in adult patients with advanced solid tumors

scientific article

A framework for genomic biomarker actionability and its use in clinical decision making

scientific article

A kinase-independent biological activity for insulin growth factor-1 receptor (IGF-1R) : implications for inhibition of the IGF-1R signal

scientific article published on March 2013

A multicenter phase 2 study of the farnesyltransferase inhibitor tipifarnib in intermediate- to high-risk myelodysplastic syndrome

scientific article

A phase 1 dose escalation, pharmacokinetic, and pharmacodynamic evaluation of eIF-4E antisense oligonucleotide LY2275796 in patients with advanced cancer

scientific article published on 10 August 2011

A phase 1 study of gemcitabine combined with dasatinib in patients with advanced solid tumors.

scientific article

A phase 1 study of hepatic arterial infusion of oxaliplatin in combination with systemic 5-fluorouracil, leucovorin, and bevacizumab in patients with advanced solid tumors metastatic to the liver

scientific article

A phase 1b, open-label study of trebananib plus bevacizumab or motesanib in patients with solid tumours

scientific article

A phase 2 randomised discontinuation trial of cabozantinib in patients with ovarian carcinoma

scientific article published on 26 July 2017

A phase 2, open-label, multicenter study of the long-term safety of siltuximab (an anti-interleukin-6 monoclonal antibody) in patients with multicentric Castleman disease

scientific article published on 3 August 2015

A phase I clinical trial of darinaparsin in patients with refractory solid tumors.

scientific article published on 7 July 2009

A phase I dose-finding, safety and tolerability study of AZD8330 in patients with advanced malignancies ⬇️

scientific article published on February 21, 2013

A phase I first-in-human trial of bardoxolone methyl in patients with advanced solid tumors and lymphomas

scientific article

A phase I safety and pharmacokinetic study of the death receptor 5 agonistic antibody PRO95780 in patients with advanced malignancies

scientific article published on 09 February 2010

A phase I study of weekly R1507, a human monoclonal antibody insulin-like growth factor-I receptor antagonist, in patients with advanced solid tumors.

scientific article published on 6 April 2010

A phase I trial of KX2-391, a novel non-ATP competitive substrate-pocket- directed SRC inhibitor, in patients with advanced malignancies

scientific article

A phase I trial of combination trastuzumab, lapatinib, and bevacizumab in patients with advanced cancer

scientific article

A phase I trial of imexon, a pro-oxidant, in combination with docetaxel for the treatment of patients with advanced breast, non-small cell lung and prostate cancer.

scientific article published on 6 June 2009

A phase I trial of liposomal doxorubicin, bevacizumab, and temsirolimus in patients with advanced gynecologic and breast malignancies

scientific article

A phase I, open-label study of trebananib combined with sorafenib or sunitinib in patients with advanced renal cell carcinoma

scientific article

A phase I/II, multiple-dose, dose-escalation study of siltuximab, an anti-interleukin-6 monoclonal antibody, in patients with advanced solid tumors

scientific article published on 21 February 2014

A pilot study of temsirolimus and body composition

scientific article published on 27 July 2013

A simplified interventional mapping system (SIMS) for the selection of combinations of targeted treatments in non-small cell lung cancer

scientific article

APOBEC-related mutagenesis and neo-peptide hydrophobicity: implications for response to immunotherapy

scientific article published on 24 December 2018

ARID1A alterations function as a biomarker for longer progression-free survival after anti-PD-1/PD-L1 immunotherapy

scientific article published on 01 February 2020

ASO Author Reflections: Circulating Tumor DNA in Peritoneal Carcinomatosis

scientific article published on 12 November 2018

ASO Author Reflections: Prognostic Utility of Pre- and Postoperative Circulating Tumor DNA Liquid Biopsies in Patients with Peritoneal Metastases

scientific article published on 17 April 2020

ATM Mutations in Cancer: Therapeutic Implications

scientific article

AZD9150, a next-generation antisense oligonucleotide inhibitor of STAT3 with early evidence of clinical activity in lymphoma and lung cancer

scientific article

Actionability and precision oncology

scientific article published on 12 September 2015

Actionable mutations in plasma cell-free DNA in patients with advanced cancers referred for experimental targeted therapies

scientific article published in May 2015

Activity of XL184 (Cabozantinib), an Oral Tyrosine Kinase Inhibitor, in Patients With Medullary Thyroid Cancer ⬇️

scientific article published on May 23, 2011

Activity of interferon-alpha and isotretinoin in patients with advanced, refractory lymphoid malignancies

scientific article

Activity of the oral MEK inhibitor trametinib in patients with advanced melanoma: a phase 1 dose-escalation trial ⬇️

scientific article published on July 16, 2012

Adjuvant interferon in high-risk melanoma: end of the era?

scientific article published on 30 November 2009

Advance care planning in patients with cancer referred to a phase I clinical trials program: the MD Anderson Cancer Center experience

scientific article published on 9 July 2012

Advanced gynecologic malignancies treated with a combination of the VEGF inhibitor bevacizumab and the mTOR inhibitor temsirolimus

scientific article

Advanced malignancies treated with a combination of the VEGF inhibitor bevacizumab, anti-EGFR antibody cetuximab, and the mTOR inhibitor temsirolimus

scientific article published on 24 February 2016

Advancing the Scope of Nursing Practice: Hepatic Arterial Catheter Removal ⬇️

scientific article published on 01 October 2011

Afebrile Pneumonia in a Patient With Multicentric Castleman Disease on Siltuximab: Infection Without Fever on Anti-Interleukin-6 Therapy

scientific article published on 02 July 2020

Alisertib in Combination With Weekly Paclitaxel in Patients With Advanced Breast Cancer or Recurrent Ovarian Cancer: A Randomized Clinical Trial

scientific article published on 10 January 2019

An 84-Year-Old Woman With an Indolent B-Cell Lymphoma

scientific article published on 15 August 2016

An appraisal of drug development timelines in the Era of precision oncology

scientific article published on 13 July 2016

An avatar for precision cancer therapy

scientific article published on 01 November 2018

Anakinra-responsive lichen planus in a woman with Erdheim-Chester disease: a therapeutic enigma

scientific article published on 15 January 2014

Analyses of selected safety endpoints in phase 1 and late-phase clinical trials of anti-PD-1 and PD-L1 inhibitors: prediction of immune-related toxicities

scientific article

Analysis of 1,115 patients tested for MET amplification and therapy response in the MD Anderson Phase I Clinic.

scientific article published on 17 October 2014

Analysis of Circulating Tumor DNA and Clinical Correlates in Patients with Esophageal, Gastroesophageal Junction and Gastric Adenocarcinoma

scientific article published on 22 October 2018

Analysis of Drug Development Paradigms for Immune Checkpoint inhibitors

scientific article published on 6 December 2017

Analysis of MDM2 Amplification: Next-Generation Sequencing of Patients With Diverse Malignancies

scientific article published on 13 July 2018

Analysis of NTRK Alterations in Pan-Cancer Adult and Pediatric Malignancies: Implications for NTRK-Targeted Therapeutics

scientific article published on 15 November 2018

Analysis of Tissue and Circulating Tumor DNA by Next-Generation Sequencing of Hepatocellular Carcinoma: Implications for Targeted Therapeutics

scientific article published on 26 February 2018

Analysis of long-term outcomes of combined modality therapy for cutaneous T-cell lymphoma

scientific article published in July 2003

Anastrozole and everolimus in advanced gynecologic and breast malignancies: activity and molecular alterations in the PI3K/AKT/mTOR pathway

scientific article

Androgen receptors beyond prostate cancer: an old marker as a new target

scientific article

Angiosarcoma heterogeneity and potential therapeutic vulnerability to immune checkpoint blockade: insights from genomic sequencing

scientific article published on 09 July 2020

Anti-vascular endothelial growth factor therapies and cardiovascular toxicity: what are the important clinical markers to target?

scientific article published on 05 February 2010

Anticoagulation-induced severe bleeding in a patient receiving bevacizumab therapy ⬇️

scientific article published on December 15, 2011

Appearance of New Cutaneous Superficial Basal Cell Carcinomas during Successful Nivolumab Treatment of Refractory Metastatic Disease: Implications for Immunotherapy in Early Versus Late Disease

scientific article published on 31 July 2017

Assessing PIK3CA and PTEN in early-phase trials with PI3K/AKT/mTOR inhibitors

scientific article published on 16 January 2014

Association of Biomarker-Based Treatment Strategies With Response Rates and Progression-Free Survival in Refractory Malignant Neoplasms: A Meta-analysis

scientific article

Association of concurrent acid-suppression therapy with survival outcomes and adverse event incidence in oncology patients receiving erlotinib

scientific article published on 2 July 2016

Attrition of Patients on a Precision Oncology Trial: Analysis of the I-PREDICT Experience

scientific article published on 19 September 2020

Aurora Kinase Inhibitors in Oncology Clinical Trials: Current State of the Progress

scientific article

Autocrine interleukin-6 production in renal cell carcinoma: evidence for the involvement of p53

scientific article published on 01 February 2002

Autophagy as a target for anticancer therapy

scientific article published on 17 May 2011

BAP1: Not just a BRCA1-associated protein

scientific article published on 20 August 2020

BRAF Mutation Testing in Cell-Free DNA from the Plasma of Patients with Advanced Cancers Using a Rapid, Automated Molecular Diagnostics System

scientific article published on 20 May 2016

BRAF V600E mutations in urine and plasma cell-free DNA from patients with Erdheim-Chester disease

scientific article

BRAF inhibitor dabrafenib in patients with metastatic BRAF-mutant thyroid cancer

scientific article

BRAF mutation as a novel driver of eosinophilic cystitis

scientific article published on 22 August 2017

BRAF mutation testing with a rapid, fully integrated molecular diagnostics system

scientific article

BRAF mutations in advanced cancers: clinical characteristics and outcomes

scientific article (publication date: 2011)

BRAF(V600) Inhibitor GSK2118436 Targeted Inhibition of Mutant BRAF in Cancer Patients Does Not Impair Overall Immune Competency ⬇️

scientific article published on February 21, 2012

Barriers to study enrollment in patients with advanced cancer referred to a phase I clinical trials unit

scientific article published on 23 October 2013

Basal Cell Carcinoma: Management of Advanced or Metastatic Cancer with Checkpoint Inhibitors and Concurrent Paradoxical Development of New Superficial Tumors

scientific article published on 25 February 2020

Bevacizumab-based treatment in colorectal cancer with a NRAS Q61K mutation ⬇️

scientific article published on February 12, 2013

Beyond conventional chemotherapy: Emerging molecular targeted and immunotherapy strategies in urothelial carcinoma

scientific article published on 23 June 2015

Binding partners for curcumin in human schwannoma cells: biologic implications

scientific article

Biomarker-directed therapy of squamous carcinomas of the head and neck: targeting PI3K/PTEN/mTOR pathway.

scientific article

Body composition, symptoms, and survival in advanced cancer patients referred to a phase I service

scientific article

Breast Cancer Experience of the Molecular Tumor Board at the University of California, San Diego Moores Cancer Center

scientific article

Bringing Blood-Based Molecular Testing to the Clinic

scientific article

CASE 1. Langerhans cell histiocytosis of the thyroid

scientific article published in January 2006

CAT scan reveals BAT sign

scientific article

Cancer Therapy Directed by Comprehensive Genomic Profiling: A Single Center Study.

scientific article published on 18 May 2016

Cancer research in the United States: A critical review of current status and proposal for alternative models

scientific article published on 14 May 2018

Cancer: the road to Amiens

scientific article published on 08 December 2008

Cardiac toxicity of alemtuzumab in patients with mycosis fungoides/Sézary syndrome

scientific article published on 8 April 2004

Castleman's Disease: From Basic Mechanisms to Molecular Therapeutics ⬇️

scientific article published on March 25, 2011

Castleman's disease and sarcoidosis, a rare association resulting in a "mixed" response: a case report

scientific article published on 28 February 2015

Cell-Cycle Gene Alterations in 4,864 Tumors Analyzed by Next-Generation Sequencing: Implications for Targeted Therapeutics

scientific article

Cell-Free DNA from Ascites and Pleural Effusions: Molecular Insights into Genomic Aberrations and Disease Biology

scientific article published in May 2017

Cetuximab-associated elongation of the eyelashes: case report and review of eyelash trichomegaly secondary to epidermal growth factor receptor inhibitors

scientific article published on February 2011

Challenges and perspective of drug repurposing strategies in early phase clinical trials

scientific article published on 30 June 2015

Challenging Standard-of-Care Paradigms in the Precision Oncology Era.

scientific article published on 12 January 2018

Change in tumor size by RECIST correlates linearly with overall survival in phase I oncology studies

scientific article

Characteristics and survival of patients with advanced cancer and p53 mutations

scientific article

Chemotherapy resistance and retreatment: a dogma revisited

scientific article published on 01 April 2010

Circulating Tumor Cells: From the Laboratory to the Cancer Clinic

scientific article published on 21 August 2020

Click chemistry, 3D-printing, and omics: the future of drug development

scientific article

Clinical characteristics and outcomes of pediatric oncology patients with aggressive biology enrolled in phase I clinical trials designed for adults: the university of Texas MD anderson cancer center experience

scientific article

Clinical correlates of blood-derived circulating tumor DNA in pancreatic cancer

scientific article published on 04 December 2019

Clinical development of farnesyltransferase inhibitors in leukemias and myelodysplastic syndrome

scientific article

Clinical implications of plasma circulating tumor DNA in gynecologic cancer patients

scientific article published on 03 September 2020

Clinical outcomes and factors predicting development of venous thromboembolic complications in patients with advanced refractory cancer in a Phase I Clinic: the M. D. Anderson Cancer Center experience

scientific article published on 01 July 2009

Clinical outcomes of patients with breast cancer in a phase I clinic: the M. D. Anderson cancer center experience

scientific article published in February 2010

Clinical pharmacodynamic/exposure characterisation of the multikinase inhibitor ilorasertib (ABT-348) in a phase 1 dose-escalation trial.

scientific article

Combined BRAF and MEK Inhibition With Dabrafenib and Trametinib in BRAF V600-Mutant Colorectal Cancer.

scientific article

Combining curcumin (diferuloylmethane) and heat shock protein inhibition for neurofibromatosis 2 treatment: analysis of response and resistance pathways

scientific article

Combining erlotinib and cetuximab is associated with activity in patients with non-small cell lung cancer (including squamous cell carcinomas) and wild-type EGFR or resistant mutations

scientific article

Combining targeted therapies: practical issues to consider at the bench and bedside

scientific article published on 15 January 2010

Community-acquired methicillin-resistant Staphylococcus aureus skin infection: an emerging clinical problem

scientific article

Comparative Effectiveness of an mTOR-Based Systemic Therapy Regimen in Advanced, Metaplastic and Nonmetaplastic Triple-Negative Breast Cancer

scientific article published on 23 August 2018

Compliance in Early-Phase Cancer Clinical Trials Research ⬇️

scientific article published on January 1, 2013

Comprehensive Genomic Landscape and Precision Therapeutic Approach in Biliary Tract Cancers

scientific article published on 23 July 2020

Comprehensive Genomic Profiling Reveals Diverse but Actionable Molecular Portfolios across Hematologic Malignancies: Implications for Next Generation Clinical Trials

scientific article published on 21 December 2018

Computed axial tomography scanning (CT scan).

scientific article published in October 2006

Concordance between TP53 alterations in blood and tissue: impact of time interval, biopsy site, cancer type and circulating tumor DNA burden

scientific article published on 18 March 2020

Consensus recommendations to accelerate clinical trials for neurofibromatosis type 2.

scientific article

Core Clinical Data Elements for Cancer Genomic Repositories: A Multi-stakeholder Consensus

scientific article published in November 2017

Counterpoint: Successes in the Pursuit of Precision Medicine: Biomarkers Take Credit

scientific article published on 01 July 2017

Curcumin (diferuloylmethane) alters the expression profiles of microRNAs in human pancreatic cancer cells

scientific article

Curcumin-induced antiproliferative and proapoptotic effects in melanoma cells are associated with suppression of IkappaB kinase and nuclear factor kappaB activity and are independent of the B-Raf/mitogen-activated/extracellular signal-regulated prot

scientific article published on August 2005

Cutaneous Castleman disease ⬇️

scientific article published on April 26, 2012

Cutaneous castleman's disease responds to anti interleukin-6 treatment

scientific article

Cyclin Pathway Genomic Alterations Across 190,247 Solid Tumors: Leveraging Large-Scale Data to Inform Therapeutic Directions

scientific article published on 04 September 2020

Cyclin alterations in diverse cancers: Outcome and co-amplification network

scientific article published on February 2015

Cyclin-dependent kinase pathway aberrations in diverse malignancies: clinical and molecular characteristics

scientific article

Cytokine genes and pain severity in lung cancer: exploring the influence of TNF-alpha-308 G/A IL6-174G/C and IL8-251T/A.

scientific article published in December 2007

Cytokines in pancreatic carcinoma: correlation with phenotypic characteristics and prognosis

scientific article published on 01 December 2004

Dabrafenib in patients with melanoma, untreated brain metastases, and other solid tumours: a phase 1 dose-escalation trial.

scientific article

Debunking the Delusion That Precision Oncology Is an Illusion

scientific article published on 26 May 2017

Decitabine effect on tumor global DNA methylation and other parameters in a phase I trial in refractory solid tumors and lymphomas.

scientific article published on 26 May 2009

Decitabine impact on the endocytosis regulator RhoA, the folate carriers RFC1 and FOLR1, and the glucose transporter GLUT4 in human tumors

scientific article published on 09 January 2014

Detection rate of actionable mutations in diverse cancers using a biopsy-free (blood) circulating tumor cell DNA assay

scientific article published on February 2016

Determination of minimum effective dose and optimal dosing schedule for liposomal curcumin in a xenograft human pancreatic cancer model.

scientific article

Development of 2 Bromodomain and Extraterminal Inhibitors With Distinct Pharmacokinetic and Pharmacodynamic Profiles for the Treatment of Advanced Malignancies

scientific article published on 16 September 2019

Development of curcumin as an epigenetic agent

scientific article published on October 2010

Distinct biological impact of dephosphorylation vs. downregulation of p210Bcr-Abl: implications for imatinib mesylate response and resistance

scientific article published on August 2006

Dodging a dogma: is treating beyond progression beneficial? ⬇️

scientific article published on February 27, 2013

Dose selection, pharmacokinetics, and pharmacodynamics of BRAF inhibitor dabrafenib (GSK2118436).

scientific article published on 23 June 2014

Dose-finding study of hepatic arterial infusion of irinotecan-based treatment in patients with advanced cancers metastatic to the liver

scientific article

Dose-finding study of hepatic arterial infusion of oxaliplatin-based treatment in patients with advanced solid tumors metastatic to the liver

scientific article published on 11 November 2012

Dosing Oncology Therapeutics in Combination Therapy for Renal Dysfunction: The University of California San Diego Study of Personalized Cancer Therapy to Determine Response and Toxicity (UCSD-PREDICT) Experience

scientific article published on 26 November 2018

Dosing Three-Drug Combinations That Include Targeted Anti-Cancer Agents: Analysis of 37,763 Patients.

scientific article published on 19 April 2017

Dosing de novo combinations of two targeted drugs: Towards a customized precision medicine approach to advanced cancers

scientific article published on 25 January 2016

Dosing immunotherapy combinations: Analysis of 3,526 patients for toxicity and response patterns

scientific article published on 28 June 2017

Dosing targeted and cytotoxic two-drug combinations: Lessons learned from analysis of 24,326 patients reported 2010 through 2013.

scientific article published on 8 July 2016

Dual Checkpoint Blockade in a Neuroendocrine Carcinoma With Dual PD-L1/PD-L2 Amplification and High Tumor Mutational Burden

scientific article published on 15 May 2020

Dual EGFR blockade with cetuximab and erlotinib combined with anti-VEGF antibody bevacizumab in advanced solid tumors: a phase 1 dose escalation triplet combination trial

scientific article published on 20 April 2020

Dual EGFR inhibition in combination with anti-VEGF treatment in colorectal cancer

scientific article

Dual EGFR inhibition in combination with anti-VEGF treatment: a phase I clinical trial in non-small cell lung cancer

scientific article published on January 2013

Dual antiangiogenic inhibition: a phase I dose escalation and expansion trial targeting VEGF-A and VEGFR in patients with advanced solid tumors

scientific article published on 4 November 2014

Dual inhibition of the vascular endothelial growth factor pathway: a phase 1 trial evaluating bevacizumab and AZD2171 (cediranib) in patients with advanced solid tumors

scientific article

Early drug development of inhibitors of the insulin-like growth factor-I receptor pathway: lessons from the first clinical trials

scientific article

Effect of Dual Vascular Input Functions on CT Perfusion Parameter Values and Reproducibility in Liver Tumors and Normal Liver ⬇️

scientific article published on July 1, 2012

Effect of Food on the Pharmacokinetics of the Investigational Aurora A Kinase Inhibitor Alisertib (MLN8237) in Patients with Advanced Solid Tumors

scientific article

Effect of Sampling Frequency on Perfusion Values in Perfusion CT of Lung Tumors ⬇️

scientific article published on February 1, 2013

Effect of duration of scan acquisition on CT perfusion parameter values in primary and metastatic tumors in the lung ⬇️

scientific article published on June 13, 2013

Effects of patupilone on the pharmacokinetics and pharmacodynamics of warfarin in patients with advanced malignancies: a phase I clinical trial

scientific article

Efficacy and safety of anticancer drug combinations: a meta-analysis of randomized trials with a focus on immunotherapeutics and gene-targeted compounds

scientific article published on 13 January 2020

Efficacy of the farnesyl transferase inhibitor R115777 in chronic myeloid leukemia and other hematologic malignancies

scientific article published on 31 October 2002

Electronic clinical challenges and images in GI. Image 2. Extensive bilateral extracranial subcutaneous fluid collection

scientific article published on 08 May 2009

Epidermal growth factor receptor mutation and diverse tumors: case report and concise literature review

scientific article published on 07 March 2010

Epstein-Barr virus and cancer

scientific article

Epstein-Barr virus in patients with chronic lymphocytic leukemia: a pilot study

scientific article published in May 2006

Equipoise lost: ethics, costs, and the regulation of cancer clinical research

scientific article published on 20 April 2010

Erdheim-Chester disease: characteristics and management

scientific article published on 09 May 2014

Erratum to: Pharmacokinetic evaluation of nanoparticle albumin-bound paclitaxel delivered via hepatic arterial infusion in patients with predominantly hepatic metastases

scientific article published on 01 April 2016

Erratum: Actionable mutations in plasma cell-free DNA in patients with advanced cancers referred for experimental targeted therapies

scientific article published in September 2015

Evaluation of a novel blood pressure scoring method and its association with clinical response in cancer patients treated with anti-vascular endothelial growth factor therapy

scientific article published on 26 April 2014

Evaluation of liposomal curcumin cytochrome p450 metabolism

scientific article published in March 2010

Evaluation of the clinical relevance of body composition parameters in patients with cancer metastatic to the liver treated with hepatic arterial infusion chemotherapy

scientific article published on 09 January 2012

Ewing's sarcoma: overcoming the therapeutic plateau

scientific article published on June 2012

Exceptional Response to Nivolumab and Stereotactic Body Radiation Therapy (SBRT) in Neuroendocrine Cervical Carcinoma with High Tumor Mutational Burden: Management Considerations from the Center For Personalized Cancer Therapy at UC San Diego Moores

scientific article published on 26 May 2017

Exploratory study of carboplatin plus the copper-lowering agent trientine in patients with advanced malignancies

scientific article published on 5 December 2013

Exploratory study of hepatic arterial infusion oxaliplatin with systemic 5-fluorouracil/bevacizumab in patients with refractory solid tumor and extensive liver metastases

scientific article

Exploring response signals and targets in aggressive unresectable hepatocellular carcinoma: an analysis of targeted therapy phase 1 trials

scientific article

Exploring the Benefit/Risk Associated with Antiangiogenic Agents for the Treatment of Non-Small Cell Lung Cancer Patients

scientific article published on 9 December 2016

Expression of TIM3/VISTA checkpoints and the CD68 macrophage-associated marker correlates with anti-PD1/PDL1 resistance: implications of immunogram heterogeneity

scientific article published on 17 February 2020

Eyelash trichomegaly: review of congenital, acquired, and drug‐associated etiologies for elongation of the eyelashes ⬇️

scientific article published on June 1, 2012

FGFR1 and NTRK3 actionable alterations in "Wild-Type" gastrointestinal stromal tumors

scientific article published on 14 December 2016

Factors associated with failure of oncology drugs in late-stage clinical development: A systematic review

scientific article published on 4 November 2016

Factors related to biopsy willingness in patients with advanced cancer in a phase 1 clinic for molecularly targeted therapy ⬇️

scientific article published on March 2, 2013

Farnesyltransferase inhibitor R115777 in myelodysplastic syndrome: clinical and biologic activities in the phase 1 setting

scientific article published on 28 August 2003

Farnesyltransferase inhibitors

scientific article published on 01 March 2005

Farnesyltransferase inhibitors: novel compounds in development for the treatment of myeloid malignancies

scientific article

Farnesyltransferase inhibitors: where are we now?

scientific article

Fibroblast growth factor receptor signaling in hereditary and neoplastic disease: biologic and clinical implications

scientific article (publication date: September 2015)

First-in-Human Phase I Study of GSK2126458, an Oral Pan-Class I Phosphatidylinositol-3-Kinase Inhibitor, in Patients with Advanced Solid Tumor Malignancies

scientific article

First-in-Man Phase I Trial of the Selective MET Inhibitor Tepotinib in Patients with Advanced Solid Tumors

scientific article published on 10 December 2019

Fool’s gold, lost treasures, and the randomized clinical trial ⬇️

scientific article published on April 16, 2013

From Tissue-Agnostic to N-of-One Therapies: (R)Evolution of the Precision Paradigm

scientific article published on 29 September 2020

Future clinical implications for farnesyltransferase inhibitors in hematologic malignancies

scientific article

GNAS, GNAQ, and GNA11 Alterations in Patients With Diverse Cancers

scientific article published on 11 September 2018

Genetic and nongenetic covariates of pain severity in patients with adenocarcinoma of the pancreas: assessing the influence of cytokine genes

scientific article published on December 2009

Genetics on a WHIM.

scientific article published on 20 September 2013

Genome-Wide Sequencing of Cell-Free DNA Identifies Copy-Number Alterations That Can Be Used for Monitoring Response to Immunotherapy in Cancer Patients

scientific article published on 06 December 2018

Genomic Alterations in Circulating Tumor DNA from Diverse Cancer Patients Identified by Next-Generation Sequencing

scientific article published on 14 August 2017

Genomic Assessment of Blood-Derived Circulating Tumor DNA in Patients With Colorectal Cancers: Correlation With Tissue Sequencing, Therapeutic Response, and Survival

Genomic Landscape of Malignant Mesotheliomas

scientific article published on 9 August 2016

Genomic Profiling of Blood-Derived Circulating Tumor DNA from Patients with Colorectal Cancer: Implications for Response and Resistance to Targeted Therapeutics

scientific article published on 18 July 2019

Genomic Profiling of Cancers of Unknown Primary Site: The Next Steps

scientific article

Genomic and transcriptomic profiling expands precision cancer medicine: the WINTHER trial

scientific article published on 22 April 2019

Genomic landscape of advanced basal cell carcinoma: Implications for precision treatment with targeted and immune therapies

scientific article published on 22 December 2017

Genomic landscape of salivary gland tumors

scientific article

Genomic portfolio of Merkel cell carcinoma as determined by comprehensive genomic profiling: implications for targeted therapeutics

scientific article published on 10 March 2016

Genomically Driven Tumors and Actionability across Histologies: BRAF-Mutant Cancers as a Paradigm

scientific article published on 23 March 2016

Genomics of Immunotherapy-Associated Hyperprogressors-Response

scientific article

Genomics of gallbladder cancer: the case for biomarker-driven clinical trial design

scientific article published on 09 February 2016

Germline PTPRD mutations in Ewing sarcoma: biologic and clinical implications

scientific article published on June 2013

HER2 aberrations in cancer: implications for therapy

scientific article

HER2 expression status in diverse cancers: review of results from 37,992 patients

scientific article

Health policy: The right to try is embodied in the right to die.

scientific article

Hepatic arterial infusion chemotherapy for metastatic colorectal cancer: a concise overview

scientific article published in August 2004

Hepatic arterial infusion therapy in advanced cancer and liver-predominant disease: the MD Anderson Experience

scientific article published in October 2013

High Tumor Mutational Burden Correlates with Longer Survival in Immunotherapy-Naïve Patients with Diverse Cancers

scientific article published on 03 August 2020

High expression of PD-1 ligands is associated with kataegis mutational signature and APOBEC3 alterations

scientific article published on 31 January 2017

Human epidermal receptor 2–amplified salivary duct carcinoma: Regression with dual human epidermal receptor 2 inhibition and anti–vascular endothelial growth factor combination treatment ⬇️

scientific article published on October 19, 2013

Hybrid capture-based genomic profiling of circulating tumor DNA from patients with advanced cancers of the gastrointestinal tract or anus.

scientific article published on 23 January 2018

Hypermutated Circulating Tumor DNA: Correlation with Response to Checkpoint Inhibitor-Based Immunotherapy

scientific article

Hyperprogression and Immune Checkpoint Inhibitors: Hype or Progress?

scientific article published on 20 November 2019

Hyperprogressors after Immunotherapy: Analysis of Genomic Alterations Associated with Accelerated Growth Rate

scientific article published on 28 March 2017

I have good news! You have leukemia

scientific article published on 01 May 2007

IGF-1R/mTOR Targeted Therapy for Ewing Sarcoma: A Meta-Analysis of Five IGF-1R-Related Trials Matched to Proteomic and Radiologic Predictive Biomarkers

scientific article published on 02 July 2020

Identification of Incidental Germline Mutations in Patients With Advanced Solid Tumors Who Underwent Cell-Free Circulating Tumor DNA Sequencing

scientific article published on 19 October 2018

Identification of novel therapeutic targets in the PI3K/AKT/mTOR pathway in hepatocellular carcinoma using targeted next generation sequencing

scientific article

Identification of targets for prostate cancer immunotherapy

scientific article published on 06 January 2019

Idiopathic multicentric Castleman's disease: a systematic literature review

scientific article published on 17 March 2016

Imatinib-induced postoperative periorbital purpura: GASP (Gleevec-Associated Surgical Purpura) in a woman with imatinib-treated chronic myelogenous leukemia

Immune Escape of AML Cells after Transplantation

scientific article published in March 2019

Immune profiling and immunotherapeutic targets in pancreatic cancer

scientific article

Impact of Precision Medicine in Diverse Cancers: A Meta-Analysis of Phase II Clinical Trials

scientific article published on 24 August 2015

Impact of a Biomarker-Based Strategy on Oncology Drug Development: A Meta-analysis of Clinical Trials Leading to FDA Approval

scientific article published on 15 September 2015

Impact of decitabine on immunohistochemistry expression of the putative tumor suppressor genes FHIT, WWOX, FUS1 and PTEN in clinical tumor samples

scientific article

Impact of p210(Bcr-Abl) on ultraviolet C wavelength-induced DNA damage and repair ⬇️

scientific article published on September 1, 2003

Improving the Institutional Submission and Approval Process for Clinical Research Protocols in Oncology

scientific article published on 01 April 2007

In Reply

Incidence of mucositis in patients treated with temsirolimus-based regimens and correlation to treatment response

scientific article published on 25 March 2014

Increased cancer antigen 27.29 (CA27.29) level in patients with mycosis fungoides

scientific article published in March 2008

Inhibition of the Ras/Raf/MEK/ERK and RET kinase pathways with the combination of the multikinase inhibitor sorafenib and the farnesyltransferase inhibitor tipifarnib in medullary and differentiated thyroid malignancies

scientific article

Initiative for Molecular Profiling and Advanced Cancer Therapy (IMPACT): An MD Anderson Precision Medicine Study

scientific article published on 08 September 2017

Insulin growth factor-receptor (IGF-1R) antibody cixutumumab combined with the mTOR inhibitor temsirolimus in patients with refractory Ewing's sarcoma family tumors

scientific article

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MET alterations detected in blood-derived circulating tumor DNA correlate with bone metastases and poor prognosis.

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MS-275 sensitizes TRAIL-resistant breast cancer cells, inhibits angiogenesis and metastasis, and reverses epithelial-mesenchymal transition in vivo

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Merkel Cell Carcinoma with a Suppressor of Fused (SUFU) Mutation: Case Report and Potential Therapeutic Implications

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Molecular Profiling of Hepatocellular Carcinoma Using Circulating Cell-Free DNA

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Next-Generation Sequencing of Circulating Tumor DNA Reveals Frequent Alterations in Advanced Hepatocellular Carcinoma

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Next-generation sequencing of prostate cancer: genomic and pathway alterations, potential actionability patterns, and relative rate of use of clinical-grade testing

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Novel in vivo imaging shows up-regulation of death receptors by paclitaxel and correlates with enhanced antitumor effects of receptor agonist antibodies

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Phase II evaluation of gemcitabine monotherapy for cutaneous T-cell lymphoma.

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Phase II randomised discontinuation trial of the MET/VEGF receptor inhibitor cabozantinib in metastatic melanoma

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Phenotypic and Genomic Determinants of Immunotherapy Response Associated with Squamousness

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Philadelphia chromosome-positive leukemias: from basic mechanisms to molecular therapeutics

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Phosphatidylinositol 3-kinase pathway genomic alterations in 60,991 diverse solid tumors informs targeted therapy opportunities

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Pilot study of huachansu in patients with hepatocellular carcinoma, nonsmall-cell lung cancer, or pancreatic cancer

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Pilot study of regional, hepatic intra-arterial paclitaxel in patients with breast carcinoma metastatic to the liver

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Polycystic ovary syndrome in men.

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Polycystic ovary syndrome in men: Stein-Leventhal syndrome revisited

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Poor prognosis in non-Caucasian patients with early-onset mycosis fungoides

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Posterior Reversible Encephalopathy Syndrome: More Than Meets the Eye ⬇️

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Pre-treatment endogenous interleukin-1 receptor antagonist (IL-1Ra) levels in metastatic colorectal cancer (mCRC) patients are associated with clinical outcomes after anti-interleukin-1a therapy (MABp1)

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Precision medicine: lessons learned from the SHIVA trial

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Preoperative Circulating Tumor DNA in Patients with Peritoneal Carcinomatosis is an Independent Predictor of Progression-Free Survival

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Prevalence of PDL1 Amplification and Preliminary Response to Immune Checkpoint Blockade in Solid Tumors

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Prevalence of complementary medicine use in a phase 1 clinical trials program: the MD Anderson Cancer Center Experience

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Prevalence of established and emerging biomarkers of immune checkpoint inhibitor response in advanced hepatocellular carcinoma.

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Prognostic Utility of Pre- and Postoperative Circulating Tumor DNA Liquid Biopsies in Patients with Peritoneal Metastases

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Prognostic implications of RAS alterations in diverse malignancies and impact of targeted therapies

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Progression‐free survival 2: Is it ready for prime time?

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Project Zero Delay: a process for accelerating the activation of cancer clinical trials

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Proliferative potential and resistance to immune checkpoint blockade in lung cancer patients

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Proliferative potential and response to nivolumab in clear cell renal cell carcinoma patients

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Promoting Precision Cancer Medicine through a Community-Driven Knowledgebase

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Prospective blinded study of BRAFV600E mutation detection in cell-free DNA of patients with systemic histiocytic disorders

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Purine analogues in advanced T-cell lymphoid malignancies

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R1507, an Anti-Insulin-Like Growth Factor-1 Receptor (IGF-1R) Antibody, and EWS/FLI-1 siRNA in Ewing's Sarcoma: Convergence at the IGF/IGFR/Akt Axis ⬇️

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RE: Meta-analysis of the relationship between dose and benefit in phase I targeted agent trials

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RET Aberrations in Diverse Cancers: Next-Generation Sequencing of 4,871 Patients

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Radiation Therapy Combined With Checkpoint Blockade Immunotherapy for Metastatic Undifferentiated Pleomorphic Sarcoma of the Maxillary Sinus With a Complete Response

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Rare Tumor Clinic: The University of California San Diego Moores Cancer Center Experience with a Precision Therapy Approach

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Razelle Kurzrock and Shumei Kato on Immunotherapy and Hyperprogression of Disease

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Real-world data from a molecular tumor board demonstrates improved outcomes with a precision N-of-One strategy

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Recombinant human soluble tumor necrosis factor (TNF) receptor (p75) fusion protein Enbrel in patients with refractory hematologic malignancies

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Refractory Hodgkin lymphoma responds to pentostatin (2'-deoxycoformycin).

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Remembering the forgotten child: the role of immune checkpoint inhibition in patients with human immunod eficiency virus and cancer

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Reproducibility of perfusion parameters in dynamic contrast-enhanced MRI of lung and liver tumors: effect on estimates of patient sample size in clinical trials and on individual patient responses

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Response of Lymphangioleiomyomatosis to a Mammalian Target of Rapamycin Inhibitor (Temsirolimus) –Based Treatment ⬇️

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Revisiting Epidermal Growth Factor Receptor () Amplification as a Target for Anti-EGFR Therapy: Analysis of Cell-Free Circulating Tumor DNA in Patients With Advanced Malignancies

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STAT3 antisense oligonucleotide AZD9150 in a subset of patients with heavily pretreated lymphoma: results of a phase 1b trial

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SU2C phase Ib study of paclitaxel and MK-2206 in advanced solid tumors and metastatic breast cancer

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Safety, Pharmacokinetics, and Activity of GRN1005, a Novel Conjugate of Angiopep-2, a Peptide Facilitating Brain Penetration, and Paclitaxel, in Patients with Advanced Solid Tumors ⬇️

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Sequential interleukin 3 and granulocyte-macrophage-colony stimulating factor therapy in patients with bone marrow failure with long-term follow-up of responses

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Siltuximab: a targeted therapy for idiopathic multicentric Castleman disease

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Squamousness: Next-generation sequencing reveals shared molecular features across squamous tumor types

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Standardized uptake value (SUVmax) in 18F-FDG PET/CT is correlated with the total number of main oncogenic anomalies in cancer patients

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Successful Treatment of HIV-Associated Kaposi Sarcoma with Immune Checkpoint Blockade

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Successful implementation of genomically based treatment of chemotherapy refractory peripheral T-cell lymphoma (PTCL)

scientific article published on 11 October 2018

Successful treatment of Castleman's disease with interleukin-1 receptor antagonist (Anakinra).

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Successful treatment of Erdheim-Chester disease, a non-Langerhans-cell histiocytosis, with interferon-alpha

scientific article published in November 2005

Sulforaphane inhibits angiogenesis through activation of FOXO transcription factors.

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Survival implications of the relationship between tissue versus circulating tumor DNA TP53 mutations - a perspective from a real-world precision medicine cohort

scientific article published on 30 September 2020

Survival of 1,181 patients in a phase I clinic: the MD Anderson Clinical Center for targeted therapy experience

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Survival of patients in a Phase 1 Clinic: the M. D. Anderson Cancer Center experience

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Sweet's syndrome revisited: a review of disease concepts

scientific article published on October 2003

Sweet's syndrome: a review of current treatment options

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Synergy between VEGF/VEGFR inhibitors and chemotherapy agents in the phase I clinic

scientific article published on 14 October 2014

TP53 Alterations Correlate with Response to VEGF/VEGFR Inhibitors: Implications for Targeted Therapeutics

scientific article published on 27 July 2016

TP53 mutations and number of alterations correlate with maximum standardized uptake value (SUVmax) determined by positron emission tomography/computed tomography (PET/CT) [18F] fluorodeoxyglucose (18F-FDG PET).

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Target validation using Phase 0 clinical trials: Promises and pitfalls

scientific article published on 01 November 2009

Target-based therapeutic matching in early-phase clinical trials in patients with advanced colorectal cancer and PIK3CA mutations

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Targeted Inhibitors: Novel Strategies for Response Optimization.

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Targeted PI3K/AKT/mTOR therapy for metastatic carcinomas of the cervix: A phase I clinical experience

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Targeted Therapy for Advanced Solid Tumors on the Basis of Molecular Profiles: Results From MyPathway, an Open-Label, Phase IIa Multiple Basket Study

scientific article published on 10 January 2018

Targeted morphoproteomic profiling of Ewing's sarcoma treated with insulin-like growth factor 1 receptor (IGF1R) inhibitors: response/resistance signatures

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Targeted therapies: What have we learned from SHIVA?

scientific article published on 11 October 2016

Targeted therapy for genetic cancer syndromes: Von Hippel-Lindau disease, Cowden syndrome, and Proteus syndrome

scientific article published on February 2015

Targeted therapy for hereditary cancer syndromes: hereditary breast and ovarian cancer syndrome, Lynch syndrome, familial adenomatous polyposis, and Li-Fraumeni syndrome

scientific article published on December 2014

Targeted therapy for hereditary cancer syndromes: neurofibromatosis type 1, neurofibromatosis type 2, and Gorlin syndrome.

scientific article published on December 2014

Targeted therapy in non-small-cell lung cancer--is it becoming a reality?

scientific article published on 15 June 2010

Targeted therapy in rare cancers—adopting the orphans ⬇️

scientific article published on September 11, 2012

Targeted therapy of advanced gallbladder cancer and cholangiocarcinoma with aggressive biology: eliciting early response signals from phase 1 trials

scientific article published on January 2013

Targeting fusions for improved outcomes in oncology treatment

scientific article published on 03 December 2019

Targeting hypoxia-inducible factor-1α (HIF-1α) in combination with antiangiogenic therapy: a phase I trial of bortezomib plus bevacizumab

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Targeting the Apoptotic Pathway in Chondrosarcoma Using Recombinant Human Apo2L/TRAIL (Dulanermin), a Dual Proapoptotic Receptor (DR4/DR5) Agonist ⬇️

scientific article published on August 20, 2012

Targeting the PI3K/AKT/mTOR Pathway for the Treatment of Mesenchymal Triple-Negative Breast Cancer: Evidence From a Phase 1 Trial of mTOR Inhibition in Combination With Liposomal Doxorubicin and Bevacizumab

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Targeting the Wnt/beta-catenin pathway in cancer: Update on effectors and inhibitors.

scientific article published on 13 November 2017

Targeting the molecular chaperone heat shock protein 90 (HSP90): Lessons learned and future directions ⬇️

scientific article published on November 28, 2012

Telomerase reverse transcriptase promoter alterations across cancer types as detected by next-generation sequencing: A clinical and molecular analysis of 423 patients

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Temporal and spatial effects and survival outcomes associated with concordance between tissue and blood KRAS alterations in the pan-cancer setting

scientific article published on 01 July 2019

The "shield sign" in two men with metastatic salivary duct carcinoma to the skin: cutaneous metastases presenting as carcinoma hemorrhagiectoides ⬇️

scientific article published on September 1, 2012

The Challenges of Tumor Mutational Burden as an Immunotherapy Biomarker

scientific article published on 14 October 2020

The Conundrum of Genetic "Drivers" in Benign Conditions

scientific article published on 07 April 2016

The Crossroads of Precision Medicine and Therapeutic Decision-Making: Use of an Analytical Computational Platform to Predict Response to Cancer Treatments

scientific article published on 09 January 2020

The FGFR Landscape in Cancer: Analysis of 4,853 Tumors by Next-Generation Sequencing

scientific article published on 15 September 2015

The Karabus Affair Speaks to Larger Issues for American Academic and Medical Centers ⬇️

scientific article published on May 1, 2013

The Marriage Between Genomics and Immunotherapy: Mismatch Meets Its Match

scientific article published on 23 October 2018

The Master Observational Trial: A New Class of Master Protocol to Advance Precision Medicine

scientific article published on 01 January 2020

The Mutational Landscape of Gastrointestinal Malignancies as Reflected by Circulating Tumor DNA.

scientific article published on 13 November 2017

The National Clinical Trials Network: Conducting Successful Clinical Trials of New Therapies for Rare Cancers

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The Prevalence and Impact of Hyperglycemia and Hyperlipidemia in Patients With Advanced Cancer Receiving Combination Treatment With the Mammalian Target of Rapamycin Inhibitor Temsirolimus and Insulin Growth Factor-Receptor Antibody Cixutumumab

scientific article published on 8 June 2015

The Urgent Need for Clinical Research Reform to Permit Faster, Less Expensive Access to New Therapies for Lethal Diseases.

scientific article published in October 2015

The biology of Hepatocellular carcinoma: implications for genomic and immune therapies

scientific article published on 30 August 2017

The changing face of phase 1 cancer clinical trials: new challenges in study requirements

scientific article published on April 2009

The checklist: BEST medical center employment requirements 2015.

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The clinical significance of tumor necrosis factor-alpha plasma level in patients having chronic lymphocytic leukemia

scientific article published on 01 August 2002

The effects of curcumin (diferuloylmethane) on body composition of patients with advanced pancreatic cancer

scientific article published on 27 February 2016

The immunocytokine scFv23/TNF targeting HER-2/neu induces synergistic cytotoxic effects with 5-fluorouracil in TNF-resistant pancreatic cancer cell lines

scientific article published on 22 October 2007

The importance of greater speed in drug development for advanced malignancies.

scientific article published on 30 March 2018

The influence of tumor necrosis factor-alpha -308 G/A and IL-6 -174 G/C on pain and analgesia response in lung cancer patients receiving supportive care

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The inverted pyramid of biomarker-driven trials

scientific article published on 2 August 2011

The paradox of cancer genes in non-malignant conditions: implications for precision medicine

scientific article published on 17 February 2020

The prognostic significance of cytokine levels in newly diagnosed acute myeloid leukemia and high-risk myelodysplastic syndromes

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The role of investigational therapy in management of patients with advanced metastatic malignancy

scientific article published on 08 December 2008

Therapeutic Implications of Epidermal Growth Factor Receptor (EGFR) in the Treatment of Metastatic Gastric/GEJ Cancer

scientific article published on 04 August 2020

Thrombopoietic factors in chronic bone marrow failure states: the platelet problem revisited

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Thymoma patients treated in a phase I clinic at MD Anderson Cancer Center: responses to mTOR inhibitors and molecular analyses

scientific article published on June 2013

Timing of palliative care referral and symptom burden in phase 1 cancer patients: a retrospective cohort study

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Topoisomerase expression and amplification in solid tumours: Analysis of 24,262 patients

scientific article published on 17 July 2017

Total Number of Alterations in Liquid Biopsies Is an Independent Predictor of Survival in Patients With Advanced Cancers

scientific article published on 24 March 2020

Toxicity of targeted therapy: Implications for response and impact of genetic polymorphisms

scientific article published on 17 May 2014

Transcriptomic silencing as a potential mechanism of treatment resistance

scientific article published on 04 June 2020

Transcriptomics and Solid Tumors: The Next Frontier in Precision Cancer Medicine

scientific article published on 17 September 2020

Transformation of human mesenchymal cells and skin fibroblasts into hematopoietic cells

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Transient severe hyperbilirubinemia after hepatic arterial infusion of oxaliplatin in patients with liver metastases

scientific article published on 08 October 2013

Treatment of Patients With Advanced Neurofibromatosis Type 2 With Novel Molecularly Targeted Therapies: From Bench to Bedside ⬇️

scientific article published on December 27, 2011

Treatment of chronic myelogenous leukemia as a paradigm for solid tumors: how targeted agents in newly diagnosed disease transformed outcomes

scientific article published on January 2012

Trichomegaly of the eyelashes after lung cancer treatment with the epidermal growth factor receptor inhibitor erlotinib

scientific article published in July 2008

Triple-negative breast cancer patients treated at MD Anderson Cancer Center in phase I trials: improved outcomes with combination chemotherapy and targeted agents

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Tumor Mutational Burden as an Independent Predictor of Response to Immunotherapy in Diverse Cancers

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Tumor mutational burden is not predictive of cytotoxic chemotherapy response

scientific article published on 24 June 2020

Turmeric and green tea: a recipe for the treatment of B-chronic lymphocytic leukemia

scientific article published on February 2009

Tyrosine kinase inhibitors and the dawn of molecular cancer therapeutics

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Ultimate fate of oncology drugs approved by the us food and drug administration without a randomized Trial

scientific article published on 13 October 2009

Uncommon tumors and exceptional therapies: paradox or paradigm?

scientific article published on 01 April 2007

Understanding Toxicities of Targeted Agents: Implications for Anti-tumor Activity and Management

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Unilateral Proptosis ⬇️

scientific article published on February 13, 2013

Unique Genomic Landscape of High-Grade Neuroendocrine Cervical Carcinoma: Implications for Rethinking Current Treatment Paradigms

scientific article published on 03 September 2020

Unique molecular landscapes in cancer: implications for individualized, curated drug combinations

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Unique molecular signatures as a hallmark of patients with metastatic breast cancer: implications for current treatment paradigms

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Universal Genomic Testing Needed to Win the War Against Cancer: Genomics IS the Diagnosis

scientific article published on 14 April 2016

Use of Liquid Biopsies in Clinical Oncology: Pilot Experience in 168 Patients

scientific article published on 16 May 2016

Utility of Genomic Analysis In Circulating Tumor DNA from Patients with Carcinoma of Unknown Primary

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Utility of Genomic Assessment of Blood-Derived Circulating Tumor DNA (ctDNA) in Patients with Advanced Lung Adenocarcinoma

scientific article published on 24 May 2017

VEGF and dual-EGFR inhibition in colorectal cancer

scientific article published in January 2015

VEGF-A Expression Correlates with TP53 Mutations in Non-Small Cell Lung Cancer: Implications for Antiangiogenesis Therapy

scientific article published on 11 February 2015

Validation of prognostic scoring and assessment of clinical benefit for patients with bone sarcomas enrolled in phase I clinical trials

scientific article published on 28 July 2016

Validation of the Royal Marsden Hospital prognostic score in patients treated in the Phase I Clinical Trials Program at the MD Anderson Cancer Center

scientific article published on 5 August 2011

Vascular endothelial growth factor and its relationship to inflammatory mediators

scientific article published on May 2007

Warning signal: Unaware of an in absentia conviction, South African cancer specialist jailed on return to the United Arab Emirates ⬇️

scientific article published on January 1, 2013

Weekly nab-Rapamycin in patients with advanced nonhematologic malignancies: final results of a phase I trial

scientific article

Xilonix, a novel true human antibody targeting the inflammatory cytokine interleukin-1 alpha, in non-small cell lung cancer

scientific article published on 31 March 2015

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