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List of works by Matthias Schiedel

A Continuous, Fluorogenic Sirtuin 2 Deacylase Assay: Substrate Screening and Inhibitor Evaluation

scientific article published on 20 January 2016

Aminothiazoles as Potent and Selective Sirt2 Inhibitors: A Structure-Activity Relationship Study

scientific article

BET bromodomain ligands: Probing the WPF shelf to improve BRD4 bromodomain affinity and metabolic stability

scientific article published on 15 May 2018

Chemical Epigenetics: The Impact of Chemical and Chemical Biology Techniques on Bromodomain Target Validation

scientific article published on 14 November 2019

Chemically Induced Degradation of Sirtuin 2 (Sirt2) by a Proteolysis Targeting Chimera (PROTAC) Based on Sirtuin Rearranging Ligands (SirReals).

scientific article

Chromo-pharmacophores: photochromic diarylmaleimide inhibitors for sirtuins

Fluorescence-based screening assays for the NAD⁺-dependent histone deacetylase smSirt2 from Schistosoma mansoni.

scientific article published on 16 October 2014

Fragment-Based Identification of Ligands for Bromodomain-Containing Factor 3 of Trypanosoma cruzi

scientific article published on 17 November 2020

Selective Sirt2 inhibition by ligand-induced rearrangement of the active site.

scientific article

Small molecules as tools to study the chemical epigenetics of lysine acetylation

scientific article published on 27 June 2018

Structure-Based Development of an Affinity Probe for Sirtuin 2

scientific article

Synthesis and biological evaluation of 8-hydroxy-2,7-naphthyridin-2-ium salts as novel inhibitors of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE)

The Current State of NAD(+) -Dependent Histone Deacetylases (Sirtuins) as Novel Therapeutic Targets

scientific article published on 17 January 2017

Validation of the Slow Off-Kinetics of Sirtuin-Rearranging Ligands (SirReals) by Means of Label-Free Electrically Switchable Nanolever Technology

scientific article published on 06 November 2019

[HIV-1 eradication with the "shock and kill" strategy]

scientific article published on 01 May 2010

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