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List of works by Joris Winderickx

A Mitochondria-Associated Oxidative Stress Perspective on Huntington's Disease

scholarly article by Ju Zheng published in January 2018

A Novel Tau Antibody Detecting the First Amino-Terminal Insert Reveals Conformational Differences Among Tau Isoforms

scientific article published on 31 March 2020

A genome-wide imaging-based screening to identify genes involved in synphilin-1 inclusion formation in Saccharomyces cerevisiae

scientific article published on 21 July 2016

A network-based approach to identify substrate classes of bacterial glycosyltransferases.

scientific article

A specific mutation in Saccharomyces cerevisiae adenylate cyclase, Cyr1K176M, eliminates glucose- and acidification-induced cAMP signalling and delays glucose-induced loss of stress resistance

scientific article

A yeast-based model of alpha-synucleinopathy identifies compounds with therapeutic potential

scientific article published on 27 December 2005

Activation state of the Ras2 protein and glucose-induced signaling in Saccharomyces cerevisiae.

scientific article

Aggresome formation and segregation of inclusions influence toxicity of α-synuclein and synphilin-1 in yeast.

scientific article published on October 2011

Ceramide involvement in apoptosis and apoptotic diseases.

scientific article published on June 2006

Cytosolic pH is a second messenger for glucose and regulates the PKA pathway through V-ATPase

scientific article

Decreased Vacuolar Ca2+ Storage and Disrupted Vesicle Trafficking Underlie Alpha-Synuclein-Induced Ca2+ Dysregulation in S. cerevisiae

scientific article published on 08 May 2020

Deletion of SFI1, a novel suppressor of partial Ras-cAMP pathway deficiency in the yeast Saccharomyces cerevisiae, causes G(2) arrest.

scientific article

Differential roles for the low-affinity phosphate transporters Pho87 and Pho90 in Saccharomyces cerevisiae ⬇️

scientific article published on March 1, 2011

Endonuclease G mediates α-synuclein cytotoxicity during Parkinson's disease

scientific article

Evidence for adenylate cyclase as a scaffold protein for Ras2-Ira interaction in Saccharomyces cerevisie

scientific article published on 8 February 2014

Expression levels of the yeast alcohol acetyltransferase genes ATF1, Lg-ATF1, and ATF2 control the formation of a broad range of volatile esters.

scientific article

Genome-wide expression analysis reveals TORC1-dependent and -independent functions of Sch9.

scientific article published on 28 August 2008

Glucose and sucrose: hazardous fast-food for industrial yeast?

scientific article published in October 2004

Glucose-sensing and -signalling mechanisms in yeast.

scientific article

Hexokinase 2; Tangled between sphingolipid and sugar metabolism

scientific article published on 26 July 2016

Inferring transcriptional modules from ChIP-chip, motif and microarray data

scientific article

Joined in death: highlights of the Sixth International Meeting on Yeast Apoptosis in Leuven, Belgium, 30 April-4 May 2008.

scientific article

Lentiviral delivery of the human wild-type tau protein mediates a slow and progressive neurodegenerative tau pathology in the rat brain

scientific article published on 23 April 2013

Level of M(IP)2C sphingolipid affects plant defensin sensitivity, oxidative stress resistance and chronological life-span in yeast

scientific article published on 3 March 2006

Life in the midst of scarcity: adaptations to nutrient availability in Saccharomyces cerevisiae

scientific article published on February 2010

Molecular mechanisms linking the evolutionary conserved TORC1-Sch9 nutrient signalling branch to lifespan regulation in Saccharomyces cerevisiae

scientific article published on 11 October 2013

Neuron-to-neuron wild-type Tau protein transfer through a trans-synaptic mechanism: relevance to sporadic tauopathies

scientific article published on 30 January 2014

PKA and Sch9 control a molecular switch important for the proper adaptation to nutrient availability.

scientific article

Protein folding diseases and neurodegeneration: lessons learned from yeast

scientific article published on 11 February 2008

Protein phosphatase 2A on track for nutrient-induced signalling in yeast

scientific article

Recent Insights on Alzheimer's Disease Originating from Yeast Models

scientific article published on 03 July 2018

Rim15 and the crossroads of nutrient signalling pathways in Saccharomyces cerevisiae

scientific article

Role of the ribosomal quality control machinery in nucleocytoplasmic translocation of polyQ-expanded huntingtin exon-1.

scientific article

SKN1, a novel plant defensin-sensitivity gene in Saccharomyces cerevisiae, is implicated in sphingolipid biosynthesis

scientific article

SNCA (α-synuclein)-induced toxicity in yeast cells is dependent on sirtuin 2 (Sir2)-mediated mitophagy

scientific article published on 23 August 2012

Segregation of protein aggregates involves actin and the polarity machinery

scientific article published on 01 November 2011

Serine-409 phosphorylation and oxidative damage define aggregation of human protein tau in yeast

scientific article published on December 2010

Synphilin-1 enhances α-synuclein aggregation in yeast and contributes to cellular stress and cell death in a Sir2-dependent manner

scientific article

TOR and PKA signaling pathways converge on the protein kinase Rim15 to control entry into G0.

scientific article

Tau monoclonal antibody generation based on humanized yeast models: impact on Tau oligomerization and diagnostics

scientific article

The AMPK/SNF1/SnRK1 fuel gauge and energy regulator: structure, function and regulation.

scientific article published on 26 September 2011

The Ccr4-Not complex independently controls both Msn2-dependent transcriptional activation--via a newly identified Glc7/Bud14 type I protein phosphatase module--and TFIID promoter distribution.

scientific article

The Saccharomyces cerevisiae alcohol acetyl transferase Atf1p is localized in lipid particles

scientific article

The deafness gene DFNA5 induces programmed cell death through mitochondria and MAPK-related pathways

scientific article published on 16 July 2015

The protein kinase Sch9 is a key regulator of sphingolipid metabolism in Saccharomyces cerevisiae.

scientific article

The splicing mutant of the human tumor suppressor protein DFNA5 induces programmed cell death when expressed in the yeast Saccharomyces cerevisiae

scientific article published on 25 July 2012

The yeast protein kinase Sch9 adjusts V-ATPase assembly/disassembly to control pH homeostasis and longevity in response to glucose availability

scientific article

Yeast as a Model for Alzheimer's Disease: Latest Studies and Advanced Strategies.

scientific article published on January 2016

Yeast as a model for medical and medicinal research

scientific article

Yeast as a model system to study tau biology.

scientific article published on 6 April 2011

Yeast buddies helping to unravel the complexity of neurodegenerative disorders.

scientific article published on 12 May 2016

Yeast models of Parkinson's disease-associated molecular pathologies.

scientific article published on 16 February 2017

Yeast stress, aging, and death

scientific article published on 02 December 2013

pH homeostasis in yeast; the phosphate perspective

scientific article published on 30 August 2017

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