Search filters

List of works by Rui Daniel Prediger

A new naphthoquinone isolated from the bulbs of Cipura paludosa and pharmacological activity of two main constituents

scientific article published on 31 January 2011

A single neurotoxic dose of methamphetamine induces a long-lasting depressive-like behaviour in mice

scientific article published on 26 September 2013

Activation of adenosine A1 receptors reduces anxiety-like behavior during acute ethanol withdrawal (hangover) in mice.

scientific article published on 11 January 2006

Acyl ghrelin improves cognition, synaptic plasticity deficits and neuroinflammation following amyloid β (Aβ1-40) administration in mice.

scientific article published on 5 April 2017

Adenosine A1 receptor activation modulates N-methyl-d-aspartate (NMDA) preconditioning phenotype in the brain.

scientific article published on 31 December 2014

Adenosine A1 receptors modulate the anxiolytic-like effect of ethanol in the elevated plus-maze in mice.

scientific article published in September 2004

Age-related cognitive decline in hypercholesterolemic LDL receptor knockout mice (LDLr-/-): evidence of antioxidant imbalance and increased acetylcholinesterase activity in the prefrontal cortex

scientific article published in January 2012

Agmatine attenuates depressive-like behavior and hippocampal oxidative stress following amyloid β (Aβ1-40) administration in mice

scientific article published on 28 June 2018

Agmatine attenuates reserpine-induced oral dyskinesia in mice: Role of oxidative stress, nitric oxide and glutamate NMDA receptors

scientific article published on 12 June 2016

Altered emotionality leads to increased pain tolerance in amyloid beta (Abeta1-40) peptide-treated mice.

scientific article published on 2 April 2010

Amygdala levels of the GluA1 subunit of glutamate receptors and its phosphorylation state at serine 845 in the anterior hippocampus are biomarkers of ictal fear but not anxiety.

scientific article

Angiotensin II type 1/adenosine A 2A receptor oligomers: a novel target for tardive dyskinesia

scientific article

Antidepressant effects of creatine on amyloid β1-40-treated mice: The role of GSK-3β/Nrf2 pathway.

scientific article

Antidepressant- and anxiolytic-like activities of an oil extract of propolis in rats.

scientific article

Antidepressant-like effect of ursolic acid isolated from Rosmarinus officinalis L. in mice: Evidence for the involvement of the dopaminergic system

scientific article published on 25 August 2012

Anxiety in Parkinson’s disease: A critical review of experimental and clinical studies

scientific article published on August 31, 2011

Atorvastatin Prevents Cognitive Deficits Induced by Intracerebroventricular Amyloid-β1-40 Administration in Mice: Involvement of Glutamatergic and Antioxidant Systems.

scientific article published in April 2015

Atorvastatin Prevents Early Oxidative Events and Modulates Inflammatory Mediators in the Striatum Following Intranasal 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) Administration in Rats.

scientific article

Atorvastatin improves cognitive, emotional and motor impairments induced by intranasal 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) administration in rats, an experimental model of Parkinson's disease

scientific article published on March 30, 2013

Atorvastatin prevents hippocampal cell death, neuroinflammation and oxidative stress following amyloid-β1–40 administration in mice: Evidence for dissociation between cognitive deficits and neuronal damage

scientific article published on September 15, 2010

Behavioral and Neurochemical Consequences of Pentylenetetrazol-Induced Kindling in Young and Middle-Aged Rats

scientific article published on 13 September 2017

Behavioral phenotyping of Parkin-deficient mice: looking for early preclinical features of Parkinson's disease

scientific article

Blockade of adenosine A2A receptors reverses short-term social memory impairments in spontaneously hypertensive rats.

scientific article published on 8 December 2004

Blockade of adenosine and dopamine receptors inhibits the development of rapid tolerance to ethanol in mice.

scientific article published on 29 September 2005

Blockade of hippocampal bradykinin B1 receptors improves spatial learning and memory deficits in middle-aged rats

scientific article published on 24 August 2016

CX3CR1 Disruption Differentially Influences Dopaminergic Neuron Degeneration in Parkinsonian Mice Depending on the Neurotoxin and Route of Administration.

scientific article published on 24 September 2015

Caffeine Consumption plus Physical Exercise Improves Behavioral Impairments and Stimulates Neuroplasticity in Spontaneously Hypertensive Rats (SHR): an Animal Model of Attention Deficit Hyperactivity Disorder

scientific article published on 03 July 2020

Caffeine Mitigates the Locomotor Hyperactivity in Middle-aged Low-density Lipoprotein Receptor (LDLr)-Knockout Mice

scientific article published on 25 March 2016

Caffeine alleviates progressive motor deficits in a transgenic mouse model of spinocerebellar ataxia.

scientific article

Caffeine improves spatial learning deficits in an animal model of attention deficit hyperactivity disorder (ADHD) -- the spontaneously hypertensive rat (SHR).

scientific article published on 9 May 2005

Caffeine reverses age-related deficits in olfactory discrimination and social recognition memory in rats. Involvement of adenosine A1 and A2A receptors.

scientific article

Cellular prion protein (PrP(C)) modulates ethanol-induced behavioral adaptive changes in mice.

scientific article published on 26 June 2014

Cellular prion protein is present in dopaminergic neurons and modulates the dopaminergic system

scientific article published on 26 April 2014

Cellular prion protein modulates age-related behavioral and neurochemical alterations in mice.

scientific article published on 9 September 2009

Chronic Alcohol Intoxication and Cortical Ischemia: Study of Their Comorbidity and the Protective Effects of Minocycline.

scientific article published on 22 June 2016

Chronic Metabolic Derangement-Induced Cognitive Deficits and Neurotoxicity Are Associated with REST Inactivation

scientific article published on 14 June 2018

Chronic caffeine treatment during prepubertal period confers long-term cognitive benefits in adult spontaneously hypertensive rats (SHR), an animal model of attention deficit hyperactivity disorder (ADHD).

scientific article published on 25 June 2010

Chronic ethanol exposure during adolescence in rats induces motor impairments and cerebral cortex damage associated with oxidative stress

scientific article (publication date: 2014)

Chronic ethanol exposure during adolescence through early adulthood in female rats induces emotional and memory deficits associated with morphological and molecular alterations in hippocampus

scientific article published on 28 April 2015

Cipura paludosa attenuates long-term behavioral deficits in rats exposed to methylmercury during early development.

scientific article published on 5 May 2010

Connecting TNF-alpha signaling pathways to iNOS expression in a mouse model of Alzheimer's disease: relevance for the behavioral and synaptic deficits induced by amyloid beta protein.

scientific article

Decreased synaptic plasticity in the medial prefrontal cortex underlies short-term memory deficits in 6-OHDA-lesioned rats

scientific article

Depression as a Glial-Based Synaptic Dysfunction

scientific article

Developmental exposure to glyphosate-based herbicide and depressive-like behavior in adult offspring: Implication of glutamate excitotoxicity and oxidative stress.

scientific article published on 13 June 2017

Developmental exposure to manganese induces lasting motor and cognitive impairment in rats

scientific article

Does methylmercury-induced hypercholesterolemia play a causal role in its neurotoxicity and cardiovascular disease?

scientific article published on 17 August 2012

Effects of Agmatine on Depressive-Like Behavior Induced by Intracerebroventricular Administration of 1-Methyl-4-phenylpyridinium (MPP(+)).

scientific article published on 9 July 2015

Effects of Ethanolic Extract and Naphthoquinones Obtained from the Bulbs of Cipura paludosa on Short‐Term and Long‐Term Memory: Involvement of Adenosine A1 and A2A Receptors

scientific article published on December 31, 2012

Effects of acute administration of the hydroalcoholic extract of mate tea leaves (Ilex paraguariensis) in animal models of learning and memory.

scientific article published on 27 September 2008

Effects of caffeine in Parkinson's disease: from neuroprotection to the management of motor and non-motor symptoms.

scientific article

Effects of exercise on mitochondrial function, neuroplasticity and anxio-depressive behavior of mice

scientific article published on 26 April 2014

Effects of lifestyle modifications on cognitive impairments in a mouse model of hypercholesterolemia

scientific article published on 5 March 2013

Effects of pentylenetetrazole kindling on mitogen-activated protein kinases levels in neocortex and hippocampus of mice

scientific article published on 15 October 2014

Environmental enrichment improves cognitive deficits in Spontaneously Hypertensive Rats (SHR): relevance for Attention Deficit/Hyperactivity Disorder (ADHD).

scientific article published on 21 June 2009

Erratum to: Variables associated with physical health-related quality of life in Parkinson's disease patients presenting for deep brain stimulation.

scientific article published on 25 August 2016

Ethanolic extract from bulbs of Cipura paludosa reduced long-lasting learning and memory deficits induced by prenatal methylmercury exposure in rats.

scientific article published on 6 September 2012

Ethnobotany, phytochemistry and neuropharmacological effects of Petiveria alliacea L. (Phytolaccaceae): A review

scientific article published on March 2016

Evaluation of Nigrostriatal Neurodegeneration and Neuroinflammation Following Repeated Intranasal 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine (MPTP) Administration in Mice, an Experimental Model of Parkinson’s Disease

scientific article published on 21 May 2013

Exercise Improves Cognitive Impairment and Dopamine Metabolism in MPTP-Treated Mice

scientific article

Folic Acid Plus α-Tocopherol Mitigates Amyloid-β-Induced Neurotoxicity through Modulation of Mitochondrial Complexes Activity

scientific article published on 01 January 2011

Functional interaction between pre-synaptic α6β2-containing nicotinic and adenosine A2A receptors in the control of dopamine release in the rat striatum.

scientific article published on August 2013

Genetic deletion or antagonism of kinin B(1) and B(2) receptors improves cognitive deficits in a mouse model of Alzheimer's disease.

scientific article

Glucose-dependent insulinotropic peptide receptor expression in the hippocampus and neocortex of mesial temporal lobe epilepsy patients and rats undergoing pilocarpine induced status epilepticus

scientific article published on 23 December 2010

Guanosine Prevents Anhedonic-Like Behavior and Impairment in Hippocampal Glutamate Transport Following Amyloid-β1-40 Administration in Mice

scientific article published on 6 September 2016

Guanosine prevents depressive-like behaviors in rats following bilateral dorsolateral striatum lesion induced by 6-hydroxydopamine

scientific article published on 15 June 2019

Heavy Chronic Ethanol Exposure From Adolescence to Adulthood Induces Cerebellar Neuronal Loss and Motor Function Damage in Female Rats.

scientific article

High sucrose consumption induces memory impairment in rats associated with electrophysiological modifications but not with metabolic changes in the hippocampus.

scientific article

Hospital mortality of patients with severe traumatic brain injury is associated with serum PTX3 levels

scientific article published on 01 April 2011

Hypercholesterolemia induces short-term spatial memory impairments in mice: up-regulation of acetylcholinesterase activity as an early and causal event?

scientific article published on 29 October 2013

Increased sensitivity of adolescent spontaneously hypertensive rats, an animal model of attention deficit hyperactivity disorder, to the locomotor stimulation induced by the cannabinoid receptor agonist WIN 55,212-2.

scientific article published on 17 February 2007

Increased susceptibility to amyloid-β-induced neurotoxicity in mice lacking the low-density lipoprotein receptor

scientific article published in January 2014

Influence of environmental enrichment vs. time-of-day on behavioral repertoire of male albino Swiss mice.

scientific article

Interaction of curcumin with manganese may compromise metal and neurotransmitter homeostasis in the hippocampus of young mice.

scientific article published on 11 April 2014

Intranasal administration of neurotoxicants in animals: support for the olfactory vector hypothesis of Parkinson's disease.

scientific article published on 15 October 2011

Intranasal administration of sodium dimethyldithiocarbamate induces motor deficits and dopaminergic dysfunction in mice.

scientific article published on 29 March 2018

Lipopolysaccharide-Induced Striatal Nitrosative Stress and Impaired Social Recognition Memory Are Not Magnified by Paraquat Coexposure.

scientific article published on 23 January 2018

Lithium and valproate prevent olfactory discrimination and short-term memory impairments in the intranasal 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) rat model of Parkinson's disease.

scientific article published on 17 January 2012

Long-Term Neurobehavioral Consequences of a Single Ketamine Neonatal Exposure in Rats: Effects on Cellular Viability and Glutamate Transport in Frontal Cortex and Hippocampus

scientific article published on 02 July 2018

Manganese-exposed developing rats display motor deficits and striatal oxidative stress that are reversed by Trolox

scientific article published on 6 February 2013

Mechanisms involved in abdominal nociception induced by either TRPV1 or TRPA1 stimulation of rat peritoneum.

scientific article published in August 2013

Melatoninergic System in Parkinson's Disease: From Neuroprotection to the Management of Motor and Nonmotor Symptoms

scientific article

Methamphetamine Induces Anhedonic-Like Behavior and Impairs Frontal Cortical Energetics in Mice.

scientific article published on 19 October 2016

Mice with genetic deletion of the heparin-binding growth factor midkine exhibit early preclinical features of Parkinson's disease.

scientific article published on 8 February 2011

Mild cognitive deficits associated to neocortical microgyria in mice with genetic deletion of cellular prion protein.

scientific article

Minocycline mitigates motor impairments and cortical neuronal loss induced by focal ischemia in rats chronically exposed to ethanol during adolescence

scientific article published on 15 March 2014

Moderate traumatic brain injury increases the vulnerability to neurotoxicity induced by systemic administration of 6-hydroxydopamine in mice

scientific article published on 10 March 2017

Moderate-Intensity Physical Exercise Protects Against Experimental 6-Hydroxydopamine-Induced Hemiparkinsonism Through Nrf2-Antioxidant Response Element Pathway.

scientific article

Modulation of short-term social memory in rats by adenosine A1 and A(2A) receptors.

scientific article published on 9 December 2004

Neopterin acts as an endogenous cognitive enhancer.

scientific article published on 22 February 2016

Neuroprotection in Neurodegenerative Disease: From Basic Science to Clinical Applications.

scientific article published on 28 February 2017

Neuropsychological functioning and brain energetics of drug resistant mesial temporal lobe epilepsy patients.

scientific article published on 12 October 2017

Overexpression of cellular prion protein (PrP(C)) prevents cognitive dysfunction and apoptotic neuronal cell death induced by amyloid-β (Aβ₁₋₄₀) administration in mice.

scientific article

Parkin-knockout mice did not display increased vulnerability to intranasal administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).

scientific article published on 16 April 2013

Periodontitis and Alzheimer's Disease: A Possible Comorbidity between Oral Chronic Inflammatory Condition and Neuroinflammation.

scientific article published on 10 October 2017

Physical exercise improves motor and short-term social memory deficits in reserpinized rats.

scientific article published on 20 May 2009

Pilocarpine improves olfactory discrimination and social recognition memory deficits in 24 month-old rats.

scientific article published on 24 January 2006

Plasma levels of oxidative stress biomarkers and long-term cognitive performance after severe head injury

scientific article published on 01 July 2012

Positive correlation between elevated plasma cholesterol levels and cognitive impairments in LDL receptor knockout mice: relevance of cortico-cerebral mitochondrial dysfunction and oxidative stress.

scientific article published on 16 September 2011

Prevalence of headache in patients with Parkinson's disease and its association with the side of motor symptom onset.

scientific article published on 7 November 2013

Proanthocyanidin-rich fraction from Croton celtidifolius Baill confers neuroprotection in the intranasal 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine rat model of Parkinson's disease.

scientific article published on 8 October 2010

Propolis: A useful agent on psychiatric and neurological disorders? A focus on CAPE and pinocembrin components

scientific article published on 11 November 2020

Psychiatric disorders and health-related quality of life after severe traumatic brain injury: a prospective study

scientific article published in April 2012

Red wine consumption mitigates the cognitive impairments in low-density lipoprotein receptor knockout (LDLr-/-) mice

scientific article published on 07 January 2020

Region-specific alterations of AMPA receptor phosphorylation and signaling pathways in the pilocarpine model of epilepsy.

scientific article

Repeated cycles of binge-like ethanol exposure induce immediate and delayed neurobehavioral changes and hippocampal dysfunction in adolescent female rats

scientific article published on 09 May 2018

Role of Prefrontal Cortex on Recognition Memory Deficits in Rats following 6-OHDA-Induced Locus Coeruleus Lesion

scientific article published on 11 July 2020

Role of hormonal levels on hospital mortality for male patients with severe traumatic brain injury

scientific article published on 19 May 2014

Role of nicotine on cognitive and behavioral deficits in sepsis-surviving rats

scientific article published on 26 February 2013

Role of the glucose-dependent insulinotropic polypeptide and its receptor in the central nervous system: therapeutic potential in neurological diseases.

scientific article published on September 2010

Role of the macrophage inflammatory protein-1alpha/CC chemokine receptor 5 signaling pathway in the neuroinflammatory response and cognitive deficits induced by beta-amyloid peptide

scientific article

Rosmarinus officinalis L. hydroalcoholic extract, similar to fluoxetine, reverses depressive-like behavior without altering learning deficit in olfactory bulbectomized mice.

scientific article published on 18 June 2012

Running for REST: Physical activity attenuates neuroinflammation in the hippocampus of aged mice

scientific article published on 29 July 2016

Short bouts of mild-intensity physical exercise improve spatial learning and memory in aging rats: involvement of hippocampal plasticity via AKT, CREB and BDNF signaling.

scientific article published in October 2011

Single intranasal administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in C57BL/6 mice models early preclinical phase of Parkinson's disease.

scientific article published on 21 July 2009

Six weeks of voluntary exercise don't protect C57BL/6 mice against neurotoxicity of MPTP and MPP(+).

scientific article

Spatial reference memory deficits precede motor dysfunction in an experimental autoimmune encephalomyelitis model: the role of kallikrein-kinin system.

scientific article published on 15 June 2013

Succinobucol, a Non-Statin Hypocholesterolemic Drug, Prevents Premotor Symptoms and Nigrostriatal Neurodegeneration in an Experimental Model of Parkinson's Disease

scientific article published on 6 February 2016

Temporal Dissociation of Striatum and Prefrontal Cortex Uncouples Anhedonia and Defense Behaviors Relevant to Depression in 6-OHDA-Lesioned Rats.

scientific article published on 12 July 2015

Temporal development of behavioral impairments in rats following locus coeruleus lesion induced by 6-hydroxydopamine: Involvement of β3-adrenergic receptors

scientific article published on 05 April 2019

Tetrahydrobiopterin improves hippocampal nitric oxide-linked long-term memory

scientific article published on 11 June 2018

The Gender-Biased Effects of Intranasal MPTP Administration on Anhedonic- and Depressive-Like Behaviors in C57BL/6 Mice: the Role of Neurotrophic Factors

scientific article published on 28 May 2018

The cannabinoid CB2 receptor-specific agonist AM1241 increases pentylenetetrazole-induced seizure severity in Wistar rats.

scientific article published on 29 August 2016

The effects of physical exercise on nonmotor symptoms and on neuroimmune RAGE network in experimental parkinsonism.

scientific article published on 6 April 2017

The exercise redox paradigm in the Down's syndrome: improvements in motor function and increases in blood oxidative status in young adults.

scientific article

The influence of chromosome 4 on metabolism and spatial memory in SHR and SLA16 rat strains

scientific article published on 21 May 2019

The risk is in the air: Intranasal administration of MPTP to rats reproducing clinical features of Parkinson's disease.

scientific article published on 14 August 2006

Time course evaluation of behavioral impairments in the pilocarpine model of epilepsy

scientific article published on 12 January 2016

Treadmill Exercise Attenuates L-DOPA-Induced Dyskinesia and Increases Striatal Levels of Glial Cell-Derived Neurotrophic Factor (GDNF) in Hemiparkinsonian Mice

scientific article published on 02 August 2018

Ursolic acid affords antidepressant-like effects in mice through the activation of PKA, PKC, CAMK-II and MEK1/2.

scientific article published on 24 May 2017

Variables associated with physical health-related quality of life in Parkinson's disease patients presenting for deep brain stimulation.

scientific article published on 25 July 2016